Best Large Grants for Nonprofit Organizations in Alabama

The Great Apes and Gibbons Program Grant, administered by the Arcus Foundation, supports conservation efforts for great apes and gibbons across 24 priority landscapes in Africa and Asia. The program emphasizes sustainable coexistence between humans and wildlife, having awarded over 2,000 grants to more than 500 organizations globally. Funding is not available for individuals or specific lobbying activities, ensuring resources are directed towards impactful conservation initiatives.

The Rosendin Foundation Annual Grant provides financial support to community-focused 501(c)(3) non-profit organizations across various states, aiding initiatives in emotional, occupational, and nutritional health. Grants can reach up to $50,000 and are geared towards organizations that positively impact their communities. However, the foundation does not fund discriminatory practices, political efforts, or religiously affiliated projects, ensuring that support is directed towards inclusive and impactful community services.

The Ernest Morgan Memorial Scholarship, managed by CommunityGiving, supports central Minnesota student athletes and leaders to pursue higher education outside their home states. This scholarship aims to expand students' horizons and experiences, with a total award of $5,000 available. Open to high school seniors from specific schools, applicants are encouraged to apply online and demonstrate their leadership or athletic skills. This initiative enhances educational opportunities and fosters personal growth among local youth.

The AL Emergency Watershed Protection (EWP) Program provides vital technical and financial assistance to local communities facing imminent threats from natural disasters such as floods and fires. It aims to relieve hazards to life and property without requiring a federal or state disaster declaration. The program enables local sponsors to initiate emergency actions to restore watersheds and ensure that projects meet engineering standards while promoting economic and environmental sustainability.

The Patient-Centered Outcomes Research Institute (PCORI) intends to issue a Broad Pragmatic Studies (BPS) PCORI Funding Announcement (PFA) on Aug. 4, 2026, seeking to fund high-impact, patient-centered comparative clinical effectiveness research (CER) projects. This preannouncement provides potential applicants additional time to identify collaborators; obtain patient and stakeholder input on potential studies; and develop responsive, high-quality applications. 

Patient-centered CER compares at least two available health treatments, services or care delivery strategies. PCORI seeks proposals that compare clinical interventions (e.g., pharmacological and nonpharmacological treatments, screening and diagnostic approaches) and healthcare delivery system interventions (e.g., workforce, technologies, healthcare service delivery designs) to evaluate potential benefits and harms of different treatment and care delivery options, thus generating evidence that empowers patients, caregivers and the broader healthcare community with information to make informed choices that reflect their needs and preferences. 

About PCORI

PCORI funds patient-centered comparative clinical effectiveness research (CER).

Our Mission

PCORI helps people make informed healthcare decisions, and improves healthcare delivery and outcomes, by producing and promoting high-integrity, evidence-based information that comes from research guided by patients, caregivers, and the broader healthcare community.

Broad Pragmatic Studies PCORI Funding

The Patient-Centered Outcomes Research Institute (PCORI) intends to issue a Broad Pragmatic Studies (BPS) PCORI Funding Announcement (PFA), seeking to fund patient-centered comparative clinical effectiveness research (CER) projects. 

Research Initiative Highlights

CER compares at least two available health treatments, services or care delivery strategies. PCORI seeks proposals that compare clinical interventions (e.g., pharmacological and nonpharmacological treatments, screening and diagnostic approaches) and healthcare delivery system interventions (e.g., workforce, technologies, healthcare service delivery designs) to evaluate potential benefits and harms of different treatment and care delivery options, thus generating evidence that empowers patients, caregivers and the broader healthcare community with information to make informed choices that reflect their needs and preferences.

Special Areas of Emphasis

For Cycle 2 2026, PCORI is particularly interested in submissions that address the following Special Areas of Emphasis (SAE) within the BPS funding opportunity. The purpose of identifying these SAEs is to encourage submissions to these areas, rather than limiting submissions to these topics. Applicants addressing one of the below SAEs should identify the area that is best associated with their research approach:  

• Addressing Obesity
• Diabetes Prevention, Care and Treatment
• Management of Urogynecological and Pelvic Pain
• Pain Management for Individuals Living With Sickle Cell Disease

In PCORI-funded research, patients and other research partners are expected to meaningfully contribute their lived experience or professional expertise to ensure studies are patient-centered, relevant and useful for healthcare decision making. Applicants must address PCORI’s Foundational Expectations for Partnerships in Research — an evidence-based framework supported by tools and resources to guide effective engagement strategies. Applicants are also strongly encouraged to consider the inclusion of a broad range of patient-centered burdens and economic outcomes. 

Broad Pragmatic Studies PFA: Category 1, Category 2 and Category 3 Study Specifications

PCORI will commit up to $120 million in direct costs through this funding opportunity. This funding opportunity contains three categories for funding:

• Category 1: Category 1 will support research projects with direct costs up to and including $5 million.

• Category 2: Category 2 will support research projects with direct costs greater than $5 million and up to a maximum of $12 million. Applications for funding under Category 2 will be required to provide additional information in the Letter of Intent (LOI) and application to justify the size and scope of the proposed research projects and to explain how additional funds are necessary with respect to the scale, scope and complexity of personnel and material resources needed to address the research question.

• Category 3: Category 3 will support research projects with direct costs up to $12 million that utilize PCORnet® to conduct observational studies and/or pragmatic trials that are national in scale. Category 3 PCORnet Studies® must include two or more Clinical Research Networks and share study progress, performance metrics and best practices with the network to promote continuous learning and improvement. PCORnet Studies® will leverage the PCORnet Common Data Model® as appropriate. Additional details about Category 3 can be found on the PCORI website.  

The EBSCO Community Impact Grant Program supports initiatives in education, environment, human services, and arts and culture. This grant is available to 501(c)(3) organizations serving specific counties in Alabama. Applicants may submit a Letter of Inquiry, but full proposals are by invitation only. EBSCO is dedicated to enhancing community well-being through innovative programs that promote equitable education, environmental protection, and access to basic human services.

The Delta Foundation, established by CFD Research Corporation in 2021, aims to enhance community well-being through collective employee-owner contributions. By funding local non-profit organizations, the Foundation supports vital initiatives in arts, mental health, and basic needs, ensuring that every dollar directly benefits the Huntsville area. The Foundation prioritizes organizations that align with its mission to improve quality of life, fostering impactful change through collaboration and community engagement.

About the Alabama Dept of Conservation & Natural Resources

Department of Conservation and Natural Resources

The Department of Conservation and Natural Resources is an executive and administrative department of the State of Alabama created by statute. The Commissioner, appointed by the Governor as a member of the Cabinet, advises the Governor and Legislature on the management of freshwater fish, wildlife, marine resources, state lands, state parks, and other natural resources. 

The Department has four divisions: Marine Resources, State Lands, State Parks, and Wildlife and Freshwater Fisheries.

Public Notice - Request for Proposals: Marketing, Communications, Media Outreach, Event Management, and Related Services

Section 1: Purpose and Summary of Services

The Alabama Department of Conservation and Natural Resources (DCNR) - State Parks Division - (PARKS) requests submissions of sealed proposals from qualified marketing and communications firms to provide the services outlined herein as requested by PARKS.

PARKS seeks to implement a comprehensive marketing and communications strategy that promotes public awareness and engagement, organizes special events, increases visitation, and enhances the overall brand identity of Alabama State Parks, with the goal of increasing attendance and bolstering their economic impact to the State of Alabama.

This RFP contains a scope of services and deliverables for a fully-integrated marketing and communications firms)

("Offeror") to assist PARKS in creating and implementing a large-scale and cost-effective program that will engage and inform the general public, stakeholder professionals and organizations, the media, and others. The firm(s) must be registered in the State of Alabama and work closely with PARKS to successfully provide these services statewide.

The Watson-Brown Foundation Grant supports organizations dedicated to preserving the history and culture of the South. It offers various types of grants, including for educational programming and historic preservation, with a focus on southern studies. Eligible recipients include public charities in the southeastern United States. The Foundation's Junior Board of Trustees also awards grants to preservation projects in east central Georgia, emphasizing youth engagement in cultural heritage.

The Comer Education Grant, established by the Comer Foundation in 1946, has allocated over $34.6 million to support educational initiatives in Alabama. Rooted in the legacy of Governor Braxton Bragg Comer, the foundation prioritizes scholarships and community improvements, particularly in areas where Avondale Mills operated. This commitment to education and social betterment reflects the family's dedication to enhancing the quality of life and opportunities for residents in Jefferson, Talladega, and Barbour Counties.

The Marvin R. and Pearl E. Patterson Family Fund Scholarship, offered by the Grand Haven Area Community Foundation, supports students aspiring to study graphic or fine arts, as well as those interested in environmental sciences. Open to high school graduates from the Tri-Cities area, this scholarship considers leadership, community involvement, and academic achievements, although financial need is not a requirement. Applicants must provide transcripts and relevant documents to qualify for this opportunity.

The Sidney B. Meadows Scholarship, established in 1989, offers financial support to students pursuing degrees in horticulture across 16 southeastern states. Administered by the Sidney B. Meadows Scholarship Endowment Fund, this scholarship honors the legacy of Sidney B. Meadows, a dedicated advocate for education in the horticultural industry. Applicants must meet specific eligibility criteria related to academic standing and residency, with preference given to those intending to work in the field after graduation.

The Southern Partners Fund's Discretionary Fund Grant aims to support grassroots community organizing for social, economic, and environmental justice in the Southeastern United States. It provides financial resources and technical assistance to rural organizations and leaders focused on transformative change. Eligible applicants include self-governed rural groups engaging in advocacy and community development. The fund prioritizes education reform, immigration rights, and voter engagement, allowing up to two requests per year, with a maximum award of $3,500.

The Abelard Foundation, established in 1958, supports progressive social change projects located east of the Mississippi River. With an average grant size of $12,000, they prioritize new initiatives with budgets under $350,000. The foundation emphasizes community organizing, civil rights, and empowering marginalized groups. Eligible applicants must be associated with a nonprofit organization and demonstrate a commitment to local leadership and broader policy connections. The board meets biannually to decide on approximately 15 grants per year, focusing mainly on general support.

The Enbridge Community Grant aims to enhance the quality of life in North American communities through strategic donations and sponsorships. With funding ranging from $1,000 to $10,000, the grant supports organizations focused on safety, education, environmental stewardship, and Indigenous culture. Enbridge encourages early applications, with decisions typically made within eight weeks. The grant seeks to empower local initiatives that foster community strength, vibrancy, and sustainability.

The Growing Tribal Economies Through Forest Market Innovations grant program, initiated by First Nations Development Institute, aims to empower Tribes and Alaska Native Villages to engage in emerging markets that enhance forest health and resilience. With funding of $200,000 to $500,000 per grant, this initiative supports projects focusing on sustainability, innovation, and traditional knowledge. Eligible applicants are encouraged to develop forest products, certifications, and practices that contribute positively to biodiversity and ecosystem management.

2026 Specialty Crop Block Grant Program (SCBGP)

The Alabama Department of Agriculture & Industries (ADAI) receives grant funding from the United States Department of Agriculture (USDA) to enhance the competitiveness of Alabama's specialty crops. ADAI accepts competitive applications for specialty crop grant funds annually.

Solely enhance the competitiveness of US specialty crops

To be eligible for a grant, the project(s) must "solely enhance the competitiveness of US specialty crops" in either domestic or foreign markets.

The Anderson-Rogers Foundation Grant supports U.S.-based 501(c)(3) organizations focused on environmental protection, animal welfare, climate change mitigation, and social support. Established in 2001, this family foundation prioritizes innovative projects and general operating support for small organizations facing financial constraints. Note that applicants must first submit a letter of inquiry, as the foundation does not fund scholarships or grants to individuals or religious organizations, nor does it support organizations outside the U.S.

Tides Foundation

Tides is a partner for justice in the social sector, working closely with doers and donors to build the power of historically excluded groups who face systemic barriers. We provide fiscal sponsorship, donor advised funds, impact investing, and a variety of grantmaking solutions to advance social justice and equity. 

Through Tides Foundation, we partner with individuals and families, foundations, corporations, and social change leaders to design and deliver social impact initiatives that shift decision-making power back to the communities we serve. Our mission is our North Star — and a beacon for those who share our commitment to social justice. Together, we work to shift resources and power to communities historically denied both, so they can create a just and equitable future.

Multi-Year Accelerator Grant

The Vote Your Voice Accelerator Infrastructure Fund is a multiyear investment in trusted, high-capacity, and deeply networked civic-engagement organizations across: Georgia, Alabama, Florida, Louisiana, and Mississippi. This fund is designed to: 

• Stabilize and sustain the organizations carrying the long-term weight of democracy protection 
• Strengthen the connective tissue across state and regional ecosystems 
• Support innovation, adaptation, and emergent learning in shifting political conditions 
• Ensure frontline communities remain centered in voter engagement, protection, and shifting power to those historically denied it

The Alabama Power Foundation's Good Roots Grants provide up to $1,000 for tree planting in public spaces across central and south Alabama. This initiative, in partnership with the Alabama Urban Forestry Association, aims to enhance community beauty, improve environmental quality, and promote active involvement. By funding tree planting projects, the foundation seeks to create cooler neighborhoods, reduce energy costs, and foster a sense of community, ensuring Alabama remains vibrant and green.

The Mazamas is committed to exploring and preserving mountain environments in the Pacific Northwest through research grants. These grants support nonprofit research that aligns with the Mazamas’ mission, encouraging proposals from graduate and undergraduate students. Successful applicants often conduct field studies that enhance understanding of the region's natural features. Notably, the Mazamas also welcome innovative research ideas that may fall outside traditional grant guidelines, promoting a diverse range of scientific inquiry.

The Alabama Power Foundation's Elevate Grant aims to enhance the quality of life for Alabamians by empowering nonprofits to address pressing community needs. Focused on workforce development and removing barriers to success, this initiative supports organizations that exhibit strong fiscal management and accountability, while also targeting underserved populations. By providing tools and resources, the Elevate Grant strengthens nonprofits to expand their impact across Alabama, ensuring a brighter future for all.

Entergy’s Open Grants Program aims to enhance community well-being through funding initiatives in arts, education, social services, and community improvement. The program prioritizes support for organizations that serve diverse populations, including children and low-income communities. Eligible entities must have 501(c)(3) status or equivalent nonprofit recognition. Applications should be submitted three months in advance, allowing ample time for review. Entergy focuses on projects that foster self-sufficiency and enrich local neighborhoods.

The Agricultural Conservation Easement Program (ACEP) in Alabama focuses on Wetland Reserve Easements (WRE) to support landowners in protecting and restoring wetlands degraded by agricultural activities. This program not only enhances habitat for wildlife, including endangered species, but also improves water quality and reduces flooding. Through various enrollment options, NRCS offers financial assistance for easement purchases and restoration costs, ensuring that eligible land can be effectively restored for agricultural and conservation purposes.

The Catholic School Leadership Development Grant Program aims to cultivate and retain promising leaders within the Catholic school system. In partnership with Loyola Marymount University, this initiative offers a graduate-level online Certificate in Catholic School Administration, covering 80% of tuition costs and providing funding for essential travel. The one-year program focuses on mission effectiveness, operational management, and instructional leadership, requiring participants to serve two years in their diocese post-completion, thereby enhancing local educational leadership.

About Us

advancing the science of water ®

Who We Are

The Water Research Foundation (WRF) is the leading research organization advancing the science of all water to meet the evolving needs of its subscribers and the water sector. WRF is a 501(c)(3) nonprofit, educational organization that funds, manages, and publishes research on the technology, operation, and management of drinking water, wastewater, reuse, and stormwater systems—all in pursuit of ensuring water quality and improving water services to the public.

5430 - Unlocking Value and Opportunities from Carbon Flows in Water Utilities

Grant Information

• Identify carbon flows across drinking water, stormwater, wastewater, and advanced treatment systems. Carbon flows may include source water, stormwater, process emissions, process inputs, residuals, and biogas.
• Identify the most relevant carbon recovery, capture, conversion, storage, and avoidance opportunities.
• Evaluate value creation pathways, including products, avoided costs, and environmental attributes, and mechanisms and partnerships needed to put them into practice.
• Assess how opportunities vary across system types and local contexts by focusing on more common scenarios for utilities.
• Provide practical, research-based insights to support identification, prioritization, evaluation, and advancement of carbon management opportunities under site-specific conditions and constraints.
• Evaluate implications for greenhouse gas (GHG) accounting, environmental attribute claims, and other potential benefits across pathways.