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Best Operating Grants for Nonprofits in South Dakota

Find the perfect Operating grants for nonprofits in South Dakota on Instrumentl. 9,000+ Operating grants for nonprofits in South Dakota in the United States.

9,000+

Available grants

$3.26B

Total funding

$5K

Median grant

9,000+ grants
$3.26B total
$5K median

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9,072 Results based on applied filters

David W. McCoy Scholarship (MO)

Community Foundation of the Lowcountry
Private
United States
Unspecified amount
The David W. McCoy Scholarship, established by David W. McCoy in 2021, supports qualified students from Troy Buchanan High School pursuing undergraduate degrees in STEM fields. Administered by the Community Foundation of the Lowcountry, this scholarship aims to empower the next generation of leaders by providing essential financial resources. Eligible applicants must demonstrate academic excellence, leadership potential, and a commitment to their education, ensuring that deserving students have the opportunity to thrive in higher education.
Education - Higher Education Career / College Preparation STEM / STEAM Education

The Delesky-Wetmore Scholarship

Community Foundation of the Lowcountry
Private
United States
Unspecified amount
The Delesky-Wetmore Scholarship, established in October 2025 by Cathy Delesky and Doug Wetmore through the Community Foundation of the Lowcountry, aims to support high school seniors in Beaufort, Jasper, Hampton, or Colleton Counties, South Carolina. This scholarship focuses on students with financial need pursuing a four-year degree in STEM, finance, or economics, requiring a minimum GPA of 3.5 and above-average ACT or SAT scores.
Education - Higher Education Career / College Preparation STEM / STEAM Education

Dunkirk Community Funds: Marilee & Gayle Gaunt Scholarship

Portland Foundation
Private
United States
Unspecified amount
The Dunkirk Community Funds: Marilee & Gayle Gaunt Scholarship, established in 2007 by The Dunkirk Foundation, honors the memory of Betty L. Gaunt's daughters, Marilee and Gayle, who tragically passed away in 1966. This scholarship aims to support residents of Dunkirk, IN, or those living within two miles of its boundary, by providing financial assistance for educational and vocational training at post-secondary institutions.
Education - Higher Education Vocational & Trade Education Career / College Preparation

Ittleson Foundation: Environmental Program Grants

Ittleson Foundation
Private
United States
Unspecified amount
The Ittleson Foundation Environmental Program Grants support innovative projects that enhance environmental activism through education and grassroots efforts. In 2025, grants will focus on initiatives that strengthen environmental movements and engage new constituencies, particularly in environmental equity. The Foundation has provided resources since 1932 to improve public policy and community welfare, alternating its grantmaking focus annually between mental health and environmental initiatives.
Environmental Justice & Advocacy

Traumatic Brain Injury Model Systems Centers

US HHS: Administration for Community Living (ACL)
Federal Government
American Samoa, Guam +4 more
US $560,000 - US $640,000
The Traumatic Brain Injury Model Systems Centers aim to enhance TBI rehabilitation through evidence-based research. These centers focus on generating knowledge to improve health, community participation, and employment outcomes for TBI individuals. Funded by the US HHS Administration for Community Living, the grants support site-specific and collaborative research, contributing to a longitudinal database. Each center can receive varying funding amounts, depending on eligible database participants, with a project timeline of 60 months comprising five 12-month budget periods.
Disability Care & Services Neurological Diseases & Disorders Medical Rehabilitation

Conservation Service Corps Grants

Great Outdoors Colorado
Private
Colorado, Countries
Unspecified amount
The Conservation Service Corps Grants, funded by Great Outdoors Colorado, support outdoor recreation and natural resource projects by hiring youth and veterans through conservation service corps. Annually, $1.5 million is allocated for these initiatives, enabling crews to tackle various projects like trail maintenance, invasive species mitigation, and wildlife habitat improvement. This program not only enhances natural resources but also provides job training and leadership skills to over 1,700 young participants each year.
Habitat & Ecosystem Restoration

Promoting Cancer Surveillance Workforce, Education, and Data Use (363986)

Dept. of Health & Human Services: Centers for Disease Control & Prevention
Federal Government
American Samoa, Guam +4 more
Unspecified amount
This funding opportunity aims to enhance the cancer surveillance workforce through education and support for certified Oncology Data Specialists. The initiative will improve the quality and completeness of cancer data collected by the National Program of Cancer Registries. By fostering collaboration and promoting the value of cancer surveillance data, this program seeks to empower public health actions, research, and policy-making, ensuring a robust response to current and future cancer-related challenges.
Cancer / Oncology Epidemiology & Public Health Medical Education & Professional Training

Greater Minnesota Housing Infrastructure Grant Program

Minnesota Housing Finance Agency
State/Local Government
Aitkin County, Minnesota, Becker County, Minnesota +80 more
Up to US $500,000

Greater Minnesota Housing Infrastructure Grant Program

Grant funds can be used to cover up to 50% of capital costs of physical public infrastructure necessary to support a qualifying housing development. This may include sewers, water supply systems, utility extensions, streets and more, necessary to support single-family, multifamily, homeownership and rental housing development.

Grants are generally limited to:

  • $40,000 per lot for one to four units
  • $180,000 per lot for multifamily housing (five or more units/building)
  • $60,000 per manufactured housing lot
  • No more than $500,000 to any grantee or project over a two year period.

Applicants’ matching funds may include in-kind contributions, such as donation of land.

Equitable & Affordable Housing

Brees Dream Foundation Contribution Grant

Brees Dream Foundation
Private
United States
Unspecified amount
The Brees Dream Foundation Grant aims to enhance the lives of cancer patients while providing essential care, education, and opportunities for children and families in need. With the support of generous donors and partners, the Foundation is dedicated to advancing cancer research and offering vital resources to those facing challenges. This commitment reflects a profound dedication to improving quality of life and fostering hope in communities.
Cancer / Oncology Child Welfare Services Youth Services

BJA FY 2026 Emmett Till Unsolved Civil Rights Crimes Act Program

US DOJ: OJP Bureau of Justice Assistance
Federal Government
American Samoa, Guam +4 more
Up to US $645,000
The BJA FY 2026 Emmett Till Unsolved Civil Rights Crimes Act Program aims to assist state, local, and tribal law enforcement agencies in investigating and prosecuting civil rights offenses that resulted in death before December 31, 1979. This funding opportunity is part of the DOJ's broader commitment to enhance public safety, protect civil rights, and ensure justice for victims of violent crime. Applications are due on November 20, 2026.
Social Justice / Human Rights Crime & Justice Community / Public Safety +2 more

Diversity Leadership Fellowship

American Psychiatric Association Foundation
Private
United States
Unspecified amount

American Psychiatric Association Foundation

There is no health without mental health. The APA Foundation is working in your community to provide the support and resources we all need to prioritize mental wellbeing where you live, learn, work, worship, and play.

Backed by the medical expertise of the APA and industry-leading strategic partners, we administer community-changing programs, public education campaigns, grants, and awards aimed at increasing mental health literacy, connecting individuals to needed care, and shifting attitudes toward mental health.

Our Mission is to promote the mental health and well-being of individuals and communities. Our Vision is a mentally healthy nation for all – where we live, learn, work, worship, and play.

Diversity Leadership Fellowship

The Diversity Leadership Fellowship identifies and motivates minority psychiatry residents or those interested in minority and vulnerable populations to become well equipped to teach, administer, and provide culturally competent, evidence based mental health and substance abuse services to diverse minority groups and at-risk populations. These populations include—but are not limited to—American Indians/Native Alaskans, Asian Americans/Native Hawaiians/Native Pacific Islanders, Blacks/African Americans, Hispanics/Latinos, LGBTQ, and religious minorities. Program Benefits:

  • Sponsorship to attend a minimum of four APA meetings:
    • Two APA Annual Meetings
    • Two Fellowship Forums
  • Develop leadership skills in the field of psychiatry and advance understanding of the life experiences of racial ethnic minority communities
  • Gain an understanding of APA/APAF Governance through observation and service on an APA Council, Committee, or APAF initiative
  • Have the opportunity to sit on the APAF Board of Directors as a non-voting member (one Diversity Leadership fellow allowed)
  • Cultivate a professional network with psychiatrists interested in minority mental health and services through exclusive events and engagements with APA leaders. Establish relationships and peer-mentorship with a diverse group of resident fellows with similar career interests and goals
Medical Education & Professional Training Mental Health & Psychiatric Diseases Diversity, Equity & Inclusion

Visa Foundation U.S. Small Business Growth and Innovation Program

Rockefeller Philanthropy Advisors Inc
Private
U.S. Territories, United States
US $100,000 - US $250,000

Across the United States, small and micro businesses (SMBs) play a critical role in driving economic opportunity, job creation, and community prosperity. Yet many entrepreneurs continue to face challenges accessing the training, resources, and support needed to grow and remain competitive in an evolving economy. To help address these needs, Visa Foundation is committing $2M to launch an open-call grant program that will support nonprofit Entrepreneurial Support Organizations (ESOs) that provide direct services to SMBs. Through this program, Visa Foundation aims to strengthen the capacity of high-impact organizations that help small businesses build greater resilience, expand economic opportunity, and contribute to thriving local economies. 

Business Development Entrepreneurship

Supplemental Training for Education Program (STEP)

Society of Toxicology
Association/Society
United States
US $1,000
The Society of Toxicology offers the Supplemental Training for Education Program (STEP), which provides up to $1,000 to support graduate students in toxicology seeking additional training to address skill gaps. Eligible applicants must be PhD students who have completed coursework and passed comprehensive exams. The funding covers workshops or courses not available through their graduate program, enhancing career prospects in toxicology.
Environmental Chemistry & Toxicology

Quality Improvement Solutions for the Diagnosis and Management of Migraine and Headache Disorders

Pfizer, Inc.
Corporate
Canada, United States
Up to US $250,000
Pfizer, in collaboration with the American Headache Society, invites innovative proposals for quality improvement initiatives targeting gaps in headache medicine. The focus is on enhancing patient outcomes through effective diagnosis, treatment, and management strategies, as well as education in medical training. This grant aims to develop widely usable tools and information that promote patient-centered care and equity for those affected by migraine and headache disorders.
Chronic / Acute Pain Neurological Diseases & Disorders

Advancing Care for Patients with Advanced ALK+ Non-Small Cell Lung Cancer (NSCLC)

Pfizer, Inc.
Corporate
Australia, Europe +2 more
Up to US $100,000
Pfizer is launching a grant initiative to enhance care for patients with advanced ALK+ non-small cell lung cancer (NSCLC). This program aims to support independent medical education projects focusing on patient and caregiver preparation for ALK inhibitor therapy, side-effect management, and the development of resources that promote informed decision-making and accessibility. By addressing the challenges faced by this patient population, the initiative seeks to improve treatment outcomes and quality of life.
Lung Cancer

Tilghman, Linda Healthcare Scholarship

Noble County Community Foundation
Private
United States
US $1,000
The Linda Tilghman Healthcare Scholarship supports Noble County high school seniors enrolled in the Primary Healthcare Program at Impact Institute. Applicants must pursue a degree in healthcare and maintain a minimum GPA of 2.50. This one-time $1,000 award can be used for tuition and academic fees. To apply, students must submit an essay on their healthcare outlook and provide a reference from a teacher or employer. Funds not used for educational purposes must be returned.
Career / College Preparation Medical Education & Professional Training Academic Scholarship Programs

Bridgestone Americas Trust Fund: Adaptive Sports in Schools Mobility Grants

Bridgestone Americas Trust Fund
United States
US $25,000

Adaptive Sports in Schools Mobility Grants

Request for Proposals

More than 7 million students in the U.S. receive special education services for disabilities in public schools. A 2010 study by the U.S. General Accountability Office found that students with disabilities participated in athletics at significantly lower rates than their peers. Currently, 2,490 k-12 public schools in the U.S. are members of the American Association of Adaptive Sports Programs schools and have adaptive sports programs for students.

The Bridgestone Americas Trust Fund seeks public schools pursuing funding to start adaptive sports programs or increase access to adaptive sports and equipment for children and youth. Bridgestone is offering eight $25,000 “mobility” grants to organizations that can establish new athletic programming for students with disabilities. Organizations must articulate a clear plan to provide access to new athletic programs for students with disabilities in one or more public schools for students grades K-12.

Education - K through 12 Sports & Athletics Youth Services +1 more

AGA: Caroline Craig Augustyn & Damian Augustyn Award in Digestive Cancer

American Gastroenterological Association
Association/Society
Canada, Mexico +1 more
US $40,000
The AGA: Caroline Craig Augustyn & Damian Augustyn Award in Digestive Cancer offers $40,000 for one year to early career investigators holding a career development award focused on digestive cancer research. This grant aims to support innovative studies in pathogenesis, prevention, diagnosis, and treatment. Applicants must provide evidence of their current awards, a recommendation letter, and demonstrate how the AGA funding will facilitate their transition to independence in research.
Gastrointestinal Cancers

Pat R. Gereau R.N. Scholarship

Tulsa Community Foundation
Private
Tulsa County, Oklahoma, United States
Unspecified amount

Scholarship funds at TCF annually provide approximately $20 million in educational aid for students at institutions of higher learning. Each donor or group of donors determines the conditions for which the scholarships are awarded. The diversity of eligibility criteria reflects the variety of donor motivations to create or support scholarship funds.

Pat R. Gereau R.N. Scholarship

Available to students who are in an undergraduate program of study and pursuing a career in nursing at an accredited U.S. college, university, technical program or trade school in Tulsa, Oklahoma area.

Education - Higher Education Nursing Vocational & Trade Education

Roesler, Max and Elizabeth Memorial Scholarship Fund

Noble County Community Foundation
Private
United States
US $1,500
The Roesler, Max and Elizabeth Memorial Scholarship Fund supports non-traditional students aged 25 and older in Noble County, Indiana, pursuing higher education or retraining. This fund awards $1,500 to applicants enrolled in any accredited college, university, or trade school. Applicants may be full-time or part-time students and may reapply. The scholarship reflects the commitment of generous donors to invest in local students' educational goals.
Vocational & Trade Education Career / College Preparation Academic Scholarship Programs

William B. and Bonnie Z. Swonger Nursing Scholarship

The Community Foundation of Shelby County
Private
United States
US $1,250

The Community Foundation of Shelby County

Our Mission

To inspire donor generosity and transform it into meaningful, lasting impact through charitable gifts.

Our Vision

To be the primary partner for donors who want to advance the community’s quality of life and capacity for excellence.

William B. and Bonnie Z. Swonger Nursing Scholarship

A Shelby County resident who is a graduate of any high school within Shelby County and is pursuing a Registered Nursing degree. 

Selection based upon:

  • Financial need and academic ability.

Awards

  • Four $1,250 scholarships available
Nursing Career / College Preparation

Greg Legg NEPA Diamond Scholarship

Scranton Area Foundation Inc
Private
United States
Unspecified amount

Who We Are

Buiding a stronger, More Vibrant Community

For over 70 years, the Scranton Area Community Foundation has served Northeastern Pennsylvania as a steward of charitable resources, a grantmaker, and a catalyst for positive change. Guided by our core values of collaboration, trust, integrity, innovation, and inclusivity, we work to ensure that our communities thrive with opportunities for all.

This scholarship is awarded to a graduating senior from a high school in Lackawanna, Luzerne, Wayne, or Pike county who plays baseball and plans to continue playing in college.

Education - Higher Education Sports & Athletics Baseball & Softball

Champions for Change

The Aspen Institute Inc
Private
United States
Unspecified amount
The Champions for Change program, initiated by the Center for Native American Youth at the Aspen Institute, empowers Native youth through leadership opportunities. Founded in 2011, it selects 5-6 exceptional young leaders (ages 14-24) each year to inspire their communities and promote positive change. Participants engage in tailored advocacy training, fostering skills to create impactful stories from Indian Country, while all applicants join the CNAY network, enhancing their community involvement.
Native American Services Youth Development & Leadership

James P. & Mildred Gregg Zucco Scholarship

Northwest Connecticut Community Foundation
Private
United States
Approximately US $750
The James P. & Mildred Gregg Zucco Scholarship, offered by the Northwest Connecticut Community Foundation, supports graduating seniors from specific high schools who contribute to their school, church, or community. This scholarship awards an average of $750 to eligible students, with a focus on their dedication to local activities and service. It emphasizes the importance of community involvement and aims to assist students in their academic pursuits.
Career / College Preparation Academic Scholarship Programs Vocational & Trade Education

Ben J. Lipps Research Fellowship Program

American Society of Nephrology Foundation
Corporate
Central America, North America
Up to US $100,000
The Ben J. Lipps Research Fellowship Program supports nephrology fellows in conducting original research on kidney biology and disease. Each fellow receives $50,000 annually for up to two years, with a limit of two applications per sponsor per cycle. Candidates must hold an MD, DO, PhD, or equivalent and commit to 75% research time. The program encourages applications from underrepresented minorities in medicine, fostering diversity in nephrology research.
Kidney Diseases

Cinderella’s Closet of NEPA Scholarship

Scranton Area Foundation Inc
Private
United States
Unspecified amount

Who We Are

Buiding a stronger, More Vibrant Community

For over 70 years, the Scranton Area Community Foundation has served Northeastern Pennsylvania as a steward of charitable resources, a grantmaker, and a catalyst for positive change. Guided by our core values of collaboration, trust, integrity, innovation, and inclusivity, we work to ensure that our communities thrive with opportunities for all.

This scholarship is awarded to a female or female-identified student from a high school in Lackawanna, Luzerne, Pike, Susquehanna, Wayne, or Wyoming county who has 50 or more documented volunteer hours and and who has a GPA of 3.0 or higher.

Education - Higher Education Women & Girl Services Volunteerism & Philanthropy

ASN: Pre-Doctoral Fellowship Award Program

American Society of Nephrology Foundation
Corporate
Central America, North America
Up to US $60,000
The ASN Pre-Doctoral Fellowship Award Program aims to support PhD students conducting original research in kidney biology and disease. Each fellowship provides $30,000 annually for two years, contingent upon satisfactory progress reports. Eligible candidates must be graduate students in accredited programs, committed to kidney-focused research, and must engage with ASN as members. The program encourages applications from underrepresented groups in medicine, fostering diversity and innovation in nephrology research.
Kidney Diseases

Operating Grants for Nonprofits in South Dakota Highlights

Looking for operating grants for nonprofits in South Dakota?


Read more about each grant below or start your 14-day free trial to see all operating grants for nonprofits in South Dakota recommended for your specific programs.

Last updated: November 2, 2026. Next update: December 6, 2026.

Grant Insights : Operating Grants for Nonprofits in South Dakota

Grant Availability

How common are grants in this category?

Uncommon — grants in this category are less prevalent than in others.

100+ Operating grants for nonprofits in South Dakota grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

32 Operating grants for nonprofits in South Dakota over $25K in average grant size

25 Operating grants for nonprofits in South Dakota over $50K in average grant size

21 Operating grants for nonprofits in South Dakota supporting general operating expenses

92 Operating grants for nonprofits in South Dakota supporting programs / projects

2,000+ Grants on Instrumentl focused on Human & Social Services

2,000+ Grants on Instrumentl focused on Community Services

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Operating grants for Nonprofits in South Dakota?

Most grants are due in the first quarter.

Q1
35.5%
Q2
26.7%
Q3
18.3%
Q4
19.5%

Typical Funding Amounts

What's the typical grant amount funded for Operating Grants for Nonprofits in South Dakota?

Grants are most commonly $10,500.

$250 $250 Min.
$10,500 $10.5 K Median
$166,817 $166.8 K Average
$5,000,000 $5 M Max.

Average Grant Size

What's the typical amount funded for South Dakota?

Grants are most commonly $110,621.

$110,621

Total Number of Grants

What's the total number of grants in Operating Grants for Nonprofits in South Dakota year over year?

In 2024, funders in South Dakota awarded a total of 6,460 grants.

2022 6,268

2023 6,140

2024 6,460

Top Grant Focus Areas

Among all the Operating Grants for Nonprofits in South Dakota given out in South Dakota, the most popular focus areas that receive funding are Education, Human Services, and Philanthropy, Voluntarism & Grantmaking Foundations.

1. Education

2. Human Services

3. Philanthropy, Voluntarism & Grantmaking Foundations

Funding Over Time

How is funding for Operating Grants for Nonprofits in South Dakota changing over time?

Funding has increased by 17.48%.

2022 $638,830,994

2023 $606,495,212
-5.06%

2024 $712,509,384
17.48%

South Dakota Counties That Receive the Most Funding

How does grant funding vary by county?

Minnehaha County, Lake County, and Pennington County receive the most funding.

County Total Grant Funding in 2024
Minnehaha County $176,653,145
Lake County $117,647,066
Pennington County $90,630,616
Brookings County $75,457,854
Todd County $56,559,538