Best Large Grants for Nonprofit Organizations in Florida

The Grief Reach: Changemaker Supported Community Expansion Cycle offers up to $110,000 to enhance community programs for grieving children. Organizations are encouraged to innovate and expand their services to better meet community needs. The initiative, in partnership with the Judi’s House/JAG Institute, emphasizes training and resources for effective program evaluation over a three-year period, culminating in impactful community expansion projects.

The National Fish Passage Program (NFPP) offers vital assistance for removing barriers to aquatic life, enhancing safety, and promoting local economies. By investing in projects like culvert replacements and floodplain restorations, the program not only supports native fish populations but also delivers significant economic benefits, estimated at $1.5 million for every $1 million invested. With a recent allocation of $15 million, including $5 million for specific restoration initiatives, NFPP continues to advance aquatic connectivity nationwide.

Stanislaus Community Foundation provides scholarship opportunities for students in order to help them achieve their educational and career goals. We believe that by investing in our students, we are investing in a brighter future for Stanislaus. 

Delta Kappa Gamma Scholarship Fund

Applicants must be students currently enrolled in a teaching credential program, current student teachers, current teacher interns, students enrolled in a speech therapy program, or students enrolled in a school psychology program. Colleges considered: CSU Stanislaus, U.C. Merced, U.O.P., UMass Global, Teachers College of San Joaquin, Sacramento State University and CSU East Bay.

Award Amount:

• $3,000

The AGA-Bern Schwartz Family Fund Research Scholar Award in Pancreatic Cancer provides $100,000 annually for three years to early-career faculty in digestive disease research. This award aims to support independent careers in pancreatic cancer research by protecting a significant portion of the recipient's time for research activities. Eligible applicants must hold an MD, PhD, or equivalent and work at a North American institution, with AGA membership required. Strong encouragement is given to underrepresented groups.

The AGA-Bern Schwartz Family Fund Research Scholar Award in Pancreatic Cancer provides $100,000 annually for three years to early-career faculty focused on independent research in pancreatic cancer. This award aims to protect at least 50% of the recipient's time for research activities. Eligible applicants must hold an MD or PhD and be classified as early-career. The award encourages physician-scientists and underrepresented groups in biomedical research to apply, supporting innovative research that can lead to significant advancements in understanding pancreatic cancer.

The CDC's Comprehensive Suicide Prevention Program for States aims to enhance public health approaches to suicide prevention across the U.S. By targeting high-risk groups, such as veterans and rural populations, the program utilizes data to identify prevention areas, assess existing programs, and implement evidence-based strategies. Key outcomes include improved partner engagement and a measurable reduction in suicide rates. This initiative allows potential applicants to prepare by reviewing relevant data and forming strategic partnerships ahead of future opportunities.

This funding opportunity aims to enhance a web-based ordering portal for distributing 1.5 million HIV and STI self-tests to high-burden communities. By optimizing access to these self-tests, the initiative seeks to raise awareness, prevent new infections, and improve the health outcomes of users, thereby contributing to better overall public health and wellbeing.

The Syringe Service Program Grant, offered by The Comer Family Foundation, aims to enhance harm reduction initiatives by funding syringe access programs across the U.S. These programs provide sterile syringes, education, and support services to mitigate the risks associated with drug use, including HIV and hepatitis transmission. Priority is given to organizations in underserved areas and those led by marginalized communities. Grants are available for operational costs, program development, and staff training, with a focus on sustainability and local partnerships.

Request for Proposals

Community Care Corps encourages organizations across the country to apply for 18-month grants ($30,000–$200,000) to develop and scale innovative volunteer programs that provide nonmedical assistance to older adults, adults age 18 and older with disabilities and family caregivers.

Projects funded through this initiative will increase the number of community-based volunteer programs available to provide nonmedical assistance while decreasing the number of older adults, adults with disabilities, and family caregivers who need assistance in maintaining independence in the community but are unable to obtain help. In doing so, the initiative will strengthen community-based supports that help people maintain independence, reduce unmet needs, and improve overall well-being.

About Colin Farrell FoundationThe Colin Farrell Foundation is committed to transforming the lives of individuals and families living with intellectual disability through education, awareness, advocacy, and innovative programs. Inspired by his two sons, he is excited and deeply humbled by the hope that the Colin Farrell Foundation can help those who the larger systems of governance have neglected.

CFF Innovation GrantsWe’re looking for bold, scalable solutions focused on one or more of these priority areas:

• Affordable co-housing models for individuals and families
• Employer-partnered day programs and inclusive job opportunities
• Tools and technologies that enhance accessibility at home and in community spaces
• Cross-sector collaborations between public, private, and nonprofit organizations

The Quantum in the Community (QIC) Grants aim to enhance health in Palm Beach County by funding organizations that address basic needs like food, housing, and transportation. With grants of up to $25,000 awarded annually, the foundation has invested over $160 million in local nonprofits over its three-decade history. Eligible organizations must be 501(c)(3) designated and have been operating in the county for at least six months, ensuring a meaningful impact on community health.

Generally the Community Foundation's scholarships are awarded to applicants who have high financial need. Applicants with household income exceeding $100,000 are less likely to be awarded, but applying will allow you to be considered for targeted scholarships.

Virginia Valk Fehsenfeld Scholarship

Open to full time undergraduate students who are Kent County residents studying education, dietetics, nutrition, or human services and have a minimum 3.4 GPA.

Music Movement offers grants for music therapy aimed at children and young adults with Autism Spectrum Disorder (ASD) and other developmental challenges. Grants typically range from $1,500 to $2,500, providing financial relief to families seeking therapeutic resources. Eligible applicants include legal guardians of children in the U.S. who select qualified therapists. The organization focuses on enhancing communication, social skills, and emotional well-being through music, benefiting diverse communities and promoting personal growth.

The Instrument Donations Program by Music Movement supports children and young adults with Autism and learning differences by providing funding for musical instruments. This initiative fosters self-expression, personal growth, and emotional well-being through music. Grants typically range from $500 to $1,500 and are available to applicants within the United States. The program encourages artistic development and enhances social skills, making a significant impact on the lives of those facing developmental challenges.

Music Movement's Independent Living Initiatives grant supports individuals with Autism and developmental differences in the U.S. Grants, typically ranging from $1,500 to $5,000, aid in various areas including independent living, camps, and continued education. Applicants must be legal guardians of eligible individuals aged 18 and older. The grant portal will reopen for submissions on March 28, 2026, encouraging early review of guidelines to ensure complete applications.

Who We Are

Buiding a stronger, More Vibrant Community

For over 70 years, the Scranton Area Community Foundation has served Northeastern Pennsylvania as a steward of charitable resources, a grantmaker, and a catalyst for positive change. Guided by our core values of collaboration, trust, integrity, innovation, and inclusivity, we work to ensure that our communities thrive with opportunities for all.

This scholarship is awarded to a student who intends to pursue nursing or a related field of study at a college or university, and who demonstrates academic achievement, good citizenship, service to others, leadership, and financial need.

The Bob Skiera Memorial Fund Building Bridges Initiative Grant Program supports urban forestry research and collaboration. With a maximum award of $30,000, it aims to enhance communication between arborists, urban foresters, and various professionals. The program welcomes proposals that explore the benefits of urban forests, policy implementation, and ecosystem services. This initiative honors Bob Skiera's legacy, fostering trust and cooperation within the urban planning community for sustainable urban forestry practices.

The USA Dry Pea and Lentil Council (USADPLC) invites research proposals for pulse crops, focusing on breeding, nutrition, crop management, and product development for the 2023-24 fiscal year. Projects should adopt a transdisciplinary approach to tackle complex challenges, with average awards around $30,000. Researchers are encouraged to leverage industry funding for matching grants. Note that equipment purchases over $10,000 are not eligible. Compliance with specific proposal guidelines is essential.

St. Baldrick's Foundation

The St. Baldrick's Foundation is a volunteer and donor powered charity committed to supporting the most promising research to find cures for childhood cancers and give survivors long and healthy lives. It started with a friendly dare: would you shave your head to raise money for kids’ cancer research? What happened next would change the world. This bold act of baldness has gained major momentum, since its start in 2000. Today, we have more than 1,000 head-shaving events taking place around the world at pubs, restaurants, schools, churches, parks, firehouses, military bases – you name it. It is our constituents’ way of changing the world, in a meaningful way. Volunteers also raise funds through athletic challenges, livestream fundraisers and many other activities.

Since the Foundation's first grants as an independent charity in 2005, St. Baldrick's has invested more than $380 million in childhood cancer research grants worldwide.

About Allied World

Allied World Assurance Company Holdings, Ltd, through its subsidiaries, is a global provider of insurance and reinsurance solutions. The company operates under the brand Allied World and has supported clients, cedents and trading partners with thoughtful service and meaningful coverages since 2001. Since the inception of St. Baldrick’s, Allied World has supported childhood cancer research through the Foundation, and it is the largest of many reinsurance company sponsors, making this life-saving mission a top priority.

Survivorship and Supportive Care Research Grant

These grants are for specific one-year research projects which are hypothesis-driven and focus on areas related to survivorship and supportive care of children and adolescents with cancer. Examples include but are not limited to: studies related to the burden of morbidity, cause-specific mortality, understanding the pathogenesis of treatment-related complications, patient-reported outcomes or quality of life, health communication, health promotion, and psychosocial support across the trajectory from diagnosis to survivorship or end-of-life care.

Projects must have direct applicability and relevance to pediatric cancer. They may be in any discipline of basic, clinical, translational, or epidemiological research.

The Alliance for Innovation on Maternal Health (AIM) Capacity Program aims to enhance the capacity of state, territorial, and Tribal entities in the U.S. to implement and sustain AIM Patient Safety Bundles. By promoting evidence-based maternal safety practices, the program strives to improve the quality of maternity care, enhance maternal health outcomes, and significantly reduce preventable maternal mortality and severe morbidity.

The Presenter Consortium for Jazz Grant, offered by Chamber Music America, supports U.S.-based presenters collaborating to engage professional jazz ensembles. This grant provides up to $39,000 for expenses like ensemble fees, concert production, and marketing. Each consortium can include up to three presenters and aims to enhance the jazz experience through live performances and streamed concerts. Eligible projects must involve CMA’s New Jazz Works grantees, fostering creativity and community engagement in jazz.

The Ryan White HIV/AIDS Program Part D provides supplemental funding aimed at enhancing the infrastructure and capacity of organizations to deliver high-quality, family-centered HIV care services. This initiative focuses on two key areas: HIV Care Innovation and Infrastructure Development, ensuring improved access to essential services for women, infants, children, and youth affected by HIV.

The Ryan White HIV/AIDS Program Part B AIDS Drug Assistance Program Training and Technical Assistance aims to enhance the capacity of ADAPs. By providing essential tools and expert guidance, the program seeks to improve health outcomes for individuals living with HIV in an evolving healthcare landscape. This initiative is funded by the US HHS through the Health Resources & Services Administration, ensuring support and resources are effectively allocated to meet the needs of vulnerable populations.

The Joseph O. & Geraldine C. Waymire Nursing Scholarship, established by the Waymire family, supports students pursuing nursing careers. It is open to high school seniors from accredited Marion County institutions and those enrolled in nursing programs at various educational levels. Funds can be used for tuition, fees, and other educational expenses. The scholarship aims to foster a diverse nursing workforce, reflecting the mission of the Central Indiana Community Foundation to enhance community opportunities.

Catholic Extension's Enhancing Pastoral and Social Ministry Grants aim to empower the church to broaden its outreach and foster societal transformation through targeted pastoral and social initiatives. This program supports specific elements of the church's ministerial efforts, including funding for catechetical resources, marriage and family ministries, and social outreach for vulnerable populations. By investing in these areas, Catholic Extension seeks to enhance the church's role in communities, especially following disasters.

The Celine Wyatt Memorial Scholarship honors a remarkable young athlete who embodied determination and leadership. This scholarship is aimed at empowering high school senior girls from Ohio, Kentucky, West Virginia, or Pennsylvania who excel in softball and aspire to pursue higher education. By supporting these young women, the scholarship continues Celine's legacy of positivity, resilience, and encouragement, ensuring that her spirit of hard work and dedication inspires future generations of student-athletes.

The RSLAAIS Leadership Award, presented by the American Academy of Allergy, Asthma & Immunology (AAAAI), honors exemplary leaders within state, regional, or local allergy societies. This prestigious award recognizes individuals for their significant contributions to community involvement, clinical education, and the advancement of the AAAAI's mission. Candidates are nominated by the RSLAAIS Board of Governors and must demonstrate a commitment to enhancing their local allergy societies and the broader medical community.