Upcoming Webinar
Instrumentl Fall Launch: Your Grant Operating System Has Leveled Up.
Wed, Nov 4 @ 2PM ET

Skip to main content
Main content

Best Large Grants for Nonprofit Organizations in Tennessee

Find the perfect Large Grants for Nonprofit Organizations in Tennessee on Instrumentl. 9,000+ Large Grants for Nonprofit Organizations in Tennessee in the United States.

9,000+

Available grants

$3.75B

Total funding

$5K

Median grant

9,000+ grants
$3.75B total
$5K median

Skip the search. Get matched with grants that fit your non-profit.

Skip the search.

Get matched with grants that actually fit.

Smart recommendations based on your profile — in minutes.

Find me grants

Filters

9,297 Results based on applied filters

Luke Horton & Justin Phillips Memorial Scholarship

Cherokee Nation Foundation
Association/Society
United States
Unspecified amount

Cherokee Nation Foundation

The Cherokee Nation Foundation is a nonprofit organization serving the Cherokee Nation, a federally recognized tribe of more than 470,000 citizens. Its mission is to provide educational opportunities to Cherokee students so they can reach their full potential. The Cherokee Nation Foundation is a tax-exempt charitable organization under Section 501(c)(3) of the Internal Revenue Code.

Scholarships

Cherokee Nation Foundation offers a diverse range of scholarships to help reverse the trend of rising student debt. Students may receive up to two CNF scholarships per academic year. All opportunities are reserved for Cherokee Nation citizens, unless otherwise noted in the description.

Luke Horton & Justin Phillips Memorial Scholarship

Applicant must be a Cherokee Nation citizen living inside or outside of the Cherokee Nation reservation. This scholarship is for general education with an emphasis on Information Technology and requires a minimum GPA of 2.0. It is for full-time students in undergraduate or graduate school or students going to vo-tech school.

Education - Higher Education Vocational & Trade Education

Reeves Foundation: Macular Degeneration Research Grant

Carl Marshall Reeves and Mildred Almen Reeves Foundation Grant
Private
United States
US $2,500 - US $125,000
The Reeves Foundation supports research aimed at understanding and treating macular degeneration, a condition that has personally affected the founder's family. Established in 1997, the foundation allocates 50% of its grants to research and the other half to local charities in Columbus, Indiana. Nonprofit organizations exempt under IRS code 501(c)(3) are eligible to apply, but funds cannot be used for administrative costs. The foundation prioritizes equipment purchases and partnerships with other funding sources.
Eye Diseases & Disorders

NIH Specialized Center Grant (Parent P50)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NIH Specialized Center Grant (Parent P50) aims to support multidisciplinary research programs with a specific scientific theme. Applicants must include an administrative core, research projects, and at least one resource core, demonstrating collaborative impact and synergy. This funding opportunity encourages innovative approaches to address major scientific objectives, fostering long-term research initiatives aligned with the NIH's mission. Applications should emphasize how their projects interconnect to achieve goals beyond individual efforts.
Health Facilities & Clinics

Achievement Annual Scholarship

CIRI Foundation
Private
United States
Up to US $10,000
The Achievement Annual Scholarship, offered by the CIRI Foundation, supports Alaska Native students pursuing higher education. This merit-based scholarship awards up to $8,000 for one academic year, covering direct educational costs and personal expenses. Applicants must maintain a minimum 3.0 GPA and be enrolled full-time in a 4-year undergraduate or graduate program. The scholarship aims to promote academic excellence and career development while honoring the cultural legacy of Alaska Natives.
Education - Higher Education Academic Scholarship Programs

Oneita J. Waltenberger Scholarship Fund

Dekalb County Community Foundation
Private
United States
Unspecified amount

Scholarship amounts vary depending on the scholarship applied for. Applicants are encouraged to apply for as many awards as they are eligible to increase the likelihood of receiving one or more awards.

Scholarships can be used for cost of attendance, direct education expenses, including tuition, books, and/or other school-related fees.

If you receive an award, be sure to complete your scholarship acceptance form (online portal). Scholarship awards are paid directly to the academic institution by the end of August.

Oneita J. Waltenberger Scholarship Fund

Established in 2015, this scholarship provides support to current or former residents of DeKalb County, IL, who are pursuing undergraduate or post-graduate education in the healthcare field. Current high school students, including high school seniors, do not qualify.

Education - Higher Education Medical Education & Professional Training

Jordan Fund Grant

Jordan Fund
Private
United States
Unspecified amount
The Jordan Fund, established by John & Kelly Olerud in 2003, is dedicated to supporting children with special needs and their families. This grant-making organization assists children with substantial disabilities up to age twenty-one, covering costs for respite, therapy, and essential equipment not provided by insurance. By funding 501(c)(3) organizations, the Jordan Fund aims to enhance the quality of life for these children and their families.
Children With Disabilities

Skin Cancer Pilot Research Grants

Skin Cancer Foundation
Private
Canada, United States
US $25,000 - US $50,000
The Skin Cancer Pilot Research Grants, funded by the Skin Cancer Foundation, support innovative studies in skin cancer prevention, detection, and treatment. With over $2 million awarded since 1981, these grants are aimed at early career dermatology investigators. Each year, researchers can apply for one-year projects, with a total of $125,000 available through two $50,000 grants and one $25,000 grant. This initiative is vital for advancing research and improving patient outcomes.
Skin Diseases & Dermatology Skin Cancers

Marion B. Sewer Distinguished Scholarship for Undergraduates

American Society For Biochemistry And Molecular Biology Inc
Association/Society
United States
US $2,000
The Marion B. Sewer Distinguished Scholarship for Undergraduates provides $2,000 to support students pursuing biochemistry and molecular biology, especially those from diverse backgrounds. Eligible applicants must be U.S. citizens or residents, enrolled full-time in accredited institutions, and members of ASBMB. This scholarship aims to enhance diversity in the biomedical workforce and encourage ongoing engagement in scientific activities. Applications are open to all qualified candidates, with a focus on underrepresented groups.
Molecular Biology Biochemistry

ASTRO Medical Student Fellowship Award for Underrepresented Populations

American Society For Radiation Oncology
Association/Society
United States
US $6,000
The ASTRO Medical Student Fellowship Award for Underrepresented Populations aims to enhance diversity in radiation oncology by supporting medical students from underrepresented backgrounds. Awardees receive a $6,000 package, including a stipend for an eight-week training program, funds for travel expenses, and mentorship opportunities. This initiative is part of ASTRO's broader mission to advance patient care and professional development in the field of radiation oncology, fostering an inclusive environment in medical education.
Cancer / Oncology

James P. Konieczka Memorial Scholarship

Saginaw Community Foundation
Private
United States
Unspecified amount

Scholarships

Since awarding our first $500 scholarship in 1987, the Saginaw Community Foundation has awarded college scholarships to area students totaling more than $13.7 million, thanks to our generous donors. Each year, over 500 college-bound or career and technical education students benefit from our scholarship awards.

Our single application process makes it easy to potentially qualify for one or more of our 260+ scholarships.

James P. Konieczka Memorial Scholarship

The James P. Konieczka Memorial Scholarship was established by his three children, Bryan, Amy, and Katie, to honor their father’s wishes after his passing in 2016 following a courageous year-long battle with cancer.

Jim believed in the value of a college education, but he also understood that not everyone wants to pursue this post-secondary education path. It was his wish that this scholarship be made available to someone seeking Career and Techincal Education (CTE) training or to someone seeking a traditional college degree.

Education - Higher Education Vocational & Trade Education

Warren Alpert Foundation: Distinguished Scholars Award

Warren Alpert Foundation
Private
United States
Unspecified amount
The Warren Alpert Foundation's Distinguished Scholars Award aims to enhance public health by funding innovative research in basic and clinical neurosciences. Nominations are invited from medical schools and research institutions in the U.S., focusing on candidates with a strong post-doctoral record. The selection process emphasizes scholarly achievements, scientific proposals, and letters of recommendation. A total of five awards will be granted to deserving scholars, fostering significant advancements in neuroscience.
Neuroscience

OSI Southern Cumberland Land Protection Fund

Open Space Institute Land Trust Inc.
Private
Chattooga County, Georgia, Cherokee County, Alabama +22 more
Unspecified amount
The OSI Southern Cumberland Land Protection Fund aims to protect vital forest habitats in Tennessee, Georgia, and Alabama, focusing on areas crucial for biodiversity and climate change adaptation. Launched in 2012, this fund has already safeguarded over 30,000 acres through grants, enhancing wildlife habitats and expanding recreational access. By supporting high-priority projects, it plays a significant role in conserving the rich ecological landscapes of the Southern Cumberland Plateau, ensuring the long-term viability of unique species.
Land / Habitat Conservation

AASM Foundation Disaster Relief Fund

American Academy Of Sleep Medicine Foundation
Private
American Samoa, Canada +5 more
Unspecified amount
The AASM Foundation Disaster Relief Fund, established in 2005, provides essential financial aid to AASM accredited sleep centers impacted by natural disasters. By supporting these centers, the fund ensures that medical care remains accessible to patients during crises. Past funding has assisted centers after events like Hurricane Katrina and the 2010 Haiti earthquake, helping them recover and restore operations quickly. This initiative highlights the commitment to maintaining patient care in the face of adversity.
Sleep Disaster Relief / Humanitarian Aid

Wehrli Custom Fabrication Scholarship Fund

Dekalb County Community Foundation
Private
United States
Unspecified amount

Scholarship amounts vary depending on the scholarship applied for. Applicants are encouraged to apply for as many awards as they are eligible to increase the likelihood of receiving one or more awards.

Scholarships can be used for cost of attendance, direct education expenses, including tuition, books, and/or other school-related fees.

If you receive an award, be sure to complete your scholarship acceptance form (online portal). Scholarship awards are paid directly to the academic institution by the end of August.

Wehrli Custom Fabrication Scholarship Fund

The Wehrli Custom Fabrication company created the scholarship to aid students interested in pursuing a career in the trades. The Fund supports two annual scholarships. The first is for a student attending a trade school or 2-year college, and the second benefits a student attending a 4-year college or university. Eligible areas of study include welding, machine tooling, auto mechanics, auto body, business management, and mechanical, industrial, manufacturing, or agricultural engineering.

Education - Higher Education Vocational & Trade Education

Esther Mae Nesbitt Medical Student Scholarship Fund

Dekalb County Community Foundation
Private
United States
Unspecified amount

Scholarship amounts vary depending on the scholarship applied for. Applicants are encouraged to apply for as many awards as they are eligible to increase the likelihood of receiving one or more awards.

Scholarships can be used for cost of attendance, direct education expenses, including tuition, books, and/or other school-related fees.

If you receive an award, be sure to complete your scholarship acceptance form (online portal). Scholarship awards are paid directly to the academic institution by the end of August.

Esther Mae Nesbitt Medical Student Scholarship Fund

This scholarship supports past or current Illinois residents who are either accepted for enrollment or currently enrolled as a full-time student at an approved college of medicine. Applicants must be U.S. citizens. Preference is given to female applicants and current or former residents of DeKalb County, IL.

Education - Higher Education Medical Education & Professional Training

Engagement Award: Convening Support

Patient-Centered Outcomes Research Institute
Association/Society
United States
Up to US $125,000
The Engagement Award: Convening Support fosters meaningful collaboration among patients, caregivers, clinicians, and other stakeholders in research. Initiated by the Patient-Centered Outcomes Research Institute (PCORI), this program aims to enhance patient engagement throughout the research process. By providing tools and resources, the award supports initiatives that improve healthcare delivery and outcomes, ensuring that patient perspectives are integral to research efforts.
Patient Care & Services

R3PEATS Rigor Scholar Cohort Awards (K12)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The R3PEATS Rigor Scholar Cohort Awards (K12) are designed to empower early-career researchers by enhancing their skills in rigorous scientific practices. This initiative promotes collaboration across institutions to develop best practices in research methodologies, including preregistration and randomization. Participants will gain essential training to ensure excellence and transparency in scientific research, aligning with the NIH's commitment to improve replicability and reproducibility in the field.
Education - Higher Education Medical Education & Professional Training

Henry C. McBay Faculty Research Fellowship

United Negro College Fund Inc
Private
United States
Up to US $18,000

United Negro College Fund

“A mind is a terrible thing to waste.”®

For more than seven decades, this principle has remained at the heart of UNCF, enabling us to raise more than $5 billion and help more than 500,000 students and counting not just attend college, but thrive, graduate and become leaders.

We do this in three ways: By awarding more than 12,000 students scholarships, worth more than $65 million, each year. By providing financial support to 37 historically Black colleges and universities (HBCUs). And by serving as the nation’s leading advocate for the importance of minority education and community engagement.

Henry C. McBay Faculty Research Fellowship

Dr. Henry Ransom Cecil McBay (May 29, 1914 – 1995) was an American chemist renowned for his excellence in teaching and mentorship. He received numerous awards for his commitment to encouraging disadvantaged students to pursue careers in the chemical sciences, including the American Chemical Society Award for Encouraging Disadvantaged Students into Careers in the Chemical Sciences.

The Henry C. McBay Faculty Research Fellowship is open to faculty members at UNCF member institutions and supports faculty-led research conducted in partnership with a student researcher or intern.

The fellowship provides:

  • Up to $15,000 to support faculty research in a field of the recipient’s choosing
  • Up to $3,000 to support a student researcher/intern
  • Total possible award: $18,000

All funded projects must be completed within one academic year and no later than Spring 2027.

Reporting Requirements

Each principal investigator is required to:

  • Submit a written final report on the research project at the end of Spring 2027
  • A published paper or submitted manuscript may be substituted for the final report
  • Submit a financial report detailing fellowship expenditures within six months of completing the grant

Education - Higher Education Academic Success & Enrichment

Batten Disease Clinical Research Consortium (BDCRC) Early Career Investigator Grant

Rare Diseases Clinical Research Network (RDCRN)
Federal Government
United States
Up to US $65,000
The Batten Disease Clinical Research Consortium (BDCRC) Early Career Investigator Grant aims to enhance the training of emerging clinician-scientists in rare disease research, particularly neuronal ceroid lipofuscinosis (NCL). This grant supports two post-graduate clinician investigators in conducting innovative research to improve care for individuals with NCLs. The program emphasizes the importance of community partnership, operational efficiency, and high-quality data to advance the development of new therapies and improve existing care standards.
Rare Diseases

EMF SAMFund Financial Assistance Grants

Expect Miracles Foundation
Private
United States
Up to US $19,000
The EMF SAMFund Financial Assistance Grants support young adult cancer survivors facing financial hardships due to their diagnosis. With 80,000 young adults diagnosed with cancer each year in the U.S., these grants provide critical assistance for essential living expenses like rent, car payments, and education. By prioritizing applicants who demonstrate financial need and articulate how the grant will aid their recovery, the program aims to alleviate financial toxicity and empower survivors to move forward with their lives.
Cancer / Oncology

Excellence Annual Scholarship

CIRI Foundation
Private
United States
Up to US $15,000
The Excellence Annual Scholarship, offered by the CIRI Foundation, supports full-time undergraduate and graduate students with a minimum GPA of 3.5. This merit-based scholarship recognizes academic excellence and community service, providing up to $10,000 for one academic year. Funding covers direct educational expenses and personal expenses, ensuring Alaska Native beneficiaries can pursue their educational and career aspirations while preserving their rich cultural heritage.
Education - Higher Education Academic Scholarship Programs

Sleep Research Program for Advancing Careers Grant

American Academy Of Sleep Medicine Foundation
Private
United States
Unspecified amount in in-kind support
The Sleep Research Program for Advancing Careers, funded by the American Academy Of Sleep Medicine Foundation, aims to develop early-career sleep scientists through a structured grant writing curriculum. Participants receive mentorship and training to submit competitive federal career development grants, such as NIH K awards. The program includes lectures and grant review sessions, ensuring applicants complete their proposals successfully. Additionally, a travel scholarship is offered for in-person meetings, fostering collaboration and growth in sleep research.
Sleep Medical Education & Professional Training

Dr. Philip H. and Esther J. Frandsen Scholarship

Community Foundation for Muskegon County
Private
United States
Unspecified amount

Community Foundation for Muskegon County

At the Community Foundation for Muskegon County, we work with donors, grantees, and advisors to address key community issues.

The mission of the Community Foundation is to engage donors and connect them with opportunities to make a lasting impact, build community endowment, provide leadership on key issues, and make grants that reflect the communities we serve.

Scholarships

Our scholarship funds seek to empower and encourage Muskegon County residents to pursue their dreams, hone in their gifts, and give back to our community.

If you’re a high school or homeschooled senior, current college student, early college senior, or adult learner, the Community Foundation for Muskegon County may have a scholarship for you. We manage one of the largest scholarship programs in our area, with over $1 million committed to students in over 500 new and renewed scholarships awarded each year.

Dr. Philip H. and Esther J. Frandsen Scholarship

This scholarship has been made possible by the generosity of Esther Frandsen, who established the Dr. Philip H. and Esther J. Frandsen Scholarship of the Community Foundation for Muskegon County. Esther Frandsen created the Dr. Philip H. and Esther J. Frandsen Scholarship Fund to provide scholarships for students from the Muskegon area who wish to train for careers in medicine or a medical related field. Mrs. Frandsen established the fund to honor the memory of her husband, Philip, who contributed so much to this community as a surgeon, and who worked tirelessly to improve the health of his patients through his surgical skills.

Education - Higher Education Medical Education & Professional Training

Dorothy Creason Tyler English Scholarship

Community Foundation for Muskegon County
Private
United States
Unspecified amount

Community Foundation for Muskegon County

At the Community Foundation for Muskegon County, we work with donors, grantees, and advisors to address key community issues.

The mission of the Community Foundation is to engage donors and connect them with opportunities to make a lasting impact, build community endowment, provide leadership on key issues, and make grants that reflect the communities we serve.

Scholarships

Our scholarship funds seek to empower and encourage Muskegon County residents to pursue their dreams, hone in their gifts, and give back to our community.

If you’re a high school or homeschooled senior, current college student, early college senior, or adult learner, the Community Foundation for Muskegon County may have a scholarship for you. We manage one of the largest scholarship programs in our area, with over $1 million committed to students in over 500 new and renewed scholarships awarded each year.

Dorothy Creason Tyler English Scholarship

This scholarship has been made possible by the generosity of the Tyler Family, who established the Dorothy Creason-Tyler English Scholarship of the Community Foundation for Muskegon County. This scholarship is intended for graduating seniors from North Muskegon High School, who have an aptitude and passion for English. The scholarship will be awarded to a student who has demonstrated overall academic achievement with a special interest in and passion for reading, writing and discussing the ideas generated from great literature.

Education - Higher Education Writing & Literature

Melvin Arthur Peters Memorial Scholarship

Community Foundation for the Fox Valley Region
Private
United States
Unspecified amount
The Melvin Arthur Peters Memorial Scholarship honors the legacy of Melvin Peters, a self-taught tradesman and entrepreneur from Shawano County. This scholarship supports high school seniors pursuing education in trades, reflecting Mel's commitment to hard work and skill development. Award amounts vary based on attendance costs, with disbursement in the first semester of college. Eligibility requires enrollment as a part-time or full-time student, emphasizing Mel's values of education and practical skills.
Academic Scholarship Programs Vocational & Trade Education

New Music Organization Fund Grant

New Music Usa Inc
Private
United States
Up to US $10,000
The New Music Organization Fund Grant supports non-profit organizations and performance groups dedicated to promoting new music and nurturing creators. This grant prioritizes artistic merit, community impact, immediate funding needs, and a commitment to inclusion. Eligible entities can apply for assistance to sustain their vital programming and resources for artists, ensuring the continued development of a vibrant music community.
Music

CIRI Foundation: Higher Education Scholarship

CIRI Foundation
Private
United States
Up to US $9,000
The CIRI Foundation offers the Higher Education Scholarship to support Alaska Native students pursuing post-secondary education. Scholarships provide $200 per credit hour for undergraduates and $400 for graduates, with a maximum of $9,000 per year. Eligible applicants must be CIRI shareholders or descendants, maintain a minimum 2.0 GPA, and be enrolled in accredited institutions. This initiative aims to enhance educational opportunities and promote cultural heritage.
Education - Higher Education Academic Scholarship Programs

Large Grants for Nonprofit Organizations in Tennessee Highlights

Looking for large grants for nonprofit organizations in Tennessee?


Read more about each grant below or start your 14-day free trial to see all large grants for nonprofit organizations in Tennessee recommended for your specific programs.

Last updated: November 2, 2026. Next update: December 6, 2026.

Grant Insights : Large Grants for Nonprofit Organizations in Tennessee

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

200+ Large Grants for Nonprofit Organizations in Tennessee grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

39 Large Grants for Nonprofit Organizations in Tennessee over $25K in average grant size

28 Large Grants for Nonprofit Organizations in Tennessee over $50K in average grant size

22 Large Grants for Nonprofit Organizations in Tennessee supporting general operating expenses

100+ Large Grants for Nonprofit Organizations in Tennessee supporting programs / projects

600+ Grants on Instrumentl focused on Food Access & Hunger

2,000+ Grants on Instrumentl focused on Human & Social Services

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Large grants for Nonprofit Organizations in Tennessee?

Most grants are due in the first quarter.

Q1
31.8%
Q2
22.5%
Q3
26.1%
Q4
19.6%

Typical Funding Amounts

What's the typical grant amount funded for Large Grants for Nonprofit Organizations in Tennessee?

Grants are most commonly $12,250.

$500 $500 Min.
$12,250 $12.3 K Median
$74,557 $74.6 K Average
$2,300,000 $2.3 M Max.

Average Grant Size

What's the typical amount funded for Tennessee?

Grants are most commonly $122,522.

$122,522

Total Number of Grants

What's the total number of grants in Large Grants for Nonprofit Organizations in Tennessee year over year?

In 2024, funders in Tennessee awarded a total of 44,541 grants.

2022 39,759

2023 39,873

2024 44,541

Top Grant Focus Areas

Among all the Large Grants for Nonprofit Organizations in Tennessee given out in Tennessee, the most popular focus areas that receive funding are Education, Human Services, and Philanthropy, Voluntarism & Grantmaking Foundations.

1. Education

2. Human Services

3. Philanthropy, Voluntarism & Grantmaking Foundations

Funding Over Time

How is funding for Large Grants for Nonprofit Organizations in Tennessee changing over time?

Funding has increased by 25.17%.

2022 $3,809,568,961

2023 $4,350,973,827
14.21%

2024 $5,446,107,598
25.17%

Tennessee Counties That Receive the Most Funding

How does grant funding vary by county?

Shelby County, Davidson County, and Knox County receive the most funding.

County Total Grant Funding in 2024
Shelby County $2,664,074,547
Davidson County $1,298,691,246
Knox County $294,292,803
Hamilton County $283,062,013
Henderson County $215,691,648