Best Large Grants for Nonprofit Organizations in California

The Awards for Advancing Minority Mental Health, established by the American Psychiatric Association Foundation in 2003, aim to honor community organizations that promote mental health awareness in underserved minority communities. These awards recognize efforts to improve access to quality mental health services, enhance treatment quality, and address cultural barriers. Organizations must have been operational for at least two years and demonstrate innovative approaches to mental health challenges.

The Great Lakes Safety Training Center Scholarship, established by local contractors and businesses, aims to support residents of Gratiot or Saginaw County pursuing careers in trades or construction with a focus on safety. This scholarship is available to individuals enrolled in degree or certification programs at accredited institutions in Michigan, emphasizing the importance of safety in skilled trades. With awards typically ranging from $500 to $4,000, this initiative addresses the growing demand for skilled workers in the community.

Community Foundation of Northwest Mississippi

The Community Foundation of Northwest Mississippi manages 314 donor-established funds and has disbursed over $48 million to support more than 1,000 charitable organizations and activities recommended by its donors, as well as charitable programs established by the foundation. Established in 2002 with a generous grant from the Maddox Foundation, the Community Foundation is an independent 501(c)3 charitable organization. The Foundation serves Bolivar, Coahoma, DeSoto, Leflore, Marshall, Panola, Quitman, Sunflower, Tallahatchie, Tate, Tunica and Yalobusha counties. 

The Reese and Joelle Norris Service through Music Scholarship

The Community Foundation, CoroRio, and MidSouth Music Institute is pleased to offer a $500 college scholarship: The Reese and Joelle Norris Service through Music Scholarship. We are grateful to Reese and Joelle Norris for more than ten years of service to CoroRio and the MidSouth Music Institute. Together, they have nearly 50 years of teaching thousands of all ages throughout the MidSouth and across the country.

Starting in the Spring of 2024, the scholarship will be awarded each year to a student who is currently involved in CoroRio, plans to pursue a career related to music, and has demonstrated a passion for serving others through music, like Reese and Joelle. 

The Undergraduate Development Program Advisor Travel Award, hosted by the Society of Toxicology, enables faculty advisors to attend the Undergraduate Development Program from March 21-23, 2026. This initiative aims to familiarize advisors with toxicology and encourage them to guide students toward careers in biomedical sciences. Recipients of the award will participate in educational sessions, networking opportunities, and receive support for travel-related expenses, fostering diversity and innovation within the field.

The Guadalupe “Lupe” Gomez Memorial Scholarship, established by Lupe's family after her passing in 2009, honors her legacy of dedication and service in education and the community. This scholarship supports students from Saginaw County who demonstrate hard work and self-motivation, particularly those pursuing Career and Technical Education (CTE) or other degrees. With awards ranging from $500 to $4,000, it aims to empower the next generation of skilled workers in various trades.

The Hebert Memorial Scholarship, established by Jacquelyn and Donald Hebert, aims to support Saginaw County residents pursuing higher education. With a minimum GPA requirement of 3.0, this scholarship is available to graduating high school seniors and current college students enrolled full-time. The Heberts, who valued education and community service, created this fund to help students achieve their academic goals, reflecting their commitment to enhancing the lives of local youth.

The Pajaro Valley Community Health Trust Grant aims to foster health equity and wellness in the Pajaro Valley. With grants of $15,000 available, the Trust encourages organizations to collaborate and align with strategic focus areas such as building health equity and increasing wellness. The grant prioritizes impactful initiatives and supports nonprofits, school-based health programs, and those with a fiscal sponsor. This initiative reflects the Trust's commitment to enhancing quality of life for all residents.

About Us

The Community Foundation of Dickinson County, Inc. was established in 1999 by a group of civic-minded individuals who cherished their community and wanted to ensure future generations experience the same quality of living they had received in Dickinson County. These visionaries secured the future of the Foundation by establishing an Endowed Founder’s Fund.

Woodrow and Esther Tyrell Scholarship - (2 or more) $20,000

The Woodrow and Esther Tyrell Scholarship honors the lives and legacy of Benjamin Woodrow Tyrell and Esther Tyrell, whose commitment to hard work, service, and education continues to benefit students in Dickinson County. Born in Talmage, Kansas, Woodrow Tyrell served in World War II before returning home to work at the Abilene Flour Mill for 33 years. Esther Tyrell, originally from Longford, Kansas, was a longtime educator in Dickinson County. Married in 1952, the Tyrells shared a strong belief in the importance of education. Through their generous endowment at the Community Foundation of Dickinson County, their legacy continues to support students and foster brighter futures through educational opportunity.

About Us

The Community Foundation of Dickinson County, Inc. was established in 1999 by a group of civic-minded individuals who cherished their community and wanted to ensure future generations experience the same quality of living they had received in Dickinson County. These visionaries secured the future of the Foundation by establishing an Endowed Founder’s Fund.  

Woodrow and Esther Tyrell Technical Scholarship - (Up to 5) $10,000

The Woodrow and Esther Tyrell Technical Scholarship honors the legacy of Benjamin Woodrow Tyrell and Esther Tyrell, whose lives reflected a strong commitment to hard work, service, and education. Born in Talmage, Kansas, Woodrow Tyrell served in World War II before returning to Dickinson County, where he worked for 33 years at the Abilene Flour Mill. Esther Tyrell, originally from Longford, Kansas, dedicated her career to education in Dickinson County. Married in 1952, the Tyrells believed deeply in the value of education and skills-based training. 

The Numotion Foundation Grants aim to enhance the lives of individuals with mobility disabilities by supporting IRS-designated 501(c)(3) nonprofit organizations. By fostering partnerships with various charities, including national and local organizations, the foundation raises awareness and funds for necessary research and support services. Contributions are made for each new wheelchair sold, ensuring a coordinated approach to charitable giving while prioritizing programs that specifically assist those with mobility-related challenges.

The St. Baldrick's Foundation Scholar (Career Development) Award supports early-career researchers dedicated to childhood cancer research. This three-year award, which can be extended for two additional years based on progress, provides up to $110,000 per year. Founded in 2000, the foundation has mobilized volunteers worldwide to raise funds through head-shaving events and various activities, all aimed at finding cures and improving survivors' lives.

The St. Baldrick’s Foundation Summer Fellowship Award provides funding for undergraduate, graduate, or medical students to gain hands-on experience in pediatric oncology. With a stipend of $5,000 awarded to the mentor's institution, this fellowship supports the next generation of researchers dedicated to finding cures for childhood cancers. Since its inception, the foundation has mobilized volunteers through various fundraising events, fostering a community committed to transforming lives and advancing cancer research.

Implementing Germline and Somatic Testing for Precision Medicine in Community-Based Prostate Cancer Care 

The intent of this Request for Proposal (RFP) is to invite organizations to submit applications to host a 2.5-to-3 hour medical education program at or nearby the organization, to be led by 1-2 Visiting Professors (VPs) with expertise matched to the organization’s unmet educational and pragmatic needs related to integrating and acting on germline and somatic (tumor and/or ctDNA) testing for patients with prostate cancer. Following the education program, organizations will implement their action plan to incorporate, increase, or improve the use of guideline-concordant germline and somatic testing to improve prostate cancer patient care.

The total budget for the RFP is $250,000 USD, with plans to support 5-7 organizations. Individual project budgets should not exceed $50,000 USD.

We are Revolutionaries

Who We Are

We are Revolutionaries -passionate in our singular pursuit of discovering, developing and delivering innovative targeted therapies for patients living with RAS-addicted cancer. At Revolution Medicines, we believe in challenging the status quo to find new therapeutic approaches to some of the toughest cancers. With our first wave of investigational RAS(ON) inhibitors, we are pioneering a new way of targeting the RAS cancer drivers of disease, and we have the potential to change the treatment paradigm in these cancers where there is a significant unmet medical need.

Our mission is to revolutionize treatment for patients with RAS-addicted cancers through the discovery, development and delivery of innovative, targeted medicines.

Research, Grants & Support

At Revolution Medicines, we understand the importance of extending our support of scientific advancement beyond the research we conduct and the medicines we provide.

We support activities that make meaningful information and resources available to the broader medical and scientific communities to help advance science, increase understanding of certain diseases, and enhance patient care.

Charitable Donations

Funding for programs that deliver disease awareness, treatment education, or other healthcare information intended to improve patient understanding and empowerment.

The Ken and Eileen Gross Memorial Scholarship, established by friends of the couple, supports Saginaw County high school seniors pursuing a teaching degree. With a focus on fostering education, this scholarship honors Ken, a dedicated educator, and Eileen, a successful property manager. Eligible students must demonstrate a minimum 3.0 GPA and financial need, ensuring that those committed to teaching can pursue their aspirations. Awards typically range from $500 to $4,000, empowering the next generation of educators.

The Ruth Danley and William Enoch Moore Charitable Fund Grant is a private foundation based in Pittsburgh, established in 1992. It focuses on philanthropy, specifically supporting K-12 education for Native American children living on reservations. The foundation directs its grants primarily to regions preferred by donors, including several states in the Northeast and Midwest, aiming to improve educational opportunities and foster community development in underserved populations.

Albert Smith Conservation Scholarship

Albert A. Smith was born in Omer, Mich., in 1913. He began his education in a one room schoolhouse near Omer and successfully completed his first three grades in the first year of school. Upon graduation from Flint Northern High School at age 15, he went on to receive an undergraduate degree from the University of Michigan and thereafter a law degree in 1939. In the mid-1950s, he opened a law office in Saginaw that later became the law firm of Smith Bovill, P.C.

Mr. Smith’s love of the law was matched by his interest in the outdoors, and in particular his beloved Ruffed Grouse. He used his rolling farm and woods to entertain his friends, clients and courtroom adversaries. He was a consummate host to anyone who shared his love for the hunt.

Al was generous with his time and resources. He supported and served on the boards of his favorite charities and civic groups, including the Salvation Army, the Ruffed Grouse Society where he served as national president, the Samaritan Center and First Congregational Church. In 1976, he was recognized for his outstanding conservation work when he received the Wildlife Conservationist of the Year Award from the Michigan United Conservation Clubs.

The Andrew Burgin Charitable Trust Grant supports organizations that are exempt under Section 501(c)(3) and focuses on charitable, educational, religious, and scientific purposes. With grant sizes ranging from $5,000 to $20,000 and an annual budget of approximately $55,000, the trust primarily serves Alabama organizations. Applications are accepted year-round, but must meet specific deadlines for review. This grant offers opportunities across diverse areas such as arts, education, health, and human services.

Louis R. & Helen E. Schwartz FFA Agricultural Scholarship

The Louis R. and Helen E. Schwartz FFA Agricultural Scholarship was established to help prepare Saginaw County students for a future in agriculture or an agriculture-related field. Both Lou and Helen Schwartz were raised on farms in Iowa, so they knew from first-hand experience that farming can be a difficult business. They moved to Frankenmuth when Lou opened area S&H Stores in 1962. The stores were sold to Quality Farm and Fleet in 1982.

Scholarships are awarded to students from Saginaw County, Michigan; Lyon County, Minnesota and Muscatine County, Iowa.

The NIA Expanding Research in AD/ADRD Summer Research Education Program supports the recruitment of early-stage investigators and aims to provide hands-on research experiences in Alzheimer's Disease and related dementias. Targeting high school students, undergraduates, and science teachers, the program enhances STEM education through authentic research opportunities and educational activities. By fostering early exposure to research, it aims to stimulate interest in AD/ADRD careers and address workforce shortages in this critical field.

The Tommy Aaron/Charlie Aaron Foundation Scholarship, managed by the North Georgia Community Foundation, supports graduating seniors from Hall County or Gainesville City public schools and Lakeview Academy. This $10,000 scholarship, distributed over four years, promotes academic achievement and integrity through golf. Eligible applicants must have a minimum GPA of 2.5, demonstrate financial need, and exhibit strong character traits. This initiative aims to empower local students to pursue higher education while honoring the values of sportsmanship and respect.

The Eviction Protection Grant Program (EPGP) aims to support low-income tenants facing eviction by offering competitive awards to around 16 nonprofit organizations and government entities. These grants will fund no-cost legal assistance, covering pretrial, trial, post-trial, and alternative dispute resolution services. The initiative, backed by the Department of Housing and Urban Development, is designed to ensure that vulnerable tenants have access to essential legal resources, ultimately reducing eviction rates and promoting housing stability.

Community Foundation of Henderson County

Community Foundation of Henderson County was incorporated in 1982 by a group of fourteen dedicated and compassionate local leaders with the immediate need to manage two funds - the William C. Armstrong Scholarship Fund and the Charlie Renfrow Scholarship Fund, in addition to providing a permanent vehicle for citizens to give back to their community.

Our Mission is to help people who care make lasting contributions to causes that matter. The Community Foundation of Henderson County is a highly visible, philanthropic leader directed by an engaged and committed board, staffed by qualified employees, empowering donors at all levels to invest in professionally managed charitable funds that address community needs.

Fredrick E. and Mary Meyer Scholarship

Applicant must demonstrate financial need and be pursuing a degree to become a registered nurse (RN). The scholarship is renewable. Recipients must maintain a 3.0 average in order to have their scholarship renewed.

The Donald & Janice Svehla Family Endowed Scholarship, established in 2022 by their sons, supports students from Lincoln Northeast High School pursuing higher education. This initiative, backed by the Lincoln Community Foundation, honors Donald and Janice's dedication to education and community involvement. In 2025, the scholarship contributed to over $606,000 awarded to 299 recipients. It emphasizes the importance of academic excellence alongside financial need, continuing a legacy of support for local students.

The Next Generation Graduate Scholarship, established by the Architects Foundation, supports aspiring architects from diverse backgrounds. With an award of up to $20,000 over five years, it aims to enhance education accessibility in architecture. This initiative honors Whitney Young Jr.'s call for a more responsible profession, inviting students from technical schools, community colleges, and non-NAAB programs to apply. The scholarship not only aids in educational pursuits but also fosters a network of future leaders in architecture.

The Next Generation Undergraduate Scholarship, established by the Architects Foundation, aims to support diverse students pursuing architecture degrees. With a total award of up to $20,000, the scholarship is available to US citizens or permanent residents who are seniors in high school or second-year college students enrolled in NAAB-accredited programs. This initiative reflects a commitment to fostering inclusivity and excellence in the architectural profession, empowering future leaders to shape the built environment.

The AOA/AOSA Opportunities in Optometry Grant program aims to promote inclusion within the optometric profession. This program offers $1,500 grants to under-represented minority students who are applying to optometry school. Eligible candidates include U.S. citizens, permanent residents, or DACA recipients who meet specific academic criteria. The initiative seeks to enhance diversity in the field and expand access to primary eye care, supporting the next generation of optometrists.