Best Boston Grants for Nonprofits in Massachusetts

The MassCEC CriticalMass Program supports growth-stage climatetech startups by providing up to $1,000,000 in grant funding, specialized services, and partner matchmaking. This initiative aims to address significant challenges such as capital needs and regulatory complexities faced by these startups. By proposing projects that tackle decarbonization challenges, successful applicants will contribute to the advancement of Massachusetts' clean energy economy and help establish the state as a leader in climate innovation.

The DARPA Tactical Technology Office (TTO) seeks innovative proposals to enhance national security through cutting-edge technology. This initiative focuses on Design/Build/Buy, Surge and Sustain, Long Range Effects, and Disruptive Innovation. By fostering rapid adaptation and sustainable force structures, TTO aims to demonstrate revolutionary systems that are not only effective but also affordable and responsive to emerging challenges.

The Outdoor Fund - Local Impact Grant supports local organizations and projects that enhance community engagement and align with conservation goals. With grants up to $5,000, eligible projects include youth fishing clinics and trail maintenance. Funded by Bass Pro Shops and Cabela’s, this initiative exemplifies their commitment to wildlife conservation and connecting communities to the outdoors. Eligible applicants include municipalities and registered nonprofits in the U.S. and Canada, focusing on specific conservation efforts.

Bass Pro Shops & Cabela's Outdoor Fund supports conservation-focused nonprofits through fundraising events and donation of merchandise or gift cards. Organizations eligible for funding must be registered 501(c)(3) entities in the U.S. or provincially registered nonprofits in Canada. This initiative aims to connect communities to outdoor activities while promoting wildlife conservation and support for military veterans. Grants of up to $1,000 are available to enhance local fundraising efforts.

The First Responders Outreach (FRO) Grant, provided by the Gary Sinise Foundation, supports essential resources for firefighters, police, and EMTs. This grant specifically targets First Responder Departments, allowing one application per year focused on equipment and training. It excludes funding for building costs and weaponry. This initiative aims to enhance the safety and preparedness of those who protect our communities during emergencies, ensuring they have the necessary tools and training to perform their vital roles effectively.

The 9.11 Promise Run Scholarships provide financial support to children of first responders and military personnel who have been killed or injured. Established in 2019, these scholarships range from $5,000 to $15,000 and can be applied toward trade school or college tuition. Eligible applicants must be under 25 years old and maintain a minimum GPA of 2.0. Awards are issued directly to accredited institutions and can be renewed for up to six years, ensuring continued support for eligible students.

The H. Hovnanian Family Foundation Grant supports the Armenian community in Armenia and the U.S., focusing on Monmouth and Ocean Counties, New Jersey. The Foundation prioritizes education, healthcare, arts, and youth development through grants to registered non-profits. Proposals should demonstrate sustainability and community impact, with favorable consideration given to projects that engage local stakeholders and foster collaboration. Applications are accepted year-round, with a maximum funding limit of $10,000 for operational expenses.

The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) is announcing a Notice of Funding Opportunity (NOFO) for Diabetes Research Centers (DRCs). These centers aim to foster collaboration among diabetes researchers, enhance preclinical and clinical research, and provide access to specialized resources. Emphasis is on innovative scientific themes and collaborative projects in areas such as Immunology and Artificial Intelligence. Although applications are not currently solicited, potential applicants are encouraged to prepare for future submissions.

The Arkansas Audubon Society Trust Grants support conservation, research, and education projects focused on Arkansas bird species and their habitats. Established in 1972, the trust offers grants ranging from $100 to $1200, prioritizing projects within the state but considering broader initiatives as well. Eligible applicants include individuals, students, educators, and nonprofits. Proposals are accepted biannually, with meetings held to discuss funding decisions, fostering a community dedicated to avian conservation.

The Abbvie Parkinson’s Disease Grant aims to enhance the understanding and management of subcutaneous infusion therapies for advanced Parkinson’s disease. As these therapies become more prevalent, it is crucial for Movement Disorder Specialists and General Neurologists to develop confidence in identifying, mitigating, and managing infusion site events. This grant seeks to provide essential education and resources to support safe and effective treatment options for patients experiencing motor fluctuations.

The BioMarin Grant aims to support events, activities, and projects that enhance public health and benefit patients with rare diseases. This corporate funder focuses on scientific innovation and provides resources for organizations such as hospitals, universities, and patient advocacy groups. With an emphasis on education and community support, BioMarin encourages applications for funding throughout the year, ensuring timely assistance for eligible projects.

The BioMarin Medical Education Grant offers funding for educational activities aimed at enhancing the knowledge and skills of healthcare professionals. Eligible applicants include accredited providers, medical associations, and patient advocacy groups. The grant focuses on supporting initiatives related to rare diseases, ensuring timely access to treatments and education. Applications are accepted year-round, but a minimum of 60 days is required for review prior to events. This commitment underscores BioMarin's dedication to improving patient care and advancing medical knowledge.

BioMarin offers funding through its donation program focused on improving healthcare and patient advocacy, particularly for rare diseases. Organizations eligible for support include hospitals, accredited providers, and patient advocacy groups. BioMarin prioritizes innovative therapeutic solutions for rare genetic conditions. The company is dedicated to enhancing patient care and education, and it reviews funding requests year-round, although specific deadlines apply for year-end funding. This initiative reflects BioMarin's commitment to addressing unmet medical needs.

The Strategic Projects: Capital Grants by the M J Murdock Charitable Trust offer vital funding opportunities for nonprofit organizations in the Pacific Northwest. These grants support transformative projects that enhance community well-being through construction, renovation, and infrastructure investments. Eligible entities include 501(c)(3) nonprofits and government entities. The Trust emphasizes projects that demonstrate strong community impact and funding diversification, ensuring sustainable growth and lasting benefits for the communities served.

The M J Murdock Charitable Trust offers Strategic Projects: Equipment & Technology Grants to nonprofits in the Pacific Northwest. These grants focus on capacity-building projects and essential equipment, requiring recipients to cover at least 50% of costs. Eligible organizations include 501(c)(3) nonprofits and tribal entities. Priority is given to projects enhancing community services, education, and environmental stewardship, supporting initiatives that foster human flourishing and demonstrate diversified funding.

The EmPower Massachusetts Implementation Grants, offered by the Massachusetts Clean Energy Center (MassCEC), provide funding to enhance energy access for underserved communities. Grants range from $50,000 to $150,000 and are aimed at implementing community-based projects that address energy burdens. This initiative supports innovative solutions and strengthens organizational capacity, ultimately contributing to the Commonwealth’s clean energy goals and fostering equitable access to clean energy benefits.

The Society of Family Planning is offering the Bridging Investments in Abortion and Contraception Research Grant to support the completion of NIH grants focused on abortion and contraception. This funding aims to mitigate the impact of recent funding terminations by ensuring that vital research continues, promoting equitable access to reproductive health. Proposals can request up to $100,000 and must detail their alignment with the Society's mission, planned activities, and budget within a 24-month timeline.

The Slomo and Cindy Silvian Foundation Grant supports a range of subjects including education, children's welfare, medical care, medical research, and Jewish philanthropic endeavors. Established in honor of Cindy Silvian, the foundation has awarded over $30 million since 2008. Applications are by invitation only, and organizations must meet specific eligibility criteria to be considered for funding. This year, the foundation allocated over $2.4 million to more than 110 organizations, highlighting its commitment to impactful philanthropy.

This Notice of Funding Opportunity (NOFO) is one of three NOFOs for the National Cancer Institute (NCI) Community Oncology Research Program (NCORP). NCORP is designed to enhance generalizability and dissemination of clinical trial results through accrual in a variety of community settings. The purpose of NCORP is to engage cancer patient populations, those at risk of cancer, and organizations in rigorous studies focused on cancer control, prevention, treatment and care delivery.NCORP will support the following components that will be individually awarded through the respective RFAs indicated below:

• NCORP Research Bases (UG1 Clinical Trials Required);
• NCORP Community Sites (UG1 Clinical Trials Not Allowed); and
• NCORP Academic Community Sites (UG1 Clinical Trials Not Allowed)

NCORP Community Sites are consortia of community hospitals and/or oncology practices, which may or may not be formally affiliated in a healthcare system, that accrues participants to cancer control, prevention, treatment and care delivery clinical trials and other human subjects research.

The Avant Garde Award supports innovative research on HIV and substance use disorders, encouraging creative scientists to explore high-risk, high-reward approaches. While applications are not currently being accepted, this initiative by the National Institute on Drug Abuse (NIDA) aims to stimulate collaborations and impactful research. Early-stage investigators are particularly encouraged to consider this opportunity as they develop their proposals for future funding. The program uses the DP1 activity code, fostering transformative advancements in biomedical and behavioral science.

This Notice of Funding Opportunity (NOFO) is one of three NOFOs for the National Cancer Institute (NCI) Community Oncology Research Program (NCORP). NCORP is designed to enhance generalizability and dissemination of clinical trial results through accrual in a variety of community settings. The purpose of NCORP is to engage cancer patient populations, those at risk of cancer, and organizations in rigorous studies focused on cancer control, prevention, treatment and care delivery. NCORP will support the following components that will be individually awarded through the respective Request for Applications (RFAs) indicated below:

• NCORP Research Bases (UG1 Clinical Trials Required);
• NCORP Community Sites (UG1 Clinical Trials Not Allowed); and
• NCORP Academic Community Sites (UG1 Clinical Trials Not Allowed)

The NIH Science Education Partnership Award (SEPA) fosters innovative educational initiatives aimed at pre-college students, promoting their interest in STEM fields, especially in biomedical and behavioral sciences. This program supports both classroom projects and informal science education activities, such as after-school programs and library events. Emphasizing the development of quantitative and computational skills, SEPA seeks to inspire the next generation of scientists and thinkers through engaging educational experiences.

This funding opportunity aims to support innovative research projects targeting previously undruggable classes of proteins associated with challenging human diseases. By encouraging early-stage exploratory projects, it seeks to foster the development of novel methods and agents that can selectively modulate these hard-to-target proteins, ultimately advancing therapeutic strategies and improving patient outcomes.

The Greenpoint Foundation Grant aims to enhance community life by supporting organizations that focus on agriculture, food security, education, and community enhancement. Established in 2022, the Foundation accepts grant applications year-round for both general operating budgets and specific projects. Priority is given to 501(c)(3) organizations and local government entities, while faith-based programs are considered on a case-by-case basis. Grant recipients must submit impact reports to ensure continued support.

The Good Neighbor Firefighter Safety Program Grant, initiated by State Farm and the National Volunteer Fire Council, aims to support volunteer fire departments in acquiring critical safety equipment. In 2025, the program will award $1.5 million in grants, providing $10,000 each to 150 eligible departments. This initiative not only enhances firefighter safety and operational efficiency but also fosters community service, ensuring that these departments are well-equipped to respond effectively to emergencies.

The Bertin Family Foundation Grants support 501(c)(3) public charities that align with the foundation's mission of community strengthening and compassion. Grant requests are accepted annually from July 1 to August 31, focusing on program or project support rather than general endowment. The foundation values measurable outcomes and responsible stewardship, and gives preference to organizations with Gold or Platinum status on Candid.

The Store-Based Giving Program by Ross Stores Foundation supports socioeconomically disadvantaged youth by providing gift cards for school or professional clothing. Organizations must be federal tax-exempt and serve at least 60% low-income youth. Eligible programs include academic achievement and life skills initiatives. Award amounts typically range from $300 to $500, depending on budget and mission alignment. Applications are not accepted from organizations that have received donations within the past 12 months.