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Best Large Grants for Nonprofit Organizations in California

Find the perfect Large Grants for Nonprofit Organizations in California on Instrumentl. 11,000+ Large Grants for Nonprofit Organizations in California in the United States.

11,000+

Available grants

$3.61B

Total funding

$5K

Median grant

11,000+ grants
$3.61B total
$5K median

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10,797 Results based on applied filters

Paul and Beverly Eckert Scholarship

Quad Cities Community Foundation
Private
United States
Up to US $16,000
The Paul and Beverly Eckert Scholarship, offered by the Quad Cities Community Foundation, provides financial support of up to $4,000 annually to graduating seniors from select Davenport high schools. This scholarship is renewable for up to four years, assisting students pursuing their education at accredited colleges, universities, or trade schools. The foundation is dedicated to enhancing educational opportunities and fostering community growth through generous donor contributions.
Career / College Preparation Academic Scholarship Programs

Allianz Foundation for North America Grant

Allianz Foundation For North America
Private
Baltimore City, Maryland, Baltimore County, Maryland +13 more
US $25,000 - US $50,000
The Allianz Foundation for North America aims to empower young people by providing opportunities for personal and professional growth. Established in 2002, the Foundation focuses on enhancing the potential of youth aged 16-25 in select North American cities. Grants ranging from $50,000 to $25,000 are available for non-profit organizations that support initiatives fostering leadership, self-reliance, and social consciousness. The Foundation seeks impactful projects that address the future of communities and individuals, ensuring a secure environment for the next generation.
Youth Services Youth Development & Leadership

Ellenbecker, Oliver and Eleanor Scholarship Bachelor’s Program Fund

Noble County Community Foundation
Private
United States
US $3,500

Ellenbecker, Oliver and Eleanor Scholarship Bachelor’s Program Fund

For Noble County High School seniors (one awarded to a Central Noble High School senior, one awarded to an East Noble High School senior, one awarded to Oak Farm Montessori School senior, one awarded to a West Noble High School senior) who will be attending a four-year college or university as a full-time student. Awards $3,500 one-time.

Awards Per Year:

1 scholarship

Areas of Study:

Any

Education - Higher Education Career / College Preparation

Glass, Paul Memorial Scholarship Fund

Noble County Community Foundation
Private
United States
US $750

Glass, Paul Memorial Scholarship Fund

A one-time payment for a high school senior or undergraduate college student from Noble County who is pursuing a career in agriculture related field. Awards $750 one time. Students can reapply. 

Amount

$750

Awards Per Year:

1 scholarship

Colleges:

Any accredited college or university

Areas of Study:

Agriculture

Education - Higher Education Agricultural Education

Cancer Research Education Grants Program - Courses for Skills Development (R25 Clinical Trial Not Allowed) (350415)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $1,500,000
The Cancer Research Education Grants Program (R25) aims to enhance research education in areas crucial to the NIH mission. This program supports innovative courses that develop skills in cancer research, covering topics such as prevention, diagnosis, and treatment. Grant applications are encouraged to be creative and state-of-the-art, addressing the needs of patients and their families. Key deadlines for applications span from January 2024 to September 2026, ensuring ongoing support for educational initiatives.
Cancer / Oncology Medical Education & Professional Training

Lee Essie and Charlie McMillan, Jr. Scholarships: Medical Scholarship

Saginaw Community Foundation
Private
United States
Unspecified amount

Scholarships

Since awarding our first $500 scholarship in 1987, the Saginaw Community Foundation has awarded college scholarships to area students totaling more than $13.7 million, thanks to our generous donors. Each year, over 500 college-bound or career and technical education students benefit from our scholarship awards.

Our single application process makes it easy to potentially qualify for one or more of our 260+ scholarships.

Medical Scholarship

At a very early age in Alabama, Lee Essie Smith was a self-taught musician. After losing her mother as a young teenager, she began putting her God-given musical talent to work as a pianist for several churches. By the time she graduated from high school, she had learned the cosmetology trade and met Charlie McMillan, Jr.

After his wife’s death, Mr. McMillan continued his community service with the Democratic Party, Habitat for Humanity and Mt. Olive Baptist Church as an usher. Although he did not serve very long in the military, Mr. McMillan continues to exemplify the values and physical energy of the “Army Strong” slogan. He is the patriarch of the family – always dapper – and a regular attendee at church services.

Education - Higher Education Vocational & Trade Education Medical Education & Professional Training

Mildred Culbert Kelly & Fred W. Kelly Non-Traditional Student Scholarship

Saginaw Community Foundation
Private
United States
Unspecified amount

Scholarships

Since awarding our first $500 scholarship in 1987, the Saginaw Community Foundation has awarded college scholarships to area students totaling more than $13.7 million, thanks to our generous donors. Each year, over 500 college-bound or career and technical education students benefit from our scholarship awards.

Our single application process makes it easy to potentially qualify for one or more of our 260+ scholarships.

Mildred Culbert Kelly & Fred W. Kelly Non-Traditional Student Scholarship

Mildred Culbert Kelly and Fred W. Kelly never had children, but they were generous with contributions of time and talent to church and community groups that focused on youngsters.

Prior to his death in 1989, Mr. Kelly had been employed as an insurance agent and later purchased the Wheeler Insurance Agency which he owned and operated until his retirement in 1977. He was a founding member and past president of the Optimist Club and he assisted in establishing Big Brothers and Big Sisters of Saginaw and the READ Saginaw program.

Mrs. Kelly retired from the Accounting Department at Chevrolet Saginaw Grey Iron Foundry after 39 years of service. She volunteered at First United Methodist Church as director of the Children’s Choir, the Interpretive Choir and the Sacred Dance Group for many years. She was also a volunteer at READ Saginaw and Delta College Channel 19 and was a past president of the Opti-Mrs. Club. She died in 2000 at the age of 94.

Mildred Culbert Kelly and Fred W. Kelly’s legacy continues to assist youth with scholarships for students who might not otherwise obtain a college or Career and Technical Education (CTE) degree/certificate.

Education - Higher Education Vocational & Trade Education Adult Education

James L. Shriver Scholarship Fund

Community Foundation of Western Massachusetts
Private
United States
Up to US $3,000
The James L. Shriver Scholarship Fund, administered by the Community Foundation of Western Massachusetts, provides financial assistance to students from western Massachusetts pursuing technical careers. Eligible applicants include undergraduate or graduate students attending accredited post-secondary institutions in the U.S. Scholarships can reach up to $3,000 and may impact financial aid offers, so students should consult their college financial aid offices for guidance. This initiative supports diverse students aiming for technical fields.
Education - Higher Education Academic Scholarship Programs Vocational & Trade Education

PLTW Gateway - New Program (Phillips 66)

Project Lead The Way Inc
Private
Adams County, Colorado, Andrews County, Texas +50 more
Up to US $20,000
The PLTW Gateway program, supported by Phillips 66, aims to enhance educational equity by providing academic training in STEM fields for middle school students. The initiative focuses on empowering girls and people of color, fostering exploration of STEM pathways. Eligible schools can receive grants to start or expand their PLTW Gateway programs, ensuring they offer at least two different units over two years. Funding support includes $20,000 to enhance educational resources and training.
STEM / STEAM Education Education - Middle School

K.C. Kinch Scholarship

Silicon Valley Community Foundation
Private
San Mateo County, California
Up to US $5,000
The K.C. Kinch Scholarship, established in 2017 in memory of Kathleen Carol Kinch, provides financial assistance to students from East Palo Alto, CA. This scholarship supports high school seniors and graduates with a GPA of 3.0 to 3.75 who demonstrate financial need and community involvement. The selection committee values academic promise and aims to empower local students to pursue higher education at colleges, universities, or technical schools.
Education - Higher Education Career / College Preparation

Springfield Teachers Club Scholarship Fund

Community Foundation of Western Massachusetts
Private
United States
Up to US $3,000
The Springfield Teachers Club Scholarship Fund, managed by the Community Foundation of Western Massachusetts, supports graduates of Springfield public high schools residing in Franklin, Hampden, and Hampshire Counties. The fund offers scholarships up to $3,000 to eligible students enrolling in accredited post-secondary schools. Applicants are advised to consult with their financial aid offices, as scholarship awards may affect financial aid packages. This initiative aims to promote educational opportunities for local students.
Education - Higher Education Academic Scholarship Programs Adult Education

Enhancing Mechanistic Research on Precision Probiotic Therapies (R61/R33 Clinical Trial Optional) (356925)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $1,750,000
This grant opportunity from the NIH aims to enhance mechanistic research on precision probiotic therapies through a biphasic R61/R33 award mechanism. It encourages innovative studies to identify specific biological factors influencing probiotic responses, thereby improving clinical outcomes. The program supports up to five years of research, with the initial phase focused on discovering unique host characteristics and the second phase assessing improvements in probiotic efficacy through rigorous studies.
Integrative & Alternative Health Microbiomes

Women's Research Mentorship Grant

The Society of Interventional Radiology Foundation
Association/Society
Canada, United States
Up to US $25,000
The Women's Research Mentorship Grant by the Society of Interventional Radiology Foundation supports women in interventional radiology research, enhancing opportunities for medical students and residents. With a funding limit of $25,000, this grant encourages collaborative projects between faculty researchers and trainees, promoting a culture of inclusion. The Pre-Review process is recommended for applicants to receive feedback before final submission. Key deadlines include September 20, 2024, for Pre-Review applications and January 15, 2025, for final applications.
Biomedical Imaging Medical Education & Professional Training

George S. Souten Performing Arts Scholarship

Four County Community Foundation
Private
United States
US $1,000
The George S. Souten Performing Arts Scholarship, offered by the Four County Community Foundation, supports high school seniors from Armada, Capac, Imlay City, and Romeo who plan to major or minor in performing arts. Applicants must demonstrate a strong background in the arts and submit an essay. Awardees will be recognized during the Foundation's Scholarship Celebration in May and at their respective high school awards events.
Education - Higher Education Performing Arts Academic Scholarship Programs

Health, Patient, and Science Focused Giving

Genentech Foundation
Corporate
United States
Unspecified amount

Health, Patient, and Science Focused Giving

At Genentech, we invest in bold ideas and innovative solutions that address systemic inequities in science and medicine to advance a more just healthcare system. We focus on efforts that diversify the scientific and medical workforce, advance health equity, and help our communities thrive. We also further advance excellence in medicine and healthcare through our grants for independent medical education. Including efforts to advance health equity, support patient needs, engage the scientific community, and provide co-pay assistance. 

There are multiple ways to apply for funding. Before you submit an application, we encourage you to explore the following materials to learn more about our opportunities for funding, eligibility requirements and considerations, and the process for submitting a proposal within our Funding Request System (gFRS).

Health Disparities & Social Determinants of Health Health Care Access & Delivery

Kellly Marie Mcquate Memorial Scholarship

Quad Cities Community Foundation
Private
United States
Up to US $500
The Kellly Marie Mcquate Memorial Scholarship, offered by the Quad Cities Community Foundation, supports graduating high school seniors from Rock Island or Scott County, IL, who have lost a parent. This need-based scholarship awards up to $500 and focuses on financial need as the primary criterion. Applicants must plan to enroll full-time in college, with merit evaluated through school and community activities. This scholarship represents a significant opportunity for eligible students to pursue their educational goals.
Career / College Preparation Academic Scholarship Programs

Reineman Family Scholarship

Rochester Area Community Foundation
Private
United States
Up to US $6,000

Reineman Family Scholarship

This scholarship recognizes and provides financial support to graduating high school students who participate in Hillside Work-Scholarship Connection.

Number and Size of Awards

  • One award of $6,000; paid as $1,500 per year for up to four consecutive years of undergraduate study. Award paid in the Fall and divided equally between the Fall and Spring semesters.

Allowed Use of Award

  • Awards may be used for tuition, fees, books, and other expenses associated with higher education.
Education - Higher Education Career / College Preparation

Loren and Tammy Bockwoldt Family Scholarship

Quad Cities Community Foundation
Private
United States
Up to US $8,000
The Loren and Tammy Bockwoldt Family Scholarship, administered by the Quad Cities Community Foundation, awards up to $2,000 annually to three qualified students, totaling no more than $6,000. Applicants must be high school seniors from Durant or Wilton, Iowa, with a minimum GPA of 2.5 and demonstrated financial need. The scholarship is renewable for up to four years, supporting students aiming for full-time enrollment in accredited post-secondary institutions.
Career / College Preparation Academic Scholarship Programs

Signature & Ignition Grants

Covenant Foundation
Private
North America
Up to US $35,000
The Covenant Foundation's Signature & Ignition Grants celebrate excellence in Jewish education by funding innovative projects that enhance educational practices. The Foundation supports diverse institutions across North America, inviting applications for creative programs that can adapt and disseminate effective practices. While Signature Grants may reach up to $150,000 over three years, Ignition Grants focus on untested ideas with funding up to $20,000 for one year. One application per cycle is permitted.
Judaism Jewish Culture

Angie Van Hoven Nursing Scholarship

Community Foundation Of The Holland Zeeland Area
Private
United States
Unspecified amount

Community Foundation of the Holland/Zeeland Area

Our Mission

The Community Foundation of the Holland/Zeeland Area seeks to ensure that our community thrives today, tomorrow, and forever by building our Community’s Endowment to support high impact charitable projects, helping donors achieve their charitable goals, and leading and partnering in community-level initiatives.

Scholarships

CFHZ awards over $1 million in scholarships each year for students to attend schools of higher education throughout the nation. Our scholarships are possible thanks to the generosity of donors who invest in our community’s future by furthering the education of others.

All Holland/Zeeland area individuals interested in post-secondary education are encouraged to apply for CFHZ scholarships.

The Foundation proudly administers over 100 scholarships, each with unique eligibility criteria that must be met before a candidate can be considered.

Angie Van Hoven Nursing Scholarship

  • Graduating Zeeland East High School or Zeeland West High School senior, regardless of the school district in which the student resides, or a graduating senior who resides in the Zeeland Public School District and attends Holland Christian High School
  • Enrolling at an accredited post-secondary school within the United States
  • Planning to pursue a post-secondary degree in nursing
  • Potentially renewable for three additional years
Education - Higher Education Nursing

St. Julian and Adrienne Simpkins Book Award

Rochester Area Community Foundation
Private
United States
Up to US $500

St. Julian and Adrienne Simpkins Book Award

To provide book awards to students pursuing higher education.

Number and Size of Awards

Up to five awards of $500 each; paid in one lump sum in the Fall semester.

Allowed Use of Award

Awards may be used for college textbook expenses.

Education - Higher Education Career / College Preparation

Louis P. and Betty A. Iacona Nursing Scholarship

Rochester Area Community Foundation
Private
United States
US $4,000 - US $12,000

Louis P. and Betty A. Iacona Nursing Scholarship

To provide financial assistance to students in Monroe County pursuing a career in nursing.

Number and Size of Awards

One award of $12,000; divided into equal annual installments paid over four consecutive years of undergraduate study. Award may be split between two recipients and is paid in the Fall and divided equally between the Fall and Spring semesters. Minimum award $4,000; paid as $1,000 per year for up to four years.

Allowed Use of Award

Awards may be used for tuition, fees, books, and other expenses associated with higher education.

Education - Higher Education Nursing

Lorraine Halsch Memorial Scholarship

Rochester Area Community Foundation
Private
United States
US $4,000 - US $6,000

Lorraine Halsch Memorial Scholarship

To provide financial assistance to college-bound students who have overcome adversity (i.e., family tragedy, illness, etc.).

Number and Size of Awards

One award of $6,000; divided into equal annual installments paid over four consecutive years of undergraduate study. Award may be split between two or three recipients and is paid in the Fall and divided equally between the Fall and Spring semesters. Minimum award $4,000; paid as $1,000 per year for up to four years.

Allowed Use of Award

Awards may be used for tuition, fees, books, and other expenses associated with higher education.

Education - Higher Education Career / College Preparation

KajjecK Scholarship

Rochester Area Community Foundation
Private
United States
Up to US $4,000

KajjecK Scholarship

To provide financial assistance to Rochester City School District students pursuing a college degree. 

Number and Size of Awards

One award of $4,000; paid as $1,000 per year for up to four consecutive years of undergraduate study. Award paid in the Fall and divided equally between the Fall and Spring semesters. ***Offered in even years. ***

Allowed Use of Award

Awards may be used for tuition, fees, books, and other expenses associated with higher education.

Education - Higher Education Career / College Preparation

Frances R. Dewing Foundation Grant

Francis R. Dewing Foundation
Private
United States
Unspecified amount
The Francis R. Dewing Foundation Grant provides seed money to support innovative projects in early childhood education, benefiting children up to sixth grade. Founded by Frances R. Dewing in 1963, the foundation aims to stimulate intellectual growth in young children through unique educational methods. Grants typically range from $1,000 to $25,000, with a focus on projects that demonstrate a broad impact on the educational community. Applications are accepted from 501(c)(3) nonprofit organizations and government entities across the United States.
Education - Preschool / Early Learning Education - Elementary School

Bessie Minor Swift Foundation Grant

Bessie Minor Swift Foundation
Corporate
Ada County, Idaho, Canyon County, Idaho +2 more
US $500 - US $5,000
The Bessie Minor Swift Foundation Grant supports programs that enhance literacy and educational enrichment in communities served by Swift Communications. Grants are available to nonprofit organizations focused on developing literacy skills, STEM education, and interdisciplinary programs for children and youth. With funding ranging from $500 to $5,000, the foundation prioritizes initiatives that foster active citizenry and provide direct service to underserved populations.
Literacy STEM / STEAM Education Art Education

Centers of Excellence in Healthcare Quality and Safety

Dept. of Health & Human Services: Centers for Disease Control & Prevention
Federal Government
American Samoa, Guam +4 more
US $3,500,000 - US $22,000,000
The Centers of Excellence in Healthcare Quality and Safety program aims to establish a collaborative network of healthcare systems and public health partners to enhance patient and healthcare worker safety. This initiative focuses on improving the quality and resilience of U.S. healthcare delivery across various settings, including hospitals and outpatient facilities. By fostering partnerships, the program seeks to effectively detect, respond to, and prevent safety threats, ensuring a higher standard of care and safety for all.
Health Care Access & Delivery Rural Health Care

Large Grants for Nonprofit Organizations in California Highlights

Looking for large grants for nonprofit organizations in California?


Read more about each grant below or start your 14-day free trial to see all large grants for nonprofit organizations in California recommended for your specific programs.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Large Grants for Nonprofit Organizations in California

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

400+ Large Grants for Nonprofit Organizations in California grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

200+ Large Grants for Nonprofit Organizations in California over $25K in average grant size

200+ Large Grants for Nonprofit Organizations in California over $50K in average grant size

38 Large Grants for Nonprofit Organizations in California supporting general operating expenses

300+ Large Grants for Nonprofit Organizations in California supporting programs / projects

400+ Grants on Instrumentl focused on Disaster Relief / Humanitarian Aid

600+ Grants on Instrumentl focused on Food Access & Hunger

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Large grants for Nonprofit Organizations in California?

Most grants are due in the first quarter.

Q1
28.5%
Q2
25.8%
Q3
23.3%
Q4
22.4%

Typical Funding Amounts

What's the typical grant amount funded for Large Grants for Nonprofit Organizations in California?

Grants are most commonly $100,000.

$0 $0 Min.
$100,000 $100 K Median
$2,149,932 $2.1 M Average
$150,000,000 $150 M Max.

Average Grant Size

What's the typical amount funded for California?

Grants are most commonly $145,539.

$145,539

Total Number of Grants

What's the total number of grants in Large Grants for Nonprofit Organizations in California year over year?

In 2024, funders in California awarded a total of 256,564 grants.

2022 237,186

2023 236,635

2024 256,564

Top Grant Focus Areas

Among all the Large Grants for Nonprofit Organizations in California given out in California, the most popular focus areas that receive funding are Education, Philanthropy, Voluntarism & Grantmaking Foundations, and Human Services.

1. Education

2. Philanthropy, Voluntarism & Grantmaking Foundations

3. Human Services

Funding Over Time

How is funding for Large Grants for Nonprofit Organizations in California changing over time?

Funding has increased by -1.38%.

2022 $34,364,756,699

2023 $37,770,770,141
9.91%

2024 $37,247,795,891
-1.38%

California Counties That Receive the Most Funding

How does grant funding vary by county?

Los Angeles County, San Francisco County, and San Mateo County receive the most funding.

County Total Grant Funding in 2024
Los Angeles County $10,841,756,858
San Francisco County $5,409,542,294
San Mateo County $5,358,878,304
Santa Clara County $3,811,026,208
Alameda County $3,749,322,182

Related Grants in California

Browse Other Nonprofit Operations & Capacity Grants in California

Browse Grants For Nearby Locations

Browse Grants by Major US Cities within California