Best Grants for 501(c)(3) in Florida

The Trans Justice Funding Project (TJFP) provides grants to grassroots trans-led organizations in the U.S. and territories, focusing on those with budgets under $250,000. TJFP supports initiatives that address varying needs within trans communities, including health, legal aid, and mutual aid projects. The organization prioritizes groups led by trans people of color and emphasizes the importance of centering marginalized voices in the fight for trans justice.

The ADDF-Harrington Scholar Program aims to transform academic discoveries into effective treatments for Alzheimer’s disease and related dementias. With funding of up to $600,000 annually, this program prioritizes innovative drug targets and supports research from hit-to-lead optimization to IND-enabling studies. Eligible applicants include academic investigators with a strong potential to advance meaningful therapeutics. The program emphasizes collaboration with industry experts, making it a significant opportunity for advancing dementia research.

The Capacity Building for Global, Regional, and National Immunization Programs aims to enhance immunization efforts in key countries, focusing on the prevention and control of vaccine-preventable diseases like polio and measles. By strengthening immunization services and surveillance systems, the program will better address emerging health threats and reach under-immunized populations. Additionally, it will support sustainable practices through National Immunization Technical Advisory Groups and manage the National Stop Transmission of Polio program in Pakistan.

The North Ottawa Hospital Auxiliary Fund Scholarship, supported by the Grand Haven Area Community Foundation, offers financial assistance to students pursuing medical and healthcare-related degrees. Established in memory of Marjorie Hren Blohm, this scholarship prioritizes applicants from the Tri-Cities area who demonstrate financial need and academic achievement. Applicants must be at least second-year college students accepted into a relevant program, ensuring that qualified candidates receive the support they need to succeed in their educational pursuits.

The CLRA Research Grant Program, led by the Children’s Leukemia Research Association, focuses on funding innovative research aimed at uncovering the causes of leukemia and improving treatment options. Grants totaling $30,000 are awarded to U.S.-based researchers, with the intention of advancing scientific understanding and ultimately finding a cure. The program has made significant contributions to the high cure rates for childhood leukemia, showcasing the importance of continued research in this field.

The Irv and Irene Boersen Scholarship supports students from the Regional Synod of the Great Lakes pursuing a Master of Divinity at Western Theological Seminary. Applicants must demonstrate financial need, maintain a GPA of 3.0 or higher, and submit a FAFSA summary page. This renewable scholarship aims to cultivate future pastors and is awarded based on recommendations. It promotes educational access and community involvement, fostering a thriving environment in the Holland/Zeeland area.

The Autism Speaks Predoctoral Fellowship aims to support early career autistic scientists in their research endeavors. By providing a two-year fellowship that includes a $40,000 annual award, the program seeks to enhance research training opportunities for promising candidates. Fellows will collaborate with leading mentors in autism research, ensuring that individuals with both academic expertise and lived experience can significantly contribute to advancements in the field. This initiative underscores Autism Speaks' commitment to fostering inclusivity and innovation in autism research.

The NIMH Career Transition Award (K22) supports tenure-track intramural investigators at NIMH in their transition to independent research faculty positions. This program aims to foster innovative research in mental health, encouraging applicants with a strong record of research excellence. Key deadlines for applications vary, including those for standard and renewal submissions, emphasizing the importance of timely applications to secure funding and advance mental health research initiatives.

This initiative aims to support research interventions targeting disparities in liver diseases and liver cancer among underserved populations in the U.S. It encourages innovative approaches to reduce health inequities and improve health outcomes. The funding opportunity is available through various deadlines for both standard and renewal applications, promoting multi-level strategies to address these critical health issues effectively.

Community Finance Initiative 

Advancing the financial resilience of low-income households across the U.S.

This model enables us to engage and support a broad range of organizations across the globe to tackle some of the most pressing social issues of our time.

The Citi Foundation’s 2026 Community Finance Initiative commits $35 million to support programming that bolsters the financial stability, strength and safety of low-income households in the U.S.

Focus Areas

The Foundation seeks to support organizations advancing low-income household financial resilience in the United States across three focus areas:

Stabilize: Programs that help low-income households to build financial skills and confidence to manage daily finances and navigate financial stress.

• Financial coaching on budgeting, credit, debt reduction and savings strategies.
• Digital tools offering personalized financial guidance and product navigation.
• Assistance with public benefits and social safety net programs.

Strengthen: Programs that help low-income households build and repair credit, as well as short- and long-term financial assets.

• Financial products or services for credit building and credit repair.
• Initiatives to increase savings, including emergency funds.
• Support for homeownership, including readiness, preservation and long-term stability (e.g., first-time buyer assistance, preventing displacement and support systems for aging in place resources).

Safeguard: Programs that protect low-income household financial security by preventing and addressing financial losses.

• Education and support for the safe and confident use of digital financial tools.
• Fraud and scam awareness, prevention and recovery initiatives, including protection from identity theft.
• Interventions to help households recover from major financial shocks (e.g., healthcare costs, extended family care, job transitions or natural disasters).

Funding Opportunity

The Foundation plans to award 70 $500,000 (USD) grants (to be disbursed over two years) totaling $35 million to community organizations working in select communities where Citi has a presence.

The grants will be restricted and are anticipated to be disbursed in two annual payments in 2026 and 2027. Proposed projects should be for a term of 24 months, starting no sooner than August 1, 2026 and ending no later than December 31, 2028.

The Pediatric Cancer Research Foundation (PCRF) is dedicated to funding innovative research aimed at curing childhood cancer. With a focus on collaborative efforts, PCRF has contributed over $51 million since 1982, significantly improving survival rates for childhood cancers. The Translational Research Grant supports cutting-edge clinical trials and therapeutic approaches, enhancing the journey from laboratory discoveries to patient care. This initiative underscores the urgent need for effective treatments, offering hope for children diagnosed with cancer and their families.

The Pediatric Cancer Research Foundation (PCRF) offers the Emerging Investigator Fellowship Grant to support post-doctoral fellowships and clinical investigator training for promising pediatric cancer researchers. This grant aims to accelerate advancements in childhood cancer treatment by funding innovative research ideas. Applicants must have completed a minimum of two years in their fellowship or be within two years of their junior faculty role. This initiative fosters the next generation of researchers dedicated to combating childhood cancer.

The NCAA Jim McKay Graduate Scholarship honors the legacy of journalist Jim McKay by awarding a one-time $10,000 scholarship to one male and one female student-athlete annually. Eligible candidates must have a minimum GPA of 3.5, demonstrate integrity, and show interest in sports communication. There is no limit to the number of nominations from institutions, highlighting the NCAA's commitment to supporting student-athletes in their academic and professional pursuits.

The Pediatric Cancer Research Foundation (PCRF) offers Donor Designated Grant Programs aimed at funding innovative projects addressing childhood cancer. These grants support researchers dedicated to finding cures, enhancing treatment, and improving care. With an annual commitment to extraordinary researchers, PCRF ensures funds are directed towards promising advances in prevention and treatment. Since 1982, PCRF has raised over $51 million, significantly impacting survival rates and striving to eliminate childhood cancer through collaborative efforts and cutting-edge research.

Community Foundation of Henderson County

Community Foundation of Henderson County was incorporated in 1982 by a group of fourteen dedicated and compassionate local leaders with the immediate need to manage two funds - the William C. Armstrong Scholarship Fund and the Charlie Renfrow Scholarship Fund, in addition to providing a permanent vehicle for citizens to give back to their community.

Our Mission is to help people who care make lasting contributions to causes that matter. The Community Foundation of Henderson County is a highly visible, philanthropic leader directed by an engaged and committed board, staffed by qualified employees, empowering donors at all levels to invest in professionally managed charitable funds that address community needs.

Bryce A. Malsbary (BAM) Scholarship

The purpose of the Fund is to provide a scholarship for a person seeking higher education at an accredited institution, including but not limited to: vocational, technical, trade, college, or university levels of education. Assistance is for a resident of Henderson County or Polk County, North Carolina, leading to a degree. Candidate must show financial need, GPA 3.0 or higher, and have community service, work, or school activities. Student must be a legal resident of North Carolina.

The NCCIH Natural Product Early Phase Clinical Trial Phased Innovation Award (R61/R33) invites research proposals for early phase clinical trials of natural products, including botanicals and dietary supplements, emphasizing scientific validity for further testing. Applicants may receive up to three years of funding for pharmacokinetics and bioavailability studies, with potential for an additional three years to evaluate clinical outcomes. This initiative aims to optimize natural product delivery through innovative study designs.

Community Foundation for Mason County, MI

At the Community Foundation for Mason County, we work with donors, grantees, and advisors to address key community issues. As a leader in community philanthropy, building a vibrant community with great opportunities for all, we are focused on advancing education, increasing recreation opportunities, and community and economic development.

The mission of the Community Foundation is to engage donors and connect them with opportunities to make a lasting impact, build community endowment, provide leadership on key issues, and make grants that reflect the communities we serve.

Merry E. Petersen Memorial Scholarship

This scholarship has been made possible by the generosity of Frank Petersen, who established the Merry E. Petersen Memorial Scholarship of the Community Foundation for Mason County.

The Merry E. Petersen Memorial Scholarship was founded on the belief that persons wishing to serve others in the benevolent field of nursing should be given the chance to achieve it. Merry graduated with honors from St. Francis School of Nursing in Illinois. During her lifetime, she was devoted to the nurturing care of others, and her family wanted to encourage others to pursue this important profession.

Cumberland Community Foundation ("CCF") manages more than 60 scholarship endowment funds created by local individuals, families, civic organizations, and corporations who want to provide a path to higher education for future generations. 

Each year, Cumberland Community Foundation announces more than $1,000,000 in college scholarships to students from southeastern North Carolina.

Cooney-Wilderman Leadership Scholarship

Graduating senior from Cumberland County Schools (public School system) Cumberland County, NC.

The Bay Area Lyme Foundation's Emerging Leader Award supports innovative research in Lyme disease, offering two $150,000 grants to post-doctoral and early-career scientists. Applicants are encouraged to propose proof-of-concept projects that enhance diagnostics or therapeutics. The award seeks to attract talent and foster scientific leadership in biomedical sciences. Evaluation criteria include the potential for novel therapies, scientific rationale, and support from institutions. This opportunity is ideal for those new to tickborne disease research.

The Celiac Disease Foundation offers the Jocelyn Silvester Rising Villus Student Research Award to encourage medical students and residents to pursue celiac disease research. This prestigious award provides a $5,000 stipend for a 10-week mentored research experience across North America, honoring Dr. Jocelyn Silvester's contributions to the field. Recipients must secure a mentor and maintain good standing in their academic programs, ensuring a commitment to advancing celiac disease research.

This funding opportunity invites applications for R01 grants focused on molecular imaging methods to explore cancer inflammation in vivo. It aims to enhance understanding of dynamic interactions between inflammation and cancer through innovative imaging techniques. The initiative encourages collaborations between cancer researchers and imaging scientists to leverage molecular imaging for identifying cellular physiology changes in response to treatment. Deadline dates for applications range from February 2025 to October 2027, emphasizing timely submission for prospective researchers.

The Integration of Imaging and Fluid-Based Tumor Monitoring in Cancer Therapy (R01 Clinical Trial Optional) aims to enhance cancer treatment by integrating imaging and liquid biopsy assays. This initiative, led by the National Cancer Institute (NCI), encourages grant applications focused on assessing therapy responses and resistance emergence in patients. Key deadlines for submissions span from February 2025 to January 2028, providing ample opportunities for researchers to contribute to this vital area of cancer research.

The National Multiple Sclerosis Society offers Career Transition Fellowships aimed at fostering young scientists in MS research. This program supports postdoctoral trainees with a doctoral degree and exceptional potential, providing funding for advanced training and faculty support over five years. Applicants must demonstrate relevance to high-priority research questions outlined in the Society's Pathways to Cures Roadmap, which focuses on stopping MS, restoring function, and ending the disease through prevention.

The National Multiple Sclerosis Society offers Postdoctoral Fellowships to support innovative research aimed at advancing the understanding and treatment of multiple sclerosis. These fellowships are designed for promising researchers holding advanced degrees, providing funding for training that enhances their ability to conduct impactful studies. The Society prioritizes applications that align with high-priority research questions outlined in its Pathways to Cures Roadmap, emphasizing the importance of diverse methodologies and engagement with underserved populations.

Community Foundation for Mason County, MI

At the Community Foundation for Mason County, we work with donors, grantees, and advisors to address key community issues. As a leader in community philanthropy, building a vibrant community with great opportunities for all, we are focused on advancing education, increasing recreation opportunities, and community and economic development.

The mission of the Community Foundation is to engage donors and connect them with opportunities to make a lasting impact, build community endowment, provide leadership on key issues, and make grants that reflect the communities we serve.

Rick Chapman Legacy League Scholarship

This scholarship has been made possible by the generosity of the Rick Chapman Legacy League, created in memory of Rick, a beloved local entrepreneur who owned and operated Chuck Wagon Pizza in Ludington, Michigan, for many years.

Inspired by Rick's own path of starting his business at a young age, the scholarship supports students who are pursuing business education and entrepreneurship with the hope that recipients will eventually live and work in Mason County. The scholarship fund is administered by the Rick Chapman Legacy League Board, composed of Rick's high school friends who would visit Rick at Chuck Wagon when in town, longtime customers and neighbors from the community, and an overall eclectic mix of people from different walks of life that Rick welcomed. The board and several other Rick Chapman friends and fans host an annual golf outing near Rick's birthday in August to raise money for scholarships. Entry fees, sponsorships, and a silent auction contribute to the scholarship fund. The Rick Chapman Legacy League Scholarship honors Rick’s memory and commitment to fostering entrepreneurship. By investing in local students, the Legacy League hopes to inspire students to follow in Rick's footsteps, contributing to the vibrancy of the Mason County community.

Opera Grants for Women Composers: Discovery Grants support the creation of new operas by women composers, promoting gender parity and diversity in the field. These grants assist composers in exploring opera as an art form, funding activities like libretto readings and workshops. OPERA America is committed to enhancing the operatic repertoire with diverse perspectives, and these grants are made possible through the support of the Virginia B. Toulmin Foundation.

Community Foundation for Mason County, MI

At the Community Foundation for Mason County, we work with donors, grantees, and advisors to address key community issues. As a leader in community philanthropy, building a vibrant community with great opportunities for all, we are focused on advancing education, increasing recreation opportunities, and community and economic development.

The mission of the Community Foundation is to engage donors and connect them with opportunities to make a lasting impact, build community endowment, provide leadership on key issues, and make grants that reflect the communities we serve.

Rick & Mary Ann Randall Scholarship

This scholarship has been made possible by the generosity of Rick and Mary Ann Randall, who established the Rick and Mary Ann Randall Scholarship of the Community Foundation for Mason County.

As quoted by Rick and Mary Ann Randall..."We value education and the opportunities it provides. We believe that all students who wish to pursue higher education should be able to do so, regardless of their academic standing or financial resources. Therefore, we offer scholarships to deserving students who demonstrate a strong desire to continue their education beyond high school."