Best Foundation Grants for Nonprofits in Mississippi

The Draper Richards Kaplan Foundation provides grants to early-stage social entrepreneurs working on scalable solutions to pressing social and environmental issues. By supporting organizations with innovative approaches and proven impact, they aim to uplift underserved communities globally. The foundation offers operational support, funding of up to $300,000 over three years, and fosters a collaborative community among its portfolio organizations. They focus on candidates demonstrating measurable impact and sustainable growth potential.

Entergy’s Open Grants Program aims to enhance community well-being through funding initiatives in arts, education, social services, and community improvement. The program prioritizes support for organizations that serve diverse populations, including children and low-income communities. Eligible entities must have 501(c)(3) status or equivalent nonprofit recognition. Applications should be submitted three months in advance, allowing ample time for review. Entergy focuses on projects that foster self-sufficiency and enrich local neighborhoods.

The Hearst Foundation: Culture Grant aims to support outstanding nonprofits that enhance cultural engagement and artistic talent in the U.S. With a focus on programs that reach young people, the grant prioritizes organizations that create lasting impacts in the arts and sciences. The Foundation allocates 25% of its funding to cultural initiatives, favoring established organizations with a history of significant results. Eligible nonprofits must encourage inclusivity and sustainability in their programs.

The Phil Hardin Foundation Grant aims to enhance educational and life outcomes for children and youth in Mississippi, particularly in Meridian and Lauderdale County. The foundation prioritizes proposals that demonstrate a regional or statewide impact, focusing on areas like early childhood development, literacy, and equitable access to educational resources. It encourages collaboration among educational institutions and community organizations, fostering partnerships to improve educational quality and cultural enrichment across Mississippi.

South Arts, Inc. offers Professional Development Grants for Arts Organizations to enhance the skills and knowledge of Southern arts entities. These grants aim to support operational stability and growth, focusing on organizations with budgets of $500,000 or less. Eligible applicants include a range of arts organizations within South Arts' nine-state service area. The program emphasizes first-time opportunities and requires a dollar-for-dollar cash match, ensuring a commitment to professional development in the arts.

Roche Corporate Donations and Philanthropy (CDP) focuses on impactful projects that foster sustainable development, engage employees, and leverage Roche's expertise. Their philanthropic efforts prioritize humanitarian, educational, environmental, and cultural initiatives, aiming to build stronger communities and support innovative projects. Eligibility is limited to local organizations, while ineligible projects include those with political or religious ties. The foundation strives to create a positive societal impact through collaboration and strategic partnerships.

The Semnani Family Foundation, established in 1993, is dedicated to supporting marginalized communities worldwide through health, education, and disaster relief initiatives. Founded by Khosrow and Ghazaleh Semnani, it began by funding an orphanage in Romania. The foundation also operates locally, providing free healthcare through the Maliheh Free Clinic in Utah. Its commitment to human welfare drives impactful partnerships in countries such as Afghanistan, India, and South Africa, focusing on the most vulnerable populations.

The Bank of America Foundation Sponsorship Program aims to enhance economic mobility and social progress in low- and moderate-income communities through partnerships with nonprofit organizations. This initiative focuses on critical areas such as workforce education, basic needs like food and housing, and community development. The Foundation invested $350 million last year and encourages employee volunteerism and giving, supporting nonprofits in various sectors, including arts, culture, and diversity initiatives.

The Penn National Gaming Foundation Grants support various community initiatives across North America, emphasizing education, health services, and cultural affairs. Launched post-Hurricane Katrina, the foundation aids local nonprofits, enhancing community development, public safety, and veteran support. The grants cater to organizations that address the needs of children, senior citizens, and disadvantaged populations, ensuring a broad impact in areas where Penn National Gaming operates. This commitment reflects the foundation's dedication to uplifting communities and fostering resilience.

The Mutual of America Foundation Community Partnership Award honors exemplary nonprofit organizations in the U.S. that foster collaborative partnerships across sectors. Annually, a national competition showcases numerous organizations demonstrating impactful community partnerships. Six organizations receive recognition, including the Thomas J. Moran Award, which offers $100,000, and the Frances R. Hesselbein Award, granting $75,000. Since 1996, the award has acknowledged 262 partnerships, emphasizing Mutual of America's commitment to societal improvement through collaboration.

The Community Foundation of Northwest Mississippi offers competitive grants to support health and education initiatives, particularly for youth and children. Their four key focus areas include Early Childhood Education, Place-Based Education & Civic Engagement, Technology in Education, and the Future of Northwest Mississippi. Organizations with 501(c)(3) status in specified counties can apply once a year, between July 1st and August 1st, making a significant impact in the community.

The Assisi Foundation of Memphis Grant supports nonprofit organizations in improving community health, education, social justice, cultural enrichment, and capacity building. Grants are available for organizations in specific Tennessee, Arkansas, and Mississippi counties, with eligibility focused on tax-exempt entities. Applications are accepted quarterly, with specific deadlines for different focus areas. The foundation seeks innovative ideas that align with its philanthropic mission and encourages organizations to apply for funding that promotes positive community transformation.

The Abelard Foundation, established in 1958, supports progressive social change projects located east of the Mississippi River. With an average grant size of $12,000, they prioritize new initiatives with budgets under $350,000. The foundation emphasizes community organizing, civil rights, and empowering marginalized groups. Eligible applicants must be associated with a nonprofit organization and demonstrate a commitment to local leadership and broader policy connections. The board meets biannually to decide on approximately 15 grants per year, focusing mainly on general support.

The Community Foundation of Greater Memphis offers Nonprofit Capacity Building Grants to enhance the organizational health of nonprofits in the Mid-South. These one-time financial grants, averaging $15,000 with a total of $210,000 available, are for projects that improve governance and management, rather than direct programming. Organizations must raise matching funds dollar-for-dollar to leverage additional resources. Eligibility requires a reviewed profile on LIVEGIVEmidsouth.org and meeting specific operational criteria.

Toyota Motor Manufacturing, Mississippi, Inc. (TMMMS) Grants aim to create impactful community partnerships through funding initiatives that enhance quality of life. The program focuses on STEM education and workforce readiness, supporting eligible 501(c)(3) nonprofits, public schools, and governmental organizations in specific counties. Toyota emphasizes sustainable, long-term benefits, engaging volunteers and sharing expertise to foster inclusivity and address pressing community challenges.

The Hancock Whitney Opportunity Grant, in collaboration with the Greater New Orleans Foundation, invites applications from eligible nonprofits starting October 7, 2025. This grant aims to enhance capacity building and sustainability for organizations focused on food insecurity, workforce development, and youth programs. Eligible applicants include 501(c)(3) organizations serving low to moderate-income communities within Hancock Whitney's service areas, fostering impactful changes with AmeriCorps support.

The Dudley T. Dougherty Foundation Grant supports nonprofit charitable organizations recognized under section 501(c)(3) of the IRS Revenue Code. Established in 2002, the foundation aims to empower groups committed to positive change, fostering respect for life and the environment. Their vision emphasizes collaboration for a better future, encouraging applicants to embody these values in their initiatives. With a focus on impactful projects, this grant is an opportunity for organizations striving to make a critical difference in our world.

The GCCF: Anthony Dartez Endowment Fund Grant supports non-profit organizations enhancing the quality of life for South Mississippi citizens. Established in 1995 in memory of Anthony Dartez, it provides funding for training and educational services for the physically and mentally challenged. With a mission to increase philanthropy, the Gulf Coast Community Foundation has distributed over $90 million to various charitable causes since its inception in 1989, benefiting local grassroots organizations.

The Nissan Foundation Grants support nonprofit organizations that promote cultural diversity and heritage. Established in 1992, the foundation focuses on enhancing community quality of life where Nissan operates. Eligible organizations must have 501(c)(3) status, be active for over three years, and serve specific communities. Ineligible programs include those not aligned with the foundation's mission, such as disease advocacy and political activities. The foundation does not provide multi-year grants, but organizations can reapply for funding in subsequent cycles.

South Arts, Inc. offers Literary Arts Grants to support Southern independent publishers and small presses with funding up to $5,000. These grants aim to amplify contemporary literary arts and foster community engagement through projects like reading series and festivals. Eligible applicants must be based in the South Arts Region and demonstrate a commitment to advancing literary traditions. This initiative enhances access to the arts and promotes cultural vitality across the Southern states.

South Arts Inc. is offering Literary Arts Grants to support writers, independent publishers, and literary organizations focusing on contemporary literature in the Southern U.S. Grants of up to $5,000 will fund projects in poetry, fiction, and other genres. Eligible applicants must be full-time residents of the South Arts region. The initiative aims to amplify the literary traditions of the American South, fostering creativity and community engagement through diverse literary projects.

The NRA Foundation offers financial support through its Grant Program, aimed at projects that promote firearms safety, shooting sports education, and research for improved marksmanship techniques. Eligible applicants include IRS-recognized entities and government bodies. The foundation does not fund commercial ventures, administrative costs, or projects requiring NRA membership. Grants support educational programs related to firearms and public safety, fostering community engagement in shooting sports and hunting safety.

Ameriprise Community Grants focus on supporting nonprofits that enhance community vitality and meet basic needs. With over 120 years of commitment to philanthropy, Ameriprise Financial engages employees in volunteerism and grantmaking. Key giving areas include hunger relief, housing stability, and community development. Priority is given to organizations with active volunteer engagement from Ameriprise advisors and employees, creating a meaningful impact on financial independence and community resilience.

The MGM Resorts Foundation Community Grant Fund supports nonprofit agencies providing essential services in areas such as affordable housing, education, and health. Grants are awarded for a one-year period and focus on regions where MGM Resorts employees live and work. Eligible applicants must comply with diversity policies and serve individuals or families. The foundation does not fund governmental agencies or projects exclusively for medical research. This initiative aims to enhance community well-being through targeted support.

Entergy’s Open Grants Program in Mississippi aims to enhance community well-being through support for arts, education, poverty solutions, and health initiatives. The program prioritizes requests from organizations with 501(c)(3) status and local projects that improve public access to the arts and promote self-sufficiency. Funding is not available for utility payments, political activities, or religious organizations. Preference is given to projects serving Entergy's customer areas, ensuring community-focused impact.

The True Inspiration Awards, established by Chick-fil-A in 2015, recognizes nonprofit organizations that significantly impact their communities. In 2025, the program will distribute $6 million in grants, ranging from $30,000 to $350,000, to sixteen selected organizations. Categories include Caring for People, Caring through Food, Community, and Caring for our Planet, with a focus on educational initiatives, food security, housing services, and environmental stewardship, honoring the legacy of founder S. Truett Cathy.

The Hubert E. Sapp Regular Grant Cycle, by Southern Partners Fund, aims to empower rural communities in the Southeastern U.S. through grassroots leadership and organizing. The fund provides support to nonprofit organizations focused on social, economic, and environmental justice. Eligible applicants are community-based organizations with budgets under $350,000. The initiative honors Hubert E. Sapp's legacy, promoting equitable relationships that drive real transformation and community decision-making.