Infrastructure and Workforce Grants for Appalachia from ARC
Nonprofit organizations, public agencies, tribes, and higher education institutions in eligible Appalachian counties in North Carolina can seek funding to improve critical infrastructure and strengthen business and workforce development. The Appalachian Regional Commission’s Area Development Program supports projects like water and wastewater systems, transportation, broadband, entrepreneurship, worker training, and related community capacity-building across the region.
Appalachian Regional Commission
Community Impact Grants for Nonprofits from Triangle Community Foundation
Nonprofit organizations working on community well-being, youth enrichment, or education in North Carolina and other Clancy & Theys regions can apply for grants up to US $10,000 to strengthen local services and quality of life. North Carolina healthcare access and related social service programs may be eligible for support from Triangle Community Foundation’s Clancy & Theys 1949 Fund.
Triangle Community Foundation
North Carolina Youth Services Funding via Dan Paul Foundation
Nonprofit 501(c)(3) organizations supporting youth health, education, and welfare in North Carolina can seek up to US $15,000 for direct-service programs. The Dan Paul Foundation supports child advocacy, homelessness and poverty services, early childhood development, environmental education, and refugee enrichment, which may benefit healthcare-related initiatives serving children and youth.
The Dan Paul Foundation
North Carolina Economic Empowerment Funding via Cisco Systems Foundation
Nonprofit and nongovernmental organizations using technology for crisis response, education access, or economic empowerment projects that serve mostly economically underserved communities, including in North Carolina, can apply for Global Impact Cash Grants, with awards up to US $100,000. Grants from Cisco Systems Foundation help innovative, tech-enabled programs scale impact through early-stage solution development.
Cisco Systems Foundation
Good Neighbor Citizenship Company Grants
State Farm's Good Neighbor Citizenship Company Grants aim to enhance community safety, development, and education. Focused on long-term impact, they support initiatives in auto and home safety, disaster preparedness, affordable housing, and educational programs. Eligible recipients include nonprofits, educational institutions, and government entities. However, funding is not available for individuals, religious programs, or organizations outside the U.S. By addressing critical community needs, these grants foster safer and more resilient neighborhoods.
State Farm Companies Foundation
Community and Education Funding from Amgen Foundation
Nonprofit organizations and eligible public or governmental entities supporting humanitarian, social, education, or community programs in North Carolina or nationwide can seek non-healthcare donations and sponsorships for charitable initiatives. With a mission to strengthen communities, Amgen Foundation provides funding to U.S.-based 501(c)(3) charities and similar qualified organizations, which may benefit nonprofits that also operate healthcare-related community programs.
The Amgen Foundation Inc
Obici Healthcare Foundation Grants for North Carolina Health Programs
Nonprofit 501(c)(3) organizations and public entities improving community health in North Carolina’s Gates County can seek US $500 - US $5,000 for programs that boost wellness, physical activity, health awareness, or access to critical resources. Focused on community health, Obici Healthcare Foundation invites collaborative, innovative projects; applications are accepted on a rolling basis until funds are exhausted.
Obici Healthcare Foundation
PNC Foundation: Foundation Grant
The PNC Foundation aims to enhance the lives of individuals in local communities through partnerships with nonprofit organizations. Their focus includes promoting educational opportunities, particularly for early childhood education, and supporting economic development initiatives. Grants are available for organizations that benefit low- to moderate-income families and enhance community growth. The foundation prioritizes programs that foster sustainability and diversity, ensuring a lasting impact on the communities they serve.
PNC Foundation
Roche Corporate Donations and Philanthropy (CDP)
Roche Corporate Donations and Philanthropy (CDP) focuses on impactful projects that foster sustainable development, engage employees, and leverage Roche's expertise. Their philanthropic efforts prioritize humanitarian, educational, environmental, and cultural initiatives, aiming to build stronger communities and support innovative projects. Eligibility is limited to local organizations, while ineligible projects include those with political or religious ties. The foundation strives to create a positive societal impact through collaboration and strategic partnerships.
La Roche, Inc.
State Employees Credit Union Foundation Support for Healthcare
Nonprofit and governmental organizations in North Carolina seeking funding for high-impact healthcare, housing, education, or human services projects can apply for SECU Foundation grants. Focused on capital, programmatic, and capacity-building initiatives, the State Employees Credit Union Foundation favors tangible projects with regional or statewide reach that strengthen communities and public employees.
State Employees Credit Union Foundation
North Carolina Health Funding via Sidney Stern Memorial Trust
North Carolina nonprofit healthcare and health access programs can access funding through the Sidney Stern Memorial Trust for charitable, medical, scientific, or educational work benefiting U.S. communities. Eligible applicants are 501(c)(3) organizations with tax-exempt status; funded activities must occur within the U.S. and demonstrate broad, meaningful impact on their target populations.
Sidney Stern Memorial Trust
The Bank of America Foundation Sponsorship Program
The Bank of America Foundation Sponsorship Program aims to enhance economic mobility and social progress in low- and moderate-income communities through partnerships with nonprofit organizations. This initiative focuses on critical areas such as workforce education, basic needs like food and housing, and community development. The Foundation invested $350 million last year and encourages employee volunteerism and giving, supporting nonprofits in various sectors, including arts, culture, and diversity initiatives.
Bank Of America Charitable Foundation Inc
NC Dental Foundation: Dental Public Health Award
Applications due Aug 31, 2026
The N.C. Dental Society Foundation announces the Dental Public Health Award, offering $1,500 to deserving organizations at the Fall 2023 Education Conference. Eligible nominees include tax-exempt nonprofits or government agencies committed to improving oral health outcomes, access to dental services, and public education on preventative practices. Self-nominations are encouraged. Note that past recipients from 2022 must wait until 2024 to apply.
North Carolina Dental Society Foundation
NC Dental Foundation: Endowment Grant Program
Applications due Aug 31, 2026
The North Carolina Dental Society Foundation is launching its Endowment Grant Program to support oral health initiatives across North Carolina. Up to four qualifying nonprofit organizations will receive $5,000 each to enhance dental care accessibility and improve health outcomes for both children and adults. Eligible applicants include tax-exempt nonprofits and government agencies dedicated to fostering oral health education and services.
North Carolina Dental Society Foundation
GSK IMPACT Awards: North Carolina
Full proposal due Sep 5, 2026
The GSK IMPACT Awards in North Carolina honor outstanding nonprofit organizations making a significant impact on community health. This annual program, in partnership with the Triangle Community Foundation, recognizes up to ten organizations for their exemplary contributions to health and wellness. Applicants must demonstrate a commitment to improving community health through innovative and effective programs. Eligible organizations must operate in the Triangle area and meet specific criteria regarding revenue and community impact.
GlaxoSmithKline
Walnut Cove Members Association Grants for Healthcare
Applications due Sep 25, 2026
Nonprofit 501(c)(3) organizations serving Western North Carolina residents with social or healthcare services can seek US $10,000 - US $25,000 for programs addressing basic needs like food, shelter, and health care. Walnut Cove Members Association also supports youth education and certain natural, cultural, or animal welfare initiatives benefiting low-income communities.
Walnut Cove Members Association Inc
Health and Human Services Funding from Robinson Foundation
Applications due Oct 15, 2026
Nonprofit 501(c)(3) organizations providing medical assistance, health services, or related support in North Carolina and the broader Southern region can seek funding for single-year projects. Grants from Robinson Foundation help established charities (3+ years) addressing health, poverty relief, children and families, veterans, disaster relief, and related humanitarian needs, excluding capital projects.
Robinson Foundation
Youth and Basic Needs Funding from TJX Foundation
Letter of inquiry due Oct 31, 2026
Nonprofit 501(c)(3) organizations near TJX locations in North Carolina can apply for TJX Foundation grants to support basic needs, youth education, workforce readiness, and safety from domestic violence. Eligible health-related programs serving vulnerable families and children may benefit, provided they meet the mission, distance, and nondiscrimination requirements and have not received TJX funding in the past year.
The Tjx Foundation Inc
Lawrence Foundation Grant
Applications due Nov 1, 2026
The Lawrence Foundation is a private family foundation established in 2000, dedicated to granting funds for environmental and human services causes. Eligible organizations include 501(c)(3) nonprofits and public schools, with grants typically ranging from $5,000 to $10,000. The foundation supports unrestricted grants for various projects, including disaster relief and environmental programs, but does not fund individuals or for-profit entities. Applications are evaluated based on alignment with the foundation's priorities.
Lawrence Foundation
Healthcare and Community Funding for Carolinas Nonprofits via Van Every Foundation
Full proposal due Nov 10, 2026
Nonprofit 501(c)(3) organizations in North Carolina seeking support for healthcare, rehabilitation, human services, education, or arts projects and capital needs may be eligible for grants of US $10,000 - US $50,000 from the Philip L Van Every Foundation. Focus areas include health care access and delivery, wellness, prevention, substance abuse, and medical rehabilitation in North and South Carolina.
Philip L Van Every Foundation
Max and Victoria Dreyfus Foundation Grant
Applications due Nov 11, 2026
The Max and Victoria Dreyfus Foundation offers grants to support diverse initiatives, including museums, educational programs, and environmental activities. Aiming to make a significant impact with modest funding, the Foundation targets IRS-qualified non-profits in the U.S. Grants typically range from $1,000 to $20,000, fostering community development and enhancement. Organizations focused on youth, seniors, and individuals with disabilities are particularly encouraged to apply, as the Foundation seeks to empower those in need.
Max and Victoria Dreyfus Foundation
Duke Endowment Child Welfare Grants in North Carolina
Pre proposal due Dec 15, 2026
Grants from The Duke Endowment help North Carolina child- and family-serving nonprofits fund implementation support for evidence-based programs addressing child abuse, neglect, and family well-being. Accredited organizations with two years of audited financials, including residential and foster care providers, may apply through a required pre-application process; South Carolina agencies are also eligible.
The Duke Endowment
Camber Foundation Grants for North Carolina Health
Applications due Feb 27, 2027
Nonprofit 501(c)(3) organizations and fiscally sponsored programs improving health and wellness in Eastern North Carolina can apply for US $25,000 - US $50,000 grants to support healthcare access, mental health, and related services. Camber Foundation also funds education, workforce development, entrepreneurship, and digital opportunity through one-year general operating or program-specific awards.
Camber Foundation
O'Reilly Automotive Foundation Grant
Applications due Apr 15, 2027
The O'Reilly Automotive Foundation Grant focuses on enhancing community welfare through philanthropic initiatives that support economic stability, workforce development, health services, and disaster relief. Established in 2020, the Foundation seeks to empower underrepresented individuals and organizations in the U.S. by addressing vital community needs. It particularly aims to provide assistance to nonprofits that foster positive change and improve quality of life for those in need, ensuring a lasting impact in local communities.
O'Reilly Automotive Foundation Inc
Health and Human Services Funding from Underdown Family Foundation
Applications due Apr 30, 2027
Nonprofit 501(c)(3) organizations providing health, human services, education, or faith-based programs in Hickory, North Carolina can seek support to enrich the local community. Grants from Underdown Family Foundation help North Carolina healthcare and related service providers address community needs, with a strong preference for projects maximizing impact in the Hickory area.
Underdown Family Foundation
Nantahala Health Foundation Support for Youth Well-Being
Pre proposal due May 30, 2027
Nonprofit organizations, government units, tribal governments, and eligible businesses in western North Carolina can seek funding to launch, grow, or scale youth and young adult well-being programs. With a mission to improve regional health, Nantahala Health Foundation provides North Carolina healthcare and education initiatives up to US $50,000, prioritizing underserved youth and collaborative partnerships.
Nantahala Health Foundation
Gupta Family Foundation Grant
Applications due Jul 31, 2027
The Gupta Family Foundation Grant aims to empower disadvantaged individuals by providing financial support to organizations that foster self-reliance. Headquartered in Herndon, Virginia, the foundation offers grants ranging from $5,000 to over $250,000, prioritizing smaller organizations with a strong commitment to their missions. Eligibility typically includes US-based IRS 501(c)(3) entities, with operations extending to countries like India and Kenya. The foundation emphasizes mission alignment and effective resource allocation to ensure maximum impact.
Gupta Family Foundation