Best Unrestricted Grants for Nonprofits in South Carolina

The National Multiple Sclerosis Society offers Postdoctoral Fellowships to support innovative research aimed at advancing the understanding and treatment of multiple sclerosis. These fellowships are designed for promising researchers holding advanced degrees, providing funding for training that enhances their ability to conduct impactful studies. The Society prioritizes applications that align with high-priority research questions outlined in its Pathways to Cures Roadmap, emphasizing the importance of diverse methodologies and engagement with underserved populations.

The AGA Abstract Award for Health Disparities Research provides a $500 travel grant for graduate students, medical students, residents, clinical fellows, and postdoctoral fellows who present research on health disparities at Digestive Disease Week® (DDW). This award aims to enhance interest in gastroenterology research and improve access to care for underserved populations. It recognizes outstanding abstracts accepted by AGA, fostering future careers in digestive disease research among young professionals.

Community Foundation for Mason County, MI

At the Community Foundation for Mason County, we work with donors, grantees, and advisors to address key community issues. As a leader in community philanthropy, building a vibrant community with great opportunities for all, we are focused on advancing education, increasing recreation opportunities, and community and economic development.

The mission of the Community Foundation is to engage donors and connect them with opportunities to make a lasting impact, build community endowment, provide leadership on key issues, and make grants that reflect the communities we serve.

Joe Lancour Memorial Scholarship

This scholarship has been made possible by the generosity of the family of Joe Lancour, who established the Joe Lancour Memorial Scholarship Fund of the Community Foundation for Mason County.

Joe Lancour served our country in Afghanistan where he lost his life. Joe was active in sports and graduated in 2004 from Ludington High School. He was artistic in many ways and loved to cook. His mother Starla Owens championed this scholarship fund to honor his memory.

The American Epilepsy Society offers Predoctoral Research Fellowships to support students conducting epilepsy-related dissertation research under expert mentorship. Proposals in basic, translational, or clinical research are encouraged. Each fellowship provides up to $30,000 for stipend and travel to the AES Annual Meeting for one year, along with a one-year AES membership. The number of awards varies annually based on available funding.

The American Epilepsy Society offers Postdoctoral Research Fellowships to support trainees conducting research on epilepsy's causes, treatment, and consequences. These fellowships provide up to $49,000 for stipend and benefits, $1,000 for travel to the AES annual meeting, and complimentary membership. Proposals can be basic, translational, or clinical research, and the number of awards depends on available funding.

The Teaching Health Center Graduate Medical Education (THCGME) Program aims to ensure the sustainability of primary care residency training in community-based ambulatory patient care centers. By providing essential funding, this program supports the development of healthcare professionals who are equipped to deliver high-quality care, particularly in rural and underserved areas, enhancing the capacity to meet diverse health needs across various populations.

Emand Hamad, M.D. Healthcare Career Scholarship

Provides scholarships to students planning on majoring in a healthcare major.

This grant mechanism will focus on furthering the development of novel strategies towards improving the treatment of Small Cell Lung Cancer (SCLC). Work supported through this mechanism will address important areas of need across the entire care continuum and have the immediate potential to increase survivorship. It is expected that correlative translational research will be proposed that will enhance the understanding of SCLC.The overarching theme of the proposals should be centered around understanding the biology of SCLC and developing strategies toward improving outcomes for patients with SCLC. We will encourage applications on a wide variety of topics related to SCLC, including but not limited to the following:

• Advanced Screening and Diagnostic Technologies
  • Utilize liquid biopsies and circulating tumor DNA (ctDNA) to enhance early detection and monitoring of SCLC, providing non-invasive diagnostic and prognostic solutions
  • Investigate the clinical utility of blood-based biomarkers for improving SCLC diagnosis, monitoring treatment response, and predicting outcomes
  • Leverage artificial intelligence for the early detection of SCLC

• Disease Progression and Acquired Resistance
  • Study of molecular + clinical characteristics of rapid progressors vs. long-term responders in SCLC to tailor personalized treatment approaches
  • Leverage radiomics to identify predictive or prognostic factors such as treatment response, risk of pneumonitis, and likelihood of brain metastases
  • Investigate the underlying mechanisms of primary and acquired resistance to chemotherapy and immunotherapy in SCLC
  • Identify and validate biomarkers indicative of disease progression and/or therapeutic resistance

• Biomarkers and Immuno-Oncology
  • Identify and validate biomarkers that can predict greater responses to immunotherapy treatments in SCLC, enhancing patient selection and treatment efficacy

• Biospecimen-based research
  • Leverage real-world patient tissue and/or blood samples to enable:
    • Longitudinal studies of SCLC progression from limited-stage to extensive-stage disease
    • Investigation of tumor and microenvironmental changes before, during, and after treatment to understand the evolution of resistance
  • Develop a centralized infrastructure for biospecimen collection, with standardized protocols and accessible repositories to facilitate broad research collaboration

These awards provide a maximum of $500,000 in funding over a period of three years.

The Bay Area Lyme Foundation's Emerging Leader Award supports innovative research in Lyme disease, offering two $150,000 grants to post-doctoral and early-career scientists. Applicants are encouraged to propose proof-of-concept projects that enhance diagnostics or therapeutics. The award seeks to attract talent and foster scientific leadership in biomedical sciences. Evaluation criteria include the potential for novel therapies, scientific rationale, and support from institutions. This opportunity is ideal for those new to tickborne disease research.

The American Epilepsy Society offers Research and Training Fellowships for Clinicians, providing up to $75,000 for one year to support clinical fellows or new faculty aiming to advance in epilepsy research. This fellowship encourages proposals across basic, translational, and clinical research. It also includes $1,000 for travel to the AES Annual Meeting, membership benefits, and complimentary registration, fostering collaboration and knowledge sharing in the epilepsy research community.

The American Epilepsy Society's Junior Investigator Research Awards support early-career researchers in epilepsy. The awards, offering up to $50,000 for one year, aim to enhance the ability of new investigators to secure longer-term funding from sources like the NIH. Proposals are encouraged across a range of epilepsy research, including basic, translational, and clinical studies, as well as health services research. This initiative also includes complimentary membership to the AES Annual Meeting.

The AICEF Cultural Grant aims to enhance cultural ties between the United States and Indonesia by funding projects in the performing, visual, and literary arts. With grants ranging from $1,000 to $5,000, the foundation seeks to support distinguished individuals and groups whose work is accessible to the public and fosters goodwill between the two nations. This initiative not only promotes artistic excellence but also bridges cultural exchanges for a diverse audience.

The AISES National Conference Travel Scholarship provides financial support for full-time students in STEM fields to attend the annual conference. Covering registration, airfare, and lodging, recipients must commit to attending all events and uphold the AISES Code of Conduct. Selection is based on the quality of essays, letters of recommendation, and academic performance. Announcements for awarded scholarships will be made in late August/early September 2025, facilitating networking and professional development for indigenous students.

The OVC FY 2026 Preventing Trafficking of Girls program aims to provide crucial prevention and early intervention services for girls at risk of human trafficking. This initiative, backed by the US DOJ's Office of Justice Programs, supports efforts to protect vulnerable populations, including young women up to age 25, from both sex and labor trafficking. Applicants are encouraged to outline their strategies to effectively serve survivors and address diverse needs in their proposals.

The OAR Community Grant aims to enhance the quality of life for autistic individuals by funding community-led projects that address physical health and support services. Grants ranging from $1,000 to $15,000 are available for initiatives designed to produce practical tools and resources. Eligible applicants include family members, autistic individuals, and community organizations committed to improving the lives of those affected by autism. Projects should be innovative, publicly accessible, and focus on priority topics such as health systems and community services.

The Retina Society, Inc.

The Retina Society was founded in 1968 exclusively for educational and scientific purposes concerning the diagnosis, care and treatment of diseases and injuries to the retina. The Retina Society began as an outgrowth of alumni meetings of Retina Associates, a retina practice founded in Boston in 1951 by Charles L. Schepens. Dr. Schepens is credited with establishing retina surgery as a sub-specialty.  

Our mission is to reduce worldwide visual disability and blindness by promoting the education and professional interaction of vitreoretinal specialists, providing optimal care for patients with vitreoretinal diseases, and encouraging, through clinical and basic research, the discovery and development of new means to further patient care.

Retina Society Underrepresented in Medicine (RESOURCE) Mentoring Program

The Retina Society Underrepresented in Medicine (RESOURCE) Mentoring Program was created to engage and interest ophthalmology residents from underrepresented populations* in research and in pursuing careers in the retina subspecialty through dedicated mentoring exposure. The program will pair ophthalmology residents from underrepresented backgrounds with Retina Society mentors, with the goal of providing the residents with research and career mentorship.

*The American Association of Medical Colleges definition of underrepresented in medicine is: "Underrepresented in medicine means those racial and ethnic populations that are underrepresented in the medical profession relative to their numbers in the general population." We define the following groups as underrepresented: Black (African American or African), Latino/Hispanic, American Indian, Alaska Native, Native Hawaiian or Pacific Islander. We will also be considering applicants from LGBTQIA+ and socioeconomically underprivileged backgrounds.

Mentors will work with their designated mentees on research projects that will be presented at the Retina Society Annual Meeting in 2027 and submitted for publication consideration. Mentors and mentees will be acknowledged at the Retina Society Annual Meeting.

The Raskob Foundation offers domestic grants to organizations located in the U.S. and its territories. Founded in 1945, this private, non-profit foundation focuses on supporting Catholic institutions. Eligible applicants must be tax-exempt 501(c)(3) organizations, listed in the P.J. Kenedy Official Catholic Directory. However, requests from individuals and certain projects, such as debt reduction or completed projects, are not accepted. The foundation emphasizes its commitment to philanthropy and community support.

The American Epilepsy Society offers Seed Grants to support established researchers in exploring innovative research methodologies and collaborations. These grants aim to foster new lines of inquiry in epilepsy research. Notably, proposals that align with specific partner priorities may enjoy waived eligibility criteria, enhancing funding opportunities. This initiative seeks to advance understanding and treatment of epilepsy through novel research avenues.

The American Heart Association (AHA) is launching the RFP for a Strategically Focused Research Network (SFRN) aimed at enhancing the early detection and delaying the progression of valvular heart disease. This initiative seeks collaborative proposals from researchers to address critical questions and advance understanding in this field. With a maximum budget of $4.4 million and a duration of four years, the AHA plans to award at least three grants based on scientific merit and alignment with its mission.

Rapid Response Grants 

Emergency funding after mass tragedies.

In the wake of tragic mass events, such as shooting, speed matters. Our Rapid Response Grants provide expedited funding to victims and their families when time is of the essence. These grants ensure that families aren’t left waiting for critical support when they need it most.

• Awarded swiftly after mass casualty events
• Designed to provide urgent, compassionate support in crisis situations

The American Society for Theatre Research (ASTR) Sally Banes Publication Prize celebrates outstanding publications that explore the relationship between theatre and dance. This award alternates between recognizing books and essays based on even and odd years, respectively. Eligible works must have been published within the last two years. The award includes a $500 prize and free conference registration, encouraging scholarly contributions to the field.

The Rapid Outcomes from Agricultural Research (ROAR) Grant Program, managed by the Foundation for Food and Agriculture Research (FFAR), provides urgent funding for research addressing unexpected threats to the food supply. This program supports diverse projects related to pest and pathogen outbreaks, facilitating quicker responses than traditional funding avenues. With grants up to $150,000, ROAR aims to enhance agricultural resilience by fostering collaborations among researchers, institutions, and organizations to combat emerging challenges in the food and agriculture sector.

The Exploratory Grant Award aims to enhance workforce diversity in basic cancer research by supporting junior and Early Stage Investigators from underrepresented groups in the biomedical and social sciences. This initiative provides essential funding to bridge the gap for researchers completing their training, ensuring they have the resources needed to develop larger grant applications. Applications are due by 5:00 PM local time of the applicant organization, emphasizing the importance of timely submissions.

The TTP Bridge Program aims to enhance the safety and accessibility of bridges in Tribal communities, addressing the urgent need for infrastructure improvements. With aging bridges affecting economic development and children's transportation, this program allows federally recognized Indian Tribes to apply for funding for planning, construction, and rehabilitation of bridges. By focusing on TTP bridges in poor condition, the initiative seeks to strengthen economic foundations and ensure better connectivity with markets, benefiting both families and communities.

Community Foundation for Mason County, MI

At the Community Foundation for Mason County, we work with donors, grantees, and advisors to address key community issues. As a leader in community philanthropy, building a vibrant community with great opportunities for all, we are focused on advancing education, increasing recreation opportunities, and community and economic development.

The mission of the Community Foundation is to engage donors and connect them with opportunities to make a lasting impact, build community endowment, provide leadership on key issues, and make grants that reflect the communities we serve.

George Dila Memorial Scholarship

This scholarship has been made possible by the generosity of Wayne and Jeanie Mortenson, who established the George Dila Memorial Scholarship Fund of the Community Foundation for Mason County to honor the memory of their dear friend, George Dila.

This scholarship is for graduating senior(s) of Ludington High School pursuing a degree or certification at any two or four-year accredited college, university, or vocational/technical school.

The William L. and Diane C. Wilson Scholarship for Karst Science, established in 2002, honors the legacy of William L. Wilson and aims to support innovative karst scientists. Funded by Diane C. Wilson, it provides a one-time award of $2,500 and recognition at the KWI spring banquet. Eligible candidates must be enrolled in a master's program focused on karst science and its subfields, while PhD students are excluded. This scholarship fosters the growth of new talent in karst research.

The Fiscal Year 2026 Flood Mitigation Assistance program aims to enhance flood mitigation funding delivery, focusing on the needs of disaster survivors. This federal initiative, managed by FEMA, provides essential funds to states, territories, and local governments to mitigate flood risks and reduce repetitive damage to properties insured under the National Flood Insurance Program. The program supports various activities designed to lower the financial exposure of the NFIP while promoting community resilience against flooding.