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Best Douglas County Grants for Nonprofits in South Dakota

Looking for grants for 501(c)(3) nonprofit organizations working in Douglas County, South Dakota? Find the perfect grant for your nonprofit on Instrumentl.

9,000+

Available grants

$3.26B

Total funding

$5K

Median grant

9,000+ grants
$3.26B total
$5K median

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9,007 Results based on applied filters

Comis Foundation Grant

The Comis Foundation
Private
United States
US $5,000 - US $75,000
The Comis Foundation Grant aims to provide equitable opportunities for children to thrive through education and community engagement. It supports innovative programs that enhance educational outcomes, focusing on areas such as capacity building and pilot projects. With funding ranging from $5,000 to $75,000, the foundation prioritizes nonprofit organizations that foster inclusive environments. By emphasizing trust and collaboration, Comis Foundation strives to create lasting impacts in the communities it serves.
Youth Services Education - Preschool / Early Learning Education - K through 12 +5 more

Mentored Nurse Practitioner/Physician Assistant Award for Workforce Expansion

Rheumatology Research Foundation
Private
United States
US $25,000
The Mentored Nurse Practitioner/Physician Assistant Award for Workforce Expansion, funded by the Rheumatology Research Foundation, aims to increase the number of rheumatology healthcare providers across the U.S. This initiative addresses the growing demand for specialists, particularly in underserved areas. With an award amount of $25,000 for one year, it equips new NP/PAs with essential skills and knowledge needed for successful integration into rheumatology practices, enhancing patient access to quality care.
Musculoskeletal Diseases Arthritis Medical Education & Professional Training

Health Professional Online Education Grant

Rheumatology Research Foundation
Private
United States
US $1,999
The Health Professional Online Education Grant, offered by the Rheumatology Research Foundation, aims to enhance the skills of non-physician rheumatology professionals. By covering registration costs for the Advanced Rheumatology Course, this grant addresses the growing need for knowledgeable healthcare providers in rheumatology, ensuring better patient care for those with rheumatic diseases. This initiative supports the Foundation's mission to cultivate a robust workforce and improve health outcomes for patients.
Musculoskeletal Diseases Arthritis Medical Education & Professional Training

Rheumatology Future Physician Scientist Award

Rheumatology Research Foundation
Private
United States
Up to US $60,000
The Rheumatology Future Physician Scientist Award aims to enhance the research training of promising students pursuing MD or DO degrees, including those in combined programs. This award supports emerging physician-scientists, promoting their investigative careers in rheumatology. Grants of up to $30,000 per year are available for research projects aligned with the Rheumatology Research Foundation's mission, which focuses on improving patient health outcomes in rheumatic diseases.
Musculoskeletal Diseases Arthritis Medical Education & Professional Training

Resident Research Preceptorship

Rheumatology Research Foundation
Private
United States
US $15,000
The Resident Research Preceptorship, funded by the Rheumatology Research Foundation, offers a $15,000 award for a three-month, full-time research experience. This initiative aims to inspire medical residents to explore careers in rheumatology research, enhancing the future workforce. By fostering mentorship and hands-on learning, the program supports the development of skilled rheumatology professionals, ultimately improving patient care for those with rheumatic diseases.
Musculoskeletal Diseases Arthritis Medical Education & Professional Training

Marketing Sponsorships

State Farm Companies Foundation
Corporate
United States
Unspecified amount
State Farm Companies Foundation offers marketing sponsorships to organizations that align with their mission of building safer, stronger communities. They are open to partnerships that enhance their marketing strategies on both local and national levels. Interested parties can expect a review of their proposals within 2-3 weeks. This initiative aims to foster collaboration with various brands and causes that resonate with State Farm's vision.
Community Services

Macy Faculty Scholars Program

Josiah Macy Jr. Foundation
Private
United States
Up to US $125,000
The Macy Faculty Scholars Program, funded by the Josiah Macy Jr. Foundation, supports early-career educators in medicine and nursing, promoting their development as future leaders. Scholars receive substantial financial support, mentorship, and access to educational resources, including funding for professional development activities and participation in a Harvard Macy Institute course. This initiative aims to enhance the educational landscape by nurturing diverse talent in the healthcare education field.
Medical Education & Professional Training Nursing

Blavatnik National Awards for Young Scientists

Blavatnik Family Foundation
Private
United States
US $250,000
The Blavatnik National Awards for Young Scientists honor exceptional faculty-rank scientists and engineers in the U.S. Recognizing achievements in Life Sciences, Physical Sciences & Engineering, and Chemical Sciences, each Laureate receives $250,000 in unrestricted funds. Nominations come from a select group of institutions and previous Laureates, emphasizing innovation and impact. The awards celebrate the future potential of young researchers, fostering diversity in STEM fields. The ceremony takes place annually in New York City.
Science Engineering

Edward Mallinckrodt, Jr. Foundation: Grant

Edward Mallinckrodt Jr Foundation
Private
United States
Up to US $225,000
The Edward Mallinckrodt, Jr. Foundation provides crucial support for early-stage biomedical researchers in the first four years of their tenure-track positions at American institutions. With grants of $75,000 annually for up to three years, this funding aims to help investigators advance their projects towards securing independent funding. The foundation emphasizes the importance of a clear project description and requires a one to two-page lay summary, making it accessible to both scientific and non-scientific board members.
Biology Health & Medicine Science

Parker B. Francis Fellowship for Pulmonary Research

The Francis Family Foundation
Private
Canada, United States
Up to US $225,000
The Parker B. Francis Fellowship for Pulmonary Research offers three years of funding, totaling $225,000, for clinical and basic scientists transitioning to independent research careers in pulmonary and critical care medicine. Eligible candidates include those with relevant doctoral degrees, U.S. or Canadian citizenship, and a track record of research experience. The fellowship encourages diverse research topics, including bioethics in pulmonary medicine, while requiring mentorship and adherence to strict eligibility criteria.
Lung Cancer Respiratory Diseases & Systems

MIND Prize

The Pershing Square Foundation
Private
United States
US $750,000
The MIND Prize, funded by The Pershing Square Foundation, supports innovative research to combat neurodegenerative diseases like Alzheimer's. It empowers early-to-mid-career investigators to explore unconventional approaches and fosters collaboration across disciplines. Each winner receives $250,000 annually for three years, promoting advancements in neuroscience and creating a unique network for researchers. The initiative aims to enhance our understanding of brain health and tackle pressing societal challenges.
Neurological Diseases & Disorders Neuroscience Dementia & Alzheimer’s Disease

Biogen General Grants

Biogen Foundation Inc.
Corporate
United States
Unspecified amount

Biogen General Grants

Funding to support a project or program that does not fit any of the other defined grant categories.

Biosimilars Neurological Diseases & Disorders Musculoskeletal Diseases +2 more

Post-Doctoral Fellowships

American Parkinson Disease Association
Private
United States
Up to US $150,000
The American Parkinson Disease Association offers Post-Doctoral Fellowships to support research focused on Parkinson's disease. These fellowships, lasting two years, provide up to $75,000 per year to eligible post-doctoral trainees at U.S. institutions. Applicants must have completed their MD, PhD, or residency within two years prior to the award. Funding can cover direct research costs, but not travel or publication expenses over $1,000, ensuring resources are allocated effectively for impactful research.
Parkinson’s Disease

Next Gen Pregnancy Initiative Grants

Burroughs Wellcome Fund
Private
Canada, United States
Up to US $500,000
The Burroughs Wellcome Fund's Next Gen Pregnancy Initiative Grants aim to enhance research on pregnancy outcomes, addressing issues such as preterm birth and maternal health. With an emphasis on fostering diverse scientific collaboration, the initiative supports innovative proposals from researchers across various disciplines. Each grant offers up to $500,000 over four years, encouraging groundbreaking studies that explore the biological and environmental factors affecting pregnancy. This initiative seeks to improve health outcomes through informed research and interdisciplinary partnerships.
Maternal And Perinatal Health Health Disparities & Social Determinants of Health

George C. Cotzias, MD, Memorial Fellowship

American Parkinson Disease Association
Private
United States
US $375,000
The George C. Cotzias, MD, Memorial Fellowship, established by the American Parkinson Disease Association, supports young neurologists in their research and treatment of Parkinson's disease and related disorders. Funded at $125,000 annually for three years, this fellowship encourages recent graduates to develop their careers in neurology, ensuring they have the mentorship and resources necessary for success. The fellowship aims to honor Dr. Cotzias' legacy and inspire the next generation of leaders in neurology.
Parkinson’s Disease Neurological Diseases & Disorders

Kaiser Permanente Center for Gun Violence Research and Education Grant Program

Kaiser Permanente Advisory Services
Private
United States
Up to US $300,000
The Kaiser Permanente Center for Gun Violence Research and Education Grant Program aims to transform the landscape of gun violence research and education by funding initiatives that address community firearm violence and suicide. This program focuses on partnering with affected communities, integrating healthcare approaches, and providing substantial funding to enhance research capacity and intervention effectiveness. With funding available in two categories, the initiative seeks to promote evidence-based solutions that foster community healing and well-being.
Gun Violence Prevention Suicide Prevention

Postdoctoral Diversity Enrichment Grant Program

Burroughs Wellcome Fund
Private
Canada, United States
US $60,000
The Postdoctoral Diversity Enrichment Grant Program, funded by the Burroughs Wellcome Fund, offers $60,000 over three years to support underrepresented postdoctoral fellows in the U.S. and Canada. This initiative aims to enhance their career development through mentorship and networking opportunities. Since its inception in 2013, the program has awarded over 150 fellowships, investing more than $9 million to promote diversity in biomedical research and foster an inclusive scientific community.
Diversity, Equity & Inclusion Science Biology +1 more

AGA: Research Scholar Award

American Gastroenterological Association
Association/Society
Canada, Mexico +1 more
US $300,000
The AGA Research Scholar Award offers $100,000 per year for three years to early-career faculty in digestive disease research. Applicants must hold an MD or PhD and be in a full-time faculty position in North America. The award fosters scientific independence by requiring a minimum of 50% research effort. AGA membership is mandatory, and applicants are encouraged to self-assign their proposals to specific research categories. This award aims to support promising junior researchers in their pursuit of independent research careers.
Digestive System Health & Diseases

FNBO Impact Grants

First National Bank of Omaha
Corporate
Colorado, Illinois +5 more
Unspecified amount
The FNBO Impact Grant Program aims to empower nonprofit organizations that eliminate barriers to economic and social opportunities. Focusing on Affordable Housing, Workforce Development, and Financial Literacy, this initiative supports projects that enhance community well-being and promote personal economic self-sufficiency. While the 2025 grant cycle is closed, interested applicants should check back in early 2026 for updates on future funding opportunities.
Equitable & Affordable Housing Community Development & Revitalization Workforce Preparation & Job Readiness +7 more

National Scleroderma Foundation: Pediatric Scleroderma

National Scleroderma Foundation
Private
United States
Up to US $500,000
The National Scleroderma Foundation supports pediatric scleroderma research with up to $500,000 in funding for new and established investigators. Their mission focuses on advancing medical research and promoting awareness of scleroderma, with the vision of improving the lives of those affected. This initiative aims to encourage innovative research that could lead to better treatments and a potential cure for pediatric scleroderma, enhancing support for affected families.
Rare Diseases Immune System Diseases Children’s Health & Pediatrics

Blue Meridian Partners Grant

Blue Meridian Partners Inc
Private
United States
Unspecified amount
Blue Meridian Partners Grant aims to transform lives of young people and families in poverty by investing in scalable strategies that enhance economic and social mobility. The organization seeks stand-alone nonprofits with a proven track record, a compelling vision, and strong leadership. With a commitment to performance-based investing, Blue Meridian provides significant capital, often exceeding $100 million, to foster impactful solutions and address pressing social challenges effectively.
Economic Services & Development Poverty Alleviation & Services Youth Services +3 more

EmpowHer Grants

Boundless Futures Foundation
Private
United States
Up to US $50,000
EmpowHer Grants, offered by the Boundless Futures Foundation, provide essential financial support and resources to female entrepreneurs in the U.S. who are committed to creating social impact through their businesses. Grants, which can go up to $25,000, are available to those with businesses that are less than three years old and demonstrate revenue generation. This initiative aims to empower women by reducing barriers and fostering a supportive entrepreneurial community.
Entrepreneurship Business Development

Corporate Giving Program: Health Equity in Cardiovascular Disease Grant

Cytokinetics
Association/Society
United States
Up to US $20,000
The Corporate Giving Program by Cytokinetics focuses on health equity in cardiovascular disease, targeting underserved communities. It seeks to fund initiatives that address disparities in healthcare access, including public health campaigns, community support programs, and innovative solutions. Eligible organizations must be 501(c)(3) nonprofits in the U.S. that align with these goals, ensuring that no direct healthcare practice involvement occurs. This initiative aims to foster equitable health outcomes and enhance community well-being.
Cardiovascular Diseases & Systems Epidemiology & Public Health

Emily Stover Memorial Scholarship

Community Foundation for Nantucket
Private
United States
US $1,000 - US $10,000
The Emily Stover Memorial Scholarship offers $2,000 annually to support outstanding members of the Nantucket community. This scholarship is aimed at individuals who are dedicated to helping others and are pursuing careers that reflect this commitment. Eligible applicants must be Nantucket residents attending accredited colleges or universities, demonstrating a passion for community service and a desire to make a positive impact.
Academic Scholarship Programs

HEAL Initiative: Pain Research Enhancement Program (PREP) (R15 Clinical Trial Optional)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $375,000
The HEAL Initiative's Pain Research Enhancement Program (PREP) aims to support R15-eligible Principal Investigators in conducting vital pain research. This initiative fosters interdisciplinary partnerships and enhances the research environment for health trainees at eligible institutions. Key application deadlines include November 19, 2024, for standard submissions, with later dates for AIDS-related applications. Engaging students in these projects is a priority to advance pain research effectively.
Chronic / Acute Pain Drug Use Disorder Anesthesia and Pain Medicine

Tribal Undergraduate to Graduate Research Training and Leadership Experiences (TURTLE) Program (UE5/T32)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Tribal Undergraduate to Graduate Research Training and Leadership Experiences (TURTLE) Program aims to foster the development of American Indian and Alaska Native scientists by funding eligible Tribal Entities. This initiative focuses on creating effective training and mentoring activities for individuals pursuing doctoral degrees in biomedical research. Ultimately, it seeks to enhance the capability of researchers to address health disparities within AI/AN communities, ensuring culturally appropriate and ethically responsible research practices.
Indigenous Health Systems Native American Services Medical Education & Professional Training +1 more

Tribal Undergraduate to Graduate Research Training and Leadership Experiences (TURTLE) Program (UE5/T34)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Tribal Undergraduate to Graduate Research Training and Leadership Experiences (TURTLE) Program aims to support federally recognized AI/AN Tribes and organizations in developing a workforce of researchers focused on AI/AN health disparities. This initiative, funded by the NIH, provides phased support for training and mentoring activities that equip individuals with the necessary skills to conduct culturally responsible biomedical research, ultimately guiding them towards successful careers in the biomedical research field.
Indigenous Health Systems Native American Services Biology +2 more

Douglas County Grants for Nonprofits Highlights

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Read more about each grant below or start your 14-day free trial to see all Douglas County grants recommended for your specific programs in South Dakota.

Last updated: November 2, 2026. Next update: December 6, 2026.

Grant Insights : Grant Funding Trends in South Dakota

Average Grant Size

What's the typical amount funded for South Dakota?

Grants are most commonly $110,621.

$110,621

Total Number of Grants

What's the total number of grants in Douglas County Grants for Nonprofits year over year?

In 2024, funders in South Dakota awarded a total of 6,460 grants.

2022 6,268

2023 6,140

2024 6,460

Top Grant Focus Areas

Among all the Douglas County Grants for Nonprofits given out in South Dakota, the most popular focus areas that receive funding are Education, Human Services, and Philanthropy, Voluntarism & Grantmaking Foundations.

1. Education

2. Human Services

3. Philanthropy, Voluntarism & Grantmaking Foundations

Funding Over Time

How is funding for Douglas County Grants for Nonprofits changing over time?

Funding has increased by 17.48%.

2022 $638,830,994

2023 $606,495,212
-5.06%

2024 $712,509,384
17.48%

South Dakota Counties That Receive the Most Funding

How does grant funding vary by county?

Minnehaha County, Lake County, and Pennington County receive the most funding.

County Total Grant Funding in 2024
Minnehaha County $176,653,145
Lake County $117,647,066
Pennington County $90,630,616
Brookings County $75,457,854
Todd County $56,559,538