Best Large Grants for Nonprofit Organizations in Wisconsin

The National Institutes of Health (NIH) is seeking to enhance the Strategies to Innovate EmeRgENcy Care Clinical Trials Network (SIREN) through the establishment of a Clinical Coordinating Center (CCC) and Data Coordinating Center (DCC). This initiative aims to improve emergency care outcomes by supporting trials that focus on effective treatments for non-stroke neurological and cardiovascular emergencies. Although applications are not currently being solicited, this notice allows potential applicants to prepare collaborative proposals.

Scholarships

Since awarding our first $500 scholarship in 1987, the Saginaw Community Foundation has awarded college scholarships to area students totaling more than $13.7 million, thanks to our generous donors. Each year, over 500 college-bound or career and technical education students benefit from our scholarship awards.

Our single application process makes it easy to potentially qualify for one or more of our 260+ scholarships.

JustJane Art Scholarship Fund for Women

Truly unique humans like Jane Marie Ewing do not populate the universe very often, and the JustJane Art Scholarship for Women was created to honor her remarkable spirit.

Jane was an artist at heart, finding joy in countless creative pursuits – whether baking delectable treats, capturing life’s beauty through photography, or expressing her imagination in fashion and digital illustration. Her zest for life was infectious, often bringing laughter through her playful “Jane Pranks”, which will forever live in the hearts of family and friends. Jane shared an inseparable bond with Kyle, each the center of the other’s universe. Tragically, Jane was taken from this world unexpectedly in 2025.

Her vibrant artistic soul touched every aspect of her life – from painting and interior design to crafting costumes for parties and pranks. Though her passion for art wasn’t fully nurtured early on, once she embraced it later in life, creativity flowed freely, illuminating the lives of everyone around her. Jane saw beauty everywhere, and her art became a reflection of that vision.

This scholarship carries forward Jane’s legacy, helping future generations cultivate their own artistic passions. It is a reminder to future generations that art has the power to transform lives.

The Transformative Organizing Grants, funded by the Arch Community Fund, aim to bolster grassroots movements advocating for systemic change. These grants, ranging from $15,000 to $25,000, prioritize organizations with 501(c)(3) status and an annual budget under $1 million. The focus is on empowering community leadership through anti-capitalist solutions, promoting intersectionality, and addressing immediate needs while fostering long-term structural change. Eligible groups are encouraged to apply for support in their transformative organizing efforts.

The Schlecht Family Foundation offers Capacity Building Grants aimed at enhancing organizational effectiveness and efficiency for nonprofits in Dane County and rural Wisconsin. These grants support innovative solutions to community challenges, focusing on meaningful work, character development for youth, and fostering connections to nature. Eligible organizations must be 501-C3 registered or have a fiscal sponsor and must not engage in lobbying or political activities. Grants are tailored to meet specific needs, promoting sustainable impact.

The Schlecht Family Foundation Inc is committed to transforming communities in Dane County and rural Wisconsin through innovative support for organizations. Their grantmaking focuses on capacity building, seed funding, general operating grants, and impact investments, aiming to empower individuals through meaningful work, foster connections to nature, and help youth develop essential life skills. The foundation prioritizes organizations that align with their mission and avoid funding capital campaigns or endowments.

The Grassroots Organizing National Grant Program, funded by the Ben & Jerry's Foundation, supports small, community-led organizations in the U.S. working to confront social and environmental injustices. Grants of up to $30,000 per year are available for two years, prioritizing organizations with budgets under $350,000. The program emphasizes grassroots organizing and community empowerment, inspired by the legacy of John Lewis. Eligible applicants must focus on collective action and local leadership to drive social change.

The Spight Family Foundation Grants aim to enhance the well-being of families and support environmental initiatives that benefit future generations. They welcome charitable organizations that align with their mission, regardless of location, with a primary focus on Northern California. By funding various projects, the foundation seeks to foster community health and sustainability, making a lasting impact on both local and global scales.

The SUS Resident Research Scholar Award offers $30,000 for one year to surgical residents engaged in basic or translational research. Eligible candidates must have completed two years of training and commit to full-time research with an SUS member. Notably, applicants must avoid mentors on the exclusion list, ensuring a fair and competitive application process. This funding promotes innovative surgical research and supports the development of future leaders in the field.

The Sandusky-Firelands Alzheimer’s Scholarship provides financial support to residents of Erie County, Ohio, pursuing degrees in the Medical and Health Care fields, particularly those interested in working with geriatric patients. Established in 1995 by a dedicated non-profit organization, this scholarship aims to enhance community well-being and quality of life. Renewals for up to three additional years are possible, depending on financial need and the discretion of the Scholarship Advisory Committee.

About Us

For over three decades, the Hamilton Education Foundation (HEF) has been sparking innovation and expanding horizons within our classrooms. Since 1991, this community-powered non-profit has channeled more than $2.5 million from passionate individuals, local businesses, and forward-thinking organizations directly into the hands of Hamilton’s students and teachers. 

By funding transformative workshops, creative projects, and classroom grants, HEF doesn't just support education—it inspires students to dream bigger, rewards academic excellence, and builds a stronger, more vibrant community.

Our Vision

The vision of the Hamilton Education Foundation is to assist in achieving creative and academic excellence for the 21st Century through funding activities and projects for students and educators in the Hamilton School District.

Our Mission

Our mission, in partnership with the community, is to fund, Enhanced, Extended, and Enriched learning opportunities for students and educators in the Hamilton School District.

Teacher Grants

Classroom Impact Grant

The Classroom Impact Grant funds educator-led projects that directly improve student learning. We provide the financial support teachers need to bring fresh ideas, modern resources, and creative learning experiences into their classrooms.

The Clarence and Bonnie Shaffer Scholarship, administered by the Marshall County Community Foundation, aims to support students affiliated with Trinity United Methodist Church pursuing post-secondary education in ministry, music ministry, or education. Preference is given to first-year undergraduates, but graduate students may also qualify if no undergraduates apply. This scholarship represents a commitment to nurturing local talent and fostering educational opportunities within the community.

The CRSJ Racial Justice in Education Grant, administered by the National Education Association, aims to enhance racial equity within education by funding initiatives that promote awareness, leadership development, and solidarity among diverse racial groups. Grants typically range from $10,000 to $75,000, supporting projects that address racism and foster equitable policies in educational settings, thereby accelerating efforts towards social justice.

Beekhuis Scholarship

Award:

• One time award of $4,000.

The OJJDP FY 2026 Internet Crimes Against Children On-Line Child Protection System (ICACCOPS) funding opportunity aims to enhance and maintain critical investigative tools for child exploitation cases. ICACCOPS provides a robust IT infrastructure to support data services, network security, and management tools for law enforcement. This initiative strengthens the efforts of the national network of ICAC Task Forces, which are dedicated to combating technology-facilitated child sexual exploitation across the United States.

About

Central Carolina Community Foundation is a nonprofit organization that helps generous people give back to the Midlands of South Carolina in ways that matter. Since 1984, we’ve been a trusted partner, helping individuals, families, and businesses make smart, meaningful contributions that support local nonprofits, scholarships, and community projects.

Easterby Family Scholarship ($7,000)

This renewable scholarship is for students from Laurens County, South Carolina who are pursuing graduate or post-graduate education in the fields of theology or medicine. 

The U.S. Department of Energy (DOE) is launching the PROSPECT Program to enhance education in critical technologies, targeting an investment of up to $100 million. This initiative aims to develop a skilled workforce across the critical minerals and materials sector, supporting the entire value chain from resource extraction to recycling. By fostering collaboration among academia, industry, and national laboratories, the program seeks to strengthen U.S. economic competitiveness and energy security.

The Community Foundation of the Rappahannock River Region

The Community Foundation is a devoted advocate for the vitality and well-being of the Rappahannock River Region. We are a 501(c)(3) nonprofit that manages and distributes charitable giving in the counties of Stafford, Spotsylvania, King George, and Caroline, and the City of Fredericksburg.

Scholarships

One of The Community Foundation’s strategies for preserving and growing the quality of life in our region is supporting higher education for area students. Generous individuals and families, companies and organizations establish endowed scholarship funds and the proceeds from these funds benefit deserving students. Donors work with foundation staff to determine appropriate criteria for each fund. The Community Foundation currently administers more than fifty scholarship funds.

The Mary E. Berger Scholarship Fund

The Mary E. Berger Scholarship was established with a gift from Mary E. Berger and a future gift by the estate of Mary E. Berger to assist high school students who wish to attend college or university or professional school to pursue studies in art, music, history, political science, English, journalism and related liberal arts subject.

Who We Are

OneStar strengthens Texas communities by creating pathways for individuals and organizations to engage, connect, and accelerate their impact.

OneStar AmeriCorps VISTA Project

OneStar AmeriCorps VISTA Project places skilled individuals with a diverse range of backgrounds at nonprofits and agencies throughout the state of Texas. AmeriCorps VISTA members serve full-time for one year on capacity-building projects to advance your organization’s anti-poverty mission.

OneStar AmeriCorps VISTA Project places community-driven individuals with nonprofits & agencies throughout Texas on transformative projects focused specifically on building organizational capacity and infrastructure to alleviate poverty. Get the support you need to accelerate your efforts in volunteer management, marketing, community outreach, fundraising, program development, and more!

Capacity building activities include:

• Volunteer Engagement
• Fundraising & Development
• Communication & Marketing
• Community Engagement & Outreach
• Program Development

The Karim Thomas Ziyad Memorial Engineering Scholarship Fund supports students from Washington County or nearby areas pursuing a career in engineering, especially in Mechanical Engineering. Established in memory of Karim Thomas Ziyad, this scholarship aims to empower deserving students to achieve their educational goals. The fund is part of the Community Foundation of Washington County Maryland, which offers numerous scholarships to enhance educational opportunities for local students.

The Historical Transportation Marker Program provides grants to commemorate significant transportation methods used before 1945, such as canals, bridges, railroads, and aircraft. Eligible applicants include 501(c)(3) organizations and government entities in the U.S. Grants aim to recognize historical facts with clear inscriptions, supported by documentation, while ensuring markers are publicly accessible near existing sites. This initiative highlights the evolution of transportation and its impact on community development.

The Ed & Mildred Schroeder Scholarship, offered by the Coastal Bend Community Foundation, aims to enhance the quality of life in the Coastal Bend through educational support. This scholarship is available to graduating seniors or current college students pursuing a degree in education, demonstrating financial need, and enrolled in at least 12 credit hours. By providing effective grants and scholarships, the foundation fosters community philanthropy and addresses local educational needs.

The Rodgers Family Civil Engineering Scholarship, managed by the Northern Piedmont Community Foundation, supports graduating seniors from Fauquier County pursuing civil engineering degrees. Candidates must demonstrate financial need, initiative, motivation, and leadership qualities. With a history of over $39 million in community support since 2000, this scholarship exemplifies the Foundation's commitment to fostering educational opportunities. Award amounts may vary and are renewable, making it a valuable resource for aspiring engineers in the region.

The Health Sciences Scholarship, established in 2000 by Emeritus Professor James Hauxhurst, supports students from the Fox Valley area pursuing health science majors at UW institutions. Awarding $3,000 in total, it is divided into two payments of $1,500 for the fall and spring semesters. Eligible applicants include graduating high school seniors and continuing college students, with financial need being a consideration. This scholarship aims to foster future leaders in health care for the community.

About AGC of California

Since 1920, we have worked together with our members to provide advocacy, education, career development, and networking opportunities to experienced and next generation construction and contracting professionals. From the moment you become an AGC member, we go to bat for you with state and local governments, while helping you connect with industry leaders through services, innovative programs, and events.

The AGC Construction Education Foundation (AGC CEF) provides resources, support, and training through innovative programs in order to attract, develop, and retain a strong, motivated, and skilled workforce. We believe construction careers transform lives. We connect people and communities to meaningful work and rewarding futures. We inspire the industry to be a place where people belong, grow and build lasting legacies.

AGC CEF Skilled Trades Scholarship

This scholarship is designed to support students pursuing post-secondary construction industry training programs. Scholarship amounts range from $500 to $2,500.

The John M. O'Quinn Foundation Grant, established in 1986, has contributed over $192 million to various charitable activities, focusing primarily on Houston and its surrounding areas. The Foundation supports tax-exempt organizations and governmental units, emphasizing conservation, education, healthcare, and programs for underprivileged youth. Grants are not available for type III supporting organizations, individuals, or foreign charities, ensuring a targeted impact within the local community.

The Northeast Sea Grant Consortium and NOAA’s Northeast Fisheries Science Center invite proposals to explore the interactions between fishing communities and offshore wind development in the U.S. Northeast. This initiative aims to enhance understanding of community resilience and economies, while fostering collaborative research that informs decision-making. Proposals should utilize qualitative and quantitative methods and involve at least one Co-PI from the six states of the NESGC, with a requirement for a 25% non-federal match.

The Actions of Public Witness Grant, offered by the Unitarian Universalist Funding Program, provides matching grants of up to $1,500 to Unitarian Universalist congregations engaging in timely actions of public witness. This initiative supports efforts in social and environmental justice, encouraging congregations to mobilize during critical moments. Grants are available on a rolling basis and are intended for urgent projects that extend beyond the regular grant timeframe. Notably, individual applications are not accepted.