Best Large Grants for Nonprofit Organizations in South Carolina

The Ruth Danley and William Enoch Moore Charitable Fund Grant is a private foundation based in Pittsburgh, established in 1992. It focuses on philanthropy, specifically supporting K-12 education for Native American children living on reservations. The foundation directs its grants primarily to regions preferred by donors, including several states in the Northeast and Midwest, aiming to improve educational opportunities and foster community development in underserved populations.

The J.M.K. Innovation Prize, awarded by The J.M. Kaplan Fund, supports early-stage social innovators tackling critical issues in environment, heritage conservation, and social justice. With up to $175,000 in funding and tailored support over three years, it empowers organizations to pilot transformative solutions. The Prize fosters collaboration among awardees, providing resources and mentorship to enhance their impact. Open to both non-profit and mission-driven for-profit entities, it addresses the funding gap for innovative, high-potential projects.

About Us

The Community Foundation San Luis Obispo County is a resource for local charitable giving. Created by and for the people of San Luis Obispo County, The Community Foundation is an enduring source of charitable funds to meet the changing needs and interests of the region. We envision San Luis Obispo County as an inclusive haven where everyone, regardless of background, feels free to fully participate. In collaboration with our community partners and donors, we seek to foster a safe, respectful environment with ample opportunity for all to reach their potential and contribute to the success of our community. We invite you to join us in celebrating diversity, making sure all of our neighbors feel seen, and free from dehumanizing rhetoric and violence, as we shape a future where all residents can flourish. 

2025-2026 Scholarship Applications

Big dreams start here! With support from generous individuals, families, and businesses, the Community Foundation offers scholarships that help San Luis Obispo County students reach new heights in their education and careers.

Alan D. Stephenson Scholarship

The Alan D. Stephenson Scholarship was established to support promising LGBTQIA+ students to achieve their academic potential.

Community Foundation of Northwest Missouri

The Community Foundation of Northwest Missouri Inc. was established in 2009 as a 501(c)3 public charity to help donors support their favorite charities while receiving maximum tax advantage.

We serve as a vehicle for charitable giving, helping donors give to the causes they care about. Donor gifts will strengthen nonprofits increasing programs and services. Individuals and organizations are encouraged to establish a fund with us. 

St Joseph School District Foundation Midland Empire Safety Association Scholarship

This fund was established by the Midland Empire Safety Association to provide academic scholarships to students pursuing a degree in occupational safety and/or health, industrial hygiene, environmental safety, industrial fire prevention, risk management and occupational medicine.

Guidelines:

Scholarship recipient is chosen by The Community Foundation of Northwest Missouri’s Finance/Grant Committee. Scholarships will be awarded on a one-time basis and disbursed in August.

Amount:

Minimum of $500.00 to be paid at the start of the Fall semester.

The St. Baldrick’s Foundation Summer Fellowship Award provides funding for undergraduate, graduate, or medical students to gain hands-on experience in pediatric oncology. With a stipend of $5,000 awarded to the mentor's institution, this fellowship supports the next generation of researchers dedicated to finding cures for childhood cancers. Since its inception, the foundation has mobilized volunteers through various fundraising events, fostering a community committed to transforming lives and advancing cancer research.

The St. Baldrick's Foundation Scholar (Career Development) Award supports early-career researchers dedicated to childhood cancer research. This three-year award, which can be extended for two additional years based on progress, provides up to $110,000 per year. Founded in 2000, the foundation has mobilized volunteers worldwide to raise funds through head-shaving events and various activities, all aimed at finding cures and improving survivors' lives.

The Numotion Foundation Grants aim to enhance the lives of individuals with mobility disabilities by supporting IRS-designated 501(c)(3) nonprofit organizations. By fostering partnerships with various charities, including national and local organizations, the foundation raises awareness and funds for necessary research and support services. Contributions are made for each new wheelchair sold, ensuring a coordinated approach to charitable giving while prioritizing programs that specifically assist those with mobility-related challenges.

The NCCIH Natural Product Early Phase Clinical Trial Phased Innovation Award supports investigator-initiated clinical trials of natural products, including botanicals and dietary supplements. This funding opportunity aims to validate the pharmacokinetics and bioavailability of these products over three years in a phased approach. Successful trials will provide crucial data for further development and clinical application, emphasizing the importance of scientifically driven research in natural product efficacy.

The NCCIH Natural Product Early Phase Clinical Trial Award (R33 Clinical Trial Required) promotes innovative clinical trials on natural products, such as botanicals and dietary supplements. This funding opportunity supports studies that demonstrate significant scientific rationale and preliminary evidence for efficacy. Applications can explore various delivery methods and combinations with existing treatments to enhance outcomes. Funding is available for up to three years, aimed at bridging basic science discoveries into practical clinical applications.

The NCCIH Natural Product Mid Phase Clinical Trial (R01 Clinical Trial Required) invites applications for mid-phase clinical trials involving natural products like botanicals and dietary supplements. The goal is to advance clinical testing through robust preliminary data, ensuring these products demonstrate measurable impacts on target engagement. Submission deadlines span from March 2024 to October 2026. Applications must focus on optimizing doses and identifying patient responders to inform future efficacy trials, aligning with NCCIH's research priorities.

Community Foundation of the Fox River Valley

The Community Foundation of the Fox River Valley is a collection of individual funds and resources given by local citizens to enhance and support the quality of life in the Fox River Valley of Illinois.

We are a tax-exempt public charity that allows individuals, businesses, and non-profit organizations to establish permanent endowments and temporary funds within the confines of one large foundation.

Foundation funds are used to provide grants to non-profit organizations and scholarships to area students. The Foundation also hosts a Youth Engagement in Philanthropy (YEP) program, which helps high school students learn more about philanthropy and empowers them to make a difference in the community.

The Community Foundation of the Fox River Valley serves the City of Aurora, Kane County, and Kendall County within the State of Illinois.

Helen Schlicht McGeachy & Arthur C. Schlicht Scholarship Endowment Fund

This fund provides scholarships to students graduating from Aurora Central, Aurora Christian, East Aurora, Marmion Academy, Rosary or West Aurora High School.

Students entering the field of education, engineering, science, medicine or nursing are eligible to apply for these awards.

This fund was established by Arthur C. Schlicht (1936-2020) in memory of his mother Helen Schlicht McGeachy.

Helen McGeachy (1910-1994) was a graduate of East Aurora High School. An outstanding typist and secretary, she ultimately became secretary to the presidents of CA&E Railway and Walker Process Equipment of Aurora. Arthur Schlicht was vice-president/national sales manager at Walker Process Equipment. He earned a degree in chemical engineering from the Illinois Institute of Technology.

This fund was created in 1994 and established as an endowment in 1995.

The monetary value of each scholarship award varies depending upon the amount available in each individual scholarship fund. The most common scholarship award amount is $1,000 for a single year. Scholarships are designated as non-renewable one-year awards or renewable multi-year awards depending upon the scholarship fund criteria, as established by the donor of the scholarship fund.

Community Foundation of the Fox River Valley

The Community Foundation of the Fox River Valley is a collection of individual funds and resources given by local citizens to enhance and support the quality of life in the Fox River Valley of Illinois.

We are a tax-exempt public charity that allows individuals, businesses, and non-profit organizations to establish permanent endowments and temporary funds within the confines of one large foundation.

Foundation funds are used to provide grants to non-profit organizations and scholarships to area students. The Foundation also hosts a Youth Engagement in Philanthropy (YEP) program, which helps high school students learn more about philanthropy and empowers them to make a difference in the community.

The Community Foundation of the Fox River Valley serves the City of Aurora, Kane County, and Kendall County within the State of Illinois.

Kayla’s Hope Foundation Scholarship Fund

Kayla’s Hope Scholarship Fund was created by Hans, Ruthie and Hannah Lehmann of Saint Charles, IL to honor the life of their beautiful daughter and sister, Kayla Brooke Lehmann (April 5, 2003- April 7, 2018). Scholarships from the fund are awarded to graduates of St. Charles East High School, St. Charles North High School, Geneva High School and Batavia High School who will continue their education studying Music, Literature, psychiatry or psychology.   

The monetary value of each scholarship award varies depending upon the amount available in each individual scholarship fund. The most common scholarship award amount is $1,000 for a single year. Scholarships are designated as non-renewable one-year awards or renewable multi-year awards depending upon the scholarship fund criteria, as established by the donor of the scholarship fund.

The Undergraduate Development Program Advisor Travel Award, hosted by the Society of Toxicology, enables faculty advisors to attend the Undergraduate Development Program from March 21-23, 2026. This initiative aims to familiarize advisors with toxicology and encourage them to guide students toward careers in biomedical sciences. Recipients of the award will participate in educational sessions, networking opportunities, and receive support for travel-related expenses, fostering diversity and innovation within the field.

Community Foundation of the Fox River Valley

The Community Foundation of the Fox River Valley is a collection of individual funds and resources given by local citizens to enhance and support the quality of life in the Fox River Valley of Illinois.

We are a tax-exempt public charity that allows individuals, businesses, and non-profit organizations to establish permanent endowments and temporary funds within the confines of one large foundation.

Foundation funds are used to provide grants to non-profit organizations and scholarships to area students. The Foundation also hosts a Youth Engagement in Philanthropy (YEP) program, which helps high school students learn more about philanthropy and empowers them to make a difference in the community.

The Community Foundation of the Fox River Valley serves the City of Aurora, Kane County, and Kendall County within the State of Illinois.

Mary Virginia Hughes and Wesley C. Hughes Scholarship Endowment Fund

This fund was created upon receipt of bequests from the estates of Mary Virginia Hughes and Wesley C. Hughes.

Their parents, Wayne and Sadie Hughes, owned and operated a farm in Newark.

Mary Hughes lived and worked on the family farm her entire life and was a member of the Millbrook United Methodist Church.

It was important to both Mary and Wesley to use their legacies to support the education of local students.

Scholarships from the fund are available to students graduating from a high school located in Kendall County for attendance at an accredited college or university.

These awards are reserved for students pursuing a major in the field of agriculture.

The monetary value of each scholarship award varies depending upon the amount available in each individual scholarship fund. The most common scholarship award amount is $1,000 for a single year. Scholarships are designated as non-renewable one-year awards or renewable multi-year awards depending upon the scholarship fund criteria, as established by the donor of the scholarship fund.

Community Foundation of the Fox River Valley

The Community Foundation of the Fox River Valley is a collection of individual funds and resources given by local citizens to enhance and support the quality of life in the Fox River Valley of Illinois.

We are a tax-exempt public charity that allows individuals, businesses, and non-profit organizations to establish permanent endowments and temporary funds within the confines of one large foundation.

Foundation funds are used to provide grants to non-profit organizations and scholarships to area students. The Foundation also hosts a Youth Engagement in Philanthropy (YEP) program, which helps high school students learn more about philanthropy and empowers them to make a difference in the community.

The Community Foundation of the Fox River Valley serves the City of Aurora, Kane County, and Kendall County within the State of Illinois.

Ralph & Alice Kramp Scholarship Endowment Fund in Memory of Randy Kramp

The Ralph and Alice Kramp Scholarship Endowment Fund in Memory of Randy Kramp was created in 2010.

Randy Kramp, a lifelong Auroran, was forty years old when he was diagnosed with pancreatic cancer. After a three-year battle, he died in June of 2010 of complications from the treatment. Mr. Kramp joined Cub Scouts as soon as he reached the age of eligibility and that began a lifelong enjoyment and commitment to the values of scouting. After he achieved the rank of Eagle Scout, he assumed the role of adult leadership as a Wood Badger. He remained active in scouting his entire life.

Scholarships from this fund are available to current or former Boy Scouts in the Fox Valley who are pursuing a higher education toward a career in the field of fire service or emergency medical service.

The monetary value of each scholarship award varies depending upon the amount available in each individual scholarship fund. The most common scholarship award amount is $1,000 for a single year. Scholarships are designated as non-renewable one-year awards or renewable multi-year awards depending upon the scholarship fund criteria, as established by the donor of the scholarship fund.

The American Geophysical Union Jerome M. Paros Scholarship Award supports graduate students pursuing geophysical instrumentation and precise field measurements in seismology, atmospheric sciences, or ocean sciences. Established by Jerome M. Paros, the scholarship awards up to $5,000 to three students annually, fostering talent in this critical field. Eligibility includes being a graduate student at an accredited institution, with a focus on geophysical measurements. AGU student members are encouraged to apply.

The June Bacon-Bercey Scholarship in Atmospheric Sciences for Women supports women pursuing careers in atmospheric sciences and meteorology. Established in 1978 and reintroduced in 2021, it offers a $1,000 scholarship, mentorship opportunities, and networking through AccuWeather. Eligible applicants must identify as women and belong to underrepresented groups in STEM, including Black, Indigenous, and LGBTQ+ individuals, and must be graduate or undergraduate students in relevant programs.

Scholarships support aspiring college students who hold the promise of tomorrow’s progress.

Together, our competitive grants and scholarships help our region rise thanks to the vision and generosity of our donors.

The Congressman Mark Foley Scholarship for Nursing Education Fund

Must be enrolled in a professional nursing program.

The MCSF Career & Technical Education Scholarship supports children of Marines pursuing non-degree certificate programs. It offers financial assistance to eligible applicants based on need, helping cover tuition, fees, and associated educational costs. With a minimum GPA requirement of 2.00 and a family income cap of $123,000, this scholarship ensures that all qualifying students have access to vocational training at accredited institutions. Applications are accepted year-round, providing flexibility for students.

The Community Foundation of the Rappahannock River Region

The Community Foundation is a devoted advocate for the vitality and well-being of the Rappahannock River Region. We are a 501(c)(3) nonprofit that manages and distributes charitable giving in the counties of Stafford, Spotsylvania, King George, and Caroline, and the City of Fredericksburg.

Scholarships

One of The Community Foundation’s strategies for preserving and growing the quality of life in our region is supporting higher education for area students. Generous individuals and families, companies and organizations establish endowed scholarship funds and the proceeds from these funds benefit deserving students. Donors work with foundation staff to determine appropriate criteria for each fund. The Community Foundation currently administers more than fifty scholarship funds.

The Walton Mahon Scholarship Fund

This scholarship fund was created in March 1991 by Union Bank and Trust in recognition of the many years of devoted service which Mr. Walton Mahon gave to the bank. Mr. Mahon worked for Union Bank and Trust for 42 years, serving as President for 25 of those years. He continued to lead the bank after his retirement for another 9 years as a member of the Board of Directors, serving the bank for over 50 years in all.

With their gift, Union Bank and Trust wished to support the college or university education of a Caroline County student or students wishing to pursue a career in business. 

The Community Foundation of the Rappahannock River Region

The Community Foundation is a devoted advocate for the vitality and well-being of the Rappahannock River Region. We are a 501(c)(3) nonprofit that manages and distributes charitable giving in the counties of Stafford, Spotsylvania, King George, and Caroline, and the City of Fredericksburg.

Scholarships

One of The Community Foundation’s strategies for preserving and growing the quality of life in our region is supporting higher education for area students. Generous individuals and families, companies and organizations establish endowed scholarship funds and the proceeds from these funds benefit deserving students. Donors work with foundation staff to determine appropriate criteria for each fund. The Community Foundation currently administers more than fifty scholarship funds.

The William and Susanna Botts Scholarship for Immigrants

The Botts family has been supportive of and advocates for the immigrant community for many years. Susanna taught English as a Second Language in Stafford County schools for eleven years until her retirement in 2010. Since that time, she has continued to work part-time with county ESL students; in addition, she has worked with immigrant families in their homes. Bill provided legal assistance to lawfully represent immigrants in civil matters for many of his 40 years as a legal aid attorney. In 2002, while Executive Director of Rappahannock Legal Services (now Legal Aid Works), he encouraged the Board of Directors to give up all federal funding for the legal aid program so that the organization could represent undocumented immigrants as well. Since 2016, he has served as a volunteer attorney for Baptist-based LUCHA Ministries Immigration Legal Services.

Bill and Susanna have also worked together through Catholic Charities to assist endangered children to come to the United States as refugees from Guatemala, Honduras, and El Salvador. They have worked through their church, Fredericksburg United Methodist, tutoring ESL students at Hugh Mercer Elementary School. All of their efforts have been informed and inspired by their experiences on over a dozen church mission trips to Central America and Mexico.

The Botts believe supporting the educational dreams of immigrant youth will serve not only the immigrant community, but also the community at large. The William and Susanna Botts Scholarship for Immigrants will award at least two annual scholarships of $1,000 to support high achieving and or/highly motivated immigrants or refugees in our community. 

About Legacy Foundation

Legacy Foundation is the community foundation for Lake County, Indiana. We connect people, knowledge, and funding to build an equitable, accessible, and inclusive Lake County, now and for generations to come.

Legacy Foundation is supported by a broad base of individuals, families, and businesses connected by the desire to improve Lake County, Indiana. With a growing portfolio of over 300 funds and approximately $80 million in assets, Legacy Foundation is a trusted source for philanthropic giving in the region.

For over 30 years, Legacy Foundation has been empowering people, providing strategic leadership, and impactful philanthropic support to create an equitable Lake County where all people thrive.

Mission Statement

Transforming Lake County by providing strategic leadership and impactful philanthropic support to ensure equitable opportunity for all communities that we serve.

Vision Statement

Create an equitable Lake County where all people thrive.

Scott Campion Scholarship for Special Education Teacher

Use the chart below to see which scholarships are the best fit for you! You must complete the Legacy Universal Application to apply.

Scholarship eligibility requires students to attend an accredited 2 or 4 year public or private institution of higher learning. All scholarships are for full-time students, unless otherwise noted. Renewable awards are for 4 years of undergraduate study and cannot be used for post graduate coursework; all awards are paid directly to the school or may be used for book reimbursement.

Scholarships support aspiring college students who hold the promise of tomorrow’s progress.

Together, our competitive grants and scholarships help our region rise thanks to the vision and generosity of our donors.

Frank and Marie Cleary Memorial Scholarship Fund

• Must be a parishioner of St. Mary’s Church in Pahokee.
• Demonstrate financial need.

Scholarships support aspiring college students who hold the promise of tomorrow’s progress.Together, our competitive grants and scholarships help our region rise thanks to the vision and generosity of our donors.Frank P. Husvar Memorial Scholarship FundFrank was a determined man. During a 21-year Army career, he saw action in WWII and Korea, and rose to the rank of 1st Sergeant. When he retired at a comparatively young age, he was far from ready for a life of leisure. He became a math and science teacher. When throat cancer forced Frank to have a laryngectomy, he refused to let the problem get him down. He learned esophageal speech and returned to his middle school students. Later, he went to the Mayo Clinic for training to become a certified speech teacher, resolving to help others with similar challenges.Frank was very interested in children and education,” Martha notes. “The scholarship fund is a way to carry on his name and to honor him.”

• Pursuing a degree in education in math or speech pathology.
• Student should be participating in extracurricular activities common to that field of study.

Scholarships support aspiring college students who hold the promise of tomorrow’s progress.

Together, our competitive grants and scholarships help our region rise thanks to the vision and generosity of our donors.

The Sampson Scholarship Fund

This scholarship is for a Year 3 or Year 4 veterinary school student or resident committed to Zoological or Wildlife Medicine.

The Craig Zadan Pathway for Equity in the Arts Grant aims to enhance high school theatre programs in underserved communities. By providing $10,000 grants, this initiative fosters collaboration between students and industry professionals, while promoting performances that address diverse perspectives. The grant encourages schools to select plays that spark important conversations, ensuring inclusivity and representation in the arts. Ultimately, it seeks to inspire students and open doors to future careers in theatre.

Stark Community Foundation is one of the area’s major sources of college scholarship support— thanks to the generosity of caring individuals, families and businesses that have created scholarship funds.

The Foundation currently manages more than 100 scholarship funds that support hundreds of deserving students each year from Stark and Carroll counties. In 2025, more than $1,000,000 was awarded to local students to help them achieve their educational dreams.

The Melvin L. and Frances E. Tolson Scholarship Trust Fund

The Melvin L. and Frances E. Tolson Scholarship Trust Fund was established to assist students who are residents of Carroll County, Ohio in furthering their education with interests in either aviation, art education or fine and performing arts who are enrolled or accepted at a college, university, technical, or vocational school.

Amount:

• Varies. Minimum $500.

Renewable:

• Yes