Best Large Grants for Nonprofit Organizations in Alabama

The Kalliopeia Foundation Grant focuses on supporting projects that foster cultural and ecological renewal through a deep reverence for the Earth. By prioritizing US-based organizations that demonstrate strong community relationships and intergenerational leadership, the foundation seeks to empower marginalized voices and traditional practices. With an emphasis on land care and Indigenous leadership, Kalliopeia aims to cultivate a resilient future where diverse ways of knowing and being thrive harmoniously with nature.

The Guin-Stanford Scholarship Fund, established by The University Church of Christ, honors J. Foy Guin, Jr. and his family. It supports graduate students pursuing a Juris Doctor at the University of Alabama School of Law or teachers seeking graduate education degrees. Applicants must demonstrate a Christian lifestyle through church involvement. Awards vary annually based on fund availability and can cover tuition, housing, and supplies. Recipients should explore additional financial resources as future funding is not guaranteed.

The Alabama State Council on the Arts offers the Arts in Education Grant to enhance arts education for PreK-12 students in Alabama. This grant supports curriculum-based projects that provide sequential learning opportunities, ensuring every student can engage with the arts. With a focus on excellence and diversity, the agency aims to promote cultural artistic expressions and increase public appreciation for the arts, benefiting both individuals and communities across the state.

The Caddell Construction Co. (DE), LLC Scholarship, established by the Central Alabama Community Foundation, offers financial assistance to college students pursuing construction-related degrees. This scholarship supports rising sophomores, juniors, and seniors, and emphasizes the importance of advancing careers in construction. Applicants must submit a college transcript, resume, career plans video, and references to be considered. This initiative underscores the foundation's commitment to enhancing educational opportunities within the community.

The SFS Fellows Grant, awarded by the Society for Freshwater Science, recognizes individuals who have made significant contributions to freshwater science research, policy, or management. Each year, up to four fellows are selected based on their sustained excellence and leadership within the field. This initiative also encourages diversity by promoting nominations from underrepresented groups and mid-career professionals. The grant fosters collaboration and participation in SFS activities, enhancing the impact of freshwater science.

Gilead North America Grants support community-informed programs that enhance healthcare for vulnerable populations. Grants are available for innovative projects addressing HIV, liver diseases, oncology, and inflammatory diseases. Applications are invited from tax-exempt nonprofits based in the U.S. who focus on health equity and community engagement. Gilead prioritizes funding for projects that demonstrate a strong capability to deliver impactful outcomes, helping to eliminate barriers to healthcare and improve access to essential services.

The Bonnie Cardone Memorial Scholarship, offered by the Women Divers Hall of Fame, awards $1,500 to a woman diver enrolled in a U.S. or Canada degree program in journalism, graphic arts, photography, or videography. This scholarship aims to support those committed to using their education to benefit the ocean environment and community, promoting greater awareness and conservation efforts. Eligible applicants must demonstrate their dedication to these fields and their potential impact on marine ecosystems.

The Alabama Power Foundation's Students to Stewards Grants support schools in Alabama by providing up to $3,500 for environmental education initiatives. This funding enhances conservation learning and creates outdoor classrooms, crucial for teaching students about preserving natural resources. Additionally, the grants can facilitate safe learning environments during COVID-19, ensuring students can continue their education while adhering to social distancing guidelines. This program empowers future generations to appreciate and care for Alabama's rich natural heritage.

The Southern SARE: Producer Grant supports farmers in conducting their own research projects to develop sustainable agricultural practices. Established in 1994, the program aims to enhance farmer profitability, promote responsible land use, and improve community quality of life. By focusing on areas like organic agriculture, sustainable marketing, and alternative crops, the grant empowers farmers to address production challenges and share valuable insights with others in the farming community, fostering a culture of sustainability and innovation.

The Dogs for Joy Grant, funded by the Joy in Childhood Foundation, supports the integration of trained facility dogs in pediatric hospitals. These dogs provide emotional support, help children cope with medical procedures, and enhance overall well-being. The program aims to increase the presence of in-residence dogs, as research highlights their positive impact on reducing anxiety and improving patient outcomes. Grants typically cover multi-year funding, promoting innovative animal-assisted therapy approaches in healthcare settings.

The E.B. Henderson Award, presented by SHAPE America, honors minority members who have demonstrated exceptional commitment to scholarship, mentorship, and advocacy for ethnic minorities within health and physical education. Established in 1885, SHAPE America serves over 200,000 professionals, promoting high-quality education standards. The award recognizes individuals who have significantly contributed to increasing the participation of underserved populations in the field. Limited to two awards annually, it highlights the importance of diversity and inclusion in health education.

The Starseed Foundation Grant offers support to 501(c)(3) organizations focused on enhancing the arts, environmental protection, literacy, and social services. Grants are available to organizations throughout the United States, with a specific emphasis on programs based in Oregon. Interested parties must first submit a Letter of Inquiry to be considered for funding. This initiative aims to improve the quality of life for underserved communities through cultural and educational enrichment.

Alabama Rural Health Transformation Program - Statewide Emergency Medical Services (EMS) Trauma and Stroke Initiative

Funding under this NOFO is intended to support the initiation and expansion of eligible Statewide EMS Trauma and Stroke Initiative projects that advance one or more of the initiative goals and align with the defined strategy category identified in Section I. Depending on the proposed scope of work, funding may support activities related to improving the capacity of EMS systems, including system development, protocol implementation, training, care coordination, and operational support necessary to improve emergency response and care coordination across EMS agencies and hospitals. This may include efforts to expand trauma and stroke response capabilities to reach additional geographic regions and/or expand statewide hospital-referral services to include additional conditions.

All funding under this opportunity is expected to be distributed through a competitive subaward process. Selected applicants will be treated as subrecipients and will be required to comply with all applicable federal, state, and programmatic requirements associated with the award. 

Funding Availability

ADECA anticipates making approximately $4,000,000 available under this NOFO, consistent with the CMS-approved Statewide EMS Trauma and Stroke Initiative budget. ADECA intends to make awards under the strategy category described in Section I. The number, size, and distribution of awards will depend on application quality, applicant readiness, geographic distribution, and other factors identified in this NOFO. 

The Dollar General Literacy Foundation offers Adult Literacy Grants to support organizations providing essential literacy services to adults. Grants of up to $10,000 are available for programs in Adult Basic Education, GED preparation, and English language acquisition. Eligible applicants include 501(c)(3) organizations, schools, and libraries located within 15 miles of a Dollar General store. The foundation aims to enhance educational opportunities and foster personal growth through literacy.

The Queer Mobilization Fund (QMF) supports community-led projects that advance Queer and Trans liberation, particularly for BIPOC individuals in the Southeastern US. Established in 2016, QMF prioritizes grassroots organizations with budgets under $300,000. The fund emphasizes rapid response funding and capacity building, aiming to empower marginalized communities often excluded from financial support. QMF does not fund groups outside the Southeast or for-profit activities, ensuring resources are directed towards those leading efforts for LGBTQ+ rights.

The FDC Foundation, established in 2008, is a private non-profit dedicated to providing grants to 501(c)(3) public charities across three main areas: Health & Nutrition, Education, and Housing. The foundation supports initiatives that improve nutrition, assist diabetic individuals, enhance early childhood development, and promote housing opportunities for those in need. However, it does not fund for-profit entities or international organizations, nor does it provide grants for specific excluded purposes.

Our Mission

The Community Foundation’s mission is to improve the quality of life in Greater Kansas City by increasing charitable giving, educating and connecting donors to community needs they care about, and leading on critical community issues.

Scholarships

We offer hundreds of different scholarships for students in and around Kansas City.

William H. Coleman, Sr. Scholarship Fund

The purpose of fund is to promote continued growth and career advancement through higher education in a nursing career to nurses and health care providers that are currently employed at Highlands Medical Center.

Application Requirements:

• Statement of Need
• Statement of Goals/Potential for Contribution
• 2 Letters of Reference
• Your School and Program (such as dates enrolled, area of study, etc.)
• Your Education, Experience, and Professional Activities/Transcript
• Validation of required employment & enrollment/intent to enroll in accredited Nursing Program of Study

The EPSCoR Research Infrastructure Improvement-Focused Collaborations Program (RII-FEC) aims to enhance research capabilities in eligible jurisdictions by fostering partnerships among government, higher education, and industry. This program supports interdisciplinary teams of researchers to tackle significant challenges in STEM fields, promoting diversity and broadening participation. By integrating Minority-Serving Institutions and early-career faculty from underrepresented backgrounds, RII-FEC seeks to build sustainable STEM capacity and drive impactful discoveries across regions.

The WGPF: Legends & Lore Marker Grant Program celebrates and promotes local folklore, legends, and folklife as vital aspects of cultural heritage. Targeted at 501(c)(3) organizations and government entities across 14 US states, it aims to enhance cultural tourism by commemorating community stories. Successful applications typically focus on folktales, historical legends, and community traditions, while excluding purely literary works or personal folklore that lacks broader community significance.

Alabama Rural Health Transformation Program - Cancer Digital Regionalization Initiative

Funding is intended to support the implementation of Cancer Digital Regionalization Initiative projects that advance the stated program goals. Depending on the proposed project, funding may support expansion of cancer detection capabilities, establishment and operation of regional screening hubs, deployment of mobile screening units, and community outreach and education to increase awareness and participation in cancer screening. These efforts are intended to strengthen local healthcare delivery systems and improve  the quality, accessibility, and sustainability of cancer screening for rural populations.

All funding under this opportunity is expected to be distributed through a competitive subaward process. Selected applicants will be treated as subrecipients and will be required to comply with all applicable federal, state, and programmatic requirements associated with the award. 

ADECA anticipates making approximately $8,100,000 available under this NOFO, consistent with the CMS-approved Cancer Digital Regionalization Initiative budget. ADECA intends to make awards under the strategy categories described in Section I. The number, size, and distribution of awards within each strategy category will depend on application quality, applicant readiness, geographic distribution, and other factors identified in this NOFO. 

The Indian Environmental General Assistance Program (GAP), administered by the U.S. Environmental Protection Agency (EPA), provides crucial funding to tribal governments and intertribal consortia for developing environmental protection programs. Since 1992, GAP has focused on remediation of pollutants and, more recently, supports climate adaptation initiatives. The program emphasizes tribal sovereignty while aiding in capacity building, policymaking, and establishing joint EPA-Tribal Environmental Plans to effectively address environmental challenges faced by tribal communities.

Tides Foundation

Tides is a partner for justice in the social sector, working closely with doers and donors to build the power of historically excluded groups who face systemic barriers. We provide fiscal sponsorship, donor advised funds, impact investing, and a variety of grantmaking solutions to advance social justice and equity. 

Through Tides Foundation, we partner with individuals and families, foundations, corporations, and social change leaders to design and deliver social impact initiatives that shift decision-making power back to the communities we serve. Our mission is our North Star — and a beacon for those who share our commitment to social justice. Together, we work to shift resources and power to communities historically denied both, so they can create a just and equitable future.

Voter Mobilization & Civic Innovation Fund

This fund is designed for organizations that are deeply rooted in community, testing bold or emerging strategies, and able to adapt quickly to changing on-the-ground conditions. The Southern Voter Mobilization & Innovation Fund is a 12-36 month, election-cycle investment designed to support organizations that are: 

• Closest to communities facing the most barriers to political participation
• Testing bold, creative, or unproven civic engagement strategies
• Shifting power to local groups participating in civic engagement
• Responding rapidly to on-the-ground conditions during the 2026 midterms 

Tier 2: Context-Dependent Areas

While we have identified priority counties based on data and historic investment patterns (Tier 1), we remain open to proposals serving other counties within the five Southern states.  

For work proposed outside of previously identified priority areas, we invite applicants to share:  

• Why this geography is urgent or strategically important at this moment 
• What gaps or opportunities exist that may not be reflected in traditional metrics 
• How this work complements- not duplicates of existing investments 

The California Casualty Music & Arts Grant supports K-12 public schools facing budget cuts that threaten their music and arts programs. Eligible applicants, who must be active employees of public K-12 schools and members of specified educator associations, can request grants of $250 for music or arts needs. This initiative aims to enhance creative education across the states, excluding AK, HI, MA, MI, NY, and WI. Applications received by July 15 will be notified by November 30.

The Alabama Research and Development Enhancement Fund (ARDEF) Program, managed by the Alabama Department of Economic and Community Affairs (ADECA), aims to stimulate research and development efforts in Alabama. By focusing on innovative projects, this program seeks to enhance employment opportunities and improve the quality of products and services available to residents. Through this initiative, Alabama aims to foster a robust research environment conducive to growth and economic development.

The Alabama State Council on the Arts offers the Community Arts Project Grant to enhance life quality and economic vitality in Alabama through diverse artistic support. This grant promotes excellence in the arts, provides educational opportunities, and encourages public engagement. Eligible projects can include festivals, performances, exhibitions, and workshops, aiming to create positive arts experiences for all Alabamians. The grant seeks to foster appreciation for the arts and recognize their role in cultural and economic development.

About Community Foundation of South Alabama

Since its inception, the Community Foundation has grown to over 500 funds and awarded over $98 million in grants and scholarships throughout the eight counties of southwest Alabama, improving the lives of many residents in our corner of the world.

We amplify the gifts from generous donors through wise investment, support others in efforts to enhance our community, and lead and collaborate on initiatives which have a broad impact.

Scholarships

The more than 40 scholarship funds at the Foundation were created by generous donors who wanted to help the students in our community achieve a brighter future. We are committed to assisting the most promising students with scholarships for professional certificate programs, two and four-year undergraduate degrees and graduate school. The scholarship funds at the Foundation award grants to high school, community college and university students to be used for tuition, books, and fees.

Gavin “Gee” Hunter Agricultural Scholarship

For a Baldwin County graduating senior or college student pursuing a degree in agriculture or related field at Auburn. Applicants must have 3.5 GPA and at least a 20 ACT score.

ADECA Domestic Violence Trust Fund

Domestic Violence Trust Fund is a state funded grant that provides funds to assist certified DV Shelters in Alabama. This program is funded through the Marriage Licenses fees that are collected throughout the State of Alabama.

In order to receive these funds, the agency must be certified through the Alabama Coalition Against Domestic Violence. The agency must provide the minimum services required under Section 30-6-6 of the Code of Alabama, which includes, but is not limited to, information and referral services, counseling and case management services, temporary emergency shelter for more than 24 hours for adult victims and their accompanying children, a 24-hour hotline, training for law enforcement personnel, assessment and appropriate referral of resident children, outreach services as defined by standards for counties without a physical emergency shelter facility, educational services for community awareness relative to the incidence of domestic violence, the prevention of domestic violence, and the care, treatment, and rehabilitation for persons engaged in or subject to domestic violence.

The Domestic Violence Trust Fund operates on the state fiscal year calendar of October 1st- September 30th. Funds are distributed to the agency each quarter. Application for this grant is due annually.