Best Large Grants for Nonprofit Organizations in Florida

Debartolo Family Foundation

The Debartolo Family Foundation was founded in 2001 with one goal in mind: To channel the same level of care, compassion and dedication that has allowed the DeBartolo family to find success in real estate, sports, and other ventures, into efforts that help serve the underserved communities of Tampa Bay.

For nearly two decades, we have strengthened the community by helping youth, veterans, animals, and local grassroots organizations that share our mission and values. The Foundation annually awards scholarships to students, provides back to school grants to local teachers, adopts Bay Area families during the holidays, and three times each year presents the Spirit of Humanity Award – a $25,000 donation that honors the most outstanding local philanthropic outreach programs. Since 2002, the DeBartolo Family Foundation has given nearly $17 million to strengthen Tampa Bay by bringing people together through its passion for giving back.

Spirit of Humanity Award

The DeBartolo Family Foundation’s Spirit of Humanity Award honors local nonprofit organizations that impact the Tampa Bay community in a meaningful way. Recipients of this award create unity, demonstrate hard work, and extend their outreach by helping people in need to overcome obstacles that are beyond their control. Since 2002, 60+ recipients have been recognized with the $25,000 Spirit of Humanity Award, awarded three times annually.

If you believe your organization, or an organization that you support, would be a candidate for this award, please submit the nomination form. 

American Psychiatric Association Foundation

There is no health without mental health. The APA Foundation is working in your community to provide the support and resources we all need to prioritize mental wellbeing where you live, learn, work, worship, and play.

Backed by the medical expertise of the APA and industry-leading strategic partners, we administer community-changing programs, public education campaigns, grants, and awards aimed at increasing mental health literacy, connecting individuals to needed care, and shifting attitudes toward mental health.

Edwin Valdiserri Correctional Public Psychiatry Fellowship

The Edwin V. Valdiserri Correctional Public Psychiatry Fellowship program has been made possible by a generous gift from Ronald Valdiserri, M.D., M.P.H., in memory of his brother Edwin V. Valdiserri, M.D. and creates a special opportunity for current residents who are interested in public, community, or forensic psychiatry programs to receive additional experience, training and mentorship in a correctional setting.

Program Benefits

• Sponsorship to attend a minimum of four APA meetings: Two APA Annual Meetings and Two Fellowship Forums
• Attend Fellows' choice of one of the following: The American Academy of Psychiatry and the Law (AAPL) Annual Meeting OR National Commission on Correctional Health Care (NCCHC) Annual Conference
• Attend courses and workshops at APA meetings and be exposed to training opportunities that develop leaders in public psychiatry
• Collaborate with other Public Psychiatry Fellows to plan a workshop at the APA meeting
• Gain an understanding of APA/APAF governance through service on an APA Council, Committee, or APAF initiative
• Have the opportunity to sit on the APA Board of Trustees as a non-voting member (one of the Edwin Valdiserri/Public Psychiatry Fellows allowed)
• Cultivate a professional network with psychiatrists through exclusive events and engagements with APA leaders. Establish relationships and peer-mentorship with a diverse group of resident fellows with similar career interests and goals

Program Expectations

• Maintain APA membership and good standing in one’s residency program throughout the fellowship
• Contribute a minimum of 40 volunteer hours annually in a correctional facility
• Provide confirmation from your Training Director or Department Chair that this required volunteer service is feasible and can/will be supported
• Attend two consecutive APA Meetings, two Fellowship Forums, and all fellowship related activities
• Actively participate on an assigned APA Council, Committee, or APAF work group
• Participate in Fellowship teleconferences (a minimum of 50%)
• Participate in mid-year and year-end evaluations with Fellowship Program Manager.

The Cognitive Neuroscience (CogNeuro) Program by the National Science Foundation aims to fund proposals that deepen our understanding of the neural mechanisms of cognition and behavior. Successful applications will connect physiology, cognition, and behavior while also promoting outreach and mentoring within the field. Research topics include action, perception, memory, and decision-making. The program encourages broader impacts such as STEM outreach and public engagement in research, with a focus on diverse communities.

The MPS Astronomical Sciences Research Programs, funded by the National Science Foundation, support innovative research in astronomical sciences. These initiatives aim to enhance our understanding of the universe through core research, technological advancements, and instrumentation. Topics include solar storm prediction, the discovery of exoplanets, and the study of black holes. Proposals should reflect ambitious, transformative ideas that may not require immediate practical outcomes, fostering long-term scientific exploration.

The National Science Foundation's Engineering Directorate (NSF ENG) promotes groundbreaking research in chemical, bioengineering, energy, and transport systems. Key programs include Chemical Process Systems, Engineering Biological and Biomedical Systems, Energy, Water, and Resource Engineering, and Transport Phenomena. NSF ENG seeks innovative, transformative proposals that push the boundaries of foundational research, regardless of immediate commercial applications, and emphasizes diverse funding opportunities based on availability.

The Dermatology Foundation offers a Research Grant of $25,000 annually to support innovative projects in dermatology and cutaneous biology. This funding is aimed at junior investigators in the early stages of their academic careers who demonstrate a strong commitment to skin research. Eligible applicants must conduct research within ACGME-approved departments in the U.S. and must not have received funding from other sources for the same project.

The Major Events' Grant, offered by the Miami Beach Visitor and Convention Authority, supports innovative events that enhance tourism and local businesses. Eligible events must demonstrate potential for recurring impact, with criteria including confirmed hotel room nights and media impressions. This initiative aims to elevate Miami Beach's profile as a premier destination, fostering a vibrant cultural landscape while bolstering the local economy and hospitality sector.

The Foundation for Financial Planning provides grants to nonprofit organizations that connect volunteer financial planners with underserved individuals in need of financial guidance. Focused on scalable and sustainable programs, the grants support both established and new initiatives that foster one-on-one relationships between planners and clients. Eligible applicants must be U.S.-based 501(c)(3) nonprofits and engage Certified Financial Planner professionals to ensure quality advice is accessible to those facing financial crises.

About Association of Legal Writing Directors (ALWD) ALWD supports its members’ professional development as teachers, scholars, and leaders through both teaching and scholarship grants. These grants provide funding for legal writing professionals to pursue their scholarly interests and to develop innovative teaching materials. In funding grants, ALWD focuses on providing resources to those who do not have other sources of funding for these endeavors.

ALWD also supports projects that preserve the history of ALWD, honor community contributions, and make ALWD’s history accessible to scholars, teachers, and practitioners into the future.ALWD Teaching GrantsIn furtherance of ALWD’s commitment to the professional development of legal research and writing faculty, ALWD funds annual teaching grants that allow legal writing faculty to spend their summers exploring innovative teaching ideas and producing teaching tools, materials, and curriculum that will assist others in the field. 

Who is Stand Together?

Stand Together is a philanthropic community that helps America’s boldest changemakers tackle the root causes of our country’s biggest problems, from education to the economy, broken communities, and toxic division, among dozens of other pressing issues. We provide our partners with access to resources including funding, a unique network of peers, and a playbook for applying proven principles to transform lives and society.

Foreign Policy Grants

A government’s most important task is to secure the rights and liberties of its citizens—in part, by providing for the common defense. For this reason, the United States should maintain a strong military to keep America safe, prosperous, and free.

In recent decades, the United States has pursued an approach to foreign policy known as primacy or liberal hegemony. This foreign policy has required active and aggressive U.S. military engagement around the globe that has undermined our safety and imperiled our prosperity and liberties.

The Trust supports scholars and institutions interested in challenging the current approach, providing alternative visions for U.S. foreign policy, and engaging in research that can bridge the gap between ideas and policy. The Trust is especially interested in foreign policy research projects from political science, international relations, history, or economics. However, proposals from all fields will be considered on their merits.

Grant Info

We are especially interested in research that:

• Explores topics and issues related to a grand strategy of restraint.
• Examines the role of values and ethics in the formulation of U.S. foreign policy.
• Addresses the unintended consequences of U.S. military actions abroad and explores the costs and impact of engagements in Afghanistan, Iraq, Somalia, Syria, Yemen, and other places where significant counterterrorism efforts have been conducted.
• Considers the impact of U.S. military engagement abroad on American society—for instance, the effect of our foreign policy decisions on civil liberties or the health and welfare of veterans.
• Explores the concept of threat inflation and problematizes theories of credibility and reputation in relation to U.S. foreign policy.
• Analyzes executive–legislative relations in foreign policy, including the constitutional division of war powers.
• Examines the impact of domestic interest groups, businesses, think tanks, and the permanent national security bureaucracy on U.S. foreign policy.
• Explores the growth of the intelligence and national security establishments since 9/11.
• Surveys the costs, risks, and impacts of foreign aid and alliance commitments.
• Studies the costs and benefits of burden-sharing and burden-shifting with current allies.
• Scrutinizes Pentagon spending, force structure, and the strategic demands of U.S. defense policy—including structural incentives for military expenditures.
• Considers the consequences of an increasingly multipolar world, especially as concerns principal geostrategic regions (e.g., Europe, the Middle East and North Africa, and the Western Pacific).
• Explores how changes in technology (such as A2/AD) that impact the offense-defense balance can be leveraged to support a sound approach to grand strategy.

Grant Criteria

Please submit a brief of no more than 3 pages that details the scope of the project. We are open to any type of project: papers, communications campaigns, conferences and convenings, school tours, and much more (we welcome creative ideas).

Funding

Funding levels are commensurate with the requirements of the research and the potential for the research to advance an understanding of critical issues. Accepted proposals may also receive support to disseminate the research findings.

The Traditional Fine Arts Organization Grant aims to support art museums and cultural centers in promoting American representational art through co-sponsorship of exhibitions. The grant encourages institutions to provide detailed information about their exhibitions online and to make catalogs freely available. Grants are available for exhibits opening through mid-2025, fostering education and appreciation of art while avoiding funding for capital improvements or operating expenses.

The Home Visiting Research, Improvement, Sustainability and Evaluation Center (HV-RISE) aims to enhance home visiting services for families. By leveraging research, HV-RISE supports programs in testing and implementing effective practices, thereby improving outcomes. This initiative seeks to identify and expand successful strategies, ensuring that families receive the best support possible through evidence-based home visiting services.

The Healthy Tomorrows Partnership for Children Program (HTPCP) aims to enhance access to essential preventive clinical and public health services for children through community-driven initiatives. Funded by the US HHS: Health Resources & Services Administration (HRSA), this program focuses on empowering local communities to implement effective strategies that improve children's health outcomes and promote overall well-being. Projects funded under this initiative will play a vital role in ensuring healthier futures for children.

About

Patient Advocate Foundation provides financial assistance to help patients afford treatment and cost of living needs, personalized case management to navigate complex healthcare and social needs challenges, and a wide array of resources to empower people to take charge of their health. Since our founding in 1996—and joining forces with the PAN Foundation in 2026—we have helped 3.8 million patients navigate and access care, granted over $7 billion in financial assistance, served 350,000 people through personalized case management and elevated the patient’s voice to drive improvements in the healthcare system.

Rett Syndrome (RS) Fund

Help with healthcare costs for Rett syndrome.

This TotalAssist fund helps you pay for out-of-pocket healthcare costs, including medication copays, coinsurance, and deductibles, health insurance premiums, and other expenses. Check your eligibility with our quick and easy tools below. If this fund is open, apply today for an instant approval decision and use your grant funding right away

About the disease

Rett syndrome (RS or RTT) is a rare, genetic neurological disorder that causes a loss of motor and spoken language skills, as well as other physical and neurologic impairments early in life.

Diagnosis codes

F84.2

The OTA Resident Research Grant supports resident-led clinical, translational, or basic research projects aimed at improving orthopaedic trauma care. With a maximum funding of $20,000 for a 12-month period, it encourages innovation and research within North America. Eligible applicants must be orthopaedic residents, ensuring that the projects are driven by their unique perspectives and needs. This initiative promotes diversity and aims to enhance the quality of patient care through education and research.

The Primary Biliary Cholangitis (PBC) Fund, established by the Patient Advocate Foundation, offers vital financial assistance to patients managing the costs of treatment for primary biliary cholangitis. This fund covers out-of-pocket healthcare expenses such as medication copays and health insurance premiums, enabling individuals to access necessary treatments. Since its inception, the foundation has empowered millions by providing personalized support and resources, aiming to improve patient care and health outcomes.

The Pompe Disease Health Equity Fund, supported by the Patient Advocate Foundation, offers crucial financial assistance to patients diagnosed with Pompe disease. This fund helps cover out-of-pocket healthcare costs, including medication copays and health insurance premiums. Eligibility requires a confirmed diagnosis and treatment plan, along with meeting specific income criteria. With a mission to enhance health equity, the fund empowers patients to access necessary care and improve their quality of life.

The OTA Member Full Research Grant, offered by the Orthopaedic Trauma Association, aims to fund clinical, translational, or basic research projects related to musculoskeletal trauma. Grants of up to $40,000 per year for two years are available for clinical research, and $25,000 per year for two years for basic research. Eligible applicants include OTA members in good standing, and research must be conducted in North America. The initiative seeks to enhance the quality of care for injured patients.

The Pompe Disease Fund, supported by the Patient Advocate Foundation, offers vital financial assistance to individuals diagnosed with Pompe disease. This fund covers out-of-pocket healthcare costs including medication copays and health insurance premiums. Eligible patients must have a confirmed diagnosis and be receiving treatment or planning to start within 60 days. With over 3.8 million patients helped since its inception, the fund aims to alleviate financial burdens and enhance access to necessary treatments.

The AHNS Endocrine Surgery Section ThyCa Research Grant offers $10,000 for one year to support innovative research projects focused on thyroid cancer. Eligible candidates include U.S. or Canadian AHNS members, including medical students and faculty. Proposals should advance understanding of thyroid cancer's diagnosis, prevention, and treatment. Preference is given to early-stage investigators or those pursuing new inquiries. Applications require letters of support and a detailed budget, with funding limitations on indirect costs.

The Prevention of Musculoskeletal Youth Sports Injuries Grant provides essential funding for new investigators focused on clinical and social research aimed at reducing youth sports injuries. This initiative emphasizes the importance of clinical relevance in project proposals, ensuring that outcomes are practical and applicable. Only one grant will be awarded per institution each year, supporting innovative approaches to enhance youth sports safety and health.

PLTW Launch offers a rolling grant for schools across the U.S. to implement the PLTW Launch program for the upcoming academic year. All schools, especially those serving low-income and minority populations, are encouraged to apply. The grant covers participation and training fees, with requirements to implement multiple PLTW modules over time. This initiative aims to enhance STEM education, ensuring diverse access to innovative learning opportunities.

The Combined Pilot Research Grants program, supported by the Plastic Surgery Foundation and various surgical organizations, aims to promote innovative research in hand and plastic surgery. With funding of up to $10,000 for one-year pilot projects, this initiative encourages the development of surgeon scientists and seeks to enhance research funding in the field. Eligible applicants must be medical professionals holding relevant positions in U.S. or Canadian institutions.

The LAM Foundation offers Pilot and Feasibility Research Awards aimed at fostering innovative research in lymphangioleiomyomatosis (LAM). These awards support hypothesis-driven studies with the potential to advance understanding and treatment options for this rare disease. Applicants can request a maximum of $50,000 for a period of up to one year. The Foundation prioritizes new researchers, encouraging fresh perspectives in LAM research to enhance patient care and ultimately achieve a future without LAM.

The Step Into Swim initiative aims to increase swimming participation among underserved communities by providing learn-to-swim programs. With over 300,000 swim lessons delivered, the program partners with various organizations to ensure children learn vital water safety skills. Funding is strictly for swim lessons, with a focus on developing safe swimmers who understand essential safety rules. Grants will prioritize facilities with certified pool operators, ensuring quality instruction and community engagement in aquatic activities.

The John and Marlene Heslip Architecture Student Scholarship Program supports full-time undergraduate and graduate architecture students at accredited institutions in the U.S. and Canada. With a focus on innovative design using manufactured concrete masonry and hardscape products, the program awards a $5,000 scholarship each academic year. The scholarship aims to advance the education of future architects while fostering a commitment to excellence and diversity in the field.

The NIOSH Centers of Excellence for Total Worker Health® (U19) aims to enhance worker well-being by funding research and translation activities that address harmful exposures and improve working conditions. Priority areas include high-risk occupations, young workers, and chronic diseases. The initiative emphasizes strong project coordination, scientific rigor, and economic evaluations. Projects must utilize the NIOSH Worker Well-Being Questionnaire and share findings with the HERO Clearinghouse, fostering innovative solutions for employers and workers.