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Best Large Grants for Nonprofit Organizations in California

Find the perfect Large Grants for Nonprofit Organizations in California on Instrumentl. 11,000+ Large Grants for Nonprofit Organizations in California in the United States.

11,000+

Available grants

$3.61B

Total funding

$5K

Median grant

11,000+ grants
$3.61B total
$5K median

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Jack Beaty Educational Scholarship Foundation Grant

Jack Beaty Educational Scholarship Foundation
Association/Society
United States
Unspecified amount

Jack Beaty Educational Scholarship Foundation Grant

Jack Beaty was a pillar of the community he lived in and loved. He was a successful businessman from an early age having founded two companies. One company supplied food to retail stores throughout New Mexico, where Jack became friends with all his customers and fell in love with the state. He founded an oil and gas company in Farmington, New Mexico as well.

Jack eventually became involved in politics in New Mexico where he served as the Bernalillo County Democratic Chairman and the New Mexico State Democratic Chairman. During the 1960 Presidential campaign, Jack became friends with John F. Kennedy and Robert Kennedy. Jack served as the Western States coordinator for the Kennedy campaign. After the 1960 election, Jack sold his food supply business and moved to Washington, D.C. Jack served in both the Kennedy and Johnson Administrations. Following this service, Jack formed the public relations firm Jack Beaty and Associates in Washington, D.C.

While in Washington, D.C., Jack met and married Rose Marie Beaty Martinez, the personal assistant to Senator Joseph M. Montoya, the United States Senator from Mexico. Jack and Rose Marie retired to New Mexico in 1979 where Jack devoted his time to managing Western Minerals and Oil. Jack desired that upon his and Rose Marie’s death that his estate be used to assist and provide access to education to less fortunate students in New Mexico.

In his estate plan, Jack desired that the Jack Beaty Educational Scholarship Foundation be established to carry out his charitable goal of assisting students to obtain a secondary education.

Education - Higher Education Education - High School Vocational & Trade Education

Dunkirk Community Funds: Marilee & Gayle Gaunt Scholarship

Portland Foundation
Private
United States
Unspecified amount
The Dunkirk Community Funds: Marilee & Gayle Gaunt Scholarship, established in 2007 by The Dunkirk Foundation, honors the memory of Betty L. Gaunt's daughters, Marilee and Gayle, who tragically passed away in 1966. This scholarship aims to support residents of Dunkirk, IN, or those living within two miles of its boundary, by providing financial assistance for educational and vocational training at post-secondary institutions.
Education - Higher Education Vocational & Trade Education Career / College Preparation

Herbert K. and Isabel C. Liebich Scholarships

The Community Foundation for the Greater Capital Region
Private
United States
Unspecified amount

About Us

Our mission is to strengthen our community through philanthropy.

We do this in collaboration with donors and community partners who share our vision for community transformation through stewardship of charitable endowments, superior donor services, effective grantmaking, and leadership to address community needs.

The Community Foundation is governed by a Board of Directors and staffed by a team of local experts, representing diverse backgrounds, interests, and professional expertise. Foundation staff members work closely with donors, grantees, community leaders, government agencies, and businesses to ensure the Community Foundation effectively meets community needs.

Who We Are

Empowering generous people with meaningful giving opportunities

Since 1968, The Community Foundation for the Greater Capital Region (CFGCR) has been dedicated to improving the quality of life in the Greater Capital Region. We work with — and for — all our neighbors across the community because together, we are stronger.

Herbert K. and Isabel C. Liebich Scholarships

Established to honor the founders of Albany Frosted Foods, one of the original companies to form Sysco Corporation, by awarding a scholarship each year to the children of employees or retirees of Sysco Foods of New York, Inc. 

Education - Higher Education Education - High School Academic Scholarship Programs

Small Business Transition Grant for New Entrepreneurs (Parent R41/R42 Clinical Trial Optional)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
United States
Unspecified amount
The Small Business Transition Grant for New Entrepreneurs, funded by the NIH, aims to support early-career scientists as they transition into entrepreneurship. This program invites eligible small business concerns to apply for STTR Phase I and Fast-Track grant applications, which include funding for research and development, as well as essential entrepreneurial training and mentorship. It is designed for first-time Principal Investigators, emphasizing the importance of industry mentorship in project development.
Entrepreneurship Business Development

Small Business Transition Grant for New Entrepreneurs (Parent R43/R44 Clinical Trial Optional)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
United States
Unspecified amount
The Small Business Transition Grant for New Entrepreneurs aims to support early-career scientists transitioning into entrepreneurship. Funded by the NIH and CDC, this initiative encourages small business concerns to apply for SBIR Phase I and Fast-Track grants. Key components include research funding, entrepreneurial training, and mentorship. Potential applicants are urged to prepare their projects and identify mentors, ensuring the inclusion of experienced personnel committed to the project. This opportunity is tailored for first-time Principal Investigators.
Entrepreneurship Business Development

African-American Community Foundation - Major John F. Harris, Jr., Memorial Scholarship

The Dayton Foundation
Private
United States
Up to US $1,000
The African-American Community Foundation - Major John F. Harris, Jr., Memorial Scholarship aims to support JROTC graduates from Dayton Public Schools in pursuing higher education. Established by The Dayton Foundation, it honors Major John Harris, Jr., a dedicated instructor who inspired students to achieve independence. Eligible applicants must demonstrate leadership and be accepted into accredited educational institutions. This scholarship reflects the Foundation's commitment to enhancing educational opportunities and empowering youth in the Greater Dayton area.
Education - Higher Education Vocational & Trade Education Career / College Preparation

African-American Community Foundation - Wahid Abdullah Memorial Scholarship

The Dayton Foundation
Private
United States
Up to US $500
The African-American Community Foundation - Wahid Abdullah Memorial Scholarship, established in 1997 by Jim Bucher, honors the memory of Wahid Abdullah, a promising young scholar whose life was tragically cut short. This scholarship aims to support Montgomery County students pursuing higher education at accredited institutions. The Dayton Foundation, a key philanthropic partner in the region, manages this scholarship as part of its mission to promote equitable opportunities and strengthen the community through education and charitable initiatives.
Education - Higher Education Career / College Preparation Vocational & Trade Education

Clinical Trials in Organ Transplantation in Children and Adults

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Institute of Allergy and Infectious Diseases (NIAID) is advancing organ transplantation outcomes through the Clinical Trials in Organ Transplantation in Children and Adults (CTOT-CA) program. This initiative supports multicenter clinical trials and mechanistic studies related to heart, lung, kidney, liver, and intestinal transplants, as well as non-hematopoietic cellular transplantation. By exploring immune mechanisms and innovative therapies, the program aims to enhance the success and efficacy of organ transplantation.
Infectious & Parasitic Diseases Organ And Tissue Banks

Samuel “Bo” Terry Scholarship Fund

Community Foundation Serving Western Virginia
Private
United States
Approximately US $500

Samuel “Bo” Terry Scholarship Fund

Fund provides higher education scholarship assistance to needy and deserving students graduating from Roanoke City Public Schools.

Amount

  • $500+
Education - Higher Education Vocational & Trade Education Career / College Preparation

Rangeley Educational Fund

Community Foundation Serving Western Virginia
Private
United States
Approximately US $1,000

Rangeley Educational Fund

Fund provides scholarships to further the education of young men and women pursuing study in technical, vocational, academic, or professional fields.

Amount

$1,000+

Education - Higher Education Vocational & Trade Education Career / College Preparation

Southwest Missouri Resource Conservation and Development Scholarship

Community Foundation of the Ozarks Inc.
Private
United States
US $1,500
The Southwest Missouri Resource Conservation and Development Scholarship, offered by the Community Foundation of the Ozarks, provides a $1,000 scholarship for graduating high school seniors from select Missouri counties. Eligible applicants must major in Agriculture, Natural Resources, or related fields, maintain a GPA of 2.5 or higher, and submit an essay along with two letters of recommendation, one from school personnel. This scholarship aims to support students dedicated to community service and leadership.
Vocational & Trade Education Career / College Preparation Academic Scholarship Programs

Schilling Technical Scholarship

Community Foundation of the Ozarks Inc.
Private
United States
US $2,000
The Schilling Technical Scholarship, offered by the Community Foundation of the Ozarks, provides four scholarships of $2,000 each to graduating seniors from select high schools. It is renewable for an additional year if a 2.5 GPA is maintained while enrolled in at least 12 credit hours. Eligible students must demonstrate financial need and submit a FAFSA-SAI, along with a transcript and an essay. This scholarship aims to support students pursuing vocational or two-year accredited education.
Vocational & Trade Education Education - Higher Education Agricultural Education

Romero Family Scholarship Fund

Community Foundation Serving Western Virginia
Private
United States
Approximately US $2,500

Romero Family Scholarship Fund

Fund was established to provide scholarship assistance to further the education of able and deserving young men and women in their post high school education in the fields of either technical, vocational, academic or professional education, with preference given to students from Henry and Franklin Counties and the City of Martinsville.

Amount

  • $2,500+
Education - Higher Education Career / College Preparation Vocational & Trade Education

Springfield Area Foundation For Architecture Scholarship

Community Foundation of the Ozarks Inc.
Private
United States
US $1,000
The Springfield Area Foundation for Architecture Scholarship aims to support undergraduate students in their third, fourth, or fifth year majoring in Architecture. Applicants must demonstrate financial need, maintain a GPA of 3.0 or above, and be residents of specific counties. A portfolio and essay are required for submission, ensuring that the scholarship empowers talented individuals to pursue their architectural studies and contribute to the community.
Architecture Academic Scholarship Programs Education - Higher Education

Charles H. Adrean D.S.C. Post 625 Memorial Scholarship

The Community Foundation of Herkimer & Oneida Counties
Private
United States
Unspecified amount
The Charles H. Adrean D.S.C. Post 625 Memorial Scholarship, established by American Legion Post 625, honors exceptional athletes graduating from schools within New York's American Legion District 5. This scholarship supports students in their pursuit of post-secondary education, including academic, professional, and trade programs. It remains accessible to recipients entering military service, allowing them to claim it upon returning. The foundation aims to empower youth through educational opportunities that contribute to personal growth and community service.
Education - Higher Education Baseball & Softball Vocational & Trade Education

Myasthenia Gravis Network (MGNet) Scholar Program

Rare Diseases Clinical Research Network (RDCRN)
Federal Government
United States
Up to US $75,000
The Myasthenia Gravis Network (MGNet) Scholar Program is designed to enhance research capabilities in myasthenia gravis through individualized training and mentorship. Funded by the Rare Diseases Clinical Research Network (RDCRN), this program supports scholars with up to $75,000 for salary and research costs, aiming to prepare them for independent careers in clinical and translational research. Eligible candidates include MDs, PhDs, and mid-career faculty committed to advancing MG research.
Rare Diseases Immune System Diseases

The Walt Secord “Always Sunny and 75” Memorial Trade Scholarship

Midlands Community Foundation
Private
United States
US $1,000

About Us

Midlands Community Foundation (MCF) is here to serve and add value to donors’ philanthropic needs by providing them an opportunity to “invest in the power of community.” It is our goal to identify current and emerging issues, channel resources to address community needs, and help prepare for the future.

MCF Mission

The mission of Midlands Community Foundation is to be a catalyst for lasting impact in Sarpy and Cass counties and to give opportunities to organizations and individuals to pursue their charitable goals.

Scholarships Through MCF

Midlands Community Foundation is committed to the futures of communities in Sarpy and Cass Counties, and across the country. Supporting higher education of students is a direct investment in the futures of these communities.

The Walt Secord “Always Sunny and 75” Memorial Trade Scholarship Application

The Fund shall annually distribute two (2) scholarships in the amount of $1,000 each.

Vocational & Trade Education Apprenticeship & Internship Programs Educational Access & Equity

Gravelin Scholarship

Community Foundation of the Ozarks Inc.
Private
United States
Up to US $450
The Gravelin Scholarship, offered by the Community Foundation of the Ozarks, awards a $450 grant to a graduating high school senior who has faced significant life challenges, such as illness or trauma. Eligible candidates must have a minimum GPA of 3.3, show financial need via a FAFSA-SAI form, and plan to enroll in an accredited two-year, four-year, or vocational institution. Applicants are required to submit a transcript, a personal essay, and details of their community service and school involvement.
Education - Higher Education Career / College Preparation Vocational & Trade Education

KUH P30 Resource Core Center (P30 Clinical Trial Not Allowed)

National Institutes of Health
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The KUH P30 Resource Core Center funding opportunity invites applications for centers aimed at enhancing research in Kidney, Urology, and Hematology diseases. These centers will provide essential resources, including data and tools, to the research community, fostering collaboration through a national network with the Center Coordinating Hub. This initiative by the National Institutes of Health aims to drive innovative research and shared expertise for improved health outcomes.
Kidney Diseases

Gunner Lee Thomason Autism Scholarship

Community Foundation of the Ozarks Inc.
Private
United States
Up to US $700
The Gunner Lee Thomason Autism Scholarship, offered by the Community Foundation of the Ozarks, provides a $700 grant to a graduating high school senior or undergraduate student dedicated to working with autistic individuals and their families. Applicants must have a minimum GPA of 3.0 and demonstrate financial need. Preference is given to those from the Truman Lake area. The application requires a transcript, essay, letter of recommendation, and a description of community service and work experience.
Education - Higher Education Career / College Preparation Vocational & Trade Education

Polk County Tech Scholarship

Community Foundation of the Ozarks Inc.
Private
United States
Up to US $2,000
The Polk County Tech Scholarship, offered by the Community Foundation of the Ozarks, provides a $2,000 award for eligible high school seniors from select schools. This scholarship is renewable for a second year if a 2.5 GPA is maintained while enrolled in an accredited two-year or vocational program. Applicants must demonstrate financial need and submit an essay detailing their work experience and academic goals, ensuring support for those pursuing careers in technical fields.
Education - Higher Education Career / College Preparation Vocational & Trade Education

KUH U24 Center Coordinating Hub (U24 Clinical Trial Not Allowed)

National Institutes of Health
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The KUH U24 Center Coordinating Hub aims to foster collaboration among funded Centers within the NIDDK/KUHN mission. This initiative encourages the development and sharing of vital research resources, including data, reagents, and expertise, with the broader scientific community. By creating a national network, the program enhances research capabilities and promotes innovative solutions in kidney, urology, and hematology diseases.
Kidney Diseases

NIDDK Multi-Purpose Resource-Related, Multi-Component Research Services Centers Cooperative Agreement (U2C - Clinical Trial Optional)

National Institutes of Health
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NIDDK Multi-Purpose Resource-Related Research Centers Cooperative Agreement (U2C) invites applications to enhance research capabilities in areas such as obesity and diabetes. These centers provide specialized services, including technical support and data coordination, primarily to clients at other institutions lacking necessary expertise. This initiative aims to bolster high-impact research through collaboration and experiential training, addressing critical health challenges aligned with NIDDK's mission.
Kidney Diseases

Obermier Scholarship Fund in memory of John N. Obermier, Edith M. Obermier and Mary Belle Obermier

Community Foundation of Greenville
Private
United States
US $1,000

About

Community Foundation of Greenville bridges philanthropy and purpose in Greenville County, helping people make their charitable giving simpler and more powerful for 70 years. We strategically match diverse needs and opportunities in Greenville County with philanthropic resources.

Vision:

Community Foundation of Greenville will be the leading catalyst for developing assets and unlocking potential to meet the needs of an inclusive and equitable community.

Mission:

Community Foundation of Greenville improves the lives of Greenville County residents through strategic philanthropy, community investment, and collaborative leadership.

Obermier Scholarship Fund in Memory of John N. Obermier, Edith M. Obermier and Mary Belle Obermier

Purpose

Mary Belle Obermier established this scholarship with a gift from her estate in 2012. Her intent was to help academically deserving students who need financial assistance to be able to attend college and to give preference to qualified students who are committed to a career in the United States Navy. The preference for naval students is in recognition of the US Navy careers of her deceased husband, John, and his deceased first wife, Edith, who were both veterans of World War II.

Criteria:

  • Applicants must demonstrate financial need (economically disadvantaged).
  • Applicants must have a current academic GPA of 3.0 or higher.
  • Applicants must be enrolled/accepted to an institution of higher learning prior to applying.
  • Applicants must submit one letter of recommendation from a teacher, employer, or clergy.

Preference in the selection process will be given in the following order to qualified students who are:

  • students who are committed to a career in the United States Navy
  • residents of Greer, SC
  • residents of South Carolina and
  • residents of all other states
  • Education - Higher Education Educational Access & Equity Military & Veterans Services

    Undergraduate Winner's Circle Scholarships

    Iowa Foundation for Agricultural Advancement
    Association/Society
    United States
    Unspecified amount
    The Undergraduate Winner's Circle Scholarships, offered by the Iowa Foundation for Agricultural Advancement, support Iowa youth pursuing agricultural studies at 2- or 4-year institutions. Eligible applicants must be graduates of Iowa high schools or members of 4-H or FFA chapters and maintain full-time status. This initiative aims to encourage students to excel in agricultural careers by providing financial assistance tailored to their educational needs.
    Agriculture Academic Scholarship Programs Agricultural Education

    Aden, Jane and Roger, Scholarship

    Beatrice Educational Foundation
    Association/Society
    United States
    US $500
    The Aden, Jane and Roger Scholarship, offered by the Beatrice Educational Foundation, provides a $500 financial award to Beatrice High School graduating seniors actively involved in a Christian church. With a focus on financial need, applicants must maintain a minimum 3.0 GPA. Established in 1987, the Foundation supports educational opportunities within the Beatrice School District, managing a $3.8 million Endowment Fund and providing over $55,000 in scholarships annually.
    Christianity Career / College Preparation Academic Scholarship Programs

    Improving Health Outcomes in Patients with ATTR-CM Through the Development of a Shared Decision-Making Tool Grant

    Pfizer, Inc.
    Corporate
    Countries, United States
    Up to US $250,000

    Pfizer’s Core Values of Social Responsibility and Philanthropy

    About

    We’re in relentless pursuit of breakthroughs that change patients’ lives. We innovate every day to make the world a healthier place. It was Charles Pfizer’s vision at the beginning and it holds true today.

    Improving Health Outcomes in Patients with ATTR-CM Through the Development of a Shared Decision-Making Tool (Decision Aid)

    Overview

    Transthyretin Amyloid Cardiomyopathy (ATTR-CM) is a progressive, lifethreatening condition associated with significant morbidity, mortality, and burden on patients, caregivers, and healthcare systems. The multisystemic disease course is often characterized by diagnostic delays, complex treatment pathways, and evolving therapeutic options, which can create uncertainty and decisional conflict for patients and clinicians alike. Shared decision-making (SDM) has emerged as a critical component of patientcentered care1, particularly in complex and preference-sensitive conditions such as ATTR-CM. Well-designed decision aids can support meaningful dialogue between patients and healthcare professionals by improving understanding of disease trajectory, treatment options, risks and benefits, and alignment of care with individual patient values and goals.

    Rare Diseases Cardiovascular Diseases & Systems

    Large Grants for Nonprofit Organizations in California Highlights

    Looking for large grants for nonprofit organizations in California?


    Read more about each grant below or start your 14-day free trial to see all large grants for nonprofit organizations in California recommended for your specific programs.

    Last updated: October 5, 2026. Next update: November 1, 2026.

    Grant Insights : Large Grants for Nonprofit Organizations in California

    Grant Availability

    How common are grants in this category?

    Common — grants in this category appear regularly across funding sources.

    400+ Large Grants for Nonprofit Organizations in California grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

    200+ Large Grants for Nonprofit Organizations in California over $25K in average grant size

    200+ Large Grants for Nonprofit Organizations in California over $50K in average grant size

    38 Large Grants for Nonprofit Organizations in California supporting general operating expenses

    300+ Large Grants for Nonprofit Organizations in California supporting programs / projects

    400+ Grants on Instrumentl focused on Disaster Relief / Humanitarian Aid

    600+ Grants on Instrumentl focused on Food Access & Hunger

    Grant Deadline Distribution

    Over the past year, when are grant deadlines typically due for Large grants for Nonprofit Organizations in California?

    Most grants are due in the first quarter.

    Q1
    28.5%
    Q2
    25.8%
    Q3
    23.3%
    Q4
    22.4%

    Typical Funding Amounts

    What's the typical grant amount funded for Large Grants for Nonprofit Organizations in California?

    Grants are most commonly $100,000.

    $0 $0 Min.
    $100,000 $100 K Median
    $2,149,932 $2.1 M Average
    $150,000,000 $150 M Max.

    Average Grant Size

    What's the typical amount funded for California?

    Grants are most commonly $145,539.

    $145,539

    Total Number of Grants

    What's the total number of grants in Large Grants for Nonprofit Organizations in California year over year?

    In 2024, funders in California awarded a total of 256,564 grants.

    2022 237,186

    2023 236,635

    2024 256,564

    Top Grant Focus Areas

    Among all the Large Grants for Nonprofit Organizations in California given out in California, the most popular focus areas that receive funding are Education, Philanthropy, Voluntarism & Grantmaking Foundations, and Human Services.

    1. Education

    2. Philanthropy, Voluntarism & Grantmaking Foundations

    3. Human Services

    Funding Over Time

    How is funding for Large Grants for Nonprofit Organizations in California changing over time?

    Funding has increased by -1.38%.

    2022 $34,364,756,699

    2023 $37,770,770,141
    9.91%

    2024 $37,247,795,891
    -1.38%

    California Counties That Receive the Most Funding

    How does grant funding vary by county?

    Los Angeles County, San Francisco County, and San Mateo County receive the most funding.

    County Total Grant Funding in 2024
    Los Angeles County $10,841,756,858
    San Francisco County $5,409,542,294
    San Mateo County $5,358,878,304
    Santa Clara County $3,811,026,208
    Alameda County $3,749,322,182

    Related Grants in California

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