Best Large Grants for Nonprofit Organizations in South Carolina

Neuroscience & Society Grants

Applicants may request up to $150,000 in funding for projects over a period of up to 18 months.

Neuroscience and society is the interdisciplinary study of how neuroscience informs and reflects society, and practical work to put these ideas into action. Neuroscience and society includes fields where neuroscience interfaces with the world, such as ethics, law, humanities, medicine, arts, social sciences, policy, education, journalism, and public engagement. This list is meant to be illustrative, not exhaustive. Other disciplines may fall within the purview of neuroscience and society. 

While neuroscience and society is not the same as neuroethics, bioethics, or science and technology studies, there are areas of overlap. 

Another way we think about it: Neuroscience & society is a paradigm for how we can teach neuroscience to people, train people to do societally relevant neuroscience-focused work, and engage diverse communities of people to shepherd the development and application of neuroscience.   

The National Institute on Aging is announcing a Notice of Funding Opportunity for the Claude D. Pepper Older Americans Independence Centers (OAICs) award. This initiative aims to establish centers of excellence in geriatrics research and education to enhance the independence of older adults. Applicants are encouraged to identify a research focus that fosters collaboration and education in aging. Though applications are not currently being accepted, this notice allows potential applicants to prepare meaningful projects. The P30 activity code will be utilized.

The WASPC Traffic Safety Grants provide funding for law enforcement agencies to enhance traffic safety initiatives. Agencies can apply for specific traffic safety supplies, including lidar and radars, with maximum award amounts clearly outlined. Eligible applicants must demonstrate participation in statewide traffic initiatives, while ineligible requests include those for replacing existing equipment. This funding aims to prioritize traffic safety enforcement and improve community safety through targeted efforts.

The Maria and Paolo Alessio Southern Italy Scholarship, offered by the UNICO Foundation, supports students of Southern Italian descent pursuing a degree at an accredited U.S. college or university. Valued at $2,500, this scholarship aims to empower students who demonstrate academic excellence with a minimum GPA of 2.7. Eligible applicants must be U.S. citizens and can be Freshmen, Sophomores, or Juniors, continuing their studies in the 2026-2027 academic year.

The UNICO Foundation Inc. offers the Cancer Research & Prevention Grant to support vital research projects addressing various types of cancer, including colon, breast, and prostate cancer. Established in 1962, this non-profit organization aims to enhance lives through charitable contributions and educational initiatives. Grants are exclusively for direct research and preventive measures, ensuring that all funds are utilized effectively. This initiative reflects UNICO's commitment to combating cancer and its impact on individuals and families across the United States.

The KaBOOM! Adventure Courses Grant Program offers funding to create engaging playspaces for older children and teens. This initiative encourages community involvement through a collaborative design and build process, aiming to address the need for physical activity in low-income areas. Eligible applicants include organizations that serve youth and can demonstrate community support. Grants are available on a rolling basis, with a focus on priority cities impacted by recent events, including rural Colorado and Hurricane Harvey-affected Texas communities.

Scholarships

Since awarding our first $500 scholarship in 1987, the Saginaw Community Foundation has awarded college scholarships to area students totaling more than $13.7 million, thanks to our generous donors. Each year, over 500 college-bound or career and technical education students benefit from our scholarship awards.

Our single application process makes it easy to potentially qualify for one or more of our 260+ scholarships.

Gerald and Inez O’Brien Scholarship

Gerald and Inez O’Brien both grew up in Saginaw County and were married for over 30 years before Gerald passed away at an early age. 

Gerald and Inez both believed strongly in education and supporting family and friends. In addition, they each treasured their lifetime neighbors and knew the importance of building relationships with their community neighbors and enjoying life. 

This scholarship memorial fund was created by their daughter, Ann Pavlik, and son, Dr. Keith O’Brien. The fund will strive to recognize those giving back to the community and those facing challenges head on, even when life throws roadblocks along the way.  

Scholarships

Since awarding our first $500 scholarship in 1987, the Saginaw Community Foundation has awarded college scholarships to area students totaling more than $13.7 million, thanks to our generous donors. Each year, over 500 college-bound or career and technical education students benefit from our scholarship awards.

Our single application process makes it easy to potentially qualify for one or more of our 260+ scholarships.

Iles Family Conservation Scholarship

The Iles Family Conservation Scholarship was established by Doug and Sandy Iles in memory of Clarence “Buck” Iles. A lifelong passion for conservation balanced with practical application is what Buck Iles stood for. A very avid sportsman, he was actively involved with leadership in the Michigan United Conservation Club and Saginaw Field and Stream, among others.

For more than 20 years, Buck Iles helped establish and operate the Saginaw Field and Stream Club annual scholarship raffle which supported over 40 different scholarships. Buck passed away in 2005 and this scholarship was established to continue the great raffle tradition that now no longer exists.

Doug and Sandy established this scholarship fund in “Dad’s” memory. Recipients should be students with an active interest in environmental issues. Although not limited to, emphasis will be placed on awarding this scholarship to a resident of Saginaw County. A minimum 3.0 GPA and a student who has the need for educational financial support are key determinants.

Scholarships

Since awarding our first $500 scholarship in 1987, the Saginaw Community Foundation has awarded college scholarships to area students totaling more than $13.7 million, thanks to our generous donors. Each year, over 500 college-bound or career and technical education students benefit from our scholarship awards.

Our single application process makes it easy to potentially qualify for one or more of our 260+ scholarships.

James P. Konieczka Memorial Scholarship

The James P. Konieczka Memorial Scholarship was established by his three children, Bryan, Amy, and Katie, to honor their father’s wishes after his passing in 2016 following a courageous year-long battle with cancer.

Jim believed in the value of a college education, but he also understood that not everyone wants to pursue this post-secondary education path. It was his wish that this scholarship be made available to someone seeking Career and Techincal Education (CTE) training or to someone seeking a traditional college degree.

The Seeding Critical Advances for Leading Energy Technologies (Scaleup) Ready initiative by ARPA-E invites applications for funding to advance transformative energy technologies. This program supports innovative projects that demonstrate potential for significant market disruption and emphasizes rigorous project management and technology risk mitigation. Eligible organizations must have inventions conceived during an ARPA-E award, reported in the iEdison system, and hold relevant U.S. patent applications. For further details, visit ARPA-E's website.

Middlesex County Medical Society Foundation

The Middlesex County Medical Society Foundation, founded in 1964 and was initially funded by contributions from the first mass polio vaccination in our county.

MCMS Foundation Scholarship Fund

Middlesex County Medical Society Foundation is an independent nonprofit organization that awards scholarships to deserving students from Middlesex County, New Jersey for the study of medicine. Scholarships are awarded to deserving students who are enrolled in an accredited medical school.

The CDC's NCIPC is seeking research proposals to tackle implementation challenges in providing linkage to care services for individuals with opioid use disorder (OUD). This initiative encourages partnerships with public health entities and local healthcare champions to create actionable, evidence-based strategies. The goal is to enhance care access and ensure comprehensive overdose prevention services are available in real-world healthcare settings, thereby improving outcomes for those at risk of opioid overdose.

Community Foundation Serving Western Virginia

Our Community Foundation was established in Roanoke in 1988. With our growth, we expanded into the Martinsville/Henry County area in 2005. Today, we administer many hundreds of named endowment funds ranging in size from a minimum of $10,000 to millions of dollars. To date, donors have also committed very significant resources to the Foundation through future estate gifts.

Our Mission:Enabling people who love their community to easily give back.

Scholarships

Community Foundation Serving Western Virginia, the region’s community foundation, administers a variety of scholarships to reward and assist capable and deserving students based on the criteria established by the fund donors.

Jim Barker Scholarship Fund

Fund provides higher educational scholarship assistance to deserving students.

Scholarships

Since awarding our first $500 scholarship in 1987, the Saginaw Community Foundation has awarded college scholarships to area students totaling more than $13.7 million, thanks to our generous donors. Each year, over 500 college-bound or career and technical education students benefit from our scholarship awards.

Our single application process makes it easy to potentially qualify for one or more of our 260+ scholarships.

Judge Gary R. McDonald Memorial Scholarship

January 2004 marked the passing of a true champion of justice and compassion for the men and women of Michigan. Judge Gary R. McDonald, beloved father and friend, served the citizens of Saginaw and the rest of Michigan for over 30 years.

In honor of his esteemed service, the family and colleagues of this respected Michigan leader have created the Judge Gary R. McDonald Memorial Scholarship Fund. Its purpose is to grant students of Saginaw County the financial means to pursue a career in a law-related field so that Judge McDonald’s unrelenting pursuit of justice may continue in his honor.

Awarding this scholarship to those in need serves Judge McDonald’s personal mission of inspiring the hearts and minds of our youth to serve our communities for the good of all.

Scholarships

Since awarding our first $500 scholarship in 1987, the Saginaw Community Foundation has awarded college scholarships to area students totaling more than $13.7 million, thanks to our generous donors. Each year, over 500 college-bound or career and technical education students benefit from our scholarship awards.

Our single application process makes it easy to potentially qualify for one or more of our 260+ scholarships.

Junior League of the Great Lakes Bay Region Scholarship

Junior League of the Great Lakes Bay Region is an organization of women committed to promoting volunteerism, developing the potential of women and improving the community through the effective action and leadership of trained volunteers. Its purpose is exclusively educational and charitable. The Junior League of the Great Lakes Bay Region is an organization that welcomes for membership all women regardless of age, race, creed, religion or national origin, who demonstrate an interest in and commitment to volunteerism.

The league has had many fundraising events in its history, always with the purpose of returning monies to the community through varied and needed projects. The Junior League of the Great Lakes Bay Region Scholarship is one of those projects.

The Access Fund's Climbing Conservation Grant supports projects that enhance climbing access and conserve the climbing environment across the U.S. Grants typically range from $1,000 to $4,000, with larger requests considered for projects of national significance. Emphasizing local collaboration and measurable outcomes, this program seeks action-oriented initiatives that promote climber responsibility and community engagement, while also adhering to environmental regulations and securing necessary approvals.

Kenny Simon Scholarship

Kenny Simon, a member of the class 1988, met an untimely death in the summer of 1985. Kenny’s parents and friends established a scholarship fund in his honor.

The interest from this fund is to be used annually to provide a scholarship for a deserving member of the graduating class. In the event the scholarship if not applied for by students, the money will be contributed to the Special Olympics Program.

Mark Gradeless Welding Scholarship

This award was created in 2021 to honor the life of Mark “Grady” Gradeless. A 1977 graduate of Columbia City Joint High School, he worked at Dana Corporation, where he tirelessly serviced machines from the age of 18 until his retirement. “Grady” was a member of the United Auto Workers, Steelworkers Union and could often be found in his barn fixing something or tinkering. He was known for his daredevil shenanigans, practical jokes, patience, hard work, common sense advice and ability to uplift those around him. “Grady” was an amazing Dad, Grandfather, Great-Grandfather and friend to all who knew and loved him. This award is for a student attending Ivy Tech Community College for the pursuit of a welding certificate.

Horizon of Hope Scholarship

Balancing the responsibilities of family and work can be challenging for anyone, but for single parents who want to improve their lives by continuing their education, juggling the added responsibilities can seem downright overwhelming.

The Horizons of Hope Fund was established to recognize and encourage single parents who have returned to school. Created to help lighten the load, Horizons of Hope assistance can be used for tuition expenses, books, supplies, transportation, childcare, or other living expenses.

Up to $500 per semester is available to single parents.

Bob Brittain Memorial Scholarship/CCHS Alumni Scholarship

Presented by the Columbia City High School Alumni Association

Criteria are the same for a two year degree and four year degree. This scholarship is one-time and non-renewable.

The ideal recipient of this scholarship will be a CCHS graduate who has been actively involved in several extra-curricular activities, major service activities, and have a grade point average reflective of respectable academic growth. This student will have a four year involvement in the activities listed below. This student will also be fully involved in high school classes during the final trimester of the senior year

The BRAIN Initiative's funding opportunity aims to support the establishment of facilities at minority-serving and IDeA-eligible institutions for the production and distribution of brain cell type-specific reagents. These reagents will enhance neuroscience research by enabling precise manipulation and access to brain cell types, facilitating advancements in understanding circuit functions in various species. The initiative encourages collaboration among awardees to optimize the use of these essential resources across the neuroscience community.

The Environmental Health Sciences Core Centers Program (P30) invites grant applications to support innovative research in environmental health. These centers serve as critical hubs for advancing the goals of the 2025-2029 NIEHS Strategic Plan, providing essential infrastructure and resources for collaborative research. By fostering community engagement and translational research, the program aims to enhance understanding of the connections between environmental factors, human biology, and disease, ultimately improving public health outcomes.

Background

The Foundation for Physical Therapy Research is the research funding organization for the American Physical Therapy Association (APTA) and is a registered 501(c)(3) . Our vision is to shape the future of health through physical therapy research. Our mission is fund research and develop researchers to optimize movement and improve the health of society.

Through the generosity of our donors and community of supporters, o ur sole purpose for the past 46 years has been to fund physical therapy research and researchers through grants, scholarships, and fellowships. Through our investments in PhD students and early career researchers , we are creating a pipeline of highly skilled and capable researchers . They are b uilding our knowledge of and evidence about effective and innovative physical therapy practices, tools, guidelines, and education across the spectrum of our professional specialties.

Our growing number of larger grants allow s us to fund both emerging and established researchers who have been helping build the physical therapy evidence base in priority areas and help define the value of physical therapy for patients and clients, health care professionals , and payers. Through the generosity of our donors, we have created a sustained pipeline for future researchers and of research funding to help launch careers and advance the profession’s evidence -based practices.

The Jimmy A. Young Memorial Education Recognition Award, offered by the American Respiratory Care Foundation, honors contributions to respiratory care education. Up to $1,000 is available for students enrolled in accredited respiratory care programs, provided they meet GPA requirements and submit necessary recommendations. This award includes a certificate, airfare, lodging, and registration for the AARC Congress, aiming to support deserving candidates in their educational pursuits.

The FPTR: Acute Care Research Grant aims to support high-quality research relevant to acute care physical therapy practice. With a total funding of $80,000, this grant encourages innovative studies that can enhance the understanding and application of physical therapy methods. The Foundation for Physical Therapy Research prioritizes projects that address pressing clinical questions and contribute to the evidence base for effective practices while promoting equity in health care.

Community Foundation for the Land of Lincoln

The Community Foundation offers many advantages to donors, professional advisors, nonprofit organizations and the community at large. We constantly strive to ensure that the giving process is as streamlined and safe as possible so our donors can focus on the most important aspect of philanthropy - helping others.

Scholarship Program

The Community Foundation serves the counties of Cass, Christian, Logan, Macoupin, Menard, Montgomery, Morgan and Sangamon in central Illinois, and administers an annual scholarship program for approximately 50 scholarship funds.

Fred E. Droste Memorial Scholarship

Graduating senior from a high school in Macoupin or Montgomery Counties who is pursuing a degree in a STEAM-related field.

Scholarships

Since awarding our first $500 scholarship in 1987, the Saginaw Community Foundation has awarded college scholarships to area students totaling more than $13.7 million, thanks to our generous donors. Each year, over 500 college-bound or career and technical education students benefit from our scholarship awards.

Our single application process makes it easy to potentially qualify for one or more of our 260+ scholarships.

Armin “Bun” and Lorraine Rinness Memorial Scholarship Fund

The Armin “Bun” and Lorraine Rinness Memorial Scholarship Fund honors Armin “Bun” and Lorraine Rinness by supporting Saginaw County students pursuing college or Career and Technical Education (CTE) training. This fund provides need-based assistance to help local students continue their education and achieve long-term success.