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Large Grants for Nonprofit Organizations in Africa

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Search Through Large Grants for Nonprofit Organizations in Africa

Looking for Large Grants for Nonprofit Organizations in Africa? Find the perfect grant for your nonprofit on Instrumentl

32 grants

$1.3M total

$10K median

32
Available grants

$1.3M
Total funding amount

$10K
Median grant amount

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Last updated: March 2, 2026. Next update: April 5, 2026.

Rolling deadline

Unspecified amount

The AJA Foundation is dedicated to addressing fundamental human rights by providing global support for initiatives focused on clean water, education, and healthcare. Through substantial investments, including over $3 million in clean water projects and $4 million in educational programs, the foundation aims to create equitable opportunities for disadvantaged communities. Their commitment helps improve health outcomes, educational access, and economic mobility, ensuring that access to essential resources is not determined by one's background.

Rolling deadline

Unspecified amount

The Big G Charitable Foundation, founded in 2009 by Mike Galesi, is dedicated to supporting environmental conservation and emergency relief efforts. Inspired by his father, John (Big G), Mike's commitment to helping others drives the foundation's mission to protect the defenseless and promote sustainability. Through grants, the foundation aids qualified non-profit organizations focused on these critical areas, ensuring that both our planet and those in crisis receive the support they need.

Rolling deadline

Unspecified amount

The Brutten Family Foundation Grant focuses on enhancing access to the outdoors, quality education, and mental health services. Established in 1996, the foundation supports organizations that align with its core pillars: environment, education, and mental health. By nurturing local and global initiatives, the foundation aims to inspire the next generation of stewards for a healthier planet. They welcome applications from 501(c)(3) organizations worldwide committed to making a positive impact.

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Rolling deadline

Unspecified amount

The Cosmopolitan of Las Vegas Charitable Donations program emphasizes community engagement through food relief, educational enhancements, and inclusive art initiatives. Focused on supporting low-income individuals, students, and underrepresented groups, the program aims to foster a compassionate environment. By promoting diversity and inclusion, it ensures that assistance is extended without discrimination. Organizations can apply for cash or in-kind support to help further these goals, reflecting the commitment to community welfare and sustainable impact.

Rolling deadline

Unspecified amount

The Creag Foundation, established in 2009 in Woodinville, Washington, provides funding to innovative 501(c)(3) nonprofit organizations addressing social issues. Focused on smaller organizations, the foundation seeks to support those with unique approaches to improve the human condition. Eligible applicants must have held 501(c)(3) status for at least one year and present a new or previously unaddressed solution to societal challenges. Applications are by invitation only, encouraging creativity and passion in charitable work.

Rolling deadline

Up to US $300,000

The Draper Richards Kaplan Foundation provides grants to early-stage social entrepreneurs working on scalable solutions to pressing social and environmental issues. By supporting organizations with innovative approaches and proven impact, they aim to uplift underserved communities globally. The foundation offers operational support, funding of up to $300,000 over three years, and fosters a collaborative community among its portfolio organizations. They focus on candidates demonstrating measurable impact and sustainable growth potential.

Rolling deadline

Unspecified amount

The Global Fund for Children invites community-based organizations worldwide to partner in improving the lives of children and youth. They seek dynamic groups aligned with their mission, focusing on grassroots solutions to tackle poverty, injustice, and discrimination. With a commitment to education, gender justice, safety, climate resilience, and youth empowerment, GFC builds strong relationships with potential partners, ensuring mutual growth and impact without requiring formal proposals.

Rolling deadline

US $10,000 - US $250,000

The MacFarlane Foundation, established in 2009, is dedicated to enhancing the quality of life for individuals and communities through strategic grantmaking. It supports U.S. public charities focused on education, economic empowerment, climate change, health, and women's well-being. Grants range from $10,000 to $250,000, with a commitment to fostering growth in organizations. The foundation invites proposals annually, ensuring impactful contributions to various causes both domestically and internationally.

Rolling deadline

More than US $50,000

The Michael & Susan Dell Foundation provides grants to organizations focused on improving the lives of children in urban poverty in the U.S., India, and South Africa. They prioritize projects in education, health, and family economic stability. Grants typically do not exceed 25% of a project's budget or 10% of an organization's annual expenses. The foundation seeks to partner with organizations already making an impact, ensuring funding supports impactful social enterprises.

Rolling deadline

Unspecified amount

The Moderna Charitable Foundation, established in 2022, aims to enhance public health and healthcare access while fostering scientific education and inclusion in underserved communities. Their initiatives include grant-making to aligned organizations, supporting humanitarian crises, and employee matching for personal causes. The Foundation focuses on building resilient health ecosystems, advancing STEM education, and addressing systemic barriers in communities, all while committed to addressing the ongoing impact of COVID-19.

Rolling deadline

Unspecified amount

The Pentair Foundation, a corporate philanthropy initiative, focuses on creating sustainable communities through water solutions and STEM education. With over $80 million in contributions since 1998, the foundation emphasizes ecological resilience, water quality improvement, and youth engagement in science and technology. They prioritize grantmaking in specific U.S. states and international regions, fostering vibrant communities and encouraging employee volunteerism. Initiatives are invitation-only, ensuring a targeted approach to impactful philanthropy.

Rolling deadline

Unspecified amount

Roche Corporate Donations and Philanthropy (CDP) focuses on impactful projects that foster sustainable development, engage employees, and leverage Roche's expertise. Their philanthropic efforts prioritize humanitarian, educational, environmental, and cultural initiatives, aiming to build stronger communities and support innovative projects. Eligibility is limited to local organizations, while ineligible projects include those with political or religious ties. The foundation strives to create a positive societal impact through collaboration and strategic partnerships.

Rolling deadline

Unspecified amount

The Sachs Family Foundation Grant aims to enhance the quality of life for economically and educationally disadvantaged individuals and families. The Foundation supports self-sustaining charitable organizations focusing on economic and educational opportunities, particularly in low-income communities in the U.S. and developing countries. Grants are available for various initiatives, including education, housing, and job training, with a keen interest in programs that demonstrate clear potential for sustainability.

Rolling deadline

Unspecified amount

The Semnani Family Foundation, established in 1993, is dedicated to supporting marginalized communities worldwide through health, education, and disaster relief initiatives. Founded by Khosrow and Ghazaleh Semnani, it began by funding an orphanage in Romania. The foundation also operates locally, providing free healthcare through the Maliheh Free Clinic in Utah. Its commitment to human welfare drives impactful partnerships in countries such as Afghanistan, India, and South Africa, focusing on the most vulnerable populations.

Rolling deadline

Unspecified amount

The Audacious Project Grant Program, supported by TED, aims to catalyze social impact by funding bold solutions to pressing global challenges. This initiative encourages changemakers to develop transformative ideas into actionable plans, with a focus on various issues, including health and education. The program operates on a rolling basis, welcoming applications from individuals and organizations with a proven track record and a budget of at least $2 million. Join us in creating lasting change for a better world.

Rolling deadline

Unspecified amount

The Tony Robbins Foundation Grant aims to empower individuals and organizations to improve the lives of marginalized communities, including youth, seniors, and the homeless. By providing financial support to aligned nonprofits, the foundation seeks to create impactful changes globally. Eligible organizations must be 501(c)(3) nonprofits or recognized international entities, with a mission statement that resonates with the foundation's goals. The foundation does not fund personal projects or startups.

Rolling deadline

Unspecified amount

The Walmart Foundation invites 501(c)(3) organizations to submit program-related concept notes focused on the Healthier Food for All initiative. This ongoing program seeks to enhance access to nutritious food in underserved communities while linking nutrition to healthcare. With a commitment to combat chronic illnesses through better nutrition, Walmart aims to fill food access gaps and promote food as medicine programs, ultimately improving health outcomes for many Americans.

Rolling deadline

Unspecified amount

The Zegar Family Foundation Grant, established in 2007, focuses on improving lives through impactful charitable donations. The foundation prioritizes areas such as environment, justice, human rights, science, education, and community development. While unsolicited proposals are not accepted, the foundation remains open to innovative ideas that align with its mission. Through targeted support, it aims to create lasting positive change in communities and promote social equity.

Applications due Mar 23, 2026

Unspecified amount

The Hansen Family Foundation Grant seeks to empower organizations that uphold the American values of life, liberty, and the pursuit of happiness. Focused on diverse causes like children, education, animals, environmental conservation, humanitarian efforts, and arts, the foundation is committed to supporting initiatives that create positive change. Eligible applicants must be 501(c)(3) nonprofits, while political campaigns and organizations with high budgets or overheads are ineligible. This grant fosters impactful contributions to society.

Applications due Apr 28, 2026

Unspecified amount

The Thriving Communities Grant Program by The New York Community Trust aims to combat climate change and enhance community resilience across multiple states. It focuses on sustainable initiatives like energy efficiency, low-emission vehicles, and habitat conservation. Additionally, it supports public health by minimizing toxic pollutants and enhancing protections for vulnerable communities. Projects should aim for regional impact, particularly those benefiting disadvantaged areas, aligning with broader goals of environmental justice and biodiversity preservation.

Pre proposal due Jul 1, 2026

Unspecified amount

The New Earth Foundation Grant aims to support innovative, humanitarian projects that promote sustainability, peace, and community development. Founded by John B. Loveland in 1997, the foundation focuses on assisting smaller 501(c)(3) organizations to create impactful solutions for societal challenges. Grants are awarded to projects that demonstrate innovation, community involvement, and the potential for replication, ensuring a lasting positive impact on both local and global scales.

Letter of inquiry due Aug 15, 2026

Unspecified amount

The John Templeton Foundation Grant Program aims to inspire awe and wonder through interdisciplinary research and public engagement. By funding bold ideas that challenge conventional thought, the foundation fosters curiosity and understanding. It supports various funding areas, including character virtue development, individual freedom, life sciences, and public engagement. The foundation seeks to create a world where individuals pursue meaningful lives, motivated by love and a desire for knowledge.

Applications due Aug 31, 2026

US $5,000 - US $250,000

The Gupta Family Foundation Grant aims to empower disadvantaged individuals by providing financial support to organizations that foster self-reliance. Headquartered in Herndon, Virginia, the foundation offers grants ranging from $5,000 to over $250,000, prioritizing smaller organizations with a strong commitment to their missions. Eligibility typically includes US-based IRS 501(c)(3) entities, with operations extending to countries like India and Kenya. The foundation emphasizes mission alignment and effective resource allocation to ensure maximum impact.

Applications due Sep 1, 2026

Unspecified amount

The Zimmer Family Foundation provides national and international grants to support religious, educational, and social programs aimed at assisting the less fortunate. Based in Sarasota, Florida, the foundation focuses on seeding short-term pilot projects with potential for self-sustainability. Eligible applicants must be 501(c)(3) IRS Tax exempt organizations, with projects that can be national or international in scope. The foundation does not fund scholarships, capital purchases, or operating support.

Applications due Oct 16, 2026

Unspecified amount

The Exploring Equitable Futures Grant Program, funded by the Robert Wood Johnson Foundation, aims to transform health equity by addressing systemic racism. It supports innovative thinkers across various fields to envision a future where health is a right for all. By exploring social, technological, and economic trends, grantees are developing solutions that challenge existing barriers to health, fostering inclusive and accountable public health systems that benefit everyone in society.

Applications due Oct 31, 2026

Unspecified amount

The Dudley T. Dougherty Foundation Grant supports nonprofit charitable organizations recognized under section 501(c)(3) of the IRS Revenue Code. Established in 2002, the foundation aims to empower groups committed to positive change, fostering respect for life and the environment. Their vision emphasizes collaboration for a better future, encouraging applicants to embody these values in their initiatives. With a focus on impactful projects, this grant is an opportunity for organizations striving to make a critical difference in our world.

Applications due Feb 20, 2027

Up to US $500,000

The Unity for Humanity Grant invites innovative creators to submit impact-driven projects that utilize real-time 3D technology. This annual grant provides funding, technical support, and marketing resources to help bring visionary ideas to life. Projects must align with UN Sustainable Development Goals and demonstrate measurable impact. Eligible submissions include prototypes across various genres, fostering a more inclusive and sustainable world. Join us in empowering changemakers to make a positive global difference.

Showing 27 of 32 results.