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Best Private Grants for Nonprofits in South Carolina

Find the perfect Private grants for nonprofits in South Carolina on Instrumentl. 9,000+ Private grants for nonprofits in South Carolina in the United States.

9,000+

Available grants

$2.62B

Total funding

$5K

Median grant

9,000+ grants
$2.62B total
$5K median

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9,457 Results based on applied filters

DIF x Tech Fund

Borealis Philanthropy
Private
American Samoa, Guam +4 more
US $25,000 - US $70,000

About Borealis Philanthropy

Borealis Philanthropy is a philanthropic social justice intermediary that works to resource grassroots leaders and social justice movements for transformative change. We help funders expand their reach and strengthen their impact through donor collaboratives that support a variety of issues, communities, and movements. Borealis is home to nine donor collaboratives, including the Disability Inclusion Fund and Disability x Tech.

DIF x Tech Fund

For the Disability Inclusion Fund at Borealis, part of our efforts for disability rights and justice includes the ways disability and technology are working towards shared goals in our movements. The DIF x Tech initiative, supported by the Ford Foundation’s Technology & Society Program and the MacArthur Foundation’s Technology in the Public Interest, invites proposals that are working to bring about transformational change at the intersections of disability, justice, and technology

About the Disability Inclusion Fund and DIF x Tech

The Disability Inclusion Fund (DIF) supports U.S.-based groups run by and for people with disabilities to lead transformational change. The Fund is supported by donors including the Presidents’ Council on Disability Inclusion in Philanthropy, which is comprised of foundation presidents who are committed to disability inclusion as part of improving diversity, equity, and inclusion within philanthropy.

Part of the efforts of disability rights and justice includes the ways disability and technology are working towards shared goals in our movements. This newly launched initiative is housed at the Disability Inclusion Fund (DIF) and supported by Ford Foundation’s Technology & Society Program and the MacArthur Foundation’s Technology in the Public Interest. 

DIF x Tech Fund Values

All Disability x Tech award decisions will align with the DIF guiding values. The DIF guiding values are:

  • Participation: Movement funding accountable to the disability rights movement. Those impacted by injustice/exclusion should be involved in strategies to advance justice/inclusion.
  • Intersectionality: Acknowledging that disabled people have multiple and intersecting social and political identities that can influence their ability to have access and inclusion including race, gender identity, class, sexual orientation.
  • Radical inclusion: Deeply committed to removing barriers and ensuring access so that those most affected by intersecting identities can participate, valuing lived experience.
  • Leadership of those most impacted by ableism: Emphasis is given to organizations led by people subject to systemic bias and impacted by underrepresentation, particularly disabled people of color, queer, gender nonconforming and women with disabilities.
  • Cross-movement solidarity: Intentional focus on collaboration and bridge- building amongst disability justice activists and across movements.
  • Sustainability: Resources and tools that support the growth of grassroots disabled-led organizations, and expand operational capacities for ongoing movement building. 

What we fund

We invite proposals that are at the nexus of technology, disability rights and justice. This opportunity may be a good fit for your organization, if you are doing work in any of these areas below:

  • Disabled people sharing technical skills and knowledge with others in the community.
  • Disabled people leading policy, rights, and disability justice activism work related to tech. 
  • Disabled people participate in all stages of the design and development of new tech that will enrich lives of people with disabilities.
  • Enabling collective and equitable access to digital infrastructure. 
  • Expanding the participation, leadership, and thought partnership of overlooked and under-resourced people with disabilities in all areas of the technology sector.
  • Partnerships between disability-focused engineering design labs and maker spaces within schools, centers for independent living, or local nonprofit organizations.
  • Permissible Policy Work:
    • We may support nonpartisan policy education and advocacy related to disability and technology. Any lobbying must remain within applicable 501(c)(3) limits and Borealis grant restrictions.

Technology Access & Digital Literacy Disability Rights & Justice

The Community Heart & Soul Seed Grant Program

Community Heart & Soul
Private
American Samoa, Guam +4 more
US $10,000
The Community Heart & Soul Seed Grant Program offers $10,000 in startup funding for community-driven groups in small towns to adopt the Community Heart & Soul model. Applications are accepted until 11:59 p.m. EST on the last business day of each month, with funding decisions made the following month. This initiative aims to empower residents to engage in local development and foster community connections.
Community Development & Revitalization Rural Development

Toward Translation of Nanotechnology Cancer Interventions (TTNCI; R01 Clinical Trial Not Allowed)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $1,900,000
The National Cancer Institute (NCI) invites applications for the Toward Translation of Nanotechnology Cancer Interventions (TTNCI) program. This funding opportunity focuses on advanced pre-clinical research aimed at developing nanotechnology-based cancer diagnostics and therapeutics. TTNCI awards will support the maturation of innovative nanomedicines using nanoparticles and nano-devices, enhancing cancer treatment efficacy. Successful projects will progress towards further NCI translational programs, such as the NExT initiative.
Cancer / Oncology Nanomaterials & Nanotechnology

Charles Lathrop Parsons Award

American Chemical Society
Association/Society
United States
Up to US $7,500
The Charles Lathrop Parsons Award, presented by the American Chemical Society, honors exceptional public service by ACS members. This prestigious award includes a $5,000 monetary prize and a certificate. Up to $2,500 can be reimbursed for travel expenses related to the award ceremony. It is awarded every two years, although the interval may be shortened at the discretion of the ACS Board for deserving nominees. All eligible members are encouraged to apply.
Chemistry Volunteerism & Philanthropy

Career Awards at the Scientific Interface

Burroughs Wellcome Fund
Private
Canada, United States
US $560,000
The Burroughs Wellcome Fund's Career Awards at the Scientific Interface provide $560,000 over five years to support early-career researchers transitioning from physical and computational sciences to biological sciences. Launched in 1999, these awards aim to enhance academic research careers for U.S. and Canadian citizens, permanent residents, and temporary residents, fostering a diverse and innovative scientific workforce essential for advancing human health.
Science Biology Mathematics +3 more

Healthcare Auxillary Scholarship

Northwest Connecticut Community Foundation
Private
United States
US $2,500
The Healthcare Auxiliary Scholarship, offered by the Northwest Connecticut Community Foundation, provides two scholarships of $2,500 each for students pursuing careers in healthcare. Eligible applicants must reside in Canaan, Cornwall, Kent, North Canaan, Salisbury, or Sharon. Preference is given to those who actively volunteer and engage with their community. This initiative aims to support local students in achieving their academic and professional goals in the healthcare sector.
Medical Education & Professional Training Education - Higher Education Community Services

Teacher Professional Development Grants (6-8)

National Council of Teachers of Mathematics
Association/Society
United States
Up to US $3,000
The Teacher Professional Development Grants (6-8), offered by the National Council of Teachers of Mathematics, aim to enhance the teaching skills of classroom teachers in grades 6-8. This grant supports professional development initiatives that focus on improving mathematics instruction. Eligible applicants must have at least three years of teaching experience and spend a majority of their time teaching in the classroom. The program encourages high-quality mathematics education for all students.
Mathematics Teacher Development & Training STEM / STEAM Education

Ignite Leadership Program

Society of Women Engineers
Private
United States
Unspecified amount
The Ignite Leadership Program, organized by the Society of Women Engineers, empowers early-career women engineers to enhance their leadership skills. Participants will assess their strengths, identify growth opportunities, and create personalized leadership development plans. This virtual program runs from September to December 2025, featuring group discussions and peer coaching. Its goal is to broaden the leadership pipeline within SWE, preparing the next generation of women leaders in engineering and technology.
Engineering Women & Girl Services Teacher Development & Training

Emerging Teacher-Leaders in Elementary School Mathematics Grants

National Council of Teachers of Mathematics
Association/Society
United States
Up to US $6,000
The Emerging Teacher-Leaders in Elementary School Mathematics Grants, provided by the National Council of Teachers of Mathematics, aim to enhance the mathematics content knowledge of dedicated elementary school teachers. This initiative focuses on developing teacher-leaders who will deliver ongoing professional development to fellow educators, thereby strengthening instructional practices. Eligible applicants include experienced classroom teachers or full-time mathematics coaches committed to improving mathematics education. The program supports projects that align with enhancing the mathematics learning environment.
Teacher Development & Training Mathematics STEM / STEAM Education

Cottrell IMPACT Award

Research Corporation
Private
Canada, United States
US $5,000
The Cottrell IMPACT Award recognizes the significant contributions of Cottrell Scholars and Holland Award recipients in advancing science through leadership and service. It encourages excellence in academic leadership while raising the profile of awardees nationally. The award includes a $5,000 cash prize and highlights recipients at the Cottrell Scholar Conference and in professional journals, fostering a community of innovative researchers committed to impactful science.
Science Chemistry Physics +1 more

Designing Innovative Lessons and Activities for Mathematics Teaching (K–8)

National Council of Teachers of Mathematics
Association/Society
United States
Up to US $15,000
The Designing Innovative Lessons and Activities for Mathematics Teaching grant, sponsored by the National Council of Teachers of Mathematics, aims to enhance K–8 mathematics education through collaborative writing and material development. With an initial award of $5,000 and potential for renewal up to $15,000, this grant encourages teams of educators to create engaging, non-routine lessons that focus on key mathematical themes. Eligible applicants include leadership teams from multiple schools, fostering innovation in teaching practices.
Teacher Development & Training Mathematics STEM / STEAM Education

NCI Pathway to Independence Award for Early-Stage Postdoctoral Researchers (K99/R00 - Independent Basic Experimental Studies with Humans Required)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NCI Pathway to Independence Award (K99/R00) aims to support early-stage postdoctoral researchers transitioning to independent faculty positions. This initiative focuses on talented individuals with doctoral degrees in research or clinical fields, providing essential NCI funding during this key career juncture. Researchers engaged in cancer control, prevention, and data sciences are encouraged to apply for this opportunity, which emphasizes experimental studies with human participants, thus aligning with NIH's clinical trial definitions.
Biology Science Medical Education & Professional Training +1 more

Cottrell STAR Award

Research Corporation
Private
Canada, United States
US $5,000
The Cottrell STAR Award recognizes exceptional research and educational achievements of Cottrell Scholars and Holland Award recipients. It aims to enhance science education at U.S. and Canadian universities, promoting the Cottrell Scholars' national profile. The award includes a $5,000 cash prize, with applications initiated through nominations. Highlighted at the summer Cottrell Scholar Conference, the award supports a vibrant community of early career faculty committed to innovative research and teaching in the physical sciences.
Science Chemistry Physics +1 more

Level 1 Rural Outreach Grant

National Association Of Realtors
Private
American Samoa, Guam +4 more
Up to US $3,000
The Level 1 Rural Outreach Grant, offered by the National Association of Realtors, aims to enhance REALTORS®' understanding of rural issues. With a maximum award of $3,000, this grant is available once per calendar year to associations. It supports educational efforts and promotes smart growth and diversity in rural communities. Grant recipients are required to complete an evaluation form for the funded activities, ensuring accountability and effectiveness in addressing rural challenges.
Community Services Rural Development

Pakideh/Khaghany Endowed Scholarship

Community Foundation of Monroe County
Private
United States
Unspecified amount
The Pakideh/Khaghany Endowed Scholarship, offered by the Community Foundation of Monroe County, supports local seniors pursuing degrees in science-related fields. This initiative aims to foster educational growth and career readiness, ensuring that Monroe County students have access to the resources they need to succeed in their academic journeys. With a commitment to community development, the scholarship highlights the foundation's dedication to enhancing educational opportunities for future generations.
Education - Higher Education STEM / STEAM Education Science

Beverly E. Falconbury Memorial Scholarship

Marshall County Community Foundation Inc
Private
United States
Unspecified amount

Connecting Passion to Purpose

Marshall County Community Foundation is a public charity where local roots help great ideas take flight. We are community-minded partners and trusted investors. We help shape the vision for Marshall County. Our passion is to connect caring people with opportunities to make an impact.

Our mission is to serve all of Marshall county — its people and its future — by growing and managing endowment funding and fostering philanthropy.

Investing in the Scholars of 
Marshall County

Marshall County Community Foundation administers a number of scholarships, from traditional awards for graduating seniors to those geared towards current students, professionals, and other special circumstances.

Each scholarship has its own application guidelines, deadlines, and application process, so please be sure to read the instructions of the scholarship you’re applying for carefully.

All Marshall County Scholarships

We administer a number of scholarships, which range from the traditional academic and athletic awards to corporate and special circumstances offerings. These scholarships are open to all residents of Marshall County, as long as other requirements are met.

Applying for a scholarship is free, so we invite you to spend some time finding opportunities for which you are a good fit. You can learn more about each scholarship by clicking on each of the below scholarship titles.

Scholarship applicants must intend to major in mathematics at an accredited two-year or four-year public or private institution of higher learning.

Mathematics Education - Higher Education STEM / STEAM Education

Eldon D. Shafer Memorial Scholarship

Marshall County Community Foundation Inc
Private
United States
Unspecified amount
The Eldon D. Shafer Memorial Scholarship, managed by the Marshall County Community Foundation, supports graduating seniors from various local high schools who plan to major in mathematics at accredited institutions. This scholarship aims to foster educational opportunities for students in Marshall County, encouraging them to pursue their academic passions without financial burden. Interested applicants should carefully review specific application guidelines and eligibility requirements to ensure a successful submission.
Education - Higher Education Mathematics STEM / STEAM Education

Robert C. Seamans, Jr. Fellowship in Science, Technology, and Public Policy

Harvard Kennedy School (HKS) - Harvard University
Association/Society
United States
Unspecified amount
The Robert C. Seamans, Jr. Fellowship in Science, Technology, and Public Policy at Harvard Kennedy School supports students excelling in research and management at the intersection of technology and public policy. This fellowship fosters future leadership in these critical areas, ensuring a commitment to addressing pressing public challenges. Applicants from diverse backgrounds are encouraged, as the program is designed to promote inclusivity and recognizes the importance of varied perspectives in policy-making.
Public Policy Education - Higher Education Science

Charles Edison Fund Fellowship

Harvard Kennedy School (HKS) - Harvard University
Association/Society
United States
Unspecified amount
The Charles Edison Fund Fellowship at Harvard Kennedy School supports students aiming to enhance the impact of the Science, Technology, and Public Policy Program. This fellowship targets those committed to addressing significant public issues through innovative solutions. Ideal for both U.S. and international applicants, it emphasizes merit and financial need, aligning with Harvard's mission to foster public policy leadership and promote a just and sustainable society.
Public Policy Education - Higher Education Science

Cornerstone: Learning for Living- Implementation Grants

The Teagle Foundation Incorporated
Private
United States
Up to US $350,000
The Teagle Foundation and the NEH are offering the Cornerstone: Learning for Living implementation grants to enhance the role of humanities in higher education. Aimed at revitalizing student engagement, the initiative supports diverse institutions in creating transformative curricula and fostering community. Grants of up to $350,000 over 24 months will fund faculty development, course redesign, and outreach efforts, ensuring sustainable humanities programs that benefit a wide array of students, particularly in STEM fields.
Education - Higher Education Humanities & Social Science Teacher Development & Training

Science of Science: Discovery, Communication, and Impact

National Science Foundation (NSF)
Federal Government
United States
Unspecified amount
The Science of Science: Discovery, Communication, and Impact (SoS:DCI) program fosters research that enhances the public value of scientific endeavors. It invites proposals that explore mechanisms of scientific discovery, improve understanding of communication outcomes, and assess societal benefits of science. Emphasizing interdisciplinary approaches, the program prioritizes proposals that broaden participation in science, engage diverse teams, and support America's leadership in global scientific innovation. The goal is to create impactful, evidence-based policies and advance the science of science.
Science Communications Science

Cornerstone: Learning for Living- Planning Grants

The Teagle Foundation Incorporated
Private
United States
Up to US $25,000
The Cornerstone: Learning for Living Planning Grants, sponsored by The Teagle Foundation and NEH, aim to revitalize humanities education in higher learning. With a focus on transformative texts and faculty engagement, the initiative encourages diverse institutions to innovate general education. Grants up to $25,000 support curriculum reform and professional development, fostering a sense of belonging and community among students while enhancing their analytical skills and cultural awareness.
Education - Higher Education Humanities & Social Science Teacher Development & Training

Surveillance and Case Control Study of Stillbirth and Birth Defects (SUCCSSBD)

Dept. of Health & Human Services: Centers for Disease Control & Prevention
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Surveillance and Case Control Study of Stillbirth and Birth Defects (SUCCSSBD) aims to enhance the quality of birth defects and stillbirth surveillance in the U.S. By modernizing data collection through electronic case reporting, the initiative seeks to improve data quality and timeliness. The study will focus on identifying risk factors for birth defects and stillbirths, addressing a significant public health issue that affects thousands of pregnancies annually. CDC funding will support three key components in this effort.
Genetic Conditions & Birth Defects Data Science & Digital Information Systems

Professor Emeritus John Edward Lillich Endowed Scholarship Program

United Negro College Fund Inc
Private
United States
US $4,400
The Professor Emeritus John Edward Lillich Endowed Scholarship Program, funded by the United Negro College Fund, aims to provide need-based scholarships to students majoring in engineering at HBCUs, with a preference for those attending North Carolina Agricultural and Technical State University (NCAT). This scholarship honors John Edward Lillich, a WWII veteran and advocate for women in engineering, supporting students in their pursuit of education and leadership roles.
Education - Higher Education Academic Scholarship Programs Engineering

Career Awards for Medical Scientists

Burroughs Wellcome Fund
Private
Canada, United States
US $700,000
The Career Awards for Medical Scientists (CAMS), established by the Burroughs Wellcome Fund, offers $700,000 over five years to support early career physician scientists transitioning to independence in academic biomedical research. This highly competitive program aims to enhance research innovation and public service by fostering a diverse scientific workforce. Proposals in basic biomedical, disease-oriented, or translational research, particularly those incorporating artificial intelligence or addressing climate change and human health, are encouraged.
Medical Education & Professional Training Science Health & Medicine +1 more

NIDA Avenir Program: Fundamental Mechanistic Research in Addiction Science

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $375,000
The NIDA Avenir Program aims to cultivate innovative leaders in addiction science by funding exceptional early stage investigators (ESIs) embarking on pioneering research. Launched in 2015, this initiative encourages high-risk, high-reward mechanistic studies related to Substance Use Disorders (SUDs) across diverse scientific domains. Applications from new investigators and those outside addiction research are welcomed, fostering interdisciplinary approaches that enhance understanding of SUD mechanisms. The program supports ESIs who may lack preliminary data but demonstrate potential for impactful contributions.
Genetics & Genomics Addiction & Substance Use Disorders Emerging Technology Development

Maier Foundation Scholarship

Communities Foundation of Texas
Private
United States
Up to US $5,000
The Maier Foundation Scholarship, established in 1953, aims to support students pursuing degrees in science, engineering, or medicine. Offering scholarships up to $5,000, it is open to applicants with a minimum GPA of 3.00 who reside in Collin or Denton County. Preference is given to first-generation college students. This initiative is part of the Communities Foundation of Texas's commitment to building thriving communities through education and opportunity.
Engineering Medical Education & Professional Training Academic Scholarship Programs

Private Grants for Nonprofits in South Carolina Highlights

Looking for private grants for nonprofits in South Carolina?


Read more about each grant below or start your 14-day free trial to see all private grants for nonprofits in South Carolina recommended for your specific programs.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Private Grants for Nonprofits in South Carolina

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

200+ Private grants for nonprofits in South Carolina grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

53 Private grants for nonprofits in South Carolina over $25K in average grant size

40 Private grants for nonprofits in South Carolina over $50K in average grant size

32 Private grants for nonprofits in South Carolina supporting general operating expenses

100+ Private grants for nonprofits in South Carolina supporting programs / projects

2,000+ Grants on Instrumentl focused on Art & Culture

500+ Grants on Instrumentl focused on Writing & Literature

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Private grants for Nonprofits in South Carolina?

Most grants are due in the first quarter.

Q1
28.9%
Q2
25.2%
Q3
24.8%
Q4
21.1%

Typical Funding Amounts

What's the typical grant amount funded for Private Grants for Nonprofits in South Carolina?

Grants are most commonly $15,000.

$500 $500 Min.
$15,000 $15 K Median
$535,356 $535.4 K Average
$40,331,313 $40.3 M Max.

Average Grant Size

What's the typical amount funded for South Carolina?

Grants are most commonly $74,506.

$74,506

Total Number of Grants

What's the total number of grants in Private Grants for Nonprofits in South Carolina year over year?

In 2024, funders in South Carolina awarded a total of 24,410 grants.

2022 21,855

2023 21,722

2024 24,410

Top Grant Focus Areas

Among all the Private Grants for Nonprofits in South Carolina given out in South Carolina, the most popular focus areas that receive funding are Education, Philanthropy, Voluntarism & Grantmaking Foundations, and Human Services.

1. Education

2. Philanthropy, Voluntarism & Grantmaking Foundations

3. Human Services

Funding Over Time

How is funding for Private Grants for Nonprofits in South Carolina changing over time?

Funding has increased by 22.06%.

2022 $1,534,818,247

2023 $1,485,349,233
-3.22%

2024 $1,813,067,383
22.06%

South Carolina Counties That Receive the Most Funding

How does grant funding vary by county?

Greenville County, Richland County, and Charleston County receive the most funding.

County Total Grant Funding in 2024
Greenville County $580,646,902
Richland County $413,417,941
Charleston County $355,724,083
Spartanburg County $325,246,878
Pickens County $159,596,081