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Best Large Grants for Nonprofit Organizations in Florida

Find the perfect Large Grants for Nonprofit Organizations in Florida on Instrumentl. 10,000+ Large Grants for Nonprofit Organizations in Florida in the United States.

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$2.64B

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$5K

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10,000+ grants
$2.64B total
$5K median

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Lakken’s Legacy Survivor Scholarship

Childrens Brain Tumor Foundation Inc.
Private
United States
US $1,000
The Lakken’s Legacy Survivor Scholarship, offered by the Children’s Brain Tumor Foundation, awards $1,000 to brain tumor survivors pursuing education beyond high school. This initiative honors Lakken, who faced challenges during her cancer journey yet remained passionate about education. The scholarship aims to support individuals diagnosed with brain or spinal cord tumors before age 21, ensuring they have the opportunity to continue their studies in various educational institutions. It's a commitment to empower survivors and foster their dreams.
Education - Higher Education Vocational & Trade Education Education - High School +2 more

Lakken’s Legacy Sibling Scholarship

Childrens Brain Tumor Foundation Inc.
Private
United States
US $1,000
The Lakken’s Legacy Sibling Scholarship, established by the Children’s Brain Tumor Foundation, honors Lakken Burzynski's courage and resilience in her battle with cancer. This $1,000 scholarship is designed for siblings of children diagnosed with brain tumors, emphasizing support for families impacted by such challenges. Eligible applicants must be 21 or younger at diagnosis and reside in the U.S. This initiative promotes positivity and hope, continuing Lakken's legacy of strength and family support.
Education - Higher Education Vocational & Trade Education Education - High School +2 more

HEAL Foundation Grant

The Heal Foundation Inc
Private
Baker County, Florida, Clay County, Florida +3 more
Up to US $2,500

The Heal Foundation Inc

The focus of the HEAL Foundation is what our acronym stands for - Helping Enrich Autistic Lives. Our mission is inspiring, educating and funding services for those affected by autism in our community.

Since its inception, HEAL has granted nearly $4 million dollars, providing funding for autism service dogs, summer camps, sports leagues, music programs, art programs at the Cummer Museum and MOCA, golf camps at TPC Sawgrass, surf camps, support groups, weekend and after school programs. Additionally, HEAL has gifted 600 iPads and 300 trikes to local schools K-12.

Today, a staggering 1 in 31 are diagnosed with autism, 4 out of 5 are boys, and the need is dire. We are grateful for the support from our generous community, our Board of Directors, Jr Board - TEAM HEAL and hundreds of volunteers. Last year, we hit a milestone of serving our community for 20 years. In that timeframe, HEAL has made tremendous strides in assisting thousands in our community. Together, we continue Helping Enrich Autistic Lives.

HEAL Foundation Grant

HEAL's grant giving is focused on smaller grass roots organizations to build, enhance and strengthen their programs. In keeping with the vision and mission of HEAL, funds for Spring and Fall grants will be considered for those who demonstrate our mission and vision.

Mission: Inspiring, educating, and funding services for those affected by autism in our community.

Vision: Make our community the best place to live for those affected by autism

Autism Special Needs Education Summer Camps

Robert J. O’Connor Memorial Scholarship Fund

Community Foundation of the Fox River Valley
Private
United States
Unspecified amount

Community Foundation of the Fox River Valley

The Community Foundation of the Fox River Valley is a collection of individual funds and resources given by local citizens to enhance and support the quality of life in the Fox River Valley of Illinois.

We are a tax-exempt public charity that allows individuals, businesses, and non-profit organizations to establish permanent endowments and temporary funds within the confines of one large foundation.

Foundation funds are used to provide grants to non-profit organizations and scholarships to area students. The Foundation also hosts a Youth Engagement in Philanthropy (YEP) program, which helps high school students learn more about philanthropy and empowers them to make a difference in the community.

The Community Foundation of the Fox River Valley serves the City of Aurora, Kane County, and Kendall County within the State of Illinois.

Robert J. O’Connor Memorial Scholarship Fund

The Robert J. O’Connor Memorial Scholarship Fund was created as a way to honor his long-standing relationship with the Community Foundation and the passion he held for helping local students pursue their educational goals. Bob’s connection to the Community Foundation started when he was the recipient of a scholarship as a 1962 graduate of East Aurora High School. He would later serve nine years as a Foundation Board member.

Education - Higher Education Education - High School Academic Scholarship Programs +2 more

Veterans Food Assistance Program

Disabled Veterans National Foundation
Private
United States
Unspecified amount

Disabled Veterans National Foundation

The Disabled Veterans National Foundation (DVNF) was established in 2007 to support veterans facing challenges that traditional systems could not fully address. From its earliest days, DVNF has been focused on closing critical gaps in care and providing resources that help veterans rebuild their lives with dignity and stability.

Guided by this commitment, DVNF developed its Health & Comfort programs, offering emergency financial assistance, housing transition support, food assistance, comfort kits, and wellness initiatives. These programs are designed to meet veterans where they are and to provide practical solutions that restore hope and stability. Today, DVNF continues to grow as a trusted national nonprofit. Every day, our team works with a clear purpose: to change lives for the men and women who have served our country.

Veterans Food Assistance Program

It is our goal to ensure that no veteran goes hungry by providing essential food assistance and household support, fostering stability and well-being in the lives of our veterans and their families.

The Veterans Food Assistance Program (VFAP) is designed to provide a one-time grant of essential food and household support to veterans and their families, ensuring no veteran goes hungry. With the rising cost of living, especially food prices due to inflation, this program offers a much-needed lifeline to those who have served our country. Once approved, the DVNF program team will handle the shopping for you.

The Veterans Food Assistance Program provides a one-time grant per household to support different family sizes, given the rising cost of food:

  • Married Veterans Grant Allowance
    • Married - No Children up to $250
    • Married - 1 Child up to $300
    • Married - 2 Children up to $450
    • Married - 3+ Children up to $500
  • Single Veterans Grant Allowance
    • Single - No Children up to $200
    • Single - 1 Child up to $300
    • Single - 2 Children up to $350
    • Single - 3+ Children up to $450
Military & Veterans Services Food Access & Hunger Food Security

Carson Bailey Memorial Scholarship for Siblings

Childrens Brain Tumor Foundation Inc.
Private
United States
US $1,000
The Carson Bailey Memorial Scholarship for Siblings, established by the Children’s Brain Tumor Foundation, honors the memory of Carson Bailey. This scholarship aims to support brain tumor survivors pursuing their educational goals. Eligible applicants must have been diagnosed with a brain or spinal cord tumor before age 21, reside in the U.S., maintain a GPA of 2.0 or higher, and be at least a senior in high school. A $1000 scholarship is available for those attending various educational institutions.
Education - Higher Education Vocational & Trade Education Education - High School +2 more

Mechanisms that Impact Cancer Risk after Bariatric Surgery (R21 Clinical Trial Not Allowed) (356342)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $275,000
The National Cancer Institute (NCI) invites applications for studies on mechanisms by which bariatric surgery influences cancer risk. This funding opportunity encourages exploration beyond short-term outcomes like weight loss and diabetes. The goal is to support innovative proof of concept studies, emphasizing feasibility without prior development in the literature. Unpublished data is not allowed, but references from preprints with a DOI are acceptable. Deadlines for applications span from February 2025 to November 2027.
Cancer / Oncology Surgery Obesity

Mechanisms that Impact Cancer Risk after Bariatric Surgery (R01 Clinical Trial Optional) (356341)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $2,500,000
The National Cancer Institute (NCI) is seeking applications for studies that explore how bariatric surgery influences cancer risk, emphasizing the need for innovative research in this area. This funding opportunity encourages the participation of researchers who focus on the long-term impacts of bariatric surgery beyond weight loss and diabetes, addressing critical gaps in understanding the disease mechanisms involved. Key deadlines for application submissions span from February 2025 to October 2027.
Cancer / Oncology Surgery Obesity

Carson Bailey Memorial Scholarship

Childrens Brain Tumor Foundation Inc.
Private
United States
US $1,000
The Carson Bailey Memorial Scholarship, established by the Children's Brain Tumor Foundation, honors the memory of Carson Bailey, a dedicated student and beloved family member. This scholarship is aimed at brain tumor survivors who have been diagnosed before the age of 21 and seek to pursue higher education. It provides $1000 to eligible applicants, supporting their educational aspirations while promoting inclusiveness and respect for all backgrounds within the brain tumor community.
Education - Higher Education Vocational & Trade Education Education - High School +2 more

Indian Housing Block Grant Competitive Program (IHBG-COMP) for FY 2026

US HUD: Office of Public and Indian Housing (PIH)
Federal Government
United States
US $500,000 - US $7,500,000
The Indian Housing Block Grant Competitive Program (IHBG-COMP) for FY 2026 offers competitive grants to eligible recipients under NAHASDA. This program aims to support affordable housing initiatives benefiting low-income Tribal families, enhancing their living conditions and community well-being. Funded by the US HUD's Office of Public and Indian Housing, the IHBG-COMP encourages the development of sustainable housing solutions within Native American communities.
Minority Services Equitable & Affordable Housing Native American Services

Clinical Trials Addressing Unmet Needs of Rare Neurodegenerative Diseases (R01) Clinical Trials Required

US Department of Health & Human Services: Food and Drug Administration (FDA)
Federal Government
United States
US $650,000 - US $900,000
The US Department of Health & Human Services, through the FDA, is funding clinical trials targeting rare neurodegenerative diseases. This initiative aims to enhance treatment options by evaluating the efficacy and safety of new products for both children and adults. By fostering innovative and collaborative trial designs, the FDA seeks to accelerate the approval of new therapies, ultimately benefiting patients with rare conditions and advancing drug development in this critical area.
Pharmacology Drug Safety Neurological Diseases & Disorders +1 more

St. Ignace Area Community Foundation: CTE Technical Scholarship

St. Ignace Area Community Foundation
Association/Society
United States
Unspecified amount

St. Ignace Area Community Foundation: CTE Technical Scholarship

The St. Ignace Community Fund annually awards scholarships assisting students with higher education, technical training, vocational training or retraining based largely on acknowledgement of student responsibility, community service, and civic involvement. These Scholarships are made possible through the generosity of donors to the various accounts within the St. Ignace Area Community Fund. Some accounts specifically are awarded to recognize higher education in the areas of special education, vocational/technical careers, teaching, law enforcement, and health care.

Vocational & Trade Education Nursing Special Needs Education +2 more

Charles B. Decker Memorial Scholarship

Adirondack Foundation
Private
United States
Unspecified amount
The Charles B. Decker Memorial Scholarship, established in 1991, supports college and graduate students from the Tri-Lakes area pursuing journalism careers. This scholarship emphasizes the importance of education in the Adirondack region by providing essential financial assistance to students dedicated to journalism. Candidates are evaluated based on financial need, demonstrated commitment to journalism, and academic achievements, ensuring that the scholarship aligns with the foundation's mission to invest in educational opportunities.
Education - Higher Education Education - High School Academic Scholarship Programs +2 more

Limited Competition: Tribal Institutional Review Board Establishment and Enhancement (TIRBEE)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
United States
Unspecified amount
The TIRBEE funding opportunity supports federally-recognized Tribes and Tribal Entities in establishing or enhancing Institutional Review Boards. This initiative aims to strengthen the capacity for biomedical research involving human participants within these communities by improving review and oversight capabilities. Eligible organizations are invited to apply, with applications subject to NIH's standard peer-review process to ensure only the most meritorious proposals are considered.
Epidemiology & Public Health Native American Services Health Disparities & Social Determinants of Health +1 more

Washington County 4-H Dairy Scholarship

Community Foundation of Washington County Maryland
Private
United States
Unspecified amount

This Community Foundation was created by and for the people of Washington County MD, and exists to improve the quality of life for all of our citizens, now and for generations to come, by building community endowments, addressing needs through grant making and providing leadership on key community issues.

Washington County 4-H Dairy Scholarship

Established to support post-secondary scholarships to participants in Washington County 4-H dairy programs.

Education - Higher Education Livestock & Ranching Agricultural Economics +1 more

Washington County 4-H Livestock/Market Sale Scholarship

Community Foundation of Washington County Maryland
Private
United States
Unspecified amount

This Community Foundation was created by and for the people of Washington County MD, and exists to improve the quality of life for all of our citizens, now and for generations to come, by building community endowments, addressing needs through grant making and providing leadership on key community issues.

Washington County 4-H Livestock/Market Sale Scholarship

Established to support post-secondary scholarships to participants in Washington County 4-H Livestock and Market Sale programs.

Education - Higher Education Livestock & Ranching Agricultural Economics +1 more

Edith M. Pritchard Scholarship

Nurses Educational Funds Inc.
Private
United States
Unspecified amount
The Edith M. Pritchard Scholarship, offered by Nurses Educational Funds Inc., supports nurses pursuing master's or doctoral degrees in nursing education and public health. Applicants must hold a current RN license, maintain a GPA of 3.6, and have at least two semesters of study remaining post-award notification. This scholarship promotes nursing leadership and is funded through donations, reflecting over a century of commitment to nursing education.
Education - Higher Education Nursing Mental Health & Psychiatric Diseases +2 more

Judith Heavenrich Memorial Scholarship

Saginaw Community Foundation
Private
United States
US $500 - US $4,000
The Judith Heavenrich Memorial Scholarship, established in memory of Judith Heavenrich, aims to support single, low-income mothers in Saginaw County as they pursue higher education or vocational training. Judith, a lifelong advocate for education and environmental issues, faced numerous challenges in her life but remained dedicated to her community. This scholarship reflects her spirit and commitment to empowering women to achieve their educational goals, with awards typically ranging from $500 to $4,000.
Education - Higher Education Education - High School Academic Scholarship Programs +3 more

Heiser Fund for Leprosy Research Grant

The New York Community Trust
Private
United States
US $87,500 - US $250,000
The Heiser Program for Research in Leprosy, established by Dr. Victor G. Heiser, focuses on innovative biomedical research to combat leprosy. Since 1975, it has funded over 200 grants totaling more than $20 million, supporting early-career researchers and significant projects. The program aims to enhance diagnostic tools, improve treatments, and implement effective surveillance strategies. With a dedicated Scientific Advisory Committee, it ensures rigorous proposal reviews and fosters collaboration among grantees, ultimately advancing leprosy elimination efforts.
Pharmacology Eye Diseases & Disorders Respiratory Diseases & Systems +1 more

Herbek Humanitarian Award

College Of American Pathologists Foundation
Private
United States
Up to US $1,500
The Herbek Humanitarian Award honors a CAP member pathologist for significant contributions to the See, Test & Treat® program, which offers free cancer screenings to underserved women. Established in 2011, it commemorates Gene N. Herbek, MD, FCAP, who pioneered this initiative for Native Americans. Nominees must have led or significantly contributed to the program, with submissions due by May 3, 2024. Self-nominations or incomplete entries will not be accepted, ensuring high standards in recognition.
Reproductive Health Breast Cancer Women's Health

A. Wlock and E. Woodruff Scholarship

Saginaw Community Foundation
Private
United States
Unspecified amount

A. Wlock and E. Woodruff Scholarship

The A. Wlock and E. Woodruff Scholarship was created by Emilee Woodruff and Autumn Wlock’s family and the W2 Foundation in loving memory of Emilee and Autumn. Emilee and Autumn passed away in February 2020 when a fire destroyed their home. Emilee was diagnosed with epilepsy as a preteen. Autumn was Emilee’s first child and love of her life. Emilee was a great mother and Autumn was a happy baby. This scholarship is aimed to help students attend college that have been affected by a fire or who have been diagnosed with epilepsy.  

Education - Higher Education Epilepsy Career / College Preparation

Allison Adams Wieczorek Scholarship

Nurses Educational Funds Inc.
Private
United States
Unspecified amount
The Allison Adams Wieczorek Scholarship supports graduate nurses pursuing degrees in maternal-infant and pediatric nursing. Established through the Nurses Educational Funds, Inc., this scholarship honors the contributions of Allison Adams Wieczorek, a dedicated board member with extensive experience in financial services. Applicants must have at least two semesters of study remaining and meet specific eligibility criteria, including holding a current RN license and maintaining a minimum GPA of 3.6. This initiative fosters nursing leadership and education.
Education - Higher Education Nursing Mental Health & Psychiatric Diseases +2 more

Esserman-Knight Journalism Awards

The Miami Foundation
Private
Broward County, Florida, Miami-Dade County, Florida +2 more
US $1,000 - US $10,000

The Miami Foundation

We were established as the Dade Foundation in 1967, with our founders calling us “a living philanthropy in perpetuity.” In 1987, we were renamed Dade Community Foundation to better reflect our identity and mission. In 2010, we became The Miami Foundation, seizing on the strength of a placename that’s known across the globe.

Since 1967, The Foundation has invested over $772M to strengthen our community in partnership with more than 1,000 fundholders and 50,000 donors.

Esserman-Knight Journalism Awards

The Esserman-Knight Journalism Awards honor excellence in investigative and public service reporting that exposes injustice, elevates community voices and holds the powerful to account in South Florida.

Nominations are open to recognize journalists, student journalists, newsrooms, public media outlets, and documentary filmmakers for outstanding original local reporting about local issues within Miami-Dade, Broward, Palm Beach or Monroe counties. 

Submissions may include:

  • A single piece or a series of up to three related pieces
  • Nominations are encouraged across different mediums, including print, digital, television, radio, podcasts, video, audio, data visualization, and documentary film (up to 120 minutes in length are eligible)

Anyone can nominate a journalist or team of journalists. Self-nominations are not accepted.

Submissions will be judged by the rigor of newsgathering, quality of storytelling, inclusion of community voices, and the impact on public understanding or action. Jurors include highly experienced professional journalists, members of the community and members of the Esserman family.

The awards recognize multiple forms of excellence in journalism, including accountability reporting, explanatory reporting, beat reporting, local community reporting, and student journalism. 

Journalism Documentaries News Media & Communications

Learning Seed Foundation Scholarship

Community Foundation of South Puget Sound
Private
United States
US $3,000

About Scholarships

Through the incredible generosity of our donors, the Community Foundation of South Puget Sound manages 26 scholarship funds that offer a wide range of scholarship awards and encourage students of all backgrounds and educational interests to apply. We also want to extend a sincere thank you to our many scholarship donors, advisors, and scholarship committee members for their investment in our student's bright futures this year and for many years to come!

Learning Seed Foundation Scholarship

The Learning Seed Foundation Scholarship Fund was established by the Learning Seed Foundation to assist graduating high school seniors in Thurston and Pierce counties in obtaining a higher education. This scholarship is designed to benefit primarily students of color who have overcome significant obstacles and demonstrate a commitment to others. The scholarship has the potential to be renewed for up to an additional 3 years of undergraduate education. Reapplication each year is required.

Education - Higher Education Career / College Preparation Black American Services +1 more

Graham Foundation: Grants To Organizations

Graham Foundation for Advanced Studies in the Fine Arts
Private
United States
Up to US $30,000
The Graham Foundation for Advanced Studies in the Fine Arts offers grants to organizations focused on architecture and its role in society. Established in 1956, the Foundation promotes innovative projects that encourage public dialogue, raise awareness, and foster experimentation in the field. Grants, not exceeding $30,000, support diverse practitioners and initiatives, enhancing discourse in architecture, design, visual arts, and related fields. The Foundation encourages projects that demonstrate originality, feasibility, and potential for meaningful impact.
Architecture Urban Planning Landscape Architecture

Graham Foundation: Grants To Individuals

Graham Foundation for Advanced Studies in the Fine Arts
Private
United States
Up to US $20,000
The Graham Foundation for Advanced Studies in the Fine Arts, established in 1956, supports innovative projects that explore architecture's role in society and culture. It offers grants to individuals for production and presentation, as well as research and development, focusing on diverse ideas that provoke critical dialogue. The foundation prioritizes first-time applicants and seeks to amplify underrepresented perspectives while fostering collaboration across various disciplines in the arts and education.
Architecture Landscape Architecture Urban Planning

NAFC Patient Care Fund

National Association of Free and Charitable Clinics Inc
Private
United States
US $20,000

NAFC Open Grant/Product Donation Applications

The National Association of Free and Charitable Clinics (NAFC) is the only nonprofit 501c(3) organization whose mission is solely focused on the issues and needs of the medically underserved throughout the nation and the more than 1,400 Free and Charitable Clinics that serve them. The NAFC has earned the Platinum Seal of Transparency from GuideStar and a 4-Star rating from Charity Navigator. Founded in 2001 and headquartered near Washington, D.C., the NAFC is working to ensure that the medically underserved have access to affordable quality healthcare and strives to be a national voice promoting quality healthcare for all. For more information about the NAFC, including how to become a member, please visit https://www.nafcclinics.org.

NAFC Patient Care Fund

The NAFC Patient Care Fund supports direct patient services that expand immediate access to care. This funding is designed to help NAFC members meet urgent patient needs by supporting clinical supplies, expanded services, contracted providers, transportation assistance, medication access, and other direct care resources.

Patient Care & Services Health Care Access & Delivery Health Facilities & Clinics +1 more

Large Grants for Nonprofit Organizations in Florida Highlights

Looking for large grants for nonprofit organizations in Florida?


Read more about each grant below or start your 14-day free trial to see all large grants for nonprofit organizations in Florida recommended for your specific programs.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Large Grants for Nonprofit Organizations in Florida

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

300+ Large Grants for Nonprofit Organizations in Florida grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

64 Large Grants for Nonprofit Organizations in Florida over $25K in average grant size

49 Large Grants for Nonprofit Organizations in Florida over $50K in average grant size

41 Large Grants for Nonprofit Organizations in Florida supporting general operating expenses

200+ Large Grants for Nonprofit Organizations in Florida supporting programs / projects

3,000+ Grants on Instrumentl focused on Education

600+ Grants on Instrumentl focused on Food Access & Hunger

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Large grants for Nonprofit Organizations in Florida?

Most grants are due in the first quarter.

Q1
27.5%
Q2
26.3%
Q3
23.2%
Q4
23.0%

Typical Funding Amounts

What's the typical grant amount funded for Large Grants for Nonprofit Organizations in Florida?

Grants are most commonly $12,500.

$100 $100 Min.
$12,500 $12.5 K Median
$487,658 $487.7 K Average
$40,331,313 $40.3 M Max.

Average Grant Size

What's the typical amount funded for Florida?

Grants are most commonly $127,766.

$127,766

Total Number of Grants

What's the total number of grants in Large Grants for Nonprofit Organizations in Florida year over year?

In 2024, funders in Florida awarded a total of 120,990 grants.

2022 107,491

2023 109,840

2024 120,990

Top Grant Focus Areas

Among all the Large Grants for Nonprofit Organizations in Florida given out in Florida, the most popular focus areas that receive funding are Philanthropy, Voluntarism & Grantmaking Foundations, Education, and Human Services.

1. Philanthropy, Voluntarism & Grantmaking Foundations

2. Education

3. Human Services

Funding Over Time

How is funding for Large Grants for Nonprofit Organizations in Florida changing over time?

Funding has increased by 4.30%.

2022 $14,150,322,449

2023 $14,761,745,220
4.32%

2024 $15,396,491,509
4.30%

Florida Counties That Receive the Most Funding

How does grant funding vary by county?

Miami Dade County, Orange County, and Hillsborough County receive the most funding.

County Total Grant Funding in 2024
Miami Dade County $5,036,107,623
Orange County $3,251,041,805
Hillsborough County $2,859,448,977
Broward County $2,438,211,409
Palm Beach County $2,225,921,170

Related Grants in Florida

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