Best Large Grants for Nonprofit Organizations in South Carolina

The Porphyrias Fund, managed by the HealthWell Foundation, aims to alleviate financial burdens for underinsured patients suffering from porphyrias, a group of eight disorders characterized by the accumulation of porphyrins in the body. The fund assists with prescription drug copays and insurance premiums, offering up to $4,000 in financial aid. Established to ensure no patient lacks necessary treatment due to costs, the foundation has awarded over $1.2 billion since 2004, supporting more than 1.1 million patients.

The Dollie Lane Harp Memorial Scholarship Fund for Classical Music, established by Ruth Harp Gibson, honors her mother’s legacy through music. This scholarship is available for students majoring in classical music at accredited U.S. universities or conservatories. Eligible candidates include graduating seniors from specific Texas high schools who have participated in music during their studies. Awards range from $500 to over $5,000, with payments made directly to educational institutions.

The Tillie Odam Memorial Scholarship, established by John Odam in honor of his mother, supports Big Country high school seniors and alumni pursuing Health Information Technology or Allied Health programs. This scholarship, offered by the Community Foundation of Abilene, provides financial assistance to students enrolling in accredited vocational or college programs. Awards range from $500 to over $5,000, with payments sent directly to educational institutions for the fall and spring semesters.

The HealthWell Foundation's Inborn Metabolic or Genetic Bile Acid Deficiency Vitamins and Supplements Fund provides essential financial assistance for individuals facing significant health challenges. By covering copays, deductibles, and related expenses, the fund aims to alleviate the financial burden on underinsured patients. With a commitment to enhancing healthcare access, the Foundation has awarded over $1.2 billion since its inception, ensuring that vital treatments remain accessible to those in need.

The African-American Community Foundation - Waverly Glover Scholarship, offered by The Dayton Foundation, supports African-American students pursuing higher education at Central State University or Wilberforce University. Eligible candidates must be business or accounting majors with junior or senior status, enrolled full-time, and maintain a GPA of 2.5 or higher. This scholarship honors Waverly Glover's legacy, promoting educational opportunities and empowering the next generation of leaders in the community.

The Betsy Frabotta Educate and Engage Scholarship for Q+ Youth honors the legacy of a dedicated educator and community builder, providing $2000 to outstanding LGBTQ+ and ally students in the Miami Valley. This scholarship supports individuals who demonstrate a commitment to learning and equity, encouraging applicants who are actively involved in advocacy and community service. By fostering inclusion and empowerment, this initiative aims to honor the fight against discrimination and promote a fulfilling life for all.

The SAVC Presentation Award, offered by the Society for Vascular Surgery, recognizes vascular surgeons who have completed clinical research in office-based or ambulatory surgical center settings. This award encourages innovative research on topics such as drug-eluting technology, patient safety, and health disparities. Three recipients will present their findings, promoting diversity, equity, and inclusion in vascular care. Applications are welcomed from SVS members and eligible trainees, emphasizing community engagement and impactful health projects.

The SAVC Research Seed Grant, offered by the Society for Vascular Surgery, aims to support innovative research in vascular health. With a focus on quality improvement and actionable insights, this grant provides $10,000 to each of three selected recipients. Eligible applicants include SVS Active or Candidate Members and trainees in outpatient vascular practices. The grant emphasizes diversity and community engagement, encouraging projects that address health disparities and enhance patient care through various innovative approaches.

The Esther Roth Gillette Registered Nurse Scholarship, established by The Dayton Foundation in 2017, supports students enrolled in accredited nursing programs. This scholarship aims to empower future nurses by providing financial assistance to those demonstrating community service and financial need. The Dayton Foundation, serving Greater Dayton since 1921, is dedicated to enhancing local philanthropic efforts and addressing pressing community issues, making this scholarship a vital resource for aspiring healthcare professionals.

The Gough Family Scholarship, established in 2021 by The Dayton Foundation, aims to support graduating high school seniors from specific Dayton zip codes who exhibit a strong work ethic and plan to pursue education in a STEM-related field or business. Applicants must demonstrate financial need and have a history of successful employment. This scholarship reflects the Foundation's commitment to fostering education and enhancing opportunities for youth in the community.

The Helen and Howard Smith Nursing Scholarship, established by The Dayton Foundation in 2002, supports students pursuing LPN or BSN degrees. Eligible applicants must be sophomores or above enrolled in nursing programs within Montgomery or Greene counties and demonstrate financial need. Preference is given to non-traditional students. The Dayton Foundation, a key philanthropic entity since 1921, aims to enhance community welfare through charitable initiatives, focusing on education, health services, and cultural advancement.

The Amyloidosis Fund, managed by the HealthWell Foundation, provides essential financial assistance to underinsured patients facing treatment costs for Amyloidosis. The program covers prescription copays, insurance premiums, and related expenses, ensuring that patients can access necessary medications without financial strain. With a maximum award of $8,000, the fund aims to alleviate the burden of healthcare costs for those diagnosed with this complex disease, promoting better health outcomes and quality of life for patients across the United States.

The African-American Community Foundation - Yokley-Gamblin Family Scholarship, established in 2019, aims to support underrepresented ethnic minority students from Montgomery County in their educational journeys. This scholarship is awarded to students who demonstrate financial need, excel in community involvement, and maintain a GPA of 3.0 or below. Recipients can use the funds for tuition at accredited institutions, including technical schools and colleges, fostering educational opportunities for deserving candidates.

The Helen T. Bianca Nursing Scholarship, offered by the Community Foundation of Greater New Britain, supports high school seniors from New Britain and Berlin who are pursuing nursing degrees at accredited institutions. Applicants must show financial need and commitment to community service through volunteer work. A personal essay detailing their dedication to nursing and community impact is required. This scholarship aims to foster future nurses dedicated to improving healthcare in their communities.

The Louis J. (Mattioli) Matt Music Scholarship, offered by the Community Foundation of Greater New Britain, supports graduating seniors from public high schools in New Britain, Newington, or Plainville. Eligible students must pursue a bachelor's degree in music education or performance, demonstrate outstanding musical talent, and rank in the top 25% of their class. Financial need is also a key consideration, encouraging talented young musicians to further their education and hone their skills.

The Charles Hall & Beatrice Joy Kolar Scholarship Fund, managed by the Crown Point Community Foundation, supports local students pursuing education in the trade industry. This fund provides financial assistance to graduating high school seniors, college students, and adult learners, focusing on those with greater financial need. Scholarships are non-renewable and are awarded based on specific criteria set by donors to enhance educational opportunities in South Lake County.

The Bryan C. Niedert Memorial Scholarship Fund, administered by the Crown Point Community Foundation, supports graduating high school seniors, college students, and adult learners from Crown Point and Lowell High Schools. Applicants must meet specific GPA requirements and pursue education in trades or business fields. This scholarship aims to enhance the community's quality of life by providing financial assistance tailored to meet diverse educational needs, ensuring that the next generation can thrive.

The Vets Serving Vets Scholarship, established by North Central Washington Vets Serving Vets through the Community Foundation of NCW, supports residents of Chelan and Douglas counties who have been honorably discharged from the U.S. Armed Forces. This scholarship is aimed at individuals pursuing full-time college education, helping them achieve their academic goals while honoring their service. Since its inception in 2017, it has played a vital role in assisting veterans in their educational journeys.

The Wenatchee Valley Street Rods Scholarship, managed by the Community Foundation of North Central Washington, aims to support students pursuing education in automotive fields or health sciences at Wenatchee Valley College. Eligible applicants include high school seniors from Chelan County or Eastmont School District, as well as current students in medically related programs. Applicants must demonstrate good citizenship and criminal record eligibility. This scholarship can be renewed with reapplication.

The Women’s Service League of North Central Washington Scholarship, established in 2013, aims to support female students from various high schools in the region. This scholarship prioritizes applicants who demonstrate community involvement, leadership skills, and a minimum GPA of 2.75. Special consideration is given to those who have faced significant challenges and to children or grandchildren of League members, fostering a commitment to volunteerism and community improvement.

The LearningTimes Foundation is excited to announce the Fall 2025 Emerging Educational Filmmaker Grant, which aims to support new filmmakers creating educational films. With funding up to $10,000, this initiative seeks to empower storytellers to address significant societal issues and foster meaningful discussions through their work. The grant encourages diverse narratives, especially from underrepresented communities, and aims to connect projects with specific learning communities for impactful engagement.

The Rhoden Fellowship, supported by ESPN and administered by the United Negro College Fund, is a year-long program designed to empower students from historically Black colleges and universities (HBCUs). Participants will serve as correspondents, creating multimedia content for Andscape, covering major sports events, and producing a bi-weekly podcast. This opportunity not only fosters journalistic skills but also promotes engagement with the HBCU community, paving the way for future leaders in journalism.

The Altrusa Club of Wenatchee Scholarship supports female graduates of Wenatchee Valley College pursuing further education. Funded by the Community Foundation of NCW, this scholarship aims to empower women through financial assistance based on need and academic merit. Eligible recipients must maintain a minimum GPA of 2.0 and demonstrate commitment to their educational goals. This initiative reflects the club's dedication to promoting women's education and ensuring their successful transition to higher learning institutions.

The Liz Colantuono & Mark Sanz Endowment Scholarship, offered by the United Negro College Fund, provides need-based financial support to Native American students and adult refugees enrolled or accepted at accredited U.S. four-year institutions. With a focus on those facing financial challenges, this scholarship aims to empower students who demonstrate a commitment to education in STEM, education, accounting, or journalism, thereby fostering future leaders in these fields.

The Hilda M. Hill Memorial Vocational/Technical Scholarship, offered by the Four County Community Foundation, supports seniors and recent graduates from Capac, Almont, and Imlay City pursuing vocational or technical programs. Eligible students must have a minimum GPA of 1.50 and can receive up to two awards, with financial need considered. Award recipients will be celebrated at the Foundation's Scholarship Celebration in May, highlighting the Foundation's commitment to enhancing educational opportunities in the community.

The MI Association of Professional Insurance Agents Scholarship, offered by the Four County Community Foundation, supports seniors and recent graduates in Michigan planning to pursue a major in Risk Management/Insurance. Award recipients will be honored at the Foundation's Scholarship Celebration in May and announced at local high school events. Up to four awards are available, and students must submit an essay for consideration, reinforcing the Foundation's commitment to education and community development.

The Pete and Mary Houck Scholarship, established by the Community Foundation of North Central Washington, honors the legacy of Pete and Mary Houck, long-time residents of Wenatchee Valley. This scholarship aims to support local students pursuing healthcare degrees, reflecting the couple's commitment to education and community. Eligible applicants must be residents of Chelan or Douglas County and plan to attend accredited programs in healthcare-related fields, ensuring a brighter future for the community.