Best Large Grants for Nonprofit Organizations in Wisconsin

Bristol Myers Squibb is dedicated to enhancing healthcare and advancing scientific knowledge through its Corporate Giving program. By supporting various organizations, BMS aims to improve health equity and access to essential medicines for underserved populations. Their focus includes charitable donations, medical education, and community support initiatives. This commitment reflects BMS's goal to make a positive impact on patients' lives and foster strong communities where their employees work and live.

Homeless Case Management Services Grant (HCMS)The Homeless Case Management Services (HCMS) grant provides intensive case management services to eligible families experiencing homelessness. The program is funded through the Temporary Assistance for Needy Families (TANF) block grant program and created through Wisconsin Act 59, statue §16.3085. All HCMS funds must be administered in accordance with applicable TANF requirements, rules, and regulations.

HCMS supports shelter facilities and motel voucher programs serving families experiencing homelessness. ​The HCMS program helps eligible families experiencing homelessness receive intensive case management services designed to support housing stability. Services focus on practical areas that can help families move towards stability.

The MCW-Led Momentum Grant, offered by the Advancing a Healthier Wisconsin Endowment, supports collaborative teams in pursuing innovative research and programs to enhance Wisconsin's health workforce. With funding up to $250,000, the grant aims to address critical health needs and promote health equity across diverse communities, ensuring impactful outcomes during the project period.

The NCR-SARE Youth Educator Grant Program supports educators in the North Central Region to innovate ways of teaching sustainable agriculture. With funding up to $6,000, this program encourages educators to engage youth and promote sustainable practices. By sharing their experiences, grantees can create a ripple effect among peers, enhancing the reach and impact of sustainable agriculture education. This initiative aims to foster creativity and collaboration in teaching sustainable practices to the next generation.

The Windgate Charitable Trust Grant supports contemporary craft and visual arts in the U.S. It offers funding for fellowships, residencies, educational outreach, and materials for craft programs. The foundation prioritizes strengthening visual arts in colleges and expanding K-12 art-integrated programs, providing opportunities for artists and educators to enhance their skills and foster creativity among students. Organizations with previous funding from Windgate can apply through the grantee portal.

The Andersen Corporate Foundation, established in 1941, aims to enhance lives and strengthen communities where its employees reside. It has contributed over $65 million to various causes, focusing on housing, healthcare, hunger relief, and education. Grants range from $5,000 to $50,000, primarily supporting nonprofit organizations that align with these areas, particularly in communities where Andersen operates, ensuring a lasting impact on local initiatives.

Who We Are

Advancing Wisconsin to be the healthiest state in the nation

AHW provides funding and resources to researchers, organizations, and communities devoted to improving the health of the people of Wisconsin.

Call for Applications:

MCW Academic Partners for Community-Led Seed Grants

AHW is seeking eligible MCW faculty ready to serve as MCW academic partners with pre-defined key roles on funded Community-Led Seed Grants based on the community-identified need for the academic partner and the MCW faculty member’s interest and expertise. AHW’s Community-Led Seed Grants support community-led project teams to address community-identified and community-prioritized health needs through conducting initial exploration and testing innovative ideas to serve as a foundation for future sustainable efforts to improve health and health equity in Wisconsin’s communities. Community-Led Seed Grant applications are submitted independently by eligible community partners and projects approved for funding will be completed during a 12-month period, beginning Jan. 1, 2027, with an optional six-month no cost extension.

The MCW faculty should be able to commit 10% or 20% FTE at the time of funding to engage with one or two Community-Led Seed Grant projects.

The Fence Authority Scholarship offers a $1,000 award to students pursuing a bachelor’s degree in fields that enhance community beautification, such as architecture, civil engineering, and environmental sciences. Applicants must be U.S. citizens, enrolled full-time, and involved in community service. This scholarship aims to empower students to contribute positively to society while furthering their education in impactful disciplines.

The CoVantage Cares Foundation Grant supports non-profit organizations in Wisconsin, Michigan, and Illinois that address basic needs and enhance community quality of life. With over $4.2M in funding since its inception in 2015, the foundation prioritizes projects with lasting impact, collaboration, and alignment with its mission. It aims to assist those facing financial challenges while promoting financial literacy and community enhancement initiatives.

The Bank of America Charitable Foundation focuses on supporting organizations that empower communities through basic needs, income creation, and stable housing. By investing in health and job opportunities, they aim to enhance economic mobility for low- and moderate-income families. Their partnerships target vulnerable populations, ensuring equitable access to resources that foster community vitality and resilience. This initiative emphasizes the importance of stable housing as a foundation for personal and communal growth.

The American Electric Power Foundation provides grants to 501(c)(3) organizations focused on educational improvement, particularly in STEM fields, and basic human services such as hunger and housing. Organizations must operate within AEP's service territory or have a broader beneficial purpose. The Foundation also supports social justice initiatives and environmental protection efforts. Eligible applicants must affirm compliance with anti-discrimination policies and demonstrate commitment to diversity and inclusion.

The JFNY Grant for Arts & Cultural Exchange supports U.S. non-profit organizations aiming to enhance understanding of Japanese arts and culture. Eligible projects include performances, workshops, and exhibitions, with priority given to those with additional funding and in areas with limited access to cultural events. Applications must be submitted at least one month prior for online projects and three months for others. The grant covers expenses like travel, publicity, and artist fees, and is reimbursed upon project completion.

The George F. Moss Foundation Grant supports charitable organizations in the greater Milwaukee area. Established in memory of George French Moss, who dedicated his life to business and philanthropy, the foundation emphasizes local impact. It seeks to fund initiatives that enhance community welfare, reflecting Mr. Moss's lifelong commitment to charitable endeavors. This grant is ideal for organizations aiming to make a significant difference in the lives of Milwaukee residents, ensuring his legacy continues through meaningful contributions.

Asthma-Safe Homes Program Environmental Services Training Provider

This Request for Applications (RFA) is for a partner who can provide training and technical assistance on environmental home assessment, repair, and remediation of asthma trigger sources to organizations delivering the Wisconsin Department of Health Services’ Asthma-Safe Homes Program environmental services. The total available funds is up to $15,000.

Funding opportunity description

The purpose of this request for applications is to seek a partner who can provide training and technical assistance on environmental home assessment, repair, and remediation of asthma trigger sources to organizations delivering the Wisconsin Department of Health Services’ (WI-DHS) Asthma-Safe Homes Program environmental services. This program is a Children’s Health Insurance Program (CHIP) Health Services Initiative (HSI) funded through the Centers for Medicare and Medicaid (CMS). The grant is expected to begin on October 1, 2026.

The Steve Brovold Scholarship, offered by the St. Croix Valley Foundation, supports male students pursuing an Elementary Education degree at the University of Wisconsin-River Falls. With a mission to enhance local communities through educational opportunities, this scholarship aims to foster the next generation of educators who will have a meaningful impact in their communities. The foundation, established in 1995, has a rich history of connecting generosity with impactful initiatives across the St. Croix Valley.

The U.S. Department of Transportation's Office of Small and Disadvantaged Business Utilization is offering funding through the Small Business Transportation Technical Assistance Center (SBTTAC) program. This initiative aims to assist small businesses in Region 3 by providing essential technical support and business development resources. The cooperative agreement includes a base year of 10 months with two additional option years, fostering growth while ensuring regulatory compliance and reducing barriers for small businesses.

The Great Apes and Gibbons Program Grant, administered by the Arcus Foundation, supports conservation efforts for great apes and gibbons across 24 priority landscapes in Africa and Asia. The program emphasizes sustainable coexistence between humans and wildlife, having awarded over 2,000 grants to more than 500 organizations globally. Funding is not available for individuals or specific lobbying activities, ensuring resources are directed towards impactful conservation initiatives.

The Chi-Cal Rivers Fund Grant, administered by the National Fish and Wildlife Foundation, aims to enhance the waterways of the Chicago and Calumet region. This initiative focuses on reducing stormwater runoff through nature-based infrastructure, improving fish and wildlife habitats, and promoting community engagement. The program supports projects under three main categories: habitat quality improvement, stormwater solution expansion, and activation of restored natural areas, encouraging strategic investments for ecological resilience.

About PCORI

PCORI funds patient-centered comparative clinical effectiveness research (CER).

Our Mission

PCORI helps people make informed healthcare decisions, and improves healthcare delivery and outcomes, by producing and promoting high-integrity, evidence-based information that comes from research guided by patients, caregivers, and the broader healthcare community.

Broad Pragmatic Studies PCORI Funding

The Patient-Centered Outcomes Research Institute (PCORI) intends to issue a Broad Pragmatic Studies (BPS) PCORI Funding Announcement (PFA), seeking to fund patient-centered comparative clinical effectiveness research (CER) projects. 

Research Initiative Highlights

CER compares at least two available health treatments, services or care delivery strategies. PCORI seeks proposals that compare clinical interventions (e.g., pharmacological and nonpharmacological treatments, screening and diagnostic approaches) and healthcare delivery system interventions (e.g., workforce, technologies, healthcare service delivery designs) to evaluate potential benefits and harms of different treatment and care delivery options, thus generating evidence that empowers patients, caregivers and the broader healthcare community with information to make informed choices that reflect their needs and preferences.

Special Areas of Emphasis

For Cycle 2 2026, PCORI is particularly interested in submissions that address the following Special Areas of Emphasis (SAE) within the BPS funding opportunity. The purpose of identifying these SAEs is to encourage submissions to these areas, rather than limiting submissions to these topics. Applicants addressing one of the below SAEs should identify the area that is best associated with their research approach:  

• Addressing Obesity
• Diabetes Prevention, Care and Treatment
• Management of Urogynecological and Pelvic Pain
• Pain Management for Individuals Living With Sickle Cell Disease

In PCORI-funded research, patients and other research partners are expected to meaningfully contribute their lived experience or professional expertise to ensure studies are patient-centered, relevant and useful for healthcare decision making. Applicants must address PCORI’s Foundational Expectations for Partnerships in Research — an evidence-based framework supported by tools and resources to guide effective engagement strategies. Applicants are also strongly encouraged to consider the inclusion of a broad range of patient-centered burdens and economic outcomes. 

Broad Pragmatic Studies PFA: Category 1, Category 2 and Category 3 Study Specifications

PCORI will commit up to $120 million in direct costs through this funding opportunity. This funding opportunity contains three categories for funding:

• Category 1: Category 1 will support research projects with direct costs up to and including $5 million.

• Category 2: Category 2 will support research projects with direct costs greater than $5 million and up to a maximum of $12 million. Applications for funding under Category 2 will be required to provide additional information in the Letter of Intent (LOI) and application to justify the size and scope of the proposed research projects and to explain how additional funds are necessary with respect to the scale, scope and complexity of personnel and material resources needed to address the research question.

• Category 3: Category 3 will support research projects with direct costs up to $12 million that utilize PCORnet® to conduct observational studies and/or pragmatic trials that are national in scale. Category 3 PCORnet Studies® must include two or more Clinical Research Networks and share study progress, performance metrics and best practices with the network to promote continuous learning and improvement. PCORnet Studies® will leverage the PCORnet Common Data Model® as appropriate. Additional details about Category 3 can be found on the PCORI website.  

Enterprise Community Partners

Enterprise Community Partners (Enterprise) is a national nonprofit that exists to make a good home possible for the millions of families without one. We support community development organizations on the ground, aggregate and invest capital for impact, advance housing policy at every level of government, and build and manage communities ourselves. Since 1982, we have invested $80.9 billion and created 1 million homes across all 50 states, the District of Columbia, Puerto Rico and the U.S. Virgin Islands – all to make home and community places of pride, power and belonging.

Midwest Asset Management University Program

Operating, maintaining, and preserving affordable housing is complex and requires a specialized set of skills and a deep organizational commitment to asset management. Today, affordable housing providers face a variety of economic, operational, and compliance challenges, including rising operating costs, rental arrears, staffing shortages, and an aging portfolio.

Enterprise is launching its first Asset Management University (AMU) Program in the Midwest (Illinois, Indiana, Wisconsin, Missouri, and/or Minnesota) in March 2026 to support mission-aligned, affordable housing providers in meeting these challenges in their efforts to provide housing stability to residents and preserve the long-term affordability of properties.

The Midwest AMU is a comprehensive, five-month training program that seeks to strengthen the asset and property management capabilities of participating housing providers, improving organizations’ capacity to oversee the financial, physical, and operational health of their housing portfolios.

Midwest Asset Management University Cohort 

Enterprise is excited to offer this application for participation in the Asset Management University (AMU) Cohort (the “Cohort”). Up to fifteen (15) eligible organizations will be selected for this Cohort and will receive access to online training offered by the Consortium of Housing and Asset Management (CHAM), peer learning opportunities, and post-training technical assistance.

The Patient-Centered Outcomes Research Institute (PCORI) intends to issue a Broad Pragmatic Studies (BPS) PCORI Funding Announcement (PFA) on Aug. 4, 2026, seeking to fund high-impact, patient-centered comparative clinical effectiveness research (CER) projects. This preannouncement provides potential applicants additional time to identify collaborators; obtain patient and stakeholder input on potential studies; and develop responsive, high-quality applications. 

Patient-centered CER compares at least two available health treatments, services or care delivery strategies. PCORI seeks proposals that compare clinical interventions (e.g., pharmacological and nonpharmacological treatments, screening and diagnostic approaches) and healthcare delivery system interventions (e.g., workforce, technologies, healthcare service delivery designs) to evaluate potential benefits and harms of different treatment and care delivery options, thus generating evidence that empowers patients, caregivers and the broader healthcare community with information to make informed choices that reflect their needs and preferences. 

The Kyle R. Long Scholarship, managed by the Community Foundation of North Central Wisconsin, aims to support graduating seniors from the Medford area who have special educational needs or learning disabilities. Scholarships encourage these students to pursue post-secondary education in any field. In total, over $300,000 will be awarded to more than 200 students across north central Wisconsin, reflecting a commitment to enhancing community life through educational opportunities.

Investing in Dental Care Technology: Grants to Improve Rural Dental Efficiency and Access

Funding opportunity summary

The Wisconsin Department of Health Services (DHS) is seeking applications for competitive grants to support dental clinics in adopting technologies that improve efficiency and increase access to care in rural and semi-rural communities. Dental practices, particularly in more rural areas of the state, face challenges that result in reduced access to care. These challenges include high rates of uninsured patients, low and unpredictable patient volumes, dental workforce shortages, and limited capital resources to adopt innovative technologies. This funding opportunity seeks to address these challenges through increased access to dental technological innovations, which improve dental services in rural Wisconsin by increasing the speed of appointments while maintaining quality of care. This funding will allow dental practices to purchase technologies to deliver high-quality and efficient services. Applicants may apply to multiple Rural Health Transformation Program (RHTP) funding opportunities for which their organizations are eligible.

The National Forest Foundation's Matching Awards Program connects communities to forests by funding stewardship activities that promote engagement with National Forests and nearby public lands. This program aims to create lasting impacts, ensuring that all communities can benefit from the rich resources of these natural areas. By supporting various projects, the program fosters a deeper relationship between people and the environment, ultimately enhancing conservation efforts and community well-being.

Asia-Pacific Network for Global Change Research

The Asia-Pacific region, home to over half the world's population, faces challenges due to its development goals, which strain natural resources, communities, and cultural heritage. These issues are exacerbated by adverse environmental changes. While research has shed light on these problems, it's clear that more challenges lie ahead. The Asia-Pacific Network for Global Change Research (APN) is well-positioned to generate new knowledge and solutions for these evolving global change and sustainability issues by supporting collaborative research and scientific capacity development activities, particularly those aimed at training the next generation of early career professionals.

APN 2025 Call for Proposals: CAPaBLE Programmes

CAPaBLE, our scientific capacity development programme, aims to enhance the capacity of scientists, policymakers and practitioners to assess global change issues, and explore options to resolve issues towards achieving sustainability. Through CAPaBLE, we support activities that enhance capacity at individual, organizational and systemic levels.

Activities of interest under the CAPaBLE Programme

APN supports CAPaBLE activities that enhance existing capacities of developing countries at three levels of individual-based capacity development; group, organisation, network-based capacity development; and societies, governance, and system level capacity development. APN accepts CAPaBLE proposals that engage 1 or more member/approved countries. Proposals must address one or more of the following activities:

SCIENTIFIC CAPACITY DEVELOPMENT ACTIVITIES that promote the following approaches related to one or more of the six thematic areas of APN:

• Utilising and strengthening existing capacity, 
• Creating opportunities to use/instil capacity, 
• Developing new capacity through innovative approaches.

AWARENESS-RAISING AND DISSEMINATION activities through policy- and decision-making communities, civil society, and/or the general public.

SCIENCE-POLICY interfacing in the context of the priority topics.

CAPACITY DEVELOPMENT PARTNERSHIP ACTIVITIES that contribute to the capacity development components of the evolving global change arena, including the UNFCCC Paris Agreement, IPCC, IPBES, post-2015 Sustainable Development Goals, Sendai Framework for Disaster Risk Reduction, and the UN Decade of Ocean Science, and ongoing and new global change and sustainability research programmes.

Activities geared towards using SCIENCE COMMUNICATION to disseminate knowledge generated from projects, particularly to non-science audiences.

The Ethnic Minorities and Women’s Internship Grant supports entry-level athletics administrative positions for one academic year, promoting diversity in NCAA Division II. It provides $30,000 for intern salaries and $3,000 for professional development, benefiting six schools annually from a total budget of $180,000. Eligible applicants must be active NCAA members, with a focus on enhancing ethnic minority and gender representation in athletics administration. This initiative encourages professional growth and compliance in diverse environments.

The Joyce Foundation's Education & Economic Mobility Grants aim to close income and race disparities in college and career success. The foundation prioritizes equitable access to high-quality education, supporting policies for effective educators, high school graduation, and affordable college credentials. Focused on racial equity and economic mobility, it addresses the needs of historically underserved young people in the Great Lakes region and invests in research, policy development, and advocacy to help them recover from the COVID-19 pandemic.