Best Large Grants for Nonprofit Organizations in South Carolina

The NIA Postdoctoral Fellowship Award aims to enhance diversity in the translational research workforce for Alzheimer's disease and related dementias (AD/ADRD). This fellowship supports promising candidates from diverse backgrounds in developing essential translational research skills. The program emphasizes interdisciplinary approaches to treatment, prevention, and early detection of AD/ADRD while providing research experience under the guidance of mentors in clinical trials, fostering a diverse and effective research community.

The NIA Predoctoral Fellowship Award aims to enhance diversity in the translational research workforce focusing on Alzheimer's disease and related dementias. This funding opportunity supports promising predoctoral candidates from underrepresented backgrounds, fostering their research training and skills in various aspects of AD/ADRD. By encouraging interdisciplinary teamwork, the program seeks to develop a diverse workforce capable of contributing significantly to the prevention, treatment, and management of these conditions.

Kothari Family Fund Healthcare Scholarship

This scholarship, made in memory of Kathy Jowsey, is for graduates of Ten Broeck Academy/Franklinville High School who demonstrate financial need, have worked hard academically, and exemplify school spirit through extracurricular activities, sports and/or volunteerism. Preference for this scholarship will be given to students majoring in business, accounting, sports management or journalism.

The Intervention Research to Improve Native American Health initiative aims to enhance health outcomes in Native American communities through innovative research. This program supports studies focused on health promotion, disease prevention, and culturally informed treatment strategies. Key deadlines for grant applications are October 21, 2025, and January 7, 2026. By addressing health disparities and leveraging community strengths, the initiative fosters sustainable interventions tailored to specific cultural contexts.

The Intervention Research to Improve Native American Health (R34) aims to support research that enhances health interventions for Native American populations. This includes studying the efficacy of health promotion and disease prevention strategies, culturally informed treatments, and addressing existing health disparities. The initiative encourages community-based solutions that are sustainable and adaptable to various Native American tribes. Key deadlines for grant applications are set for October 2025 and 2026, with additional dates for AIDS-related proposals.

The Community Foundation of Carroll County supports nearly 70 academic, sports, special circumstances, and 4-H scholarships. Search scholarships by name, or sort by application type.

The Ryan Legacy Scholarship

Melanie Ryan was an incredible mother, wife, friend, and nurse for almost 30 years. Her kindness, generosity, and compassion will be remembered forever by those who had the honor to know and love her. She passed away from Metastatic Triple Negative Breast Cancer in June of 2024. Her husband Tom was the love of her life and also and incredibly kind and caring husband, father, manager and friend. He passed away from Hodgkins Lymphoma in November of 2022. This scholarship remembers this beautiful couple by assisting graduating high school seniors and current college students in pursuing a college degree. Preference will be given to student athletes in memory of Tom’s love of sports and students pursuing a healthcare related degree in memory of Melanie’s incredible nursing skills and heart.

Every Battle Creek area resident shall have the resources to access post-secondary education and training.

Your dreams matter — and we want to help you achieve them. Whether you’re a graduating high school senior, an adult returning to school, or a graduate student pursuing advanced education, we’re here to support you by opening doors to opportunity.

Beyond tuition, many funds support total cost of attendance — books, fees, equipment, and in some cases childcare or transportation.

Checks are made payable to the educational institution indicated on the follow-up and mailed directly to the educational institution. Checks are typically mailed in early August.

Raymond J. Pontoni Entrepreneur Scholarship Fund

The fund was established in Honor of the memory of Raymond J. Pontoni, past CEO of Nottawa Gardens Corporation and Athens Community Leader to assist Athens graduating seniors and adults seeking to further their education and business needs, through training programs in the skilled trades, associate degrees, apprenticeships, or certificate programs, and to help aid the creation and development of their Entrepreneural Goals and economic ventures.

The Grief Reach Grants: Community Education Cycle, funded by the National Alliance for Children's Grief (NACG), aims to empower organizations that support grieving youth. With $10,000 grants available, the initiative enhances access to essential bereavement resources and education, addressing the needs of children coping with loss. This program is crucial as 1 in 12 children will experience the death of a loved one by age 18, highlighting the urgent need for support in diverse communities.

The Jazz Road Creative Residencies Grant Program, initiated by South Arts, supports professional jazz artists in the U.S. by removing financial barriers to their creative practices. This initiative aims to enhance artistic growth through flexible residency activities, fostering community engagement and innovative collaborations. By providing crucial funding, it encourages artists to explore new creative visions, connect with diverse audiences, and build meaningful partnerships across the country, thereby enriching the jazz landscape.

Every Battle Creek area resident shall have the resources to access post-secondary education and training.

Your dreams matter — and we want to help you achieve them. Whether you’re a graduating high school senior, an adult returning to school, or a graduate student pursuing advanced education, we’re here to support you by opening doors to opportunity.

Beyond tuition, many funds support total cost of attendance — books, fees, equipment, and in some cases childcare or transportation.

Checks are made payable to the educational institution indicated on the follow-up and mailed directly to the educational institution. Checks are typically mailed in early August.

Kristin & Michael Bauman Scholarship Fund

Kristin Bauman, as a teacher and consultant, taught hearing impaired students in Pennsylvania and Calhoun County, Michigan for over 30 years. She had lost the majority of her own hearing in her youth which served to motivate her to help others with this disability. After retiring, she was approached by a former hearing impaired student who as an adult, wished to return to college. Kristin was reminded of how difficult it was to find the financial resources to go to college. In researching the scholarships available to students with disabilities, she found there were few scholarships offered for students with disabilities especially within the Calhoun County, Michigan area. Students with hearing impairments have to work harder than most to not only obtain but succeed in higher education. Kristin and her family would like to help hearing impaired students, as well as their future teachers, make higher education a reality through this scholarship.

Every Battle Creek area resident shall have the resources to access post-secondary education and training.

Your dreams matter — and we want to help you achieve them. Whether you’re a graduating high school senior, an adult returning to school, or a graduate student pursuing advanced education, we’re here to support you by opening doors to opportunity.

Beyond tuition, many funds support total cost of attendance — books, fees, equipment, and in some cases childcare or transportation.

Checks are made payable to the educational institution indicated on the follow-up and mailed directly to the educational institution. Checks are typically mailed in early August.

Homer FFA Alumni Scholarship Fund

Established in 1983 the Homer FFA Alumni is a support group for the Homer FFA chapter. The Homer FFA chapter was established in 1948. The Homer FFA Alumni Chapter focuses on premier leadership, personal growth and career success through agricultural education. Homer FFA Alumnus have received national recognition as an Outstanding Alumni Affiliate. The Homer FFA Alumni Scholarship was established in 2002. The Homer FFA Alumni highly encourage current FFA members to reach their fullest potential through furthering their education, beyond high school.

The Arthur L. and Elaine V. Johnson Foundation Grants, established in 1990, aim to support organizations that assist individuals with physical disabilities through guide dogs and other assistance animals. The foundation also prioritizes wildlife conservation efforts, particularly for endangered species and their habitats. Grants are awarded to charitable organizations under specific IRS classifications, focusing on long-term impactful projects. Applications for ongoing operational funding are discouraged, and priority is given to conservation activities that are science-based.

At the Community Foundation for Muskegon County, we work with donors, grantees, and advisors to address key community issues.

Margaret and Dr. Paul Borton Music Scholarship

This scholarship has been made possible by the generosity of Dr. Paul Borton, who established the Margaret and Dr. Paul Borton Music Scholarship of the Community Foundation for Muskegon County in memory of his wife, Margaret Borton. Margaret "Maggie" Borton arrived in Muskegon in the late 40s, bringing with her the rich heritage and culture of South Carolina. Not having had the opportunity in her youth to pursue music, she sought ways to include it in her daily life, enjoying the many concerts and festivals available in our area. Maggie always admired the talented youth she met in Muskegon's musical community. Knowing of her dream, her love for people and her passion for music, Maggie's husband, Paul established the Margaret Borton Music Scholarship Fund in her memory to provide scholarship assistance to Muskegon County students who will major in music in college.

ASPCA PRO

ASPCApro.org provides tools and resources for animal welfare professionals, veterinary personnel and volunteers. We take a progressive approach to helping the country's at-risk animals, promoting cutting edge research to advance the field.

ASPCA Research Grants

The American Society for the Prevention of Cruelty to Animals® (ASPCA®) research grants fund high-quality research with a clear potential to benefit animals, either directly or through effecting systems-level change. Proposals to extend existing studies, focused on other disciplines, will also be considered if they can clearly demonstrate substantial potential benefit to animal welfare.

This year we are soliciting proposals in the following six research areas:

• Access to Veterinary Care (AVC) Research
• Applied Behavior Research
• Cruelty Research
• Farm Animal Welfare Research
• Psychological Trauma Research
• Shelter Research

Proposals focused on evaluating the effectiveness of a program or service must demonstrate methodological rigor and a clear plan to produce generalizable scientific knowledge. Please view eligibility information for specific projects from the research area you are interested in. 

Psychological Trauma Research

Proposals related to developing and validating novel approaches to the objective documentation of animal cruelty and neglect in the absence of physical trauma (i.e., documenting psychological trauma) in dogs. Proposals are encouraged from any relevant discipline (e.g., physiology, psychology, ethology). Of particular interest is research that focuses on objective measures, including biomarkers and quantitative behavioral phenotyping.

At the Community Foundation for Muskegon County, we work with donors, grantees, and advisors to address key community issues.

Julie Herrick Easterly Memorial Scholarship

This scholarship has been made possible by the generosity of the family and friends of Julie Herrick-Easterly, who established the Julie HerrickEasterly Memorial Scholarship of the Community Foundation for Muskegon County. Julie Herrick-Easterly, an only child and part of an established family tradition of journalism, worked as a copy editor for various newspapers across the country. Her father, Robert Herrick, was editor of the Muskegon Chronicle for 17 years. At age 34, Julie died from a terminal illness. Following Julie's death, her parents established this scholarship in her memory. Awards from the scholarship are given to a Muskegon area graduating senior who plans to pursue a career in journalism. The award represents an acknowledgment of the student's past achievements in this area of study. To the credit of the Herricks, Julie's love for journalism will always be remembered, and the family tradition will be perpetuated through the lasting gift of education.

The Wayfinders: Launching Spiritual Activists Grant Program, initiated by the Presbyterian Church (U.S.A.), empowers college students to pursue anti-racism and anti-poverty initiatives on their campuses. This innovative program connects participants with mentorship and financial resources to develop justice and spirituality projects. With support from the 1001 New Worshiping Communities initiative, students will receive coaching and guidance throughout the academic year, culminating in a retreat to share experiences and insights.

Who We Are

The GHACF is a team of dedicated individuals passionate about improving the lives of everyone in our community – connecting people, resources and solutions that create a lasting impact.

The GHACF is your partner. We can’t succeed alone – our work is possible only through the combined efforts of our nonprofit partners, community members, and passionate individuals. We are a bridge to help you make things happen and impact our community, together. We will walk alongside you to support and assist you in your philanthropic goals, now and forever.

Floto-Peel Family Fund

Medicine.

Checks are made payable to and mailed directly to the college after you have returned the required scholarship acceptance paperwork, thank you note, and photo. This is usually by early August.

Rainin Visionary Scientist Award 

The Kenneth Rainin Foundation believes that early support for innovative ideas can lead to improvements in preventing, predicting, diagnosing and treating Inflammatory Bowel Disease (IBD). Our Health grantmaking enables researchers worldwide to test ideas, gather and share data, and collaborate to advance the understanding of IBD.

The Rainin Visionary Scientist Award will provide grants of $300,000 each over two years to support three outstanding postdoctoral investigators whose work has the potential to advance the understanding of IBD and related biological systems. This award is designed to help postdocs based in the US who are actively preparing to transition to an independent faculty position develop innovative research programs and strengthen their trajectory toward independent scientific careers. By supporting promising scientists early in their careers, the Foundation seeks to accelerate discoveries that may ultimately improve the lives of people living with Crohn’s disease and ulcerative colitis.

Competitive proposals will demonstrate:

• A novel or creative scientific approach
• Strong potential to advance understanding of IBD biology or treatment
• Clear intellectual leadership from the applicant
• Feasible research aims that can be accomplished within two years
• A strong mentorship environment that supports career development

The Foundation particularly values projects that introduce new ideas, technologies or conceptual approaches to the study of IBD and relevant scientific disciplines.

Funds may be used for postdoctoral salary support, supplies, other direct research expenses necessary to complete the proposed work and travel to relevant scientific meetings. Awardees are expected to attend the Rainin Foundation Innovations Symposium during the award period. Economy/coach air travel costs for this meeting in San Francisco should be included in the budget.

The award provides $300,000 over two years. The grant period is October 1, 2026-September 30, 2028.

Indigo Hope Foundation: First Responder Wellness Grant

Supporting programs that provide mental health resources, training, family support, and wellness services for our first responders.

Key Focus Areas:

• Mental Health Support
• Family Services
• Training Programs
• Peer Support

Example Programs We Fund:

• Critical incident stress management
• Family counseling services
• Peer support programs
• Wellness and resilience training

The Creative Capital Award, established in 1999, provides unrestricted project grants ranging from $15,000 to $50,000 for innovative artistic works in various disciplines. It supports artists in visual arts, performing arts, film, and literature through a democratic, open-call process. Awardees receive professional development resources and mentorship over a five-year relationship. Additionally, recipients are automatically considered for the State of the Art Prize, which offers a $10,000 grant to one artist from each U.S. state.

The Hershey Heartwarming Young Heroes GYSD Grant supports youth-led projects for Youth Service Month and Global Youth Service Day. Open to U.S. and Canadian youth aged 5-25, grants of $250 or $500 are available, depending on volunteer engagement. Projects should address community needs and foster inclusivity among diverse youth volunteers. Successful applications will partner with local organizations and focus on relationship-building. A total of $50,000 in grants will be awarded, encouraging meaningful community service.

Achievement Scholarship for Students with a History of Chronic Illness (FN)

Essay:

• Tell us about your experiences/struggles with your chronic illness and what you have done to overcome it.

Awards:

• One time award of $1,500.

The Tommy Aaron/Charlie Aaron Foundation Scholarship, managed by the North Georgia Community Foundation, supports graduating seniors from Hall County or Gainesville City public schools and Lakeview Academy. This $10,000 scholarship, distributed over four years, promotes academic achievement and integrity through golf. Eligible applicants must have a minimum GPA of 2.5, demonstrate financial need, and exhibit strong character traits. This initiative aims to empower local students to pursue higher education while honoring the values of sportsmanship and respect.

The Irene Yamamoto Arts Writers Fellowship supports emerging writers focusing on music criticism. This fellowship encourages applicants to submit writing samples that critically analyze live or recorded music. Eligible candidates must be U.S. citizens or residents, 18 or older, and have less than two years of publication experience. The award includes unrestricted funds to advance their careers, alongside opportunities for publication and public speaking at the Democracy Center.

The IEEE Oceanic Society Grant, offered by the Institute of Electrical and Electronics Engineers, supports up to $5,000 for initiatives focusing on ocean engineering, including ocean protection and renewable energy. This grant aims to empower educators and professionals to engage pre-university students in STEM fields. With multiple funding levels available, this program encourages community outreach and aims to inspire the next generation of technology innovators through hands-on learning and collaboration.

Community Foundation of Northwest Mississippi

The Community Foundation of Northwest Mississippi manages 314 donor-established funds and has disbursed over $48 million to support more than 1,000 charitable organizations and activities recommended by its donors, as well as charitable programs established by the foundation. Established in 2002 with a generous grant from the Maddox Foundation, the Community Foundation is an independent 501(c)3 charitable organization. The Foundation serves Bolivar, Coahoma, DeSoto, Leflore, Marshall, Panola, Quitman, Sunflower, Tallahatchie, Tate, Tunica and Yalobusha counties. 

The Reese and Joelle Norris Service through Music Scholarship

The Community Foundation, CoroRio, and MidSouth Music Institute is pleased to offer a $500 college scholarship: The Reese and Joelle Norris Service through Music Scholarship. We are grateful to Reese and Joelle Norris for more than ten years of service to CoroRio and the MidSouth Music Institute. Together, they have nearly 50 years of teaching thousands of all ages throughout the MidSouth and across the country.

Starting in the Spring of 2024, the scholarship will be awarded each year to a student who is currently involved in CoroRio, plans to pursue a career related to music, and has demonstrated a passion for serving others through music, like Reese and Joelle. 

Cumberland Community Foundation ("CCF") manages more than 60 scholarship endowment funds created by local individuals, families, civic organizations, and corporations who want to provide a path to higher education for future generations. 

Each year, Cumberland Community Foundation announces more than $1,000,000 in college scholarships to students from southeastern North Carolina.

Fayetteville Firefighters Scholarship

Must be both an active uniform Fayetteville firefighter and planning to attend accredited college/university within 6 months.