Best Large Grants for Nonprofit Organizations in California

The INCLUDE Project aims to enhance the health and quality of life for individuals with Down syndrome by generating comprehensive genomic and multi-omics data. This initiative encourages applicants to submit samples to NIH-supported resources, facilitating the exploration of molecular mechanisms related to health conditions associated with Down syndrome. The data will be shared via the INCLUDE Data Hub, promoting collaboration within the research community, though no direct funding is available to applicants.

The Coordinating Agricultural Development & Innovation (CADI) initiative fosters trade growth in Eastern Europe, the South Caucasus, and Central Asia by removing barriers to U.S. agricultural exports. Funded by the USDA's Foreign Agricultural Service, CADI aims to inject over $622 million into the U.S. economy while preventing potential losses exceeding $50 billion. The awardee will conduct essential research and provide actionable recommendations to support U.S. farmers and enhance trade relationships, ensuring a prosperous agricultural sector.

The DoW Bone Marrow Failure Idea Development Award supports innovative, high-impact research aimed at understanding and curing bone marrow failure diseases. This grant is available to both Established Investigators and Early-Career Investigators, with no preliminary data required for applications. Reviewers assess proposals based on specific criteria tailored to the investigator's career stage. The focus is on achieving interpretable results that contribute significantly to the field.

The Gladys Lasky Endowment Fund Ballet Scholarship, established in 2000 by the Community Foundation of Central Georgia, aims to support ballet students in Georgia by providing funding for classical ballet instruction or summer intensives. Each year, one scholarship is awarded to a deserving student, prioritizing those with financial need and ties to Central Georgia. Recipients are selected based on recommendations, potential for success, and years of formal dance training.

The AABCF Research Grants, offered by the American Association of Birth Centers Foundation, provide funding up to $5,000 for research projects focused on the birth center model of care. Open to individuals and organizations, these grants aim to enhance knowledge and practices in maternity and women's health care. Projects must demonstrate a clear plan and ability to complete the research on schedule, ensuring impactful contributions to the field.

The Greater Tindall Neighborhood Scholarship Fund, established by the Community Foundation of Central Georgia, aims to support residents of Tindall Heights pursuing post-secondary education. It offers $2,000 per recipient, renewable for up to four years. Eligible applicants must demonstrate financial need, maintain a minimum 2.0 GPA, and enroll full-time at an accredited institution. The scholarship fosters educational growth and community development, ensuring that residents have the necessary resources to succeed in their academic endeavors.

Ocean State Media Scholarship

The scholarship offers awards to residents of Ocean State Media’s demographic market area who demonstrate promise of a successful career in the fields of journalism and/or media.

Scholarship Award Details

Established by Rhode Island PBS in 2017, the Ocean State Media Scholarship offers awards to residents of the station’s demographic market area who demonstrate promise of a successful career in the fields of journalism and/or media. Awards of up to $15,000 will be awarded annually and are renewable for an additional three years.

The Edna Haberle Visual Arts Scholarship, administered by the East Texas Communities Foundation, supports graduating seniors from Cherokee County and surrounding East Texas counties who plan to pursue a major in visual arts. This scholarship emphasizes the importance of education in achieving dreams and considers financial need, requiring FAFSA submission. Applicants must demonstrate artistic potential and commitment to their field of study to be eligible for this one-year support opportunity.

The Ruth D. Frick Ames Scholarship, established by Robert Ames to honor his wife, supports students pursuing a nursing degree. Managed by the South Dakota Community Foundation, this scholarship aims to ease the financial burden for those aged 18-32 with a GPA of 2.9 or higher. Applicants should demonstrate financial need, strong academic performance, and community involvement. This initiative reflects Ruth's legacy of compassion, service, and commitment to helping others in the nursing field.

The Hilda M. Hill Memorial Scholarship is offered by the Four County Community Foundation to support high school seniors and recent graduates from Capac, Almont, and Imlay City. Eligible students planning to pursue vocational or technical programs may apply, with financial need considered. Recipients will be recognized at the Foundation Scholarship Celebration in May, as well as during high school awards ceremonies. Students can receive up to two awards, promoting continued educational advancement in skilled trades.

The AICEF Cultural Grant aims to enhance cultural ties between the United States and Indonesia by funding projects in the performing, visual, and literary arts. With grants ranging from $1,000 to $5,000, the foundation seeks to support distinguished individuals and groups whose work is accessible to the public and fosters goodwill between the two nations. This initiative not only promotes artistic excellence but also bridges cultural exchanges for a diverse audience.

The Frances Cowan Gibson Fine Arts Scholarship, offered by the East Texas Communities Foundation, supports graduating seniors and current college students pursuing visual arts. This scholarship emphasizes the importance of education in achieving artistic ambitions. Applicants must be from Smith County and are not required to demonstrate financial need. It rewards students dedicated to their artistic studies, allowing them to continue their education in visual arts at any college in the United States.

The Kathy’s Kids Scholarship, established in honor of Kathy Smith, provides educational support for young women in the Longview area facing challenges. Administered by the East Texas Communities Foundation, this scholarship aims to empower graduating seniors to pursue their educational goals. With a focus on financial need, applicants must be from participating high schools and demonstrate resilience in overcoming adversity. Scholarships of $1,500 are available and may renew annually, emphasizing the foundation's commitment to fostering educational opportunities.

The Pittsburgh Foundation

Established in 1945, The Pittsburgh Foundation is one of the nation’s oldest community foundations and as of 2022 is the 18th largest of more than 750 similar foundations across the United States.

As a community foundation, its resources comprise endowment funds established by individuals, businesses and organizations with a passion for charitable giving and fulfilling the Foundation’s mission of improving quality of life for all in the region. The Foundation currently manages about 2,500 individual donor funds and, together with its supporting organizations and its affiliate, The Community Foundation of Westmoreland County, has assets of $1.386 billion (2022). Grantmaking benefits a broad spectrum of basic needs and development opportunities within Pittsburgh and beyond.

Scholarships

The Pittsburgh Foundation and The Community Foundation of Westmoreland County provide scholarship opportunities for local students to pursue their educational goals. Scholarships are available for graduating high school seniors, undergraduates, graduate, medical and professional school students who are attending community colleges, four-year universities and career/technical schools.

Elaine Sirkin Forbes Scholarship Fund

The Elaine Sirkin Forbes Scholarship Fund was created at The Pittsburgh Foundation to provide scholarships for high school seniors graduating from Allegheny County Schools who wish to major in visual, performance or media art.

Award Type: Single-Year Award

The DoW Bone Marrow Failure Investigator-Initiated Research Award supports innovative research aimed at advancing the understanding and treatment of bone marrow failure. This funding opportunity encourages applications for translational and clinical studies, requiring preliminary data to strengthen proposals. Unique features include the ability for a partnering Principal Investigator to contribute to the research, thereby fostering collaboration while maintaining a focus on significant advancements in patient care.

The Leukemia Exploration and Prevention Grant Program (LEAP) aims to advance cancer interception and prevention for patients with RUNX1 familial platelet disorder (RUNX1-FPD). This program supports interdisciplinary research teams investigating the mechanisms of leukemogenesis and innovative treatment strategies. With funding of up to $430,000 per year, LEAP encourages projects focused on both understanding clonal evolution and developing novel therapeutic approaches. The initiative seeks to bridge critical knowledge gaps and provide urgent interventions for high-risk populations.

The Leukemia Exploration and Prevention Grant Program (LEAP) aims to advance cancer interception and prevention strategies for patients with RUNX1 familial platelet disorder. This initiative, supported by the American Cancer Society, focuses on understanding the mechanisms behind leukemia development and fostering innovative research leading to effective treatment options. Grants of up to $215,000 per year for four years are available, emphasizing the urgent need for targeted therapies in high-risk populations.

The John Stashonsky Memorial Scholarship, offered by the Muskingum County Community Foundation, supports graduating seniors from John Glenn High School, Cambridge High School, or Mid-East Career and Technology Center (Zanesville Campus) who are pursuing higher education. Applicants are required to maintain a minimum GPA of 3.0. This scholarship aims to enhance educational opportunities and improve the quality of life in Muskingum County through philanthropy.

The FY26 Duchenne Muscular Dystrophy Research Program's Idea Development Award promotes innovative, high-risk research aimed at advancing treatment for Duchenne muscular dystrophy (DMD). It encourages projects with a strong scientific basis and feasibility, focusing on therapies that work across all ages, including infants and nonambulatory patients. Eligible applicants include experienced and transitioning investigators, fostering diverse expertise to enhance DMD research and improve patient outcomes.

The grant mechanism will focus on furthering the development of strategies towards improving the outcomes of Small Cell Lung Cancer (SCLC) patients through patient advocacy. Work supported through this mechanism will address important areas of need across the entire care continuum and have the immediate potential to increase research efforts, quality of life and survivorship. The overarching theme of the proposals should be centered around using patient advocacy as a tool to develop strategies toward improving outcomes for patients with SCLC. We will encourage applications on a wide variety of topics related to SCLC, including but not limited to the following:

• Patient-Centric Care Models
  • Develop and implement care models that prioritize patient needs and preferences, integrating innovative approaches from diagnosis through survivorship
• Advanced Screening and Diagnostic Technologies
  • Create comprehensive survivorship care plans addressing long-term healthcare needs, focusing on follow-up care, monitoring for recurrence, and managing chronic side effects

• Access and Equity
  • Investigate barriers to accessing quality care, clinical trials, screening and biomarker testing for SCLC patients and purpose solutions to ensure equitable healthcare delivery for diverse populations

• Technology Integration
  • Explore the use of digital health tools and technologies to facilitate better patient-provider interactions, personalized care, and continuous monitoring during the care continuum
• Patient Feedback Mechanisms
  • Establish robust feedback systems to gather patient insights and experiences and use this data to inform continuous improvements in care delivery, diagnostic technologies, treatment approaches, clinical protocols and accessible repositories to facilitate broad research collaboration

The 2026 Strategies Using Patient Advocacy to Improve Outcomes in Small Cell Lung Cancer will grant a minimum of one award of $250,000 for a period two years ($125,000 per year).

The National Fish Passage Program (NFPP) offers technical and financial support to restore aquatic connectivity for fish and other organisms. By improving infrastructure like culverts and bridges, the program enhances fish populations and ecosystem resilience, providing quality fishing experiences. Managed by the US Fish and Wildlife Service, NFPP collaborates with partners to implement strategic projects that align with conservation goals, ensuring biological diversity and effective use of scientific principles in project planning.

The National Institute of Allergy and Infectious Diseases (NIAID) is advancing research on immune tolerance through its Collaborative Network. This program aims to clarify the mechanisms of immune tolerance and develop interventions for related diseases, including transplant rejection and autoimmune disorders. Key objectives include conducting clinical trials on tolerogenic strategies and refining immune assays. This initiative is supported by regulations under the Public Health Service Act, ensuring a structured approach to improving patient outcomes.

American College Of Sports Medicine Foundation Inc

ACSM is the largest sports medicine and exercise science organization in the world, with nearly 50,000 international, national and regional members and certified fitness professionals.

Our Mission: To educate and empower professionals to advance the science and practice of health and human performance.

GSSI Pathways in Sports Science Award | Graduate Student Research & Mentorship Award

GSSI celebrates the passion, resilience, and academic excellence of first-generation college students pursuing graduate degrees in exercise physiology, sports science, kinesiology, and/or sports nutrition. Designed to empower emerging leaders in the field, the award recognizes individuals who are breaking new ground, not only in their families but in the science of human performance.

In addition to research funding, to help promote professional development, award winners will receive one year of 1:1 mentorship from a GSSI scientist. Award winners will also receive complementary registration to ACSM’s 2027 Annual Meeting in Indianapolis, IN.

ACSM requires award winners to:   

• Submit official transcripts if selected as an award winner, 
• Attend the 2027 ACSM Annual Meeting in Indianapolis, IN. 
• Present funded research at a future ACSM Annual Meeting, and   
• Send ACSM a copy of any publications or presentations related to the funded research. 

The Lawrence A. Taylor Research Fund in Petrology and Geochemistry offers financial support to two PhD students demonstrating outstanding research in Petrology and/or Geochemistry. Funded by Dong-Hwa Shin (Dawn) Taylor, this grant aims to alleviate some financial burdens associated with their doctoral studies, fostering excellence in these critical fields. Eligible candidates must be AGU student members currently enrolled in relevant doctoral programs and engaged in applicable research.

The Joseph Nurre Football Memorial Scholarship, offered by the Elk Grove Regional Scholarship Foundation, supports students from the Elk Grove Unified School District who have played football. This scholarship prioritizes full-time students with a minimum GPA of 2.5 and requires participation in school and community activities. An essay describing the importance of football is necessary. If no eligible football players apply, the scholarship may be awarded to a foster youth from the area.

The AMD Resident Research Grant aims to foster innovative research projects related to migraine, encouraging residents to explore diverse topics that are scientifically sound. Applicants, who must be enrolled in accredited training programs, can collaborate with preceptor investigators and receive support from their institutions. The grant is open to all residents without country restrictions, promoting advancements in migraine understanding and treatment.