Best Yankton County Grants for Nonprofits in South Dakota

2026 ASPCA Grants for Shelters and Spay/Neuter Clinics

The American Society for the Prevention of Cruelty to Animals® (ASPCA®) is offering up to $14 million in grants to support shelters and spay/neuter clinics in meeting the needs of vulnerable animals throughout the United States, including addressing the shortfall in available spay/neuter surgeries. We will fund qualified proposals that support:

• Critical shelter infrastructure
• Strengthening shelter essentials
• Increasing the number of spay/neuter surgeries year-over-year 
• Major capital projects that increase spay/neuter capacity
• Special projects that increase spay/neuter capacity

Shelter Grants

Critical Shelter Infrastructure

Only one application per agency/organization will be considered. 

Applicants may choose only one of the five funding categories. Our interest is in meeting your most pressing needs in one of the offered categories; we do not have our own preference for funding one category over another. We will fund the most compelling proposals, regardless of category chosen.

2026 ASPCA Grants for Shelters and Spay/Neuter Clinics

The American Society for the Prevention of Cruelty to Animals® (ASPCA®) is offering up to $14 million in grants to support shelters and spay/neuter clinics in meeting the needs of vulnerable animals throughout the United States, including addressing the shortfall in available spay/neuter surgeries. We will fund qualified proposals that support:

• Critical shelter infrastructure
• Strengthening shelter essentials
• Increasing the number of spay/neuter surgeries year-over-year 
• Major capital projects that increase spay/neuter capacity
• Special projects that increase spay/neuter capacity

Shelter Grants

Strengthening Shelter Essentials

Only one application per agency/organization will be considered. 

Applicants may choose only one of the five funding categories. Our interest is in meeting your most pressing needs in one of the offered categories; we do not have our own preference for funding one category over another. We will fund the most compelling proposals, regardless of category chosen.

2026 ASPCA Grants for Shelters and Spay/Neuter Clinics

The American Society for the Prevention of Cruelty to Animals® (ASPCA®) is offering up to $14 million in grants to support shelters and spay/neuter clinics in meeting the needs of vulnerable animals throughout the United States, including addressing the shortfall in available spay/neuter surgeries. We will fund qualified proposals that support:

• Critical shelter infrastructure
• Strengthening shelter essentials
• Increasing the number of spay/neuter surgeries year-over-year 
• Major capital projects that increase spay/neuter capacity
• Special projects that increase spay/neuter capacity

Spay/Neuter Grants

Increasing Spay/Neuter Surgeries

Only one application per agency/organization will be considered. 

Applicants may choose only one of the five funding categories. Our interest is in meeting your most pressing needs in one of the offered categories; we do not have our own preference for funding one category over another. We will fund the most compelling proposals, regardless of category chosen.

2026 ASPCA Grants for Shelters and Spay/Neuter Clinics

The American Society for the Prevention of Cruelty to Animals® (ASPCA®) is offering up to $14 million in grants to support shelters and spay/neuter clinics in meeting the needs of vulnerable animals throughout the United States, including addressing the shortfall in available spay/neuter surgeries. We will fund qualified proposals that support:

• Critical shelter infrastructure
• Strengthening shelter essentials
• Increasing the number of spay/neuter surgeries year-over-year 
• Major capital projects that increase spay/neuter capacity
• Special projects that increase spay/neuter capacity

Spay/Neuter Grants

Spay/Neuter Major Capital Projects

Only one application per agency/organization will be considered. 

Applicants may choose only one of the five funding categories. Our interest is in meeting your most pressing needs in one of the offered categories; we do not have our own preference for funding one category over another. We will fund the most compelling proposals, regardless of category chosen.

The ASPCA is offering up to $14 million in Spay/Neuter Grants for shelters and clinics across the U.S. to enhance spay/neuter services for vulnerable animals. Proposals can address critical infrastructure needs and major capital projects to increase spay/neuter capacity. Only one application per organization is permitted, and applicants must choose one funding category. The focus is on compelling proposals that meet the most urgent needs.

The Amy Adina Schulman Memorial Fund

The Amy Adina Schulman Memorial Fund is a Princeton, New Jersey-based endowment fund providing grants to individuals, young adults who volunteer or intern for progressive social action projects or programs in an area of their interest and commitment. The Amy Adina Fund also sponsors a lecture each year on a relevant and timely topic related to its educational mission.

The Amy Adina Schulman Memorial Fund was started in 1987 one year after Amy Adina, 20, died suddenly while a student and activist at Rutgers University. It is a realization of her family and her communities’ desire to celebrate her life, to fulfill her dreams and her potential. Since its inception, almost 1,500 grants have been awarded for work in Africa, Asia, Latin America, the Middle East, and the United States—nearly $1,000,000 in total. The Amy Adina Schulman Memorial Fund is a 501(c)3 nonprofit organization.

About Our Grants

Small grants (depending on length of service), are awarded to as many applicants as possible rather than giving larger amounts to fewer individuals. The number of awards has grown each year thanks to annual contributions as well as to gifts sent to the Fund to honor special occasions and life cycle events.

The BJS FY 2026 National Incident-Based Reporting System Estimation Program aims to enhance statistical protocols for crime and arrest data collection in the U.S. This funding opportunity supports the ongoing development of the NIBRS Estimation System, focusing on improving data quality, timeliness, and estimation methodologies. By refining these processes, the program seeks to address public safety challenges and provide reliable national estimates, thereby ensuring effective law enforcement and crime prevention efforts.

The BJS FY 2026 Annual Surveys of Probation and Parole (ASPP) from 2026 to 2030 will provide crucial insights into individuals under community supervision in the U.S. By collecting comprehensive data on probation and parole populations, this initiative aims to report accurately on the dynamics and characteristics of correctional supervision. The data collection process will address various challenges, ensuring that the information reflects the realities of both large and small supervising agencies across the country.

The Women's Initiative for Screening and Health (WISH) aims to enhance women's health by increasing access to preventive services. This initiative brings together healthcare providers, academic institutions, and patient-centered organizations to improve the adoption of evidence-based guidelines for women's preventive health. By raising awareness and ensuring the guidelines are integrated into clinical practice, WISH addresses key health challenges faced by women throughout their lives.

The Food and Agricultural Sciences National Needs Graduate and Postgraduate Fellowships program, managed by the USDA's NIFA, aims to enhance the training of new graduate students in food and agricultural sciences. It provides essential funding for master's, DVM, and doctoral students, focusing on developing the next generation of experts to address critical needs in agricultural sciences. This initiative supports U.S. citizens and residents in achieving their educational goals and contributing to the USDA's mission.

The BJS FY 2026 Criminal History Record Assessment and Research Program (CHRARP) aims to enhance the Bureau of Justice Statistics' ability to analyze recidivism and criminal history data. This program will support the standardization of criminal records across jurisdictions, enabling accurate statistical analyses. By refining existing data coding systems and addressing data quality issues, the CHRARP will improve research on offenders' patterns and careers, ultimately contributing to effective criminal justice policies.

The OVW Fiscal Year 2026 Training and Services to End Violence and Abuse Against Individuals with Disabilities and Deaf People Program aims to empower states, local and Tribal governments, and nonprofit organizations to provide crucial training and resources. This initiative focuses on addressing domestic violence, stalking, sexual assault, and caregiver abuse against individuals with disabilities and Deaf individuals, enhancing direct services and support for these vulnerable populations.

The BJA FY 2026 Smart Reentry Demonstration Program aims to support state, local, and tribal governments in implementing effective reentry strategies for individuals transitioning from correctional facilities back to their communities. This program encourages comprehensive interventions designed to reduce recidivism by addressing various reentry needs, as outlined in the Second Chance Act. Applications are due by October 1, 2026, at 8:59 PM ET, and are submitted through JustGrants.

The BJA FY 2026 Harold Rogers Prescription Drug Monitoring Program aims to enhance the capabilities of agencies in collecting and analyzing prescription data for controlled substances. By establishing a centralized database, this initiative will aid in the prevention of drug diversion and abuse, particularly of opioids. The program emphasizes the integration of data with health information exchanges and electronic health records, fostering local decision-making while addressing the needs of tribal and rural areas to combat substance abuse effectively.

The BJA FY26 Body-Worn Camera Policy and Implementation Program aims to assist law enforcement agencies in acquiring body-worn cameras and establishing comprehensive BWC programs. This initiative addresses the increasing demand for reliable video evidence in criminal cases, enhancing documentation and prosecutorial outcomes. By utilizing BWCs, agencies can deter assaults on officers and protect them against false accusations, ultimately improving community trust and accountability in law enforcement practices.

The BJA FY 2026 Investigating and Prosecuting Sexual Assaults in Confinement Facilities Program aims to enhance state, local, and tribal capacities to investigate and prosecute sexual assault incidents within confinement facilities. This funding opportunity is designed for law enforcement and prosecutorial agencies to effectively address and reduce sexual assault occurrences while improving prosecution success rates. Applications are due by September 30, 2026, at 8:59 PM ET.

The BJA FY 2026 Intellectual Property Enforcement Program aims to bolster public health, safety, and the economy by combating counterfeit goods and product piracy. This funding opportunity supports the formation or enhancement of law enforcement intellectual property enforcement task forces. It assists various jurisdictions in tackling intellectual property theft and related crimes, while also aiding in the investigation and prosecution of such offenses, thereby addressing the associated violent crime.

The National Institutes of Health (NIH) is seeking to enhance the Strategies to Innovate EmeRgENcy Care Clinical Trials Network (SIREN) through the establishment of a Clinical Coordinating Center (CCC) and Data Coordinating Center (DCC). This initiative aims to improve emergency care outcomes by supporting trials that focus on effective treatments for non-stroke neurological and cardiovascular emergencies. Although applications are not currently being solicited, this notice allows potential applicants to prepare collaborative proposals.

The National Institute on Aging (NIA) is inviting applications for the Alzheimer's Drug-Development Program (U01 Clinical Trial Optional). This initiative seeks to support pre-clinical and early-stage clinical development of innovative drug candidates aimed at preventing Alzheimer's disease or treating its symptoms. The program encourages collaboration among researchers and aims to enhance the therapeutic pipeline for AD through targeted approaches. This notice allows potential applicants time to prepare robust projects.

The National Institutes of Health (NIH) is dedicated to advancing emergency care through the Strategies to Innovate Emergency Care Clinical Trials Network (SIREN). This initiative seeks to establish clinical enrollment hubs that will enhance the network's ability to conduct trials aimed at improving outcomes for patients experiencing neurological and cardiovascular emergencies. Although applications are not currently being accepted, this notice encourages potential applicants to prepare collaborative and impactful proposals.

The Established Clinician Investigator Award to Support Mentoring (KS1) is designed to provide established clinician investigators with dedicated time for mentoring early-career clinician research scientists. This initiative by the US Dept. of Health & Human Services: National Institutes of Health (NIH) aims to enhance the quality of mentorship, fostering the development of future leaders in clinical research. It supports a sustained commitment to training and guidance, ensuring a robust pipeline of skilled professionals.

The Mentored Career Transition Award (KT1/R00) offers a biphasic funding opportunity for up to 5 years, supporting the transition of postdoctoral researchers to independent faculty positions. The first phase provides 1-2 years of mentored career development, while the second phase grants up to 3 years of independent research support, contingent upon satisfactory progress and faculty appointment. This grant aims to enhance the capacity of early-career researchers in achieving research-intensive roles.

The Mentored Clinician Research Scientist Career Development Award (KC1) from the NIH supports clinician research scientists for up to five years, providing dedicated time for intensive research career development. This award aims to guide candidates with clinical doctoral degrees towards achieving research independence by pairing them with experienced mentors who can help navigate their career paths.

The Mentored Research Scientist Career Development Award (KR1) offers crucial support for researchers aiming for independence. Funded by the US Dept. of Health & Human Services through the NIH, this award allows candidates to engage in intensive research training under a mentor's guidance for up to five years. It is designed for those with research doctoral degrees, facilitating their transition into independent research roles and enhancing their contributions to the scientific community.

Patient Advocate Foundation

Patient Advocate Foundation is the nation’s most comprehensive nonprofit dedicated to helping patients navigate, access, and afford the care they need—while improving the healthcare system for all.

Patient Advocate Foundation provides financial assistance to help patients afford treatment and cost of living needs, personalized case management to navigate complex healthcare and social needs challenges, and a wide array of resources to empower people to take charge of their health. Since our founding in 1996—and joining forces with the PAN Foundation in 2026—we have helped 3.8 million patients navigate and access care, granted over $7 billion in financial assistance, served 350,000 people through personalized case management and elevated the patient’s voice to drive improvements in the healthcare system.

Mucopolysaccharidosis Type VII (MPS VII) Fund

Help with healthcare costs for mucopolysaccharidosis type VII

This TotalAssist Health Equity Fund helps you pay for out-of-pocket healthcare costs, including medication copays, coinsurance, and deductibles, health insurance premiums, and other expenses.

Approved medications

Patient Advocate Foundation covers all the prescription medications for each diagnosis, including generic or bioequivalent drugs, that meet any of the following criteria: FDA-approved, listed in official compendia, and/or listed in published evidence-based or clinical guidelines. See approved medication list for this condition.

Patient Advocate Foundation verifies your diagnosis and treatment plan with your provider directly. We also automatically verify the income eligibility for every applicant. 

Patient Advocate Foundation

Patient Advocate Foundation is the nation’s most comprehensive nonprofit dedicated to helping patients navigate, access, and afford the care they need—while improving the healthcare system for all.

Patient Advocate Foundation provides financial assistance to help patients afford treatment and cost of living needs, personalized case management to navigate complex healthcare and social needs challenges, and a wide array of resources to empower people to take charge of their health. Since our founding in 1996—and joining forces with the PAN Foundation in 2026—we have helped 3.8 million patients navigate and access care, granted over $7 billion in financial assistance, served 350,000 people through personalized case management and elevated the patient’s voice to drive improvements in the healthcare system.

Mucopolysaccharidosis Type VII (MPS VII) Health Equity Fund

Help with healthcare costs for mucopolysaccharidosis type VII (health equity)

This TotalAssist Health Equity Fund helps you pay for out-of-pocket healthcare costs, including medication copays, coinsurance, and deductibles, health insurance premiums, and other expenses.

Health Equity Funds offer help to eligible patients living in areas identified as having increased social and financial needs, as well as higher rates of chronic conditions. Eligibility is determined in part by home address zip code.

Approved medications

Patient Advocate Foundation covers all the prescription medications for each diagnosis, including generic or bioequivalent drugs, that meet any of the following criteria: FDA-approved, listed in official compendia, and/or listed in published evidence-based or clinical guidelines. See approved medication list for this condition.

Patient Advocate Foundation verifies your diagnosis and treatment plan with your provider directly. We also automatically verify the income eligibility for every applicant. 

The LEGO Foundation Fellowship

Advancing the science and practice of supporting children to thrive

The LEGO Foundation Fellowship is a global initiative supporting researchers working to deepen our understanding of how children thrive. Spanning disciplines from education and psychology to public health, data science, and humanitarian studies, the fellowship brings together early- and mid-career scholars whose work has the potential to generate evidence that matters for children’s lives.

Fellows receive three years of flexible support to pursue rigorous, practically relevant research, and join a cohort of peers working across the fellowship’s themes. In addition to funding research, the program fosters a community of scholars engaged in meaningful exchange with one another and with research, policy, and practice audiences.

The LEGO Foundation Fellowship is developed in partnership with the LEGO Foundation, and administered by SSRC as part of its commitment to supporting scholars whose work bridges research and real-world impact.

Research themes

The LEGO Foundation Fellowship welcomes research proposals that advance understanding of children’s thriving through one of the following three themes: the youngest children in crisis and conflict settings; inclusion and wellbeing of neurodivergent children; and children’s learning and development in an AI-enabled world. Applicants may explore the role of play where it is relevant to the research question. The consideration of play is optional and not a condition of eligibility.