Best Large Grants for Nonprofit Organizations in Tennessee

Armstrong County Community Foundation

The Armstrong County Community Foundation, a public nonprofit corporation,

• Gives grants, scholarships, and organizational support to address the needs of our community.
• Builds a permanent endowment to help our donors create a legacy through this endowment.
• Promotes informed philanthropy to increase and sustain charitable resources for the region.
• Provides leadership and builds partnerships to identify and solve community issues.

Quality Life Services Healthcare Career Scholarship Fund

Quality Life Services has a long history of providing quality healthcare in Western Pennsylvania. In 1973, Kenneth R Tack Sr. and his sons Philip E. Tack and Kenneth R Tack Jr. founded Sugar Creek Rest in Worthington, PA. Quality Life Services has since expanded to include Chicora Medical Center in Chicora, PA; Trinity Living Center in Grove City, PA; Countryside in Mercer, PA; South Fayette Nursing Center in Markleysburg, PA; Henry Clay Villa in Markleysburg, PA; West Haven Manor in Apollo PA; Golden Hill Nursing and Rehab in New Castle, PA; Quality Pharmacy in Chicora, PA; and Fair Winds Manor in Sarver, PA.

Since its origination, Quality Life Services has been committed to providing exceptional healthcare services and career opportunities to thousands of people in our community. As a way of continuing that commitment to quality care and saying thanks to those who have helped to provide it, a scholarship has been established for current employees’ children and grandchildren who are pursuing a career in healthcare.

Scholarship Details

• Available to High School Seniors
• Nonrenewable

All ACCF Scholarships are merit based.

The FY26 Spinal Cord Injury Research Program (SCIRP) Investigator-Initiated Research Award (IIRA) supports innovative research aimed at enhancing patient care and quality of life for individuals with spinal cord injuries. This award encourages collaboration, allowing an Early-Career Partnership Option for two Principal Investigators, where one must be an early-career investigator. Focused on impactful research from basic to translational science, this opportunity is crucial for advancing SCI knowledge and interventions.

The FY26 Spinal Cord Injury Research Program Clinical Trial Award supports innovative clinical trials aimed at significantly improving spinal cord injury treatment. This funding opportunity encourages collaboration by allowing two Principal Investigators, including an early-career investigator, to drive the research forward. Applicants must partner with at least two SCI community members, ensuring that the project is informed by lived experiences and community needs throughout its development and implementation.

The FY26 Spinal Cord Injury Research Program Clinical Translation Research Award funds innovative clinical research aimed at bridging the gap to larger clinical trials. It focuses on accelerating the application of new techniques and improving patient outcomes through effective diagnosis and rehabilitation strategies. Key features include an Early-Career Partnership Option for principal investigators and a requirement for community partner involvement, ensuring collaborative research that meets real-world needs.

The BRAIN Initiative seeks to develop innovative tools and approaches for neuroscience research, focusing on cell-specific and circuit-specific processes within the central nervous system. This initiative encourages projects that enhance our understanding of brain architecture and function through novel technologies for characterizing neural components and advancing methods for recording and modulating neural activity. Applications are invited to address significant challenges and promote transformative breakthroughs in neuroscience.

The DoW Spinal Cord Injury Translational Research Award supports innovative research to transform promising spinal cord injury findings into clinical applications. It features an Early-Career Partnership Option, requiring at least one early-career principal investigator. Collaborations with SCI community partners are essential for providing guidance throughout the project. This funding opportunity aims to enhance the effectiveness of spinal cord injury interventions and improve patient outcomes.

Betsy L. Bertoli Scholarship

Academic Focus:

• Accounting or business administration/management

Award Average:

• $250

For Torrington High School graduating seniors who plan to pursue a career in accounting or business administration/management at the university level and have had at least one successful high school semester of accounting.

The Edna Mae Scholarship, offered by the Community Foundation of Southern New Mexico, aims to support women from rural communities in their pursuit of higher education at vocational community colleges or universities. This scholarship is open to applicants actively enrolled in any form of higher education, including undergraduate and vocational programs, with a special focus on assisting those in need. Applicants must be graduating high school seniors or currently enrolled students.

The Alexandra Armstrong Innovation Grant, offered by the Foundation for Financial Planning, recognizes nonprofits that demonstrate exceptional creativity and impact in pro bono financial planning services. Established in honor of Alexandra Armstrong, a dedicated advocate for community service and financial planning, this grant aims to expand access to vital financial advice for underserved populations. Eligible organizations can apply annually to receive funding that supports innovative programs designed to enhance financial well-being.

The Scheidel Foundation offers Integrative Cancer Care Grants aimed at enhancing the quality of life for individuals living with cancer. This initiative supports organizations that promote awareness and adoption of integrative practices, targeting both the medical community and patients. The Foundation seeks proposals that foster long-term solutions and innovative programs, focusing on evidence-based information and practices. Grants are available through a selective process, emphasizing transformative impacts in the field.

Marion Community Foundation

Since 1998, area residents have been turning to Marion Community Foundation to make their philanthropic giving as effective as possible. We are a public charity serving thousands of people who share a common concern … improving the quality of life in Marion County. We use distributions from the more than 500 charitable funds — created by generous, local donors — to award more than $2.5 million in grants and scholarships each year to many of the humanitarian, educational and cultural organizations in this remarkable community we call home.

Marion Community Foundation is the area’s leading philanthropic organization, providing charitable donors the opportunity to easily create endowment funds to benefit and support our community through grants and scholarships. We serve communities throughout Marion County through philanthropy, leadership, and civic engagement.

Alex Masters Memorial Scholarship

Following the unexpected passing of their son, Alex Masters, a memorial scholarship fund was created at the River Valley Education Foundation by Randy and Kathy Masters and Morgan Masters Quickel, Alex’s sister. In 2013, the fund was migrated to Marion Community Foundation and became the Alex Masters Memorial Scholarship Fund.

Alex never knew a stranger and loved to discuss and debate any subject with others. He loved baseball and football, was an avid reader, and was pursuing a career in medicine. But, perhaps his biggest love—outside of his family—was his love for music. It is his family’s hope that his song will live on through this scholarship.

The fund honors Alex’s memory and supports the educational goals of graduating seniors from River Valley High School. According to Kathy, the family created the scholarship with the intention of supporting those who have encountered adversity and to overcome and cope with life’s challenges through education.

Marion Community Foundation

Since 1998, area residents have been turning to Marion Community Foundation to make their philanthropic giving as effective as possible. We are a public charity serving thousands of people who share a common concern … improving the quality of life in Marion County. We use distributions from the more than 500 charitable funds — created by generous, local donors — to award more than $2.5 million in grants and scholarships each year to many of the humanitarian, educational and cultural organizations in this remarkable community we call home.

Marion Community Foundation is the area’s leading philanthropic organization, providing charitable donors the opportunity to easily create endowment funds to benefit and support our community through grants and scholarships. We serve communities throughout Marion County through philanthropy, leadership, and civic engagement.

Allen “Bus” Augenstein Memorial Scholarship

Originally the Claridon Alumni Association Scholarship Fund, this endowment (created in 2021), was renamed in 2023 to honor the late Allen ‘Bus’ Augenstein. The scholarship supports seniors and graduates of River Valley High School, with special consideration for students who pursue an education in the fields of engineering, health care, or education (especially science education). Awards also favor students active in band, choir, FFA, or school sports, especially golf and cross country.

Allen lived in Marion for more than 90 years. His father, A.B. Augenstein, served as Superintendent of Claridon Schools and River Valley School District, 1960–1965, and is well remembered for, among other accomplishments, starting football (6 man) in the district. His mother, Hazel, taught mathematics at Claridon during World War II.

Marion Community Foundation

Since 1998, area residents have been turning to Marion Community Foundation to make their philanthropic giving as effective as possible. We are a public charity serving thousands of people who share a common concern … improving the quality of life in Marion County. We use distributions from the more than 500 charitable funds — created by generous, local donors — to award more than $2.5 million in grants and scholarships each year to many of the humanitarian, educational and cultural organizations in this remarkable community we call home.

Marion Community Foundation is the area’s leading philanthropic organization, providing charitable donors the opportunity to easily create endowment funds to benefit and support our community through grants and scholarships. We serve communities throughout Marion County through philanthropy, leadership, and civic engagement.

Andrew Wigton Memorial Scholarship

Andrew Wigton lost his young life in an automobile accident during his senior year at Pleasant High School. His parents and family created this scholarship in 2006 to honor his memory. Special consideration is given to applicants who have been members of the varsity basketball or varsity soccer team, two sports that Andrew loved.

In addition to memorial contributions, this fund is supported by the proceeds of the Dre 5K Run and a golf outing and by Andrew’s parents, friends, and family members.

Seniors of Pleasant High School in the upper 25th percentile of the graduating class are the focus of the Andrew Wigton Memorial Scholarship.

Armstrong County Community Foundation

The Armstrong County Community Foundation, a public nonprofit corporation,

• Gives grants, scholarships, and organizational support to address the needs of our community.
• Builds a permanent endowment to help our donors create a legacy through this endowment.
• Promotes informed philanthropy to increase and sustain charitable resources for the region.
• Provides leadership and builds partnerships to identify and solve community issues.

James K. Greenbaum Scholarship

In gratitude for the many years of service that Dr. Greenbaum has given to our community, a scholarship has been established in his name to benefit a graduating student from the area who will be furthering his or her education.

The goal of the scholarship is to honor Dr. Greenbaum’s lifetime contribution to the children of our area and to continue his legacy.

Scholarship Details

• Available to High School Seniors
• Nonrenewable

All ACCF Scholarships are merit based.

The NIAID aims to enhance infectious disease research by supporting human microphysiologic systems (MPS) development. These in vitro platforms mimic human tissue functions, promoting drug and biological product development while reducing animal use. This initiative aligns with NIH’s commitment to innovative research practices and regulatory acceptance. By focusing on MPS in infectious disease contexts, NIAID seeks to streamline therapeutic advancements and establish robust human tissue models, addressing critical challenges in understanding and treating infections.

Marion Community Foundation

Since 1998, area residents have been turning to Marion Community Foundation to make their philanthropic giving as effective as possible. We are a public charity serving thousands of people who share a common concern … improving the quality of life in Marion County. We use distributions from the more than 500 charitable funds — created by generous, local donors — to award more than $2.5 million in grants and scholarships each year to many of the humanitarian, educational and cultural organizations in this remarkable community we call home.

Marion Community Foundation is the area’s leading philanthropic organization, providing charitable donors the opportunity to easily create endowment funds to benefit and support our community through grants and scholarships. We serve communities throughout Marion County through philanthropy, leadership, and civic engagement.

Aris Kasotis Memorial Scholarship

Aris Kasotis was a young man who liked to see people included. “He made friends easily,” said his mother, Joan Kasotis, Marion County Auditor, “and he liked to make sure that no one was overlooked.”

Aris’ enjoyment of life and his desire to share with others prompted his parents, Joan and long-time local restaurateur and caterer, George Kasotis, to establish a memorial scholarship in Aris’ name following his untimely death in an automobile accident. More than 100 memorial contributions from friends and family helped to establish this scholarship fund in 2007.

The Kasotis Fund provides an annual scholarship for a senior from Marion Harding High School who ranks in the upper 50 percent of his or her senior class, but not the top 10 percent. Special consideration is given to applicants who have participated in Harding Singers, interscholastic wrestling, and/or interscholastic football—school activities that Aris enjoyed.

The Indian Land Tenure Foundation (ILTF) offers a Cultural Awareness Grant aimed at revitalizing the cultural and spiritual values related to Indian land. This initiative supports American Indian nations in enhancing their ties to the land, which is vital for traditional practices and beliefs. Eligible entities include tribal governments and 501(c)(3) nonprofit organizations. Ineligible activities encompass advocacy efforts, land purchases, and direct funding to individuals, ensuring resources focus on community-centered cultural preservation.

The North Central Soybean Research Grant Program (NCSRP) aims to enhance soybean production through collaborative research and outreach. By investing in innovative projects, it addresses key challenges in soybean yield, profitability, and environmental sustainability. The program encourages proposals that focus on genetic improvement, pest control, and production practices tailored for the North Central region. Funded projects are expected to deliver practical benefits to soybean farmers while fostering communication and collaboration among stakeholders in the industry.

The Donaghue Foundation's Another Look Grant focuses on enhancing health and well-being for older adults in long-term care facilities. It prioritizes research that utilizes existing datasets and includes stakeholders to inform project development. High-priority topics include improving palliative care, workforce innovations, and addressing disparities in care quality. This program is open to PhD investigators from tax-exempt institutions in the U.S., aiming to foster impactful health-related research that enhances care quality for seniors.

The Allen Foundation Grant supports initiatives that enhance human nutrition through research, education, and training. It prioritizes projects that develop nutritional programs, including mandatory nutrition courses in medical schools and sustainable food systems. Eligible applicants must be U.S.-based non-profits or governmental entities with a focus on nutrition education and research. The foundation encourages proposals that include matching funds and has specific criteria for academic research and budgetary self-sufficiency.

The SCI Research on the Translational Spectrum (SCIRTS) portfolio aims to promote innovative research that enhances function and alleviates complications following spinal cord injuries. It encourages studies that involve individuals with SCI, emphasizing translational significance in research designs. SCIRTS grants support diverse research areas, including mechanistic, preclinical, and clinical studies, to develop effective interventions. Funding categories include Postdoctoral Fellowships, Pilot Research Grants, and Senior Research Grants, targeting early-career and senior investigators to advance spinal cord injury research.

About CKCF

Our Mission

Central Kentucky Community Foundation is the philanthropic focal point in the region, serving as a resource, leader and catalyst to people who wish to improve life in their community.

Available Scholarships

2026 Rylee Marie Razon Memorial Equine Scholarship

The Luce Indigenous Knowledge Fellowship, launched by the First Nations Development Institute and the Henry Luce Foundation, supports Native knowledge holders and makers in their transformative work. With ten fellowships of $75,000 each, this two-year program fosters growth and collaboration across diverse fields such as agriculture, climate change, and cultural revitalization. Fellows will engage in community-building through required convenings, enhancing their leadership skills and professional networks to benefit Native communities.

The American Cancer Society's Mentored Research Grants for Postdoctoral Fellowships (PF) aim to support emerging researchers in their training programs, fostering their transition to independent cancer research careers. Eligible candidates include US citizens or non-citizens with valid visas who have completed their doctoral degrees within the last four years. The fellowship offers funding for up to three years, with stipends of $66,000 to $70,000 annually, alongside allowances for health insurance and professional development.

The Clinician Scientist Development Grant (CSDG) by the American Cancer Society supports full-time faculty aiming to become independent clinician scientists while maintaining clinical practice. Eligible applicants must hold a doctoral degree, an active clinical license, and have clinical care experience. The grant provides funding of $135,000 annually for 3 to 5 years, including allowable indirect costs, to advance cancer research in key priority areas.

The American Cancer Society (ACS) and the American Society for Radiation Oncology (ASTRO) co-fund the Clinician Scientist Development Grant (CSDG), aimed at advancing the research careers of clinician scientists in radiation oncology. Eligible applicants are full-time faculty members at U.S. institutions with a doctoral degree and an active clinical license. The grant supports research for 3 to 5 years, providing $135,000 annually for direct costs, plus allowable indirect costs, while encouraging diversity in applications.

The Mission Program Grants: New Worshiping Communities Seed Grant offers up to $10,000 to support the establishment of new worshiping communities connected to the Presbyterian Church (USA). These grants focus on covering initial operational costs for the first year, including salaries and educational materials. Eligible applicants must be newly formed communities established after July 2010, located in the U.S. or Puerto Rico. This initiative fosters community growth rather than expanding existing congregations.