Best Large Grants for Nonprofit Organizations in Florida

The Michigan Animal Health Foundation offers research and education grants to enhance animal health and welfare. Since 1977, these grants have supported nearly 50 projects aimed at improving veterinary care and medical techniques. Eligibility varies, with specific criteria for research grants, while educational grants have no restrictions. Researchers and educators alike can benefit from this funding, which plays a vital role in advancing animal health initiatives.

The Toshiba America Foundation offers grants of $5,000 or more to support innovative STEM projects for grades 6-12 in public and nonprofit private schools across the U.S. These grants encourage teachers to implement project-based learning in their classrooms. Founded in 1990, the foundation aims to enhance STEM education by providing necessary resources and support for educators to inspire their students. Applications require school official endorsement and must focus on innovative teaching methods.

Who We Are

The Community Foundation of Central Illinois will make a sustainable philanthropic impact in our community through visible leadership in connecting people who care with causes that matter.

Sue Aplington Kreutz Scholarship Fund

This scholarship fund was established in 2020 to support first-year college students accepted into a four-year college or university.

The Limited Competition for High Impact Specialized Innovation Programs aims to enhance clinical and translational science by funding unique capabilities and addressing critical gaps through the Clinical and Translational Science Award (CTSA) Program. This initiative fosters collaboration across a national network of academic medical centers, facilitating the transition of scientific discoveries into impactful health interventions. Applications are peer-reviewed, ensuring funding is directed towards the most promising proposals.

The Albert H & Jane D Nahmad Foundation provides project-based grants to organizations focusing on youth and education in Miami-Dade County. They support innovative initiatives that aim to create a positive impact in the community. Grants are awarded on a rolling basis, with a focus on thoughtful projects that align with their mission. Eligible applicants must propose project-based initiatives, while annual funds and capital campaigns are not supported.

The ACTA Apprenticeship Program has been supporting California's cultural traditions for nearly 25 years by providing $5,000 contracts to mentor artists for intensive training of eligible apprentices. This program fosters the continuity of traditional arts through one-on-one mentorship, culminating in public presentations and documentation of the learning process. Eligible applicants must submit a collaborative application, demonstrating commitment and quality in their respective art forms. This initiative not only preserves cultural practices but also enhances community engagement.

The Somatic Mosaicism across Human Tissues (SMaHT) Program aims to enhance our understanding of somatic mutations and their impact on human biology and disease. This initiative will establish a Tissue Procurement Center (TPC) to collect and provide clinically relevant tissue samples from a diverse set of healthy donors. The TPC will support ongoing research by ensuring high-quality, well-characterized specimens are available for functional analyses, advancing the field of somatic mosaicism.

The AJ Muste Foundation's Rapid Response Grants support U.S.-based organizations engaged in grassroots activism for social justice. These grants, up to $5,000, are aimed at addressing immediate needs of groups fighting for equality and liberation. The funding is designed for unexpected opportunities and emergencies, promoting powerful organizing efforts. The foundation prioritizes groups lacking traditional funding sources and those focused on systemic change rather than individual support.

VCA Charities is dedicated to enhancing pet ownership by offering Disaster Relief Grants to support animal welfare organizations impacted by natural disasters. These grants provide funding for essential veterinary care, pet supplies, temporary shelter, and transportation costs for rescued animals. Prioritizing immediate relief, VCA Charities also assesses preparedness requests at year-end. The program aims to alleviate the suffering of pets and ensure they remain in loving homes during crises, addressing both urgent and long-term needs in affected communities.

The Somatic Mosaicism across Human Tissues (SMaHT) Program aims to uncover biological processes and disease mechanisms influenced by somatic mutations. Since its inception in 2023, it has produced valuable multi-omic datasets from diverse human tissues. The upcoming Stage 2 Genome Characterization Centers will focus on understanding the impact of these mutations in both healthy and clinically significant samples, enhancing our knowledge of somatic mosaicism's role in human health and disease.

The Hardin County Principal Organization Scholarship, offered by the Central Kentucky Community Foundation, aims to support graduating seniors from Hardin County Schools who plan to pursue a career in education. Applicants must maintain a cumulative GPA of 3.0 or higher. This scholarship serves as a stepping stone for future educators, ensuring they have the financial resources to achieve their academic goals and contribute positively to their communities.

This funding opportunity from the NIH encourages groundbreaking research to enhance, develop, and preserve animal models and related biological materials for studies impacting human health. The program seeks innovative methodologies that can improve the diagnosis and management of diseases affecting animal use in biomedical research. Projects must demonstrate relevance across multiple NIH Institutes to align with broader research goals, emphasizing diverse body systems and disease categories.

The Two-Year College Biology Teaching Award, sponsored by the National Association of Biology Teachers (NABT), recognizes outstanding biology educators in two-year colleges who implement innovative teaching techniques. This award highlights the importance of culturally responsive pedagogies that foster equity and inclusion in various learning environments. Recipients receive a $500 travel honorarium, a recognition plaque, and one year of complimentary NABT membership, supporting their professional development and commitment to enhancing biology education.

The Edward and Wanda Jordan Family Foundation Grant aims to support education, scientific research, and spiritual ministries through voluntary grants. Focused on enhancing the welfare and quality of life for children and youth, this foundation perpetuates the charitable intentions of the Jordan family. Eligible applicants include 501(c)(3) non-profit organizations that align with these values and objectives, ensuring impactful contributions to the community.

The Alpha Foundation Grant, established in 1997, focuses on enhancing the human condition by supporting educational, scientific, and charitable organizations. With a strong emphasis on biotechnology, the foundation aims to aid in disease discovery and cure. Eligible applicants must be tax-exempt 501(c)(3) organizations, primarily operating in Madison County, Alabama. The foundation does not fund individuals or political activities, ensuring its resources directly benefit public charities.

Society of Teachers of Family Medicine (STFM) 

Founded in 1967, the Society of Teachers of Family Medicine (STFM) is a national community of academic leaders committed to developing an accomplished family medicine workforce, prepared to serve as the foundation of America’s health care system. Our members include physicians, PAs, nurse practitioners, behavioral health specialists, researchers, pharmacists, nurses and other health care professionals, health system executives, administrators, coordinators, fellows, residents, students, and others involved in the education of family physicians. 

STFM Advocacy Scholarship for New Faculty

The STFM Advocacy Scholarship for New Faculty provides the opportunity for faculty to attend the Family Medicine Advocacy Summit in Washington, DC, and develop advocacy skills to impact their patient communities. STFM supports up to five scholarships annually. Advocacy makes a real difference for patients and for family medicine. STFM supports five scholarships annually for new faculty to attend the Family Medicine Advocacy Summit in Washington, DC. The next summit will take place in June 2026, providing an opportunity for participants to develop advocacy skills for personal and academic career growth.

The NIH is set to release a funding opportunity for pragmatic and implementation trials aimed at evaluating the effectiveness of interventions in real-world healthcare settings. This initiative encourages collaborations across various health systems to assess the effectiveness and feasibility of interventions. By focusing on commonly encountered conditions in everyday clinical care, the trials aim to provide actionable insights for patients, clinicians, and policymakers. Interested investigators are encouraged to start developing their project proposals.

The Fund for UU Social Responsibility Grant supports Unitarian Universalist organizations in the U.S., Canada, and Mexico, focusing on social justice, community engagement, and fostering generosity. With backing from the Unitarian Universalist Association, the program encourages innovative projects that promote the values of Unitarian Universalism while enhancing community involvement. Grants are typically for one year, with potential for renewal based on project success and community impact.

The Arthur S. Tuttle Fellowship, established in 1983 through the generosity of ASCE President Arthur S. Tuttle, supports graduate students in civil engineering. Up to four students may receive this annual fellowship, which is intended for their first year of graduate studies. Candidates must be members of the American Society of Civil Engineers and demonstrate financial need and educational merit. This fellowship promotes the development of future civil engineering professionals.

The Felix E. Martin Jr. Foundation Community Leadership Fund provides essential support for leadership development in Muhlenberg County, KY. It aims to empower individuals and groups seeking innovative solutions to local challenges. Eligible applicants include those pursuing personal leadership growth or researching effective community strategies. The fund underscores inclusivity, welcoming diverse applicants without discrimination. This initiative fosters a vibrant community by equipping leaders with the resources needed to effect positive change.

Community Foundation of the Fox River Valley

The Community Foundation of the Fox River Valley is a collection of individual funds and resources given by local citizens to enhance and support the quality of life in the Fox River Valley of Illinois.

We are a tax-exempt public charity that allows individuals, businesses, and non-profit organizations to establish permanent endowments and temporary funds within the confines of one large foundation.

Foundation funds are used to provide grants to non-profit organizations and scholarships to area students. The Foundation also hosts a Youth Engagement in Philanthropy (YEP) program, which helps high school students learn more about philanthropy and empowers them to make a difference in the community.

The Community Foundation of the Fox River Valley serves the City of Aurora, Kane County, and Kendall County within the State of Illinois.

Clemens-Clair Future Educators Scholarship Fund

This scholarship is named for Clemens J. Rosen and Clair J. Hemphill – two fathers who encouraged and paid for their daughters to pursue college educations. Both believed an educated woman had more opportunities and would be better able to take care of herself and her family.

Clemens Rosen (1919-2016) did not finish grade school as he was needed on the farm. However, nobody could beat him in Scrabble. He served in WWII on a B24, was shot down twice and was held in a Nazi POW camp until the end of the war. He then took employment in Peoria, IL, first working for Western Electric and then as a foreman for Caterpillar Tractor Company.

Clair Hemphill (1912-1979) finished high school and was a life-long farmer in Elwood, Illinois. Clair’s father was a farmer as was his grandfather and others before him. Clair’s mother was a teacher until she married. He had a strong belief in women pursuing education and was proud that his daughter did just that.

This scholarship is a $10,000 scholarship, awarding $5,000 for two consecutive years providing that students maintain their enrollment status. 

The Festivals and Special Events (FEST) Grants Program, administered by the Miami-Dade Department of Cultural Affairs, supports major annual events from October 1 to September 30. New applicants must consult with staff at least one week before applying. Key dates include a consultation period from February 3 to March 3, 2025, with application deadlines on March 3 and March 7, and final submissions due by April 1, 2025. This program aims to enhance Miami-Dade's cultural reputation.

The Fund for a Just Society Grant, offered by the Unitarian Universalist Association, supports nonprofit organizations that focus on social and economic justice through community organizing. This grant prioritizes innovative projects that seek systemic change and empower disenfranchised communities. Eligible organizations must operate with an annual budget under $500,000 and demonstrate a clear campaign for change. This funding aims to foster a more just society by addressing root causes and enhancing visibility for Unitarian Universalist principles.

Society of Teachers of Family Medicine (STFM) 

Founded in 1967, the Society of Teachers of Family Medicine (STFM) is a national community of academic leaders committed to developing an accomplished family medicine workforce, prepared to serve as the foundation of America’s health care system. Our members include physicians, PAs, nurse practitioners, behavioral health specialists, researchers, pharmacists, nurses and other health care professionals, health system executives, administrators, coordinators, fellows, residents, students, and others involved in the education of family physicians. 

Lynn & Joan Carmichael STFM Recognition Award

The Lynn and Joan Carmichael STFM Recognition Award honors an STFM member or nonmember for outstanding leadership in advancing family medicine as a discipline. The nominee's achievements and activities should be clearly recognized as enhancing or supporting family medicine education by improving resources available for its support, by defense or support of its objectives, or by other notable service to the discipline. Such achievements should have had significance at a national level.

The Prof. Chan Two-Year College Award for the Engaged Teaching of Biology recognizes outstanding contributions by Two-Year College faculty who develop and implement innovative, inclusive pedagogical approaches. Sponsored by Sarah McBride and John Melville, this award emphasizes the impact of teaching on a broader student population and includes a $500 travel grant for the NABT Professional Development Conference, fostering professional development and collaboration among biology educators.

About PLTW Computer SciencePLTW Computer Science students are technology trailblazers who are empowered through transportable skills and prepared to start their career, whether that is in computer science or not.

Lockheed Martin has committed funds to support PLTW grants to schools interested in adding PLTW.Since 2007, Lockheed Martin has partnered with PLTW to address the nation's critical need for future engineers, computer scientists, and math- and science-trained professionals, and to equip all students with the knowledge and skills they need to thrive. Lockheed Martin supports PLTW programs in school districts across the nation and has contributed to the development of PLTW's middle school and high school courses focused on aerospace engineering and flight. Since the first school district partnership in 2014, over 855 PLTW programs have been implemented and more than 145,328 students have gained access to PLTW.Program Requirements:

• Grantee must offer at least one PLTW Computer Science course in the 2027-2028 academic year.
• Grantee may implement any PLTW Computer Science course of their choosing

Grant Award and Distribution Schedule:

• Total Award: $10,000
  • 2027-2028: $10,000

John A. & Louise V. Maslin Scholarship

Essay:

• On the topic “The Importance of Art, Science or Math in Society.”

Award:

• One time award of $1,000.