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Best Private Grants for Nonprofits in South Carolina

Find the perfect Private grants for nonprofits in South Carolina on Instrumentl. 9,000+ Private grants for nonprofits in South Carolina in the United States.

9,000+

Available grants

$2.62B

Total funding

$5K

Median grant

9,000+ grants
$2.62B total
$5K median

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9,427 Results based on applied filters

Single Ventricle Research Fund (SVRF) - Career Development Track

Additional Ventures Foundation
Private
Countries
Up to US $300,000

Single Ventricle Research Fund (SVRF)

Our flagship funding program — the Single Ventricle Research Fund (SVRF) — is an annual research award program that supports foundational studies aimed at improving outcomes for individuals with single ventricle heart disease. By addressing the organ- and multi-organ-level complications and clinical sequelae that drive long-term morbidity and mortality, the SVRF seeks to close critical gaps in understanding and treatment, and accelerate progress toward better, more predictive, and preventative care.

In its sixth cycle, the SVRF welcomes foundational research that is directly relevant to improving outcomes for individuals with single ventricle heart disease.

What Fits

Through the SVRF, Additional Ventures aims to accelerate foundational research that will lead to improved care and new therapeutic opportunities grounded in a mechanistic understanding of single ventricle heart disease.

The 2027 SVRF welcomes research aligned with the focus areas and strategic topics described in the Additional Ventures’ 2026 Research Roadmap. We are particularly interested in proposals that seek to elucidate the mechanisms underlying, prevent, or reverse the interrelated organ- and multi-organ-level sequelae that contribute to long-term morbidity and mortality.

Eligible investigators include postdoctoral fellows or equivalents holding a mentored position. Collaborative proposals will not be accepted through this track.

Cardiovascular Diseases & Systems Heart Disease Preventative Healthcare

Scaling Pathways to Homeownership

Capital One Foundation
Corporate
American Samoa, Guam +4 more
US $200,000
  • Innovative: An approach that brings fresh thinking, tools, or models to homeownership in ways that challenge the status quo and demonstrate a disruptive, future-oriented vision with potential to inspire or shift broader field practice.
  • Impactful: A solution with meaningful potential to expand homeownership through knowledge and action, featuring clear and measurable progress indicators that demonstrate capacity to shift trajectories for low- and moderate-income households.
  • Bridge-Building: An initiative that effectively connects and unifies a wide range of stakeholders, fostering meaningful collaboration across sectors or perspectives. The strongest submissions will reflect strong community partnerships across the housing ecosystem.
  • Durable: A sustainable pathway that addresses root causes of homeownership barriers rather than just symptoms, with compelling evidence of potential to elicit robust support from broad private, philanthropic, and public funding sources over time.
Homeownership Equitable & Affordable Housing

Florence Merriam Bailey Award

American Ornithological Society
Association/Society
United States
US $1,500
The Florence Merriam Bailey Award, presented by the American Ornithological Society, honors outstanding articles published by early career members in AOS journals within the last two years. Awarded annually, it includes a $1,500 cash prize to the lead author. Papers recognized alternate between the journals 'Ornithology' and 'Ornithological Applications'. Nominees must adhere to high ethical standards as outlined in the AOS Code of Conduct.
Ornithology

AOS-Sponsored Student Memberships

American Ornithological Society
Association/Society
Countries
Unspecified amount
The AOS-Sponsored Student Memberships provide one year of free membership to students globally interested in ornithology. Awardees gain full access to AOS membership benefits and are encouraged to participate in various opportunities, including the annual meeting and travel grants. This initiative aims to foster the next generation of ornithologists by supporting their academic and professional growth while upholding high ethical standards aligned with the AOS Code of Conduct.
Ornithology

Jacquelin Goldman Congressional Fellowship

American Psychological Foundation Inc
Private
United States
US $75,000 - US $90,000
The Jacquelin Goldman Congressional Fellowship offers developmental and clinical psychologists a unique opportunity to gain public policy experience while enhancing the application of psychological knowledge in government. Funded by the American Psychological Foundation, this fellowship supports one fellow annually with a stipend of $75,000 to $90,000, along with health insurance reimbursement and professional development funds. Applicants must demonstrate expertise in child psychology and policy issues, and have strong communication skills.
Psychology Children’s Mental Health Health Policy & Advocacy +1 more

Katma Award

American Ornithological Society
Association/Society
United States
US $2,500
The Katma Award, established by the American Ornithological Society in 2003, honors innovative research that challenges existing theories in avian biology. This award encourages submissions of research articles, commentaries, or short communications published within the last two years. Nominees are expected to uphold high ethical standards, and the award includes a $2,500 prize and a certificate. Ideal submissions include papers authored by one or two researchers, with self-nominations also accepted.
Ornithology

Impact of Immunotherapies on CNS Outcomes in People with HIV: Potential Benefits, Challenges and Risks

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $2,000,000
The upcoming National Institute of Mental Health (NIMH) funding opportunity aims to explore the effects of HIV immunotherapies on central nervous system (CNS) outcomes. It seeks to identify mechanisms, benefits, and risks associated with these therapies, focusing on overcoming CNS-specific barriers. The initiative encourages collaborations to develop strategies for achieving sustained virologic remission and improving neurological outcomes for individuals with HIV, particularly targeting neurotoxicity and neuroinflammation.
HIV / AIDS

Indigo Hope Foundation: At-Risk Youth Development Grant

The Indigo Hope Foundation
Association/Society
Abbeville County, South Carolina, Anderson County, South Carolina +8 more
US $500 - US $100,000

Indigo Hope Foundation: At-Risk Youth Development Grant

Empowering programs that provide mentorship, education, life skills training, and opportunities for young people facing challenges.

Key Focus Areas:

  • Mentorship Programs
  • Educational Support
  • Life Skills Training
  • Career Development

Example Programs We Fund:

  • After-school tutoring and mentorship
  • Job readiness training
  • Leadership development
Workforce Preparation & Job Readiness Career / College Preparation Youth Development & Leadership

Long Cove Community Endowment Fund

Community Foundation of the Lowcountry
Private
Beaufort County, South Carolina, Jasper County, South Carolina
Unspecified amount
The Long Cove Community Endowment Fund focuses on supporting charitable initiatives in Beaufort and Jasper Counties, South Carolina. Its mission is to encourage giving among the Long Cove Club Members and provide grants for health, housing, hunger, and education. The fund prioritizes specific projects over general operating costs, ensuring continued support for local communities. Grants are evaluated semi-annually, and donor anonymity is maintained, fostering a sustainable and impactful charitable giving environment.
Health & Medicine Real Estate & Housing Food Access & Hunger +2 more

Microsoft Disability Scholarship

Seattle Foundation
Private
United States
US $5,000

Seattle Foundation is an agent of change, igniting powerful, rewarding philanthropy to make Greater Seattle a stronger, more vibrant community for all.

At Seattle Foundation, we believe that community is more than a place. It’s the shared understanding that our joy and well-being are tied to one another. Every day we work with nonprofits, philanthropists, and partners like you to strengthen community by igniting powerful philanthropy and advancing long-term solutions. Because it takes all of us to create a joyful region where every person can thrive.

Microsoft Disability Scholarship

This scholarship supports high school seniors living with a disability defined by WHO (World Health Organization — an impairment in a person’s body structure or function, or mental functioning (visual, hearing, mobility, cognitive, speech, or other disability). Eligible applicants must plan to study Engineering, Computer Sciences, Computer Information Systems, Law, Business (including Paralegal, Pre-Law, Finance, Business Administration, or Marketing) at an accredited two- or four-year college, university, or vocational-technical school. This scholarship is a $5,000 award with up to eight (8) scholarships granted.

Law Education - Higher Education Computer Science & Engineering +4 more

Exemplary Pathways to STEM Graduate Education: Seed

Alfred P Sloan Foundation
Private
United States
Up to US $250,000
The Alfred P. Sloan Foundation's initiative, "Creating Equitable Pathways to STEM Graduate Education: Seed," aims to enhance graduate education access for students from Minority Serving Institutions (MSIs). The program provides grants of up to $500,000 to foster partnerships between MSIs and various higher education institutions. Projects should focus on overcoming barriers to success in graduate studies, including recruitment and admission processes, thereby promoting equitable learning environments in STEM fields.
Astronomy & Astrophysics Biology Chemistry +10 more

Exemplary Pathways to STEM Graduate Education: Planning

Alfred P Sloan Foundation
Private
United States
Up to US $75,000
The Alfred P. Sloan Foundation's Creating Equitable Pathways to STEM Graduate Education initiative aims to foster partnerships between Minority Serving Institutions (MSIs) and graduate programs. By addressing barriers in graduate education, the initiative seeks to promote equitable learning environments. Planning grants will support collaborations that assess needs and develop systemic changes to enhance pathways for students in STEM fields, ensuring that all students can thrive in their academic pursuits.
Astronomy & Astrophysics Biology Chemistry +10 more

LabCorp Charitable Foundation Grants

Labcorp Charitable Foundation
Private
United States
Unspecified amount
The Labcorp Charitable Foundation, a private 501(c)(3) entity, aims to enhance healthcare access and education for all. With grant opportunities focusing on food programs, healthcare services for underserved populations, and STEM initiatives, it seeks to support community health and well-being. Organizations eligible for funding must be U.S.-based and hold tax-exempt status. Requests are reviewed biannually, in March and September, to foster impactful community projects.
Education Community Services Health & Medicine +5 more

Strategic Projects: Capital Grants

M J Murdock Charitable Trust
Private
United States
More than US $100,000
The Strategic Projects: Capital Grants by the M J Murdock Charitable Trust offer vital funding opportunities for nonprofit organizations in the Pacific Northwest. These grants support transformative projects that enhance community well-being through construction, renovation, and infrastructure investments. Eligible entities include 501(c)(3) nonprofits and government entities. The Trust emphasizes projects that demonstrate strong community impact and funding diversification, ensuring sustainable growth and lasting benefits for the communities served.
Nonprofit Growth & Development Art & Culture Education +6 more

Strategic Projects: Equipment & Technology Grants

M J Murdock Charitable Trust
Private
United States
More than US $50,000
The M J Murdock Charitable Trust offers Strategic Projects: Equipment & Technology Grants to nonprofits in the Pacific Northwest. These grants focus on capacity-building projects and essential equipment, requiring recipients to cover at least 50% of costs. Eligible organizations include 501(c)(3) nonprofits and tribal entities. Priority is given to projects enhancing community services, education, and environmental stewardship, supporting initiatives that foster human flourishing and demonstrate diversified funding.
Art & Culture Education Community Services +6 more

Margaret Thorne-Dilley Scholarship for Science Teachers Scholarship

Beckley Area Foundation
Private
United States
Unspecified amount

Mission Statement

Beckley Area Foundation exists to inspire and facilitate generous charitable giving that advances our community.

The Beckley Area Foundation is committed to enriching lives and strengthening communities across Southern West Virginia.

Scholarship

Supporting Student Success

The Beckley Area Foundation proudly manages scholarship funds established by individuals, businesses, and organizations dedicated to helping students pursue higher education. Many of these scholarships are tailored for specific schools, fields of study, or graduates from local high schools, while others offer broader opportunities. No matter the path, our scholarships aim to support students from our region as they work toward achieving their educational goals.

Margaret Thorne-Dilley Scholarship for Science Teachers Scholarship

Eligibility

Equally weighted as a need and merit based award for a Raleigh County high school graduate with a 3.5 cumulative GPA; Pursuing baccalaureate degree in education at an accredited institution; Preference will go to students pursuing a science field including the biological, physical and natural sciences. If none apply with the preferences listed, mathematics will also be considered.

Education Educational Access & Equity Education - Higher Education +5 more

The Slomo and Cindy Silvian Foundation Grant

Slomo And Cindy Silvian Foundation Inc
Private
United States
Unspecified amount
The Slomo and Cindy Silvian Foundation Grant supports a range of subjects including education, children's welfare, medical care, medical research, and Jewish philanthropic endeavors. Established in honor of Cindy Silvian, the foundation has awarded over $30 million since 2008. Applications are by invitation only, and organizations must meet specific eligibility criteria to be considered for funding. This year, the foundation allocated over $2.4 million to more than 110 organizations, highlighting its commitment to impactful philanthropy.
Education Health & Medicine Child Welfare Services +5 more

Exemplary Pathways to STEM Graduate Education: Implementation

Alfred P Sloan Foundation
Private
United States
Up to US $500,000
The Alfred P. Sloan Foundation's Creating Equitable Pathways to STEM Graduate Education initiative aims to foster partnerships between Minority Serving Institutions (MSIs) and graduate programs to enhance equitable learning environments. Grants of up to $500,000 will support projects addressing systemic barriers, promoting effective practices, and ensuring seamless transitions from MSIs to advanced degrees in various STEM fields. The initiative seeks to create lasting impacts on student access and success in graduate education.
Astronomy & Astrophysics Biology Chemistry +10 more

Strategic Projects: Program & Staff Grants

M J Murdock Charitable Trust
Private
United States
More than US $50,000
The M J Murdock Charitable Trust offers the Strategic Projects: Program & Staff Grants to support nonprofits in the Pacific Northwest. These grants focus on capacity-building for mission-driven projects and infrastructure investments. Eligible organizations must demonstrate a commitment to community flourishing, with funding available for new programs or expansion of existing ones. The Trust prioritizes initiatives that align with its strategic goals, fostering sustainable nonprofit growth and impact in the region.
Art & Culture Education Community Services +6 more

Zimmerman, Edward and Beverly Memorial Scholarship Fund

Noble County Community Foundation
Private
United States
US $1,000
The Zimmerman, Edward and Beverly Memorial Scholarship Fund offers $1,000 to West Noble High School seniors pursuing higher education at a college or university, with priority given to those demonstrating community service and maintaining a GPA between 2.50 and 3.00. Preference is also given to students studying agriculture, education, social work, or accounting. This scholarship reflects the values of its donors, Edward and Beverly, who were dedicated community members and supporters of local education.
Mathematics Education Human & Social Services +5 more

Pat and John MacTavish Fund

Grand Haven Area Community Foundation
Private
United States
Unspecified amount
The Pat and John MacTavish Fund, established in 2007 by John Mac Tavish in memory of his wife Pat, provides scholarships aimed at encouraging young women to pursue higher education in the hard sciences. Awarded by the Grand Haven Area Community Foundation, scholarships are competitive and based on criteria such as financial need and academic achievement. Applicants from Northern Ottawa County or specific school districts are eligible. The fund emphasizes the importance of education in fields such as math, chemistry, and computer science.
Education - Higher Education Educational Access & Equity Computer Science & Engineering +6 more

Cecelia Springmeyer Memorial Scholarship

Decatur County Community Foundation Inc.
Private
United States
More than US $1,000
The Cecelia Springmeyer Memorial Scholarship, managed by the Decatur County Community Foundation, aims to support North and South Decatur students pursuing post-secondary education in law enforcement, criminal justice, animal husbandry, agronomy, or teaching. Applicants must reside within the Decatur County Community Schools district and may receive a minimum scholarship of $1000 to ease their educational costs. For more details, visit ndsdscholarships.com.
Academic Scholarship Programs Education - Higher Education Law +5 more

Menasha Corporation Foundation Grant

Menasha Corporation Foundation
Corporate
United States
Unspecified amount
The Menasha Corporation Foundation, established in 1953, supports nonprofit organizations across North America, focusing on community betterment, education, environmental sustainability, and health initiatives. Grants are awarded to projects that enhance the lives of individuals and strengthen communities, particularly in areas where Menasha Corporation operates. Eligible organizations must be tax-exempt and prioritize non-public funding. The foundation also encourages involvement from Menasha Corporation employees in supported projects.
Art & Culture Education Basic Human Needs +5 more

PLTW Gateway- New Program (Huber)

Project Lead The Way Inc
Private
Aiken County, South Carolina, Cortland County, New York +14 more
US $20,000
The PLTW Gateway grant supports public schools in offering innovative STEM education. Grantees must provide at least one PLTW Gateway unit during the 2026-2027 academic year, with an additional unit each subsequent year. The total grant award is $20,000, distributed in two installments. Grantees are required to submit annual reports and assist in student and teacher surveys to ensure ongoing program improvement. Eligible districts span several states, including Arkansas, Georgia, and Texas.
Teacher Development & Training STEM / STEAM Education Energy +6 more

Herbert Foundation Grant

Herbert Foundation
Private
United States
Unspecified amount
The Herbert Family Foundation Grant focuses on philanthropic efforts that promote healing and fight hunger. Founded by Jim and Judi Herbert, both Distinguished Alumni of the University of Tennessee, the foundation supports health and food charities. It aims to advance medical research, education, and hunger relief initiatives, emphasizing sustainable practices and nutritional assistance. The foundation's mission reflects its commitment to impactful charitable causes that resonate personally with the founders.
Health & Medicine Food Access & Hunger Basic Human Needs +2 more

Michael Gregory Boyd Scholarship

The Community Foundation for the Greater Capital Region
Private
United States
Unspecified amount
The Michael Gregory Boyd Scholarship, offered by The Community Foundation for the Greater Capital Region, supports high school seniors from Troy-area schools who aim to pursue higher education. Eligible applicants must demonstrate a commitment to community service and belong to the African American or African descent groups. This scholarship opens doors for students seeking 2- or 4-year college programs or technical training, fostering educational growth and community involvement.
Academic Scholarship Programs Education - Higher Education Vocational & Trade Education +3 more

EA Funds: Animal Welfare Fund Grant

Centre For Effective Altruism Usa Inc
Private
Countries
Up to US $200,000
The EA Funds: Animal Welfare Fund Grant aims to enhance the welfare of nonhuman animals globally through strategic grants. It focuses on neglected regions, innovative research, and impactful advocacy, particularly for farmed and wild animals. The fund supports projects that alleviate suffering, promote alternatives to factory farming, and engage in policy advocacy. By contributing to this grant, you can help create a significant positive impact on animal welfare and support initiatives that are often overlooked.
Animal Welfare - General Animal Welfare - Domestic Animals & Pets Farms & Farming +2 more

Private Grants for Nonprofits in South Carolina Highlights

Looking for private grants for nonprofits in South Carolina?


Read more about each grant below or start your 14-day free trial to see all private grants for nonprofits in South Carolina recommended for your specific programs.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Private Grants for Nonprofits in South Carolina

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

200+ Private grants for nonprofits in South Carolina grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

53 Private grants for nonprofits in South Carolina over $25K in average grant size

40 Private grants for nonprofits in South Carolina over $50K in average grant size

32 Private grants for nonprofits in South Carolina supporting general operating expenses

100+ Private grants for nonprofits in South Carolina supporting programs / projects

2,000+ Grants on Instrumentl focused on Art & Culture

500+ Grants on Instrumentl focused on Writing & Literature

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Private grants for Nonprofits in South Carolina?

Most grants are due in the first quarter.

Q1
28.9%
Q2
25.2%
Q3
24.8%
Q4
21.1%

Typical Funding Amounts

What's the typical grant amount funded for Private Grants for Nonprofits in South Carolina?

Grants are most commonly $15,000.

$500 $500 Min.
$15,000 $15 K Median
$535,356 $535.4 K Average
$40,331,313 $40.3 M Max.

Average Grant Size

What's the typical amount funded for South Carolina?

Grants are most commonly $74,506.

$74,506

Total Number of Grants

What's the total number of grants in Private Grants for Nonprofits in South Carolina year over year?

In 2024, funders in South Carolina awarded a total of 24,410 grants.

2022 21,855

2023 21,722

2024 24,410

Top Grant Focus Areas

Among all the Private Grants for Nonprofits in South Carolina given out in South Carolina, the most popular focus areas that receive funding are Education, Philanthropy, Voluntarism & Grantmaking Foundations, and Human Services.

1. Education

2. Philanthropy, Voluntarism & Grantmaking Foundations

3. Human Services

Funding Over Time

How is funding for Private Grants for Nonprofits in South Carolina changing over time?

Funding has increased by 22.06%.

2022 $1,534,818,247

2023 $1,485,349,233
-3.22%

2024 $1,813,067,383
22.06%

South Carolina Counties That Receive the Most Funding

How does grant funding vary by county?

Greenville County, Richland County, and Charleston County receive the most funding.

County Total Grant Funding in 2024
Greenville County $580,646,902
Richland County $413,417,941
Charleston County $355,724,083
Spartanburg County $325,246,878
Pickens County $159,596,081