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Best Grants for Nonprofits Serving Disabled in South Carolina

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Last updated: October 5, 2026. Next update: November 1, 2026.

AI summary from publicly available grant information

Unspecified amount

Creag Foundation Innovation Grants in South Carolina

Rolling deadline
Nonprofit 501(c)(3) organizations with innovative approaches to human services and social problems in South Carolina can seek funding from the Creag Foundation. Focused on new ways to address societal issues, this private foundation invites letters of inquiry from smaller or evolving programs, which may include disability care and services or support for children with disabilities.
Creag Foundation

Up to US $15,000

DanPaul Foundation Grants

Rolling deadline
The DanPaul Foundation aims to enhance early childhood development by training teachers and parents, protecting children from abuse, and promoting social responsibility. They provide grants to non-profits for programs that focus on education, health, and welfare of youth. Key initiatives include scholarships, environmental education, and support for underprivileged children. Grant amounts range from a few hundred dollars to $15,000 annually, with a focus on impactful, community-driven projects.
The Dan Paul Foundation

Up to US $100,000

Tech-Enabled Social Impact Funding from Cisco

Rolling deadline
Nonprofits and NGOs using technology to address crisis response, education access, economic empowerment, or climate resilience worldwide, including South Carolina, can apply for Global Impact Cash Grants of up to US $100,000. Cisco Systems Foundation supports innovative, early-stage, tech-enabled programs serving predominantly economically underserved communities, with applications accepted year-round via an initial LOI.
Cisco Systems Foundation

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More than US $100,000

Hearst Foundation: Culture Grant

Rolling deadline
The Hearst Foundation: Culture Grant aims to support outstanding nonprofits that enhance cultural engagement and artistic talent in the U.S. With a focus on programs that reach young people, the grant prioritizes organizations that create lasting impacts in the arts and sciences. The Foundation allocates 25% of its funding to cultural initiatives, favoring established organizations with a history of significant results. Eligible nonprofits must encourage inclusivity and sustainability in their programs.
William Randolph Hearst Foundation

More than US $100,000

Hearst Foundation: Social Service Grant

Rolling deadline
The Hearst Foundation's Social Service Grant focuses on tackling chronic poverty by funding direct-service organizations that implement effective solutions for economic independence and family strengthening. With a mission to support diverse nonprofits in the U.S., the Foundation allocates approximately 15% of its total funding to social services, prioritizing scalable programs that serve significant populations. The minimum grant size is $100,000, and special consideration is given to organizations addressing affordable housing, domestic violence, and youth development.
William Randolph Hearst Foundation

Unspecified amount

South Carolina Community Health Funding via Labcorp

Rolling deadline
Nonprofit organizations working in health, education, or community services in South Carolina can access funding through Labcorp Charitable Foundation to support food pantries, healthcare for underserved populations, STEM programs, and healthy lifestyle initiatives. U.S.-based 501(c)(3) organizations serving disabled individuals through these activities may be eligible to apply.
Labcorp Charitable Foundation

Unspecified amount

PNC Foundation: Foundation Grant

Rolling deadline
The PNC Foundation aims to enhance the lives of individuals in local communities through partnerships with nonprofit organizations. Their focus includes promoting educational opportunities, particularly for early childhood education, and supporting economic development initiatives. Grants are available for organizations that benefit low- to moderate-income families and enhance community growth. The foundation prioritizes programs that foster sustainability and diversity, ensuring a lasting impact on the communities they serve.
PNC Foundation

Unspecified amount

Semnani Family Foundation Grants

Rolling deadline
The Semnani Family Foundation, established in 1993, is dedicated to supporting marginalized communities worldwide through health, education, and disaster relief initiatives. Founded by Khosrow and Ghazaleh Semnani, it began by funding an orphanage in Romania. The foundation also operates locally, providing free healthcare through the Maliheh Free Clinic in Utah. Its commitment to human welfare drives impactful partnerships in countries such as Afghanistan, India, and South Africa, focusing on the most vulnerable populations.
Semnani Family Foundation

Unspecified amount

Sidney Stern Memorial Trust Grants for South Carolina Nonprofits

Rolling deadline
Nonprofit 501(c)(3) organizations funding charitable, scientific, medical, or educational programs in South Carolina that use funds within the U.S. may be eligible for this support. With a mission to strengthen charitable, scientific, medical, and educational work, Sidney Stern Memorial Trust provides tax-exempt organizations with project or program funding that could benefit disability-related services.
Sidney Stern Memorial Trust

Unspecified amount

The Bank of America Foundation Sponsorship Program

Rolling deadline
The Bank of America Foundation Sponsorship Program aims to enhance economic mobility and social progress in low- and moderate-income communities through partnerships with nonprofit organizations. This initiative focuses on critical areas such as workforce education, basic needs like food and housing, and community development. The Foundation invested $350 million last year and encourages employee volunteerism and giving, supporting nonprofits in various sectors, including arts, culture, and diversity initiatives.
Bank Of America Charitable Foundation Inc

Unspecified amount

South Carolina Human Services Funding via Robinson Foundation

Applications due Oct 15, 2026
South Carolina 501(c)(3) nonprofits serving people in need can access funding through Robinson Foundation for programs in areas like children and families, education, medical assistance, poverty relief, and disaster relief. Eligible organizations must serve the Southern region, be operating for more than three years, and seek single-year, non-capital support that shows tangible, meaningful impact.
Robinson Foundation

Unspecified amount

Dudley T. Dougherty Foundation Grant

Applications due Oct 31, 2026
The Dudley T. Dougherty Foundation Grant supports nonprofit charitable organizations recognized under section 501(c)(3) of the IRS Revenue Code. Established in 2002, the foundation aims to empower groups committed to positive change, fostering respect for life and the environment. Their vision emphasizes collaboration for a better future, encouraging applicants to embody these values in their initiatives. With a focus on impactful projects, this grant is an opportunity for organizations striving to make a critical difference in our world.
Dudley T Dougherty Foundation Inc

Unspecified amount

Georgia-Pacific Foundation Grant

Applications due Oct 31, 2026
The Georgia-Pacific Foundation Grant supports organizations in the Metro Atlanta area, focusing on education, entrepreneurship, community enrichment, and environmental sustainability. Established in 1958, the foundation prioritizes investments that align with its mission and values, promoting long-term well-being within communities where Georgia-Pacific operates. Eligible applicants include 501(c)(3) nonprofits, public schools, and local government entities located within 30 miles of GP manufacturing sites.
Georgia-Pacific Foundation

Unspecified amount

Basic Needs and Youth Grants from TJX Foundation

Letter of inquiry due Oct 31, 2026
Nonprofit 501(c)(3) organizations supporting basic needs, at-risk youth, or domestic violence services near TJX locations, including South Carolina, can seek program funding that helps vulnerable families and children. The TJX Foundation considers letters of inquiry from eligible groups within 15 miles of a store, distribution center, or office that align with its community mission.
The Tjx Foundation Inc

US $5,000 - US $10,000

Lawrence Foundation Support for Community Services

Applications due Nov 1, 2026
Nonprofit 501(c)(3) organizations, public schools, and libraries can seek unrestricted program or operating support for environmental, human services, and related work from the Lawrence Foundation; awards typically range from US $5,000 - US $10,000. With a mission to support environmental and human services causes, this private family foundation accepts applications nationwide, and South Carolina disability-service nonprofits may be eligible if their programs fit these priorities.
Lawrence Foundation

US $25,000 - US $100,000

South Carolina Disability Services Funding via Honda USA Foundation

Applications due Nov 1, 2026
Nonprofit 501(c)(3) organizations and schools supporting disability care and services in South Carolina can apply for Honda USA Foundation’s Mobility Pillar Award, with grants of US $25,000 - US $100,000 for programmatic support. Grants fund education, awareness, and infrastructure programs like therapeutic or adaptive services, comprehensive care, and mobility modifications or assistive technology benefiting communities where Honda associates live and work.
Honda USA Foundation

US $1,000 - US $20,000

Max and Victoria Dreyfus Foundation Grants for South Carolina Disability Programs

Applications due Nov 11, 2026
Max and Victoria Dreyfus Foundation provides South Carolina disability care and services nonprofits with US $1,000 - US $20,000 to support community-based programs. IRS-qualified U.S. organizations serving people with disabilities, including youth and seniors, may seek funding for education, skills training, cultural activities, health facilities, and related services that benefit local communities.
Max and Victoria Dreyfus Foundation

US $250 - US $5,000

Spark Good: Strengthening Community - Local Grants

Applications due Nov 30, 2026
The Spark Good: Strengthening Community Local Grants program by the Wal-Mart Foundation empowers local organizations through grants ranging from $250 to $5000. This initiative aims to enhance community welfare by supporting diverse projects, including animal shelters and educational programs. Eligible organizations must have a verified Spark Good account, ensuring funds are allocated effectively to meet local needs and foster community development. Together, we can create lasting impacts through small yet significant actions.
Wal-Mart Foundation

Up to US $15,000

Summer Arts Education Funding for Nonprofits from South Carolina Arts Commission

Applications due Dec 18, 2026
Nonprofit community-based organizations, colleges, universities, and government units in South Carolina can receive up to US $15,000 from the South Carolina Arts Commission to run summer K-12 arts education projects. Funding can support workshops, camps, residencies, public art, performances, exhibitions, equipment, planning, or professional development, including programs serving disabled children and youth.
South Carolina Arts Commission

US $5,000 - US $25,000

Dr Scholl Foundation Grants for Community Programs

Letter of inquiry due Feb 1, 2027
Nonprofit 501(c)(3) organizations can seek US $5,000 - US $25,000 to support education, social services, health care, civic, cultural, or environmental projects, primarily in the U.S., including South Carolina. Grants from Dr Scholl Foundation help South Carolina disability care and children’s disability programs that fit these categories secure one-year project funding.
Dr Scholl Foundation

Approximately US $3,200

Coastal Community Foundation Grants for South Carolina Equity

Applications due Feb 3, 2027
Nonprofit 501(c)(3) organizations serving residents of Charleston, Berkeley, or Dorchester counties can seek funding for programs tackling structural racism and economic inequality, including those impacting disabled people. Grants from Coastal Community Foundation help South Carolina community programs build or strengthen collaborative partnerships, with awards of approximately US $3,200 through the Lowcountry Unity Fund.
Coastal Community Foundation of South Carolina

Up to US $2,500

South Carolina Arts Commission Grants for Accessibility

Applications due Mar 26, 2027
South Carolina nonprofits and government units improving arts accessibility for people with disabilities in South Carolina can access funding through the South Carolina Arts Commission, with awards up to US $2,500. Grants reimburse program and facility costs like assistive technologies, accessible materials, staff training, and capital improvements that remove barriers for disabled participants.
South Carolina Arts Commission

Unspecified amount

O'Reilly Automotive Foundation Grant

Applications due Apr 15, 2027
The O'Reilly Automotive Foundation Grant focuses on enhancing community welfare through philanthropic initiatives that support economic stability, workforce development, health services, and disaster relief. Established in 2020, the Foundation seeks to empower underrepresented individuals and organizations in the U.S. by addressing vital community needs. It particularly aims to provide assistance to nonprofits that foster positive change and improve quality of life for those in need, ensuring a lasting impact in local communities.
O'Reilly Automotive Foundation Inc

Up to US $50,000

BECU Foundation Community Grants in South Carolina

Letter of inquiry due Apr 24, 2027
Nonprofit 501(c)(3) organizations providing community programs, including disability services, in Charleston County, South Carolina can receive up to US $50,000 for work that strengthens local communities, meets basic needs, or advances education and wellness. BECU Foundation’s People Helping People Awards require nomination by a BECU member and focus on impactful, non-discriminatory programs.
BECU Foundation

Up to US $100,000

Yawkey Foundation Support for Human Services

Letter of inquiry due Jun 19, 2027
Nonprofit 501(c)(3) organizations providing direct human services, basic needs, and social services in Georgetown County, South Carolina can seek funding for discrete program or small capital needs. Grants from Yawkey Foundation help cover timebound projects or equipment aligned with an organization’s mission, with awards up to US $100,000 for high-impact work serving vulnerable and underserved people.
Yawkey Foundation

Up to US $15,000

Disability Services Funding from Community Foundation

Pre proposal due Jul 15, 2027
South Carolina nonprofits and public entities serving people with disabilities, health needs, or other human services can seek up to US $15,000 for programs in Aiken and Edgefield counties. Organizations working in areas like disability care, medical clinics, mental health, rehabilitation, or services for people in need apply through the Community Foundation for the Central Savannah River Area’s competitive Community Grants program.
Community Foundation for the Central Savannah River Area

US $5,000 - US $250,000

South Carolina Disability Services Funding via Gupta Family Foundation

Applications due Jul 31, 2027
Nonprofit organizations working on disability care and services, poverty alleviation, or humanitarian aid can seek US $5,000 - US $250,000 to help disadvantaged people become more self-reliant. With a mission to support focused interventions, Gupta Family Foundation provides grants to smaller organizations worldwide, including U.S. 501(c)(3)s that meet its revenue, leadership, and non-sectarian criteria.
Gupta Family Foundation

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Grants for Nonprofits Serving Disabled in South Carolina Highlights

Looking for grants for nonprofits serving disabled in South Carolina?


Read more about each grant below or start your 14-day free trial to see all grants for nonprofits serving disabled in South Carolina recommended for your specific programs.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Grant Funding Trends in South Carolina

Average Grant Size

What's the typical amount funded for South Carolina?

Grants are most commonly $74,506.

$74,506

Total Number of Grants

What's the total number of grants in Grants for Nonprofits Serving Disabled in South Carolina year over year?

In 2024, funders in South Carolina awarded a total of 24,410 grants.

2022 21,855

2023 21,722

2024 24,410

Top Grant Focus Areas

Among all the Grants for Nonprofits Serving Disabled in South Carolina given out in South Carolina, the most popular focus areas that receive funding are Education, Philanthropy, Voluntarism & Grantmaking Foundations, and Human Services.

1. Education

2. Philanthropy, Voluntarism & Grantmaking Foundations

3. Human Services

Funding Over Time

How is funding for Grants for Nonprofits Serving Disabled in South Carolina changing over time?

Funding has increased by 22.06%.

2022 $1,534,818,247

2023 $1,485,349,233
-3.22%

2024 $1,813,067,383
22.06%

South Carolina Counties That Receive the Most Funding

How does grant funding vary by county?

Greenville County, Richland County, and Charleston County receive the most funding.

County Total Grant Funding in 2024
Greenville County $580,646,902
Richland County $413,417,941
Charleston County $355,724,083
Spartanburg County $325,246,878
Pickens County $159,596,081