Best Operating Grants for Nonprofits in California

Oregon Department of Forestry

Vision: Complex and resilient forest ecosystems that endure and adapt.

Mission: To protect and promote resilient forests that benefit all Oregonians.

US Dept. of Transportation Grant - Safe Streets and Roads for All (SS4A) Grant Program

The purpose of this Notice of Funding Opportunity is to solicit applications for Safe Streets and Roads for All (SS4A) grants.

Funds for the fiscal year (FY) 2026 SS4A grant program are to be awarded on a competitive basis to support planning, infrastructural, behavioral, and operational initiatives to prevent death and serious injury on roads and streets involving all roadway users, including pedestrians; bicyclists; public transportation, personal conveyance, and micromobility users; motorists; and commercial vehicle operators.

The SS4A Grant Program includes: 1) Planning and Demonstration Grants; and 2) Implementation Grants.

Implementation Grants

Implementation Grants fund projects and strategies identified in an Action Plan that address roadway safety problems. Implementation Grants may also fund supplemental planning and demonstration activities, as well as project-level planning, design, and development activities for projects and strategies identified in an Action Plan (e.g., project-level 21 National Environmental Policy Act (NEPA) compliance, associated environmental review activities, permits and approvals, construction design, etc.). 

• Expected number of awards: 40 to 70

Oregon Department of Forestry

Vision: Complex and resilient forest ecosystems that endure and adapt.

Mission: To protect and promote resilient forests that benefit all Oregonians.

US Dept. of Transportation Grant - Safe Streets and Roads for All (SS4A) Grant Program

The purpose of this Notice of Funding Opportunity is to solicit applications for Safe Streets and Roads for All (SS4A) grants.

Funds for the fiscal year (FY) 2026 SS4A grant program are to be awarded on a competitive basis to support planning, infrastructural, behavioral, and operational initiatives to prevent death and serious injury on roads and streets involving all roadway users, including pedestrians; bicyclists; public transportation, personal conveyance, and micromobility users; motorists; and commercial vehicle operators.

The SS4A Grant Program includes: 1) Planning and Demonstration Grants; and 2) Implementation Grants.

Planning and Demonstration Grants

Planning and Demonstration Grant Eligibility Requirements

Eligible activities for a Planning and Demonstration Grant include: develop a new Action Plan, conduct supplemental safety planning to update an existing Action Plan, or carry out safety demonstration activities to inform the development of or update to an Action Plan.

These activities may be bundled in any combination, provided that the requirements in this Notice are met. DOT encourages complementary but distinct activities, including but not limited to safety demonstration activities that will help inform the development of an Action Plan. Any applicant that meets the eligibility requirements may apply for a Planning and Demonstration Grant to develop an Action Plan. 

• Expected number of awards: 400 to 700

Affordable Housing Development Program – Notice of Funding Opportunity

The Department of Public Works and Planning’s (PWP) Community Development Division (Division), on behalf of the County of Fresno (County), is pleased to announce funding opportunities for the new development or preservation of affordable housing. Restrictions on Project Location apply.

This NOFO is intended to streamline four affordable housing development programs (each with slightly different underlying regulations) to align eligibility criteria, ranking, and release of funds, allowing for a coordinated single application and reservation process.

This information is specific to the Department of Public Works and Planning Community Development Division and is not inclusive of funding administered by other County departments.

Funding is anticipated to be available for affordable housing development projects under the following programs:

• Permanent Local Housing Allocation (PLHA) (Funds 100% Reserved, New Funds Pending )
• A State Department of Housing and Community Development (HCD) funding source.
• HOME Investment Partnerships Program (HOME) (Funds Available, BABA Applies)
• A Federal Department of Housing and Urban Development (HUD) funding source.
• HOME Community Housing Development Organization (HOME-CHDO) (Funds Available, BABA Applies)
• A Federal HUD HOME funding source, reserved for County-certified CHDO-eligible projects.
• HOME – American Rescue Plan (HOME-ARP) (Funds 100% Reserved)
• A Federal HUD HOME funding source with special requirements and 4 Qualifying Populations

Who is this information for?

• For Profit and Non-Profit developers of affordable housing.
• If you are a landowner without development experience, let's talk!

The Susie Kubié Symphonic Music Scholarship, established in 2017, provides financial support to talented young musicians from the Albuquerque Youth Symphony Program (AYSP). Each year, up to $4,000 is awarded to new or renewing scholars pursuing a music degree. Applicants are required to submit a personal essay, letters of reference, and a video performance. This scholarship not only aids students in their educational pursuits but also honors Susie Kubié's legacy of dedication to music education.

The Sidney R. Baer, Jr. Foundation offers Social Support Grants aimed at improving the lives of individuals living with schizophrenia and bipolar disorder. These grants focus on reducing stigma through education and advocacy, fostering a compassionate environment. The foundation prioritizes organizations that provide tangible support and resources, ensuring a meaningful impact on mental health. By addressing the challenges faced by those with mental illness, the foundation strives to create a more inclusive society that recognizes and supports their needs.

Farmer First Regenerative Pilot Program

Regenerative Agriculture is a conservation management approach that emphasizes natural resources through improved soil health, water management, and natural vitality for the productivity and prosperity of American agriculture and communities.

In December 2025, NRCS launched the NRCS Regenerative Pilot Program, a farmer first, outcomes-based approach to conservation designed to return the agency to its core mission – helping people help the land. NRCS is investing $700 million to specifically support regenerative agriculture, including:

• $400 million through the Environmental Quality Incentives Program (EQIP); and
• $300 million through the Conservation Stewardship Program (CSP)

This pilot program addresses whole-farm resource concerns through support for voluntary regenerative agriculture conservation plans. It also puts American farmers first as a part of the solution to Make American Healthy Again (MAHA) by supporting access to American-grown whole foods, critical to addressing the chronic disease crisis nationwide.

For too long, divided and highly specific funding pools have unintentionally encouraged isolated, practice-by-practice conservation, rather than holistic management. By integrating bundled regenerative practices into single applications, closing program loopholes, and recognizing outcomes, NRCS will deliver lasting benefits for farmers, natural resources, and the American consumer.

Emphasizing regenerative agriculture builds upon NRCS’s 90 years of existing conservation work by restoring land health, improving long-term productivity, and ensuring American grown production for the future. 

The contract length will be a minimum of 5 years.

Mr. Holland’s Opus Foundation

Who knew that a movie made 30 years ago would become the catalyst for the creation of a namesake non-profit, changing the lives of hundreds of thousands of kids by giving them access to learn and play music in school – keeping music education alive and strong across the country?

Mr. Holland’s Opus Foundation was inspired by the acclaimed motion picture Mr. Holland’s Opus, the story of the profound effect a dedicated music teacher had on generations of students. Michael Kamen, who wrote the score for the film, started the foundation in 1996 as his commitment to the future of music education.

The Foundation donates high-quality musical instruments to deserving, under-funded music programs, and provides an array of support services to school districts. By increasing the school’s inventory of quality, playable instruments, music teachers are given the tools they need to deliver a quality music education to students who want to learn. In collaboration with committed school districts, the Foundation’s investments are strategically placed as part of a K–12 district-wide plan to achieve positive and lasting results. Generations of students will benefit.

Instrument Grants

Mr. Holland’s Opus Foundation donates musical instruments to schools nationwide with a focus on increasing student access to music education programs in low-income communities.

Mr. Holland’s Opus Foundation grants consist of musical instruments and equipment only; no cash grants are provided. Our team handles sourcing, ordering, and delivering the instruments. As part of the application process, we work with the teacher to assess the program’s needs to determine the appropriate instruments and equipment. Note that only student model instruments are provided, and the brand is at the Foundation’s discretion.

The Michigan Professional Insurance Agents Scholarship (MIPIA) is offered by the Four County Community Foundation to seniors and recent graduates in Michigan planning to major in Insurance/Risk Management. This scholarship provides up to four awards and aims to foster education in the insurance field. Award recipients will be honored at the Foundation Scholarship Celebration in May, ensuring recognition of their achievements and contributions to the community.

The Bernice Ash Memorial Award honors the legacy of a retail music visionary by providing a $5,000 grant to mid-career professionals employed by NAMM member companies. This award aims to support emerging leaders in the music industry through professional development opportunities and a one-year mentorship with NAMM Young Professionals. Eligible applicants must have at least five years of experience and agree to use the funds for professional training, enhancing their leadership skills and career growth.

The Arts Performance and Exhibition Spaces (APEX) Grant supports arts and culture nonprofits in the Bay Area, offering flexible funding for operations and artist compensation. Grants range from $10,000 to $15,000, aimed at organizations with budgets between $500,000 and $2 million. The program prioritizes diverse artistic expressions and supports historically marginalized groups. Applications are due annually by January 15, with letters of inquiry due by December 1, promoting the production of new works by local artists.

The Kei Lin Foundation Grant, established in 2012 by Margaret Tsai, honors her mother, Kei Lin. This grant supports charitable organizations that provide essential services such as housing, food, and medical assistance to senior citizens and veterans. Priority is given to tax-exempt organizations under 501(c)(3) status. Applicants must adhere to specific guidelines and provide regular reports on fund usage to ensure transparency and accountability in their operations.

The Chronic Lymphocytic Leukemia Fund, managed by the HealthWell Foundation, aims to alleviate financial burdens for underinsured patients battling chronic lymphocytic leukemia (CLL). This fund provides essential support for prescription copays and premiums, ensuring that patients can access necessary treatments without the stress of financial constraints. Since its inception, the foundation has awarded over $1.2 billion in grants, helping more than 1.1 million patients. The initiative emphasizes the importance of accessible healthcare and aims to improve the quality of life for those affected by this condition.

The Congenital Sucrase-Isomaltase Deficiency Fund, managed by the HealthWell Foundation, aims to alleviate financial burdens for underinsured patients suffering from this genetic disorder. By providing assistance with prescription drugs and treatment costs, the fund ensures that vital medications are accessible, allowing patients to manage their condition effectively. In 2024, the Foundation is expected to award over $1.2 billion in grants, showcasing its commitment to enhancing healthcare access for those in need.

The U.S. Department of Health & Human Services, through the NIH, invites applications for the U01 grant aimed at advancing gene-based therapies for ultra-rare neurological and neuromuscular disorders. This initiative focuses on IND-enabling studies and supports the development of innovative therapeutics with proven biological rationale. Applications must include robust data and compelling justification for the proposed clinical candidates, targeting a specific patient population to facilitate IND filing and subsequent clinical trials.

The Measurement and Evaluation Graduate Student Award, offered by SHAPE America, aims to support graduate students specializing in psychomotor measurement and evaluation. This scholarship assists with professional expenses, ensuring candidates can focus on their studies. Eligible applicants must be current SHAPE America members and pursuing relevant master's or doctoral degrees. The award prioritizes those who have completed their first year of study, promoting excellence in health and physical education across the U.S.

The NASPGHAN Foundation Abbott Advanced Fellowship in Pediatric Nutrition offers up to $75,000 for one year of advanced training in pediatric nutrition for members of NASPGHAN. This fellowship aims to enhance pediatric nutrition expertise by supporting a well-defined clinical experience and focused research project. Eligible applicants must be MDs or DOs and members in good standing, with a preference for those seeking training at different institutions. This initiative addresses the increasing importance of pediatric nutrition in child health.

The Variety Sunshine Coach Grant Program aids children with special needs in Southern California by providing essential resources for mobility, education, and healthcare. Celebrating over 30 years, this initiative offers specially equipped Sunshine Coaches to transport children to necessary services. Organizations must be 501(c)(3) and demonstrate a commitment to serving children aged 0-18. By removing barriers, the program ensures inclusivity and opportunity for every child in the community.

Raley's Community Giving supports impactful community initiatives in areas such as child welfare, food access, and sustainability. They prioritize requests that align with these focus areas and require submissions to be made at least 90 days prior to the need date. Organizations must be located in cities with Raley's stores and can only receive support once per fiscal year. Notably, requests for individual sponsorships or third-party fundraising are not eligible.

This grant opportunity aims to address health and healthcare disparities in non-communicable and chronic diseases in Latin America. It encourages innovative, collaborative research in clinical epidemiology and healthcare policy evaluation. With focused deadlines for standard, renewal, and AIDS-related applications, the program seeks multidisciplinary teams that include key partners from Latin American institutions to enhance health outcomes across the hemisphere.

The Pasadena Community Foundation offers Animal Welfare Grants on even years to support nonprofits focused on wildlife welfare and habitat conservation in the greater Pasadena area. Grants range from $5,000 to $15,000 for organizations that create conservation corridors, protect species, and enhance biodiversity. Eligible applicants must be tax-exempt and serve areas defined by the Pasadena Unified School District. This initiative aims to foster a compassionate community for all animals through impactful projects.

The Dave McGillivray Finish Strong Foundation provides grants to organizations focused on inspiring youth through physical activity, literacy, and community engagement. With a mission to empower children in New England, the Foundation awards grants of up to $5,000 twice a year. Priority is given to programs serving individuals under 17, particularly in areas with low reading scores and high poverty. This initiative fosters self-confidence and community support, ensuring a brighter future for the youth it serves.

The Downing-Nix Trust Grant provides funding for organizations engaged in research on muscular dystrophy, maintaining treatment wards in Atlanta hospitals, offering veterinary medicine scholarships, and supporting shelters for small animals. Organizations must qualify as 501(c)(3) charities. Applications are accepted year-round, but submissions by April 15 are required for annual meeting reviews. Priority may be given to hospitals and veterinary schools within Atlanta, GA.

The Nicholson Family Foundation Grant supports organizations that empower underserved youth in arts, education, and social services across Northern California. Established in 1996, the foundation provides small grants that create meaningful impacts, reinforcing community ties. Eligible organizations may reapply every three years, ensuring ongoing support for impactful initiatives. The foundation prioritizes operational support and encourages collaborations with new organizations, fostering a sustainable philanthropic environment.

The Avant Garde Award supports innovative research on HIV and substance use disorders, encouraging creative scientists to explore high-risk, high-reward approaches. While applications are not currently being accepted, this initiative by the National Institute on Drug Abuse (NIDA) aims to stimulate collaborations and impactful research. Early-stage investigators are particularly encouraged to consider this opportunity as they develop their proposals for future funding. The program uses the DP1 activity code, fostering transformative advancements in biomedical and behavioral science.

The San Fernando Valley Audubon Society Scholarship aims to support young conservationists aged 18-24 pursuing higher education. The program offers three scholarships of $500 each for tuition, lab fees, or necessary supplies for the Fall Semester. While membership in SFVAS is a plus, it is not mandatory. Applicants must demonstrate recent conservation efforts and provide proof of residency within the catchment area. This initiative fosters environmental stewardship and empowers the next generation of conservation leaders.

The PNC Foundation's Grow Up Great Grant is a significant initiative aimed at enhancing educational opportunities for children from birth to age 5. With a commitment of $500 million, this program focuses on improving school readiness through support in vocabulary development, social-emotional learning, and the arts. By partnering with community-based nonprofits, PNC aims to foster stronger, smarter, and healthier communities, ensuring a brighter future for the next generation.

The Diversity Mentorship Grant Program aims to enhance ethnic diversity in dermatology by providing mentorship to underrepresented medical students. Participants receive 160 hours of hands-on experience with a dermatologist, fostering a deeper understanding of the field. A stipend of $1,500 is available for travel and living expenses. Applications are open until November 1 for the upcoming year, encouraging students from diverse backgrounds, including Black, Hispanic, and Native American groups, to apply.