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Best Buffalo County Grants for Nonprofits in South Dakota

Looking for grants for 501(c)(3) nonprofit organizations working in Buffalo County, South Dakota? Find the perfect grant for your nonprofit on Instrumentl.

9,000+

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$3.82B

Total funding

$5K

Median grant

9,000+ grants
$3.82B total
$5K median

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9,007 Results based on applied filters

Preventing Suicide and Interpersonal Violence Among Youth and Young Adults

Dept. of Health & Human Services: Centers for Disease Control & Prevention
Federal Government
American Samoa, Guam +4 more
Up to US $500,000
The CDC's National Center for Injury Prevention and Control invites research proposals aimed at reducing suicide and interpersonal violence among youth aged 10 to 24. This funding opportunity encourages the evaluation of pre-existing primary prevention strategies that have not yet been rigorously assessed. Proposed approaches may include community programs and policies designed to enhance social connectedness, mitigate harmful online behaviors, and address technology-facilitated interpersonal violence.
Youth Services Suicide Prevention

Tobacco Centers of Regulatory Science (TCORS) (Clinical Trial Optional)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Tobacco Centers of Regulatory Science (TCORS) program, supported by the NIH and FDA, aims to foster research centers that enhance the scientific understanding of tobacco regulation. These centers will conduct hypothesis-driven projects on critical topics such as addiction, health effects, and marketing. By providing a multidisciplinary approach, TCORS seeks to inform public health strategies and ensure effective implementation of the Family Smoking Prevention and Tobacco Control Act.
Addiction & Substance Use Disorders

National Viral Hepatitis Education, Awareness, and Capacity Building for Communities and Providers

Dept. of Health & Human Services: Centers for Disease Control & Prevention
Federal Government
American Samoa, Guam +4 more
Unspecified amount
This funding opportunity seeks to enhance awareness and education on viral hepatitis among high-risk populations and healthcare professionals. It focuses on two components: community education and professional training. By fostering coalitions and providing resources, the initiative aims to improve testing, treatment, and care for hepatitis B and C, ultimately reducing morbidity and mortality linked to these infections. The goal is to empower communities and healthcare providers with the knowledge and tools needed for effective prevention and intervention.
Epidemiology & Public Health Liver Disease Hepatitis B

Research Grants to Rigorously Evaluate Innovative and Promising Approaches to Prevent Firearm-Related Violence and Injuries

Dept. of Health & Human Services: Centers for Disease Control & Prevention
Federal Government
American Samoa, Guam +4 more
Up to US $650,000
The CDC's NCIPC invites research proposals to evaluate innovative approaches for preventing firearm-related violence and injuries. This initiative emphasizes the importance of data-driven solutions without infringing on legal firearm ownership rights. Funding options are available for existing data evaluations (up to $350,000/year for 2 years) or new data collection (up to $650,000/year for 3 years). Target areas include mass shootings, suicides, and crime prevention across various demographics and settings.
Violence Prevention Gun Violence Prevention

Rotary Club of Gulfport Scholarship Endowment Fund

Gulf Coast Community Foundation Inc
Private
United States
Up to US $8,000

Rotary Club of Gulfport Scholarship Endowment Fund

The Rotary Club of Gulfport Scholarship Endowment Fund is funded by the Rotary Club of Gulfport and was established in February 1997 for the purpose of providing scholarship assistance to graduating seniors of Gulfport High School, St. Patrick Catholic High School, West Harrison High School and Harrison Central High School in recognition of their academic accomplishments. Applicants must be a resident of the city of Gulfport.

Education - Higher Education Career / College Preparation

Rotary Club of Biloxi Scholarship Endowment Fund

Gulf Coast Community Foundation Inc
Private
United States
Unspecified amount

Rotary Club of Biloxi Scholarship Endowment Fund

The Rotary Club of Biloxi Scholarship Endowment Fund was established in June 1999. This scholarship is funded by the Rotary Club of Biloxi for the purpose of providing scholarship assistance to a graduating senior of Biloxi High School, St. Patrick Catholic High School, D’Iberville High School, or the Mississippi School of Math and Science, or a homeschool senior student registered with the County Attendance Office and whose parent or legal guardian resides in Biloxi.

Education - Higher Education Career / College Preparation

Association of North Texas Construction Professionals (ANTCP) Scholarship

Wichita Falls Area Community Foundation
Private
United States
US $1,500

Wichita Falls Area Community Foundation

For over 25 years, the Community Foundation has remained committed to leaving a legacy for future generations by promoting philanthropy, providing charitable opportunities, and facilitating donors’ interests. We work alongside donors and community partners to help meet area needs, create solutions, and inspire action to build a vibrant community today and a stronger community for tomorrow. 

Scholarships

The Community Foundation is home to 50 scholarship funds established by generous individuals, organizations and businesses to help students from our community and surrounding areas pursue their dreams through education. 

Association of North Texas Construction Professionals (ANTCP) Scholarship

The Association of North Texas Construction Professionals (ANTCP) Scholarship was opened in 2020. The ANTCP Scholarship is for students who are engaged in, OR whose family members have been engaged in, a construction trade. It is open to current college students residing in, OR graduating seniors of high schools in, Wichita, Archer, Clay or Wilbarger counties. There are (2) $1,500 ANTCP scholarships available each year, they can be used for any field of study at a 4-year college in the US, renewable for up to 4 years with a 2.5 cumulative GPA, OR a one-time scholarship for any vocational/trade program in the U.S.

Vocational & Trade Education Education - Higher Education

Bill Mahoney Memorial Scholarship

Wichita Falls Area Community Foundation
Private
United States
US $1,000 - US $4,000

Wichita Falls Area Community Foundation

For over 25 years, the Community Foundation has remained committed to leaving a legacy for future generations by promoting philanthropy, providing charitable opportunities, and facilitating donors’ interests. We work alongside donors and community partners to help meet area needs, create solutions, and inspire action to build a vibrant community today and a stronger community for tomorrow. 

Scholarships

The Community Foundation is home to 50 scholarship funds established by generous individuals, organizations and businesses to help students from our community and surrounding areas pursue their dreams through education. 

Bill Mahoney Memorial Scholarship

The Bill Mahoney Memorial Scholarship was opened in 2021 by Bill's daughter, Mandy, to honor her father's memory. Mr. Mahoney was a long-time teacher of the Arts at Hirschi High School in Wichita Falls. This one-time scholarship, ranging from $1,000 to $4,000, is for graduating seniors of WFISD attending any college, university, or vocational school and majoring in the Arts. Recipient must be a U.S. citizen.

Education - Higher Education Vocational & Trade Education

Margaret “Margo” Kaler Langohr Art Scholarship

Community Foundation of Whitley County
Association/Society
United States
Unspecified amount
The Margaret 'Margo' Kaler Langohr Art Scholarship, established by Margo to support Whitley County students pursuing art education, reflects her dedication to the arts. A former educator, Margo, despite her declining eyesight, created inspiring works, including 'May Your Light Shine Through My Darkness.' This scholarship aims to empower students aspiring for a Bachelor's or Associate's Degree in an art-related field at accredited institutions.
Education - Higher Education Academic Scholarship Programs Arts / Culture Access & Participation

McCasland Foundation Scholarship

Communities Foundation of Oklahoma
Private
United States
Unspecified amount

Communities Foundation of Oklahoma

The Communities Foundation of Oklahoma stems from the vision of Tom McCasland Jr., and Gene Rainbolt. Two decades ago, these gentlemen formed a shared vision to create a single philanthropic organization to serve the charitable needs to rural communities across the great state of Oklahoma. Today, CFO has grown to assist hundreds of efforts in more than 45 counties.

Scholarship Opportunities

CFO offers over 100 diverse scholarship opportunities, empowering students across the state to pursue their educational goals. Each scholarship is tailored to meet unique needs, making higher education more accessible for all.

McCasland Foundation Scholarship

Provides a scholarship to graduating seniors in Stephens County who has a minimum GPA of 2.5 and demonstrates character, leadership and participation in school activities. In partnership with The McCasland Foundation.

Education - Higher Education

Steuben County Vocational Education Scholarship

Steuben County Community Foundation
Private
United States
Unspecified amount

Steuben County Community Foundation

The Steuben County Community Foundation plays a unique role in making this community the best it can be for the people who call it home. We believe that through our work, our community members can live the lives they’ve always dreamed of. They’ll pay it forward, lift one another up, and make our community even better. Investing in our community today, positions it for a brighter tomorrow.

Steuben County Vocational Education Scholarship

The Steuben County Vocational Education Scholarship is available for Steuben County residents seeking some form of vocational training. In addition to graduates, current high school students are eligible to apply for this funding.

Vocational & Trade Education

Bridge2AI Network for AI Health Science

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
US $1,000,000 - US $7,000,000
The NIH Common Fund is planning to issue a NOFO to continue the Bridge2AI program, which aims to develop AI-ready datasets and best practices for biomedical research. This next stage will leverage these datasets to address significant health challenges and foster multidisciplinary collaboration. The initiative will support 3-5 Centers focused on trustworthy AI in biomedical research, creating frameworks for reproducibility, transparency, and advancing the AI workforce in health sciences.
Science Health & Medicine Artificial Intelligence (AI)

Health Workforce Research Center (HWRC)

US HHS: Health Resources & Services Administration (HRSA)
Federal Government
American Samoa, Guam +4 more
US $450,000 - US $900,000
The Health Workforce Research Center (HWRC) aims to enhance understanding of health workforce needs across various levels of governance. Funded by the US HHS: Health Resources & Services Administration (HRSA), this initiative supports vital research that informs decision-makers, ensuring effective resource allocation and workforce planning to meet healthcare demands.
Health & Medicine Workforce Preparation & Job Readiness

Identify and Evaluate Potential Risk Factors for Amyotrophic Lateral Sclerosis (ALS) (363115)

Dept. of Health & Human Services: Centers for Disease Control & Prevention
Federal Government
American Samoa, Guam +4 more
Up to US $500,000
The CDC/ATSDR is seeking research proposals focused on identifying and evaluating risk factors for Amyotrophic Lateral Sclerosis (ALS). The initiative encourages studies on military service, contact sports, and neuroinflammation, among others. Four funding options are available: enhancing existing evidence, exploring new risk factors, understanding ALS in specific populations, and analyzing biological samples from the Guamanian ALS cluster. This research aims to improve diagnostics, therapeutics, and prevention strategies.
Amyotrophic Lateral Sclerosis (ALS)

PPSEF Student Scholarship (Piedmont)

Communities Foundation of Oklahoma
Private
United States
Unspecified amount

PPSEF Student Scholarship (Piedmont)

Provides a scholarship to a Piedmont graduating senior.

Education - Higher Education Career / College Preparation

Strubhar Family Scholarship (Piedmont)

Communities Foundation of Oklahoma
Private
United States
Unspecified amount

Strubhar Family Scholarship (Piedmont)

Provides a scholarship for a Piedmont high school graduating senior who will study education or law with a GPA of 3.0 and attending a two- or four-year college or university.

Education - Higher Education Career / College Preparation

Sisters of the Sacred Heartland Dr. Allan French Memorial Scholarship

Communities Foundation of Oklahoma
Private
United States
Unspecified amount

Sisters of the Sacred Heartland Dr. Allan French Memorial Scholarship

Provides a scholarship to students in Oklahoma who identify as members of the LGBTQIA2S+ (Lesbian, Gay, Bisexual, Transgender, Queer and/or Questioning, Intersex, Asexual, Two-Spirit, and the countless affirmative ways in which people choose to self-identify) and a minimum GPA of 2.7 or higher.

Education - Higher Education LGBTQIA+ Services

Scott Cornelius Memorial Scholarship (Piedmont)

Communities Foundation of Oklahoma
Private
United States
Unspecified amount

Scott Cornelius Memorial Scholarship (Piedmont)

To honor the memory of Scott Cornelius by supporting students pursuing careers in sales, marketing, insurance or related business fields who demonstrate leadership and integrity.

Education - Higher Education Financial Literacy Career / College Preparation +1 more

Oklahoma Cattlemen's Association Scholarships

Communities Foundation of Oklahoma
Private
United States
Unspecified amount

Oklahoma Cattlemen's Association Scholarships

Provides scholarships to members of the Oklahoma Cattlemen's Association (and their children) who best meet the criteria. In partnership with the Oklahoma Cattlemen's Association.

Academic Scholarship Programs Farms & Farming

Beryl M. Klare Scholarship Endowment

Community Foundation of Wabash County
Private
United States
Unspecified amount

Community Foundation of Wabash County

Since its creation in 1954, the Community Foundation has grown and continually adapted its priorities to meet the ever-changing needs of the community. Through these changes, challenges, and opportunities to grow as both a leader and provider, the Community Foundation has remained true to its mission and commitment to Wabash County citizens.

Our Scholarships

The Community Foundation of Wabash County offers a wide variety of post-secondary education scholarships to traditional, non-traditional, and graduate students. With nearly 70 different scholarship endowments created through the generosity of our donors, many students are eligible to apply.  

Beryl M. Klare Scholarship Endowment

Beryl Klare created a scholarship for residents of the City of Wabash, Indiana, who are accepted into and attend an accredited post-secondary educational institution, including career training and academic degrees. Having no children of her own, she used her will to fulfill her wishes to financially assist students who want to obtain a higher education, including academic degrees and vocational training. When she passed away in 1968, her scholarship became a reality.

Education - Higher Education Vocational & Trade Education

Thing 1∙2∙3 Foundation Grant Program

Thing 123 Foundation
Private
United States
Unspecified amount
The Thing 1∙2∙3 Foundation Grant Program, established in 1999, is dedicated to improving the lives of children. This private foundation, inspired by Dr. Seuss' characters, focuses on providing essential support to organizations that help children. Grants are awarded to U.S. and U.S.-based international entities that align with the foundation's mission. The foundation seeks to empower those on the front lines delivering impactful services, ensuring that children's needs are met effectively.
Child Welfare Services Child Care Services

Custer Scholarship

Community Foundation of Wabash County
Private
United States
Unspecified amount

Community Foundation of Wabash County

Since its creation in 1954, the Community Foundation has grown and continually adapted its priorities to meet the ever-changing needs of the community. Through these changes, challenges, and opportunities to grow as both a leader and provider, the Community Foundation has remained true to its mission and commitment to Wabash County citizens.

Our Scholarships

The Community Foundation of Wabash County offers a wide variety of post-secondary education scholarships to traditional, non-traditional, and graduate students. With nearly 70 different scholarship endowments created through the generosity of our donors, many students are eligible to apply.  

Custer Scholarship

Gene Custer is a lifelong Wabash County resident and farmer and a generous supporter of charitable causes. Gene established the Custer Scholarship Fund to help deserving students pursue post-secondary education. The award is given based on work experience or engagement in extra-curricular school, religious, or community activities; and a character of talent, ambition, initiative, and kindness.

Education - Higher Education Vocational & Trade Education

Dr. Howard and Helen Liebengood Scholarship Fund

Community Foundation of Wabash County
Private
United States
Unspecified amount

Community Foundation of Wabash County

Since its creation in 1954, the Community Foundation has grown and continually adapted its priorities to meet the ever-changing needs of the community. Through these changes, challenges, and opportunities to grow as both a leader and provider, the Community Foundation has remained true to its mission and commitment to Wabash County citizens.

Our Scholarships

The Community Foundation of Wabash County offers a wide variety of post-secondary education scholarships to traditional, non-traditional, and graduate students. With nearly 70 different scholarship endowments created through the generosity of our donors, many students are eligible to apply.  

Dr. Howard and Helen Liebengood Scholarship Fund

The Dr. Howard and Helen Liebengood Scholarship is awarded to students who are residents of Kosciusko County graduating in the top 20% of their high school class. Dr. Liebengood was a veterinarian in Silver Lake and did much to support youth, 4-H programs, and his hometown. This renewable scholarship helps promising students who have financial need.

Education - Higher Education

Paul Thomas Reahard Memorial Scholarship Fund

Community Foundation of Wabash County
Private
United States
Unspecified amount

Community Foundation of Wabash County

Since its creation in 1954, the Community Foundation has grown and continually adapted its priorities to meet the ever-changing needs of the community. Through these changes, challenges, and opportunities to grow as both a leader and provider, the Community Foundation has remained true to its mission and commitment to Wabash County citizens.

Our Scholarships

The Community Foundation of Wabash County offers a wide variety of post-secondary education scholarships to traditional, non-traditional, and graduate students. With nearly 70 different scholarship endowments created through the generosity of our donors, many students are eligible to apply.  

Paul Thomas Reahard Memorial Scholarship Fund

Paul Reahard taught English, creative writing, and theatre arts at Whitko High School where he was the recipient of the prestigious Dekko Foundation Teacher of the Year Award in 1996. His parents created this scholarship to carry on their son’s legacy of bringing out the best in students and awakening the spark of creativity within themselves. Selection will be based on academic performance, and financial need. Community service, work experience, or an indication of interest in and dedication to activities in performing arts, drama, theater, English literature, or creative writing are contributing factors.

Education - Higher Education

Richard L. and Marna L. Hettmansperger Scholarship Endowment

Community Foundation of Wabash County
Private
United States
Unspecified amount

Community Foundation of Wabash County

Since its creation in 1954, the Community Foundation has grown and continually adapted its priorities to meet the ever-changing needs of the community. Through these changes, challenges, and opportunities to grow as both a leader and provider, the Community Foundation has remained true to its mission and commitment to Wabash County citizens.

Our Scholarships

The Community Foundation of Wabash County offers a wide variety of post-secondary education scholarships to traditional, non-traditional, and graduate students. With nearly 70 different scholarship endowments created through the generosity of our donors, many students are eligible to apply.  

Richard L. and Marna L. Hettmansperger Scholarship Endowment

When their Methodist Church building closed, the Hettmanspergers put the money from the sale of the church to work as a scholarship for graduate students who want to prepare for missions, ministry, or one of the helping professions, such as social work, counseling, nursing, public health, and education.

Education - Higher Education

Wabash Baking Powder Company Scholarship

Community Foundation of Wabash County
Private
United States
Unspecified amount

Community Foundation of Wabash County

Since its creation in 1954, the Community Foundation has grown and continually adapted its priorities to meet the ever-changing needs of the community. Through these changes, challenges, and opportunities to grow as both a leader and provider, the Community Foundation has remained true to its mission and commitment to Wabash County citizens.

Our Scholarships

The Community Foundation of Wabash County offers a wide variety of post-secondary education scholarships to traditional, non-traditional, and graduate students. With nearly 70 different scholarship endowments created through the generosity of our donors, many students are eligible to apply.  

Wabash Baking Powder Company Scholarship

The Wabash Baking Powder Company Scholarship was established to preserve the company legacy as a flourishing enterprise and was once the largest private brand baking powder factory in the world, producing not only baking powder, but a variety of flavoring extracts, gelatin extracts, powdered skim milk, and cocoa for over 200 companies. The Wabash Baking Powder Company was located on the northwest corner of South Wabash Street and Water Street. The building was directly on the Wabash & Erie Canal and was believed to have originally been a warehouse for the import and export of Canal goods and merchandise.

Engineering Agriculture Business Education +2 more

Great American Main Street Awards

National Main Street Center Inc.
Private
United States
Unspecified amount

National Main Street Center Inc.

Main Street America (MSA) leads an inclusive, impact-driven movement dedicated to reenergizing and strengthening older and historic downtowns and neighborhood commercial districts through place-based economic development and community preservation. We work in collaboration with thousands of local partners and grassroots leaders across the nation who share our commitment to advancing shared prosperity, creating resilient economies, and improving quality of life.

Main Street America was founded in 1980 as the National Main Street Center®, a program of the National Trust for Historic Preservation. Over the past 40 years the MSA network has helped to generate over $115.27 billion in local reinvestment, rehab 345,801 buildings, create 815,894 new jobs, and start 181,647 new businesses in over 2,000 communities. 

Great American Main Street Awards

Main Street America celebrates communities whose successes serve as a model for comprehensive, preservation-based revitalization efforts in their historic downtowns and commercial corridor districts with the Great American Main Street Awards (GAMSA).

Winners represent the diversity of communities in the Main Street America network — small towns, mid-sized communities, and urban commercial districts from every region in the country — and demonstrate the power of the Main Street Approach™. Since the inception of the Great American Main Street Awards in 1995, 118 Main Street programs have been honored.

Selection Criteria: Semifinalists and winners are selected from a nationwide pool of applicants by a jury of Main Street professionals and leaders in the fields of community and economic development and historic preservation. Criteria for winning GAMSA include: strength of the Main Street program in spurring community transformation, commitment to historic preservation, innovative programming, implementation of cross-sector partnerships, community outreach and stakeholder engagement, and ensuring their downtown districts are for everyone. 

Accolades & Ceremony: Semifinalists are promoted through Main Street America’s digital channels and receive media relations support. Winners also receive a short documentary film, a plaque, communications and media relations support, prominent placement on the Main Street America website for two years, and recognition at the 2027 Main Street Now Conference in Detroit, Michigan.

Economic Services & Development Community Development & Revitalization Historic Preservation

Buffalo County Grants for Nonprofits Highlights

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Read more about each grant below or start your 14-day free trial to see all Buffalo County grants recommended for your specific programs in South Dakota.

Last updated: November 2, 2026. Next update: December 6, 2026.

Grant Insights : Grant Funding Trends in South Dakota

Average Grant Size

What's the typical amount funded for South Dakota?

Grants are most commonly $110,621.

$110,621

Total Number of Grants

What's the total number of grants in Buffalo County Grants for Nonprofits year over year?

In 2024, funders in South Dakota awarded a total of 6,460 grants.

2022 6,268

2023 6,140

2024 6,460

Top Grant Focus Areas

Among all the Buffalo County Grants for Nonprofits given out in South Dakota, the most popular focus areas that receive funding are Education, Human Services, and Philanthropy, Voluntarism & Grantmaking Foundations.

1. Education

2. Human Services

3. Philanthropy, Voluntarism & Grantmaking Foundations

Funding Over Time

How is funding for Buffalo County Grants for Nonprofits changing over time?

Funding has increased by 17.48%.

2022 $638,830,994

2023 $606,495,212
-5.06%

2024 $712,509,384
17.48%

South Dakota Counties That Receive the Most Funding

How does grant funding vary by county?

Minnehaha County, Lake County, and Pennington County receive the most funding.

County Total Grant Funding in 2024
Minnehaha County $176,653,145
Lake County $117,647,066
Pennington County $90,630,616
Brookings County $75,457,854
Todd County $56,559,538