Best Grants for Small Nonprofits in South Dakota

The Maximizing Opportunities for Scientific and Academic Independent Careers (MOSAIC) program aims to enhance diversity in research by supporting early career investigators from underrepresented backgrounds. This initiative offers a K99/R00 career transition award for postdoctoral scholars and a UE5 cooperative agreement that provides mentorship and professional development. The program's goal is to ensure successful transitions into independent, tenure-track faculty roles in NIH mission areas, ultimately fostering a more inclusive scientific community.

The Alternative Fuel Foundation Grant aims to support educational institutions in developing programs focused on renewable energy and environmental sustainability. Grants typically range from $250 to $500, with larger amounts considered on a case-by-case basis. Eligible applicants include public or private K-12 schools and universities. The foundation encourages projects that promote alternative fuels and community involvement, with a preference for initiatives that can be completed within a year.

The Neag Foundation Grant aims to foster positive change in education, healthcare, and the arts. Supporting initiatives in Pennsylvania and Connecticut, the foundation focuses on enhancing educational opportunities, advancing healthcare interventions, and promoting the arts and humanities. By encouraging innovative projects that receive community support, it seeks to improve the quality of life for individuals and families. Organizations with a 501(c)(3) status are encouraged to apply for funding opportunities that align with these goals.

The Research Opportunities for New and At-Risk Investigators (R01 Clinical Trial Optional) program invites applications that promote workforce diversity in health-related sciences. This initiative encourages researchers from underrepresented backgrounds to propose independent research projects in alignment with NIH's mission. Important deadlines for standard and renewal applications range from February 2025 to November 2027. This effort aims to enhance diversity and inclusion within the scientific community.

The Nathan & Sarah Chesin and Bernard & Mollie Steuer Fellowships, established by the American Jewish Joint Distribution Committee (JDC) in 2019, support scholars in graduate, post-doctoral, or independent research in the JDC Archives. With a rich collection documenting modern Jewish history, the fellowship encourages innovative research in humanitarian assistance and related fields. Each year, one fellowship is awarded, culminating in a public presentation by the recipient, fostering a greater understanding of the Jewish experience.

Basin Electric Power Cooperative's Charitable Giving Program focuses on supporting communities across its nine-state service territory. The program reviews funding requests periodically and allocates donations to various categories, including education, health services, civic betterment, and cultural initiatives. Additionally, it offers matching funds for member donations and contributes surplus office equipment to organizations in need. This commitment to community growth and sustainability reflects Basin Electric's mission to enhance the well-being of its members.

The Procter & Gamble U.S. Large Site Community Grant supports initiatives that enhance the lives of individuals within 50 miles of P&G facilities. Focused on areas like infant development and hygiene, this competitive grant seeks to partner with organizations aligned with its mission. Interested groups should verify eligibility through the P&G grant portal. While many applications are received, only a select few will be funded due to high demand.

The National Science Foundation (NSF) offers funding opportunities through the Research in Undergraduate Institutions (RUI) and Research Opportunity Awards (ROA) programs. These initiatives support faculty research at predominantly undergraduate institutions, fostering professional engagement and educational integration. Eligible institutions include accredited colleges and universities that award degrees in NSF-supported fields but have limited Ph.D. production. Proposals are evaluated by NSF programs based on disciplinary relevance and funding is allocated within existing research and education programs.

Marion Community Foundation

Since 1998, area residents have been turning to Marion Community Foundation to make their philanthropic giving as effective as possible. We are a public charity serving thousands of people who share a common concern … improving the quality of life in Marion County. We use distributions from the more than 500 charitable funds — created by generous, local donors — to award more than $2.5 million in grants and scholarships each year to many of the humanitarian, educational and cultural organizations in this remarkable community we call home.

Marion Community Foundation is the area’s leading philanthropic organization, providing charitable donors the opportunity to easily create endowment funds to benefit and support our community through grants and scholarships. We serve communities throughout Marion County through philanthropy, leadership, and civic engagement.

Art & Anne Huggler Memorial Scholarship

The Art & Anne Huggler Memorial Scholarship Fund supports local students pursuing a degree in education or engineering.

Art hailed from Harrisburg, Pennsylvania, graduating with a degree in electrical engineering from Penn State. He was a Navy veteran of World War II and worked for GTE for 35 years. He enjoyed travel and golf and was a licensed pilot. Anne was a teacher and homemaker. They are the parents of two, grandparents of five and great-grandparents of nine. The couple was active with St. Paul’s Lutheran Church, where Art directed Art Market Marion.

The Huggler Scholarship seeks especially to assist Marion area students with substantial financial need. It was established in 2015 by their daughter, Linda Halt.

The Genesis Mission by the DOE aims to transform science and energy through AI by inviting interdisciplinary teams to tackle significant challenges in energy, environment, and nuclear sectors. With multiple deadlines for FY26 Phase I and II applications, the initiative encourages leveraging diverse scientific resources to enhance R&D workflows. Successful proposals could integrate AI advancements into the American Science Cloud, fostering innovation in critical areas like advanced manufacturing and quantum information science.

The NIH Midcareer Investigator Award in Patient-Oriented Research (K24) supports mid-career health-professional doctorates by providing protected time for patient-oriented research (POR). This grant also enables recipients to serve as research mentors for clinical residents, fellows, and junior faculty. Key deadlines for applications span from June 2024 to February 2027, ensuring ample opportunities for interested applicants to engage in impactful research and mentoring.

The NIH Midcareer Investigator Award in Patient-Oriented Research (K24) aims to support mid-career health professionals in conducting patient-oriented research while mentoring clinical residents and junior faculty. This grant offers protected time for research, ensuring participants can focus on impactful studies and foster the next generation of clinical researchers. Key deadlines for applications range from June 2024 to February 2027, with specific dates for standard, renewal, and AIDS-related submissions.

South Dakota Community Foundation

As a statewide community foundation, we work with donors, nonprofits and community leaders to strengthen philanthropy in South Dakota every day.

Grants

The South Dakota Community Foundation offers an array of grants to help state nonprofits realize their dreams and continue investing in their communities. 

Clark Area Foundation Grant

The Greater Clark Area Community Foundation (GCACF) will strive to support a broad spectrum of projects intended to improve and enhance the Clark County Area. Determination of recommendation for approval will be based upon need, creativity in addressing community concerns, community volunteer support, and accountability. The GCACF will use this as a guideline to determine the eligibility of your proposed project for funding.

• QUALIFICATION: Purpose of the project should fulfill a community need and preferably involve tangible, measurable, items or projects.

• VOLUNTEERISM: Projects which involve significant and continuous community volunteerism support will be favorably considered.

• DISCRIMINATION: Applications offering services exclusively to one gender, age group, religion or race will be closely scrutinized for discriminatory practices. Funding will be based on the needs of the individual being served.

• INNOVATION: The Clark Area Community Foundation goal is to funds a mix of ongoing, well-established projects as well as innovative projects designed to address existing community needs in innovative ways.

• PARTNERSHIP: The Foundation should not be the sole funding source of any Project and make awards contingent on proof of other funding sources: however, funding percentage of total project is at the discretion of the Foundation. Grants may also be made in the form of a challenge, to be met dollar-for-dollar by other sources. The Foundation prefers to be the last funder. Grants expire one year from the date awarded; if that should happen, the Foundation welcomes the project to reapply.

• CHALLENGE OR MATCHING GRANTS: The Clark Area Community Foundation encourages matching funds from all grant applicants. When the Board perceives the need for more local involvement and support of a given project; it may issue challenge grants in any proportion. Funding may be contingent upon acquisition of the required matching money. There may be times when the Clark Area Community Foundation perceives a need in the community is not being met. The Board then may issue a challenge grant or request a proposal to address that need.

The William E. Dean III Charitable Foundation, established in 2009, supports 501(c)(3) organizations in the U.S. and D.C. with a focus on animal welfare, education, human services, and religious initiatives. Grants are specifically aimed at programs aiding canines and veterans transitioning to civilian life, as well as preventing animal cruelty. Organizations must wait one grant cycle before reapplying, ensuring a fair distribution of funds to various causes.

The National Institute of Environmental Health Sciences (NIEHS) is seeking applications for research coordination and data support under the Health and Extreme Weather initiative. This funding opportunity aims to engage NIH grantees and the broader community by sharing best practices, developing training resources, and facilitating access to health and environmental data. The initiative will enhance collaboration, reduce duplication, and promote data standards to support impactful research and infrastructure activities.

The Science Ambassador Scholarship, funded by Cards Against Humanity, offers full tuition for women and non-binary students pursuing degrees in STEM fields. This scholarship is open to undergraduate students and high school seniors, regardless of U.S. citizenship, as long as they plan to attend college in the United States or its territories. Eligible applicants must major in science, technology, engineering, or math.

The Sam Noble Foundation Grant aims to uphold the philanthropic legacy of Lloyd Noble by funding agricultural research and supporting charitable initiatives that enhance health, education, and community strength. Geared towards 501(c)(3) nonprofits in the U.S., the foundation prioritizes projects in Oklahoma and does not entertain multiyear commitments or funding for individuals or for-profit entities. The foundation seeks to address agricultural challenges while expanding educational and health services.

The NIH Mentored Research Scientist Development Award (K01) aims to support emerging scientists by providing protected time for career development in biomedical, behavioral, or clinical sciences. This award, effective for three to five years, encourages research independence and may be beneficial for those transitioning fields or returning from a hiatus due to personal circumstances. Deadlines for applications vary, with important dates set for standard, renewal, and AIDS-related submissions.

The EA Infrastructure Fund Grant supports projects that enhance effective altruism by improving access to talent, capital, and knowledge. With grants typically ranging from $5,000 to $200,000, it welcomes applications from individuals, nonprofits, and academic institutions worldwide. However, individuals must ensure their projects conclude by August 31, 2025. The fund aims to amplify the impact of direct charitable work and foster a community committed to effective altruism principles.

The ROSES 2025: D.4 program by NASA focuses on enhancing theoretical and computational astrophysics through collaborative networks. It aims to address grand challenges in Time Domain Multi-Messenger Astrophysics by integrating diverse expertise from various fields. Researchers from U.S. institutions are encouraged to propose innovative tools for modeling complex multi-messenger phenomena, fostering interdisciplinary collaboration across academic, national laboratory, and private sectors to prepare the next generation of scientists.

 Parkston Area Foundation 

The Parkston Area Foundation (PAF) is a tax-exempt organization developed in 2004. Our mission is to promote philanthropy and support a wide range of social, economic, and charitable needs in the greater Parkston area.

The purpose of the PAF Board is to raise funds to create a community savings account which will grow and benefit the communities of Dimock, Milltown, Hillside, and Parkston. The funds are deposited with the South Dakota Community Foundation which invests the dollars and annually returns earned interest to the PAF for grant distributions. The Parkston Area Foundation has been annually awarding grants to support the community since 2007.

Grants

Since 2007, the Parkston Area Foundation has combined efforts with the Opie R. Benson and Helen A. Benson Community Improvement Foundation as well as the Avera St. Benedict Foundation in awarding grants every year. In 2007, the three foundations pooled monies and granted a total of $10,000 in funds. Since 2008, the foundations have continued to work together giving out grants each year, but have since each designated specific amounts to recipients.

Parkston Area Foundation Grant

Qualification

Purpose of the project should fulfill a community need and should involve a tangible and measurable means of evaluation.

Volunteerism

Projects that involve significant and continuous community volunteer support will be favorably considered.

Innovation

The Parkston Area Foundation (PAF) funds ongoing, well-established projects as well as innovative projects designed to address existing community needs in innovative ways.

Discrimination

Applications from persons and/or agencies offering services exclusively to one gender, age group, or race will be closely scrutinized for discriminatory practices. Funding will be based on the needs of the individuals being served.

Continued Funding

No guarantee of continued funding will be communicated until subsequent grant applications are reviewed. However, once initiated under foundation funding, projects with a good track record will be considered favorably in subsequent grant decisions. No more than three years of sequential grant funding shall be awarded to any one grantee for the same purpose.

Challenge Grants

The PAF encourages matching funds from all grant applicants. When the board perceives the need for more local involvement and support of a given project, it may issue challenge grants in any proportion. Funding may be contingent upon acquisition of the required matching money. There may be times when the PAF perceives a need in the community currently not being met. The board then may issue a challenge grant to the community or request a proposal to address that particular need.

The ISF Public Interest Legal Fellowship empowers American Muslims by providing opportunities in public interest law. This fellowship offers a salary of $70,000, professional development workshops, and mentorship to help fellows advance their careers. Applicants must be active members of the Muslim community, have graduated from law school within the last three years, and have secured a host organization for their project proposal. This initiative aims to increase representation and influence in policy-making.

The NIH Mentored Clinical Scientist Research Career Development Award (K08) aims to develop the research careers of individuals with clinical doctoral degrees. This program provides essential support and protected time for intensive, supervised research experiences in biomedical and behavioral fields, including translational research. Important deadlines for applications span from June 2024 to February 2027, accommodating various grant types, including standard and AIDS-related applications.

The NIH Mentored Research Scientist Development Award (K01) supports early-career scientists with up to five years of protected time for intensive research training in biomedical, behavioral, or clinical sciences. This award is tailored for those pursuing independence in research and is particularly beneficial for individuals transitioning fields or returning from a hiatus. Importantly, applicants must not lead independent clinical trials but may participate in trials overseen by mentors.

The Olney Medal, established in 1944 by the American Association of Textile Chemists and Colorists (AATCC), honors exceptional achievements in textile chemistry and related fields. It recognizes significant contributions to the development of chemical processes and agents in textile manufacturing. Open to all AATCC members for nominations, the award emphasizes the importance of innovation and public recognition in advancing textile sciences, a legacy of its founder, Dr. Louis Atwell Olney.

The OpenAI A People-First AI Fund supports U.S.-based nonprofits with 501(c)(3) status, focusing on AI literacy, community innovation, and economic opportunity. It aims to enhance public understanding of AI, promote participatory design in AI applications by communities, and expand access to meaningful work through inclusive practices. Organizations at all stages of AI adoption are encouraged to apply, especially those addressing the needs of traditionally marginalized populations. This initiative emphasizes equitable distribution of AI benefits.

The AAAS Early Career Award for Public Engagement with Science recognizes outstanding early-career scientists and engineers for their significant contributions to public engagement in science. Established in 2010, the award includes a $5,000 prize, a plaque, and recognition at the AAAS Annual Meeting. Eligible nominees must be actively conducting research in STEM fields and demonstrate engagement beyond their job responsibilities, with one awardee chosen annually.