Best Large Grants for Nonprofit Organizations in South Carolina

Kappa Alpha Psi Foundation Scholarships

The Foundation Scholarships are merit-based and awarded to qualified students with a consideration of financial need. All recipients shall be in pursuit of a baccalaureate degree from an accredited college or university and as described by the respective scholarship criteria. Most scholarships are for one year, non-renewable unless otherwise indicated in the award description. 

Community Foundation of Washington County Maryland

We are one of more than 750 similar tax-exempt public charities throughout the United States that work to make their community a better place to live. We are a local organization staffed by residents of the community and led by a board of trustees who have an in-depth knowledge of the issues that shape our County.

This Community Foundation was created by and for the people of Washington County MD, and exists to improve the quality of life for all of our citizens, now and for generations to come, by building community endowments, addressing needs through grant making and providing leadership on key community issues.

About Our Scholarships

The Community Foundation of Washington County, MD offers more than 100 scholarships for graduating high school students and non-traditional students in continuing education.

Meritus Healthcare Foundation Scholarship Fund

This fund provides scholarships to deserving students from any Washington County public or private high school accepted into a designated health care program.

The Ono Initiative Grant by the Ono Pharma Foundation supports innovative research in Chemical Biology, aiming to transform human health. It welcomes proposals from Principal Investigators (PIs) at nominated institutions, focusing on groundbreaking solutions and promoting the development of young scientists. Grants of up to $1,035,000 over three years are available, fostering collaboration and transformative research aligned with the foundation's mission.

The Klingenstein-Simons Fellowship Awards in Neuroscience support early-career investigators conducting basic or clinical research focused on neurological and psychiatric disorders. Awardees receive $150,000 annually for three years, aimed at fostering innovative research that contributes to understanding and treating these disorders. The fellowship encourages applications from underrepresented groups and prioritizes candidates with promising scientific careers who may not have received substantial prior funding, promoting collaboration and mentorship in the neuroscience community.

The Research Enhancement Award Program (REAP) aims to boost basic and clinical research at health professional and graduate schools that have historically received limited NIH funding. By supporting small-scale research projects led by faculty, REAP fosters student engagement in significant research endeavors, enhancing their educational experience. Eligible institutions must grant advanced degrees in health professions and have received under $6 million in NIH support in four of the last seven years, promoting broader participation in the nation's biomedical research efforts.

The Institutional Research Grants (IRG) program by the American Cancer Society provides essential seed funding for newly independent investigators to launch cancer research projects. Aimed at junior faculty, these grants offer $120,000 annually for three years, supporting the development of preliminary results necessary for competing for larger national grants. Eligible applicants must be at US academic institutions and hold the rank of Associate or Full Professor, with a proven track record in research and mentorship.

The American Cancer Society (ACS) and the American Society for Radiation Oncology (ASTRO) co-fund the Clinician Scientist Development Grant (CSDG), aimed at advancing the research careers of clinician scientists in radiation oncology. Eligible applicants are full-time faculty members at U.S. institutions with a doctoral degree and an active clinical license. The grant supports research for 3 to 5 years, providing $135,000 annually for direct costs, plus allowable indirect costs, while encouraging diversity in applications.

The Clinician Scientist Development Grant (CSDG) by the American Cancer Society supports full-time faculty aiming to become independent clinician scientists while maintaining clinical practice. Eligible applicants must hold a doctoral degree, an active clinical license, and have clinical care experience. The grant provides funding of $135,000 annually for 3 to 5 years, including allowable indirect costs, to advance cancer research in key priority areas.

The Breed Promotion Grant Program, offered by the American Morgan Horse Association (AMHA), supports AMHA clubs and Morgan-related organizations in promoting the Morgan horse breed. Eligible entities can request funding for various promotional activities. In 2021, AMHA awarded nine grants across the U.S. and Australia, demonstrating their commitment to breed promotion. This grant aims to enhance the visibility and appreciation of Morgans within the equestrian community.

The American Cancer Society's Mentored Research Grants for Postdoctoral Fellowships (PF) aim to support emerging researchers in their training programs, fostering their transition to independent cancer research careers. Eligible candidates include US citizens or non-citizens with valid visas who have completed their doctoral degrees within the last four years. The fellowship offers funding for up to three years, with stipends of $66,000 to $70,000 annually, alongside allowances for health insurance and professional development.

The U.S. Hillman Prize for Magazine Journalism, awarded by the Sidney Hillman Foundation, recognizes outstanding journalism that serves the common good. Open to global journalists, it requires works to be published in English and accessible to a U.S. audience within the past year. Winners receive a $5,000 honorarium and a certificate at the annual ceremony in New York City. The foundation prioritizes stories with U.S. impact across diverse topics.

The U.S. Hillman Prize for Newspaper Journalism, awarded by the Sidney Hillman Foundation, recognizes outstanding journalism that serves the common good. Open to global journalists, entries must be published in English and accessible to U.S. audiences within the last year. Winners receive a $5,000 honorarium and a certificate at a New York City ceremony. The foundation also honors work related to racial and economic justice through additional awards. Entries should focus on impactful stories.

The Mission Boost Grants (MBG) by the American Cancer Society aim to enhance cancer research by funding projects that translate into human testing. These grants support investigators at all levels, offering resources for innovative clinical projects. The program consists of two funding stages: Stage I focuses on developing clear milestones for new treatments, while Stage II supports patient testing, ultimately contributing to advancements in cancer care and treatment.

The Discovery Boost Grants (DBG) offered by the American Cancer Society support innovative and high-risk exploratory cancer research. These grants, available for up to two years with a funding limit of $125,000 annually plus indirect costs, aim to generate preliminary data that can lead to further funding opportunities. Eligible applicants include independent investigators with a doctorate and a full-time faculty position, fostering advancements in cancer research across multiple priority areas.

The Myelodysplastic Syndromes (MDS) Research Fund Grant, established by the Vera and Joseph Dresner Foundation, aims to enhance research and treatment of MDS and related blood disorders. This fund supports innovative projects addressing etiology, biology, genetics, prognosis, treatment, symptom management, and quality of life. It offers up to $125,000 for Early Career Awards and $250,000 for Established Investigator Awards, facilitating significant advancements in the field.

The Bolick Foundation Grant, established in 1967, supports nonprofit 501(c)(3) organizations that promote the Christian faith. Located in Conover, NC, the foundation emphasizes grant-making to strengthen religious, charitable, and educational initiatives. Applicants must be registered in the USA and possess a tax identification number. Importantly, the foundation does not provide grants to individuals, ensuring that funds are directed towards collective community impact. For further details, please refer to the FAQs on their official website.

Saginaw Area Health Care Administrators Scholarship

The Saginaw Area Health Care Administrators Scholarship was established in 1987 to help advance health care for the elderly and ill elderly. The scholarship provides cash awards to assist employees of association members in meeting educational expenses. Each year, employees in the areas of administration, nursing, dietary, maintenance, and other health-related occupations are invited to apply for scholarships.

The Player Foundation Grant, offered by the NFL Foundation, supports the charitable initiatives of current and former NFL players through their nonprofit organizations. Eligible applicants must be vested under the Bert Bell/Pete Rozelle NFL Retirement Plan and operate a tax-exempt organization. This grant does not guarantee funding and should not be relied upon in annual budgeting. Organizations must have been established for at least three years and be capable of functioning without NFL Foundation support.

The Shakespeare in American Communities: Apprenticeships program by Arts Midwest offers grants of up to $30,000 to support paid apprenticeships for emerging theater professionals across the U.S. This initiative aims to enhance community-based theater activities, providing essential on-the-job training for early-career administrators and technicians, while fostering engagement with Shakespeare's works. Organizations of all sizes are encouraged to apply, ensuring diverse representation and opportunities in the arts.

The Disaster Relief and Resilience Scholarship supports residents of western North Carolina whose education funding has been affected by Hurricane Helene. Offered by the North Carolina Community Foundation, this scholarship is available for undergraduate and graduate students attending two- or four-year colleges. The minimum award is $1,000, aimed at helping students overcome financial hardships caused by the disaster and continue their educational pursuits.

Kiwanis Club of North Modesto

We are a service club of men and women whose primary goal is to help children and young people around the world, starting in Modesto, CA.

Scholarships

The members of the Kiwanis Club of North Modesto (founded in 1966) and the Kiwanis Club of Modesto (founded in 1923) are joining forces to award $2,000 scholarships to as many as 32 students for the 2026-27 academic year. Each year, members of these two clubs perform countless hours of community service through fundraisers, then donate these funds back to nonprofits and young people in our community. It is the hope of the two clubs that scholarship recipients in their adult life will give back to their communities as members of a community service club.

Goals

• To encourage public or private high school graduates (within the boundaries of the Modesto High School District) to pursue education goals, preferably at a California community college, four-year college or university or at a technical/vocational school.

• To recognize academic achievement and to invest in the future of young scholars. 
• To recognize young scholars who have demonstrated a commitment to volunteerism and community service

The NIDCD Cooperative Agreement for Clinical Trials in Communication Disorders (U01) invites applications to support clinical trials that require FDA oversight, aim to establish efficacy, or pose significant risks. This initiative, managed by the NIH, seeks to enhance interventions for communication disorders and encourages collaboration between NIDCD Project Scientists and investigators. Proposals are due by 5 PM local time, with Letters of Intent recommended 30 days prior to the deadline.

About the Foundation

Kern Community Foundation is a vibrant nonprofit enterprise with a powerfully simple mission of growing community and growing philanthropy.

Scholarships

Kern Community Foundation manages more than two dozen scholarship funds. Community stakeholders have created these scholarships to honor their loved ones, to support higher education, and to foster the improvement of students as they pursue their diverse ambitions. Students have access to all our scholarship resources through one simple application.

David Moore Agricultural Scholarship Fund

Established in 2005, the David Moore Agricultural Scholarship Fund (“Fund”), in memory of David Moore, is a permanently endowed scholarship fund. The Fund provides academic support to graduates of Kern County high schools who wish to pursue a career in agriculture. 

The Fund provides financial assistance to students who are U.S. citizens, and graduates of a Kern County high school who demonstrate motivation, perseverance, and a sincere desire to pursue a bachelor’s degree from an accredited college or university, and who wish to pursue a career in agriculture. Students are required to have a minimum cumulative grade point average of 3.0 at the time of application

About the Foundation

Kern Community Foundation is a vibrant nonprofit enterprise with a powerfully simple mission of growing community and growing philanthropy.

Scholarships

Kern Community Foundation manages more than two dozen scholarship funds. Community stakeholders have created these scholarships to honor their loved ones, to support higher education, and to foster the improvement of students as they pursue their diverse ambitions. Students have access to all our scholarship resources through one simple application.

The Caratan Family Scholarship Fund

The Caratan Family Scholarship Fund was established in 2018. The permanently endowed scholarship fund provides academic support to graduates of Kern County high schools who wish to study STEM (Science, Technology, Engineering, or Mathematics).

The Lozier Foundation

Formed in 1986, The Lozier Foundation is a family foundation funded by Allan and Dianne Lozier. The foundation’s focus is education, social services and issues involving women and children with an emphasis on the inner city and underrepresented populations.

Our Mission: The Lozier Foundation’s mission is to improve the quality of life for the underrepresented communities in the Omaha/Metro area.

Grants

Funding Priorities

• Education
• Women & Girls
• North Omaha Initiatives
• Human Services

Grantseekers wishing to apply to the Lozier Foundation should begin by reviewing the Mission, Values, Funding Priorities and Funding Eligibility Statements.

The Lozier Foundation grant applications include: Capital Application; Education Application; General Application; and Program Application.

Organizations may receive general operating, program, and capital grants. While The Lozier Foundation prefers to provide ongoing general operating support, organizations can receive a program and/or capital grant in the same calendar year.

Lozier Foundation Education Application

The Education Application follows the foundation guidelines provided here.

The Lozier Foundation

The Lozier Foundation is a private family foundation based in Omaha, Nebraska, funded by Allan and Dianne Lozier. The Foundation supports nonprofit organizations working to expand opportunity, strengthen communities, and improve quality of life for people and families who have historically had less access to resources.

The Foundation’s grantmaking is grounded in a long-term commitment to Omaha and the surrounding region. We are especially interested in work that helps level the playing field, supports people during important moments of need or transition, and gives individuals and families greater ability to make choices about their own lives and futures.

The Foundation’s support has historically focused on established nonprofit organizations working in areas such as education, human services, youth development, health, family stability, and community well-being. While those areas describe much of our grantmaking, they are not intended to serve as fixed categories or a comprehensive list.

The Foundation is selective in its grantmaking. We generally support organizations with a meaningful operating history, capable leadership, sound governance, financial discipline, and a demonstrated ability to serve the community effectively. The Foundation does not typically support early-stage organizations, small projects or organizations with limited reach, or requests that fall outside our geographic and charitable priorities.

The Foundation also considers whether a request reflects a clear understanding of the existing community landscape. We are generally skeptical of efforts that duplicate services already being provided effectively by other organizations, particularly when collaboration, coordination, or partnership would better serve the community. Organizations seeking support should be prepared to explain how their work fits within the broader field, who they collaborate with, and why the proposed work is needed.

Grants

Grantseekers wishing to apply to the Lozier Foundation should begin by reviewing the Mission, Values, Funding Priorities and Funding Eligibility Statements.

The Lozier Foundation grant applications include: Capital Application; Education Application; General Application; and Program Application.

Organizations may receive general operating, program, and capital grants. While The Lozier Foundation prefers to provide ongoing general operating support, organizations can receive a program and/or capital grant in the same calendar year.

Lozier Foundation General Application

Funding Priorities

• Education
• Women & Girls
• North Omaha Initiatives
• Human Services

The General Application follows the foundation guidelines provided here.

The Lozier Foundation

The Lozier Foundation is a private family foundation based in Omaha, Nebraska, funded by Allan and Dianne Lozier. The Foundation supports nonprofit organizations working to expand opportunity, strengthen communities, and improve quality of life for people and families who have historically had less access to resources.

The Foundation’s grantmaking is grounded in a long-term commitment to Omaha and the surrounding region. We are especially interested in work that helps level the playing field, supports people during important moments of need or transition, and gives individuals and families greater ability to make choices about their own lives and futures.

The Foundation’s support has historically focused on established nonprofit organizations working in areas such as education, human services, youth development, health, family stability, and community well-being. While those areas describe much of our grantmaking, they are not intended to serve as fixed categories or a comprehensive list.

The Foundation is selective in its grantmaking. We generally support organizations with a meaningful operating history, capable leadership, sound governance, financial discipline, and a demonstrated ability to serve the community effectively. The Foundation does not typically support early-stage organizations, small projects or organizations with limited reach, or requests that fall outside our geographic and charitable priorities.

The Foundation also considers whether a request reflects a clear understanding of the existing community landscape. We are generally skeptical of efforts that duplicate services already being provided effectively by other organizations, particularly when collaboration, coordination, or partnership would better serve the community. Organizations seeking support should be prepared to explain how their work fits within the broader field, who they collaborate with, and why the proposed work is needed.

Grants

Grantseekers wishing to apply to the Lozier Foundation should begin by reviewing the Mission, Values, Funding Priorities and Funding Eligibility Statements.

The Lozier Foundation grant applications include: Capital Application; Education Application; General Application; and Program Application.

Organizations may receive general operating, program, and capital grants. While The Lozier Foundation prefers to provide ongoing general operating support, organizations can receive a program and/or capital grant in the same calendar year.

Lozier Foundation Program Application

Funding Priorities

• Education
• Women & Girls
• North Omaha Initiatives
• Human Services

The Program Application follows the foundation guidelines provided here.