Best Houston County Grants for Nonprofits in Minnesota

The Somatic Mosaicism across Human Tissues (SMaHT) Program aims to enhance our understanding of biological processes driven by somatic mutations in human tissues through innovative technology development. Since its inception in 2023, the program has produced multi-omic datasets from human tissues representing all germ layers. The NIH is now advancing to Stage 2, focusing on collaborative efforts to refine and implement validated technologies for somatic mutation detection and functional interpretation, promoting rigorous and cost-effective methodologies.

The Cancer Prevention and Control Programs aim to eliminate cancer through collaborative efforts among state, territorial, and tribal organizations. Funded by the CDC, this program supports initiatives such as breast and cervical cancer screening, cancer control planning, and cancer surveillance. By fostering partnerships and community involvement, the program seeks to improve health outcomes and achieve the mission of 'All People Free of Cancer.' This comprehensive approach ensures that resources are effectively coordinated to address the cancer burden in communities.

This funding opportunity from the US Dept. of Health & Human Services: National Institutes of Health (NIH) aims to advance mechanistic research on metal exposure and its effects on human health. Studies should focus on biological processes altered by metals, including their absorption, transport, and immune interactions. Innovative methodologies and human biospecimens are encouraged to explore how metals might impact immune homeostasis and cross biological barriers, providing insights into health risks associated with metal exposure.

The TURTLE Program aims to empower Tribal Entities by fostering a skilled workforce in biomedical research. It supports undergraduate and graduate students in health research, ensuring they complete their degrees and transition into impactful careers. With phased awards, the program emphasizes effective training and mentoring, inviting eligible organizations to apply. Applications will undergo NIH's peer-review process, ensuring only the most meritorious proposals are funded, ultimately enhancing Tribal health research capabilities.

The TIRBEE funding opportunity supports federally-recognized Tribes and Tribal Entities in establishing or enhancing Institutional Review Boards. This initiative aims to strengthen the capacity for biomedical research involving human participants within these communities by improving review and oversight capabilities. Eligible organizations are invited to apply, with applications subject to NIH's standard peer-review process to ensure only the most meritorious proposals are considered.

The Somatic Mosaicism across Human Tissues (SMaHT) Program aims to enhance our understanding of somatic mutations and their impact on human biology and disease. This initiative will establish a Tissue Procurement Center (TPC) to collect and provide clinically relevant tissue samples from a diverse set of healthy donors. The TPC will support ongoing research by ensuring high-quality, well-characterized specimens are available for functional analyses, advancing the field of somatic mosaicism.

The Somatic Mosaicism across Human Tissues (SMaHT) Program aims to enhance understanding of biological processes and disease mechanisms due to somatic mutations in human tissues. Since 2023, it has produced multi-omic datasets from various human tissues. The NIH plans to advance this initiative by establishing the National Somatic Mosaicism Commons Data Analysis & Organizational Center, which will oversee data management, develop analytical tools, and provide training to facilitate research and clinical applications.

Parks and Trails Legacy grants

Provides funding for parks and trails of regional significance outside of the seven-county metropolitan area. Applications for this program are submitted directly to the Greater Minnesota Regional Parks and Trails Commission (GMRPTC). The GMRPTC submits funding recommendations to the legislature. The legislature then appropriates funding to the Department of Natural Resources to award and administer the grants. Please visit the GMRPTC web page for application and contact information.

The Greater Minnesota Regional Parks and Trails Commission was established in 2013 to undertake system planning and provide recommendations to the legislature for grants funded by the parks and trails fund to counties and cities outside the seven-county metropolitan area for parks and trails of regional significance. Minnesota Statutes, 85.536 .

The John H. Prescott Marine Mammal Rescue Assistance Grant supports the recovery and care of sick or injured marine mammals through federal assistance to the U.S. National Marine Mammal Stranding and Entanglement Response Networks. Eligible applicants must provide a Prescott Letter of Eligibility, confirming their participation in the network. This program aims to enhance marine mammal health monitoring and response capabilities across the country, ensuring timely and effective interventions for stranded marine life.

The BJA FY 2026 DNA Capacity Enhancement for Backlog Reduction (CEBR) Competitive Grants Program aims to enhance the capacity of state and local government crime laboratories for processing DNA samples. This program focuses on using DNA technology to improve forensic efficiency and implement Rapid DNA in booking stations. It targets jurisdictions with operational challenges, ensuring fair access to funding. Eligible agencies can apply for both competitive and formula CEBR funding.

The National Institute of Neurological Disorders and Stroke (NINDS) aims to enhance research on Amyotrophic Lateral Sclerosis (ALS) through intermediate patient population expanded access protocols. These protocols will provide investigational drugs to ALS patients while collecting vital data to inform future treatments and care strategies. This initiative seeks to better understand the disease's biomarkers, patient experiences, and the overall impact of investigational therapies, fostering advancements in ALS research and care.

American Cancer Society

The mission of the American Cancer Society is to improve the lives of people with cancer and their families through advocacy, research, and patient support, to ensure everyone has an opportunity to prevent, detect, treat, and survive cancer.

ACS Research Priority Areas

The American Cancer Society (ACS) has identified these 6 areas to categorize and track the research we fund to help advance our mission. Applicants (except Institutional Research Grants and Professor grants) are asked to select at least 1 of these research areas that aligns with their proposal:

• Etiology (causes of cancer)
• Obesity/Healthy Eating and Active Living (HEAL)
• Screening and Diagnosis
• Treatment
• Survivorship
• Health Equity Across the Cancer Continuum

Research Scholar Grants

Research Scholar Grants (RSG) provide support for independent, self-directed researchers.

Applicants' institutions must provide space and other resources customary for independent investigators.

Grant proposals are investigator-initiated and may pursue questions across the cancer research continuum, as long as they fit within an American Cancer Society (ACS) priority research area.

These grants typically contribute to the cost of salaries, consumable supplies, and other miscellaneous items required in the research. 

Research Scholar Grants are funded up to $215,000 per year (direct costs), plus 10% allowable indirect costs, with a project period up to four years.

MSAB Creative Support for Individuals Grant

Project grants to help individual artists and culture bearers develop or sustain their creative practices and meaningfully engage with Minnesotans. Grantees may use funds to support their creative practice and meaningfully connect to and engage with audiences, participants, students, and/or communities during the grant period.

Applicants may be working in a variety of art forms including dance, media arts, music, photography, poetry, prose, theater, two-dimensional or three-dimensional visual art. Culture bearers refers to individuals who have been trained by traditional elders or master artists and whose artistic practice is reflective of the cultural life of a community that shares a common ethnicity, geographic or regional identity, language, or tribal affiliation.

Program outcome

This program exists to support artists and culture bearers as they sustain their artistic practices and maintain their connections to Minnesota residents and communities. The program’s intended outcome is: Artists and culture bearers engage Minnesotans in their creative practice.

Grant range

Applicants may request between $2,000 - $10,000. No cash match is required.

Minnesota Weatherization Assistance Program

The Weatherization Assistance Program provides free home energy upgrades to income-eligible homeowners and renters to help save energy and make sure your home is a healthy and safe place to live.

Weatherization works closely with its companion program, the Energy Assistance Program, to help permanently reduce the energy bills for low-income Minnesotans.

If you qualify, a local Weatherization service provider may conduct a free home energy assessment to determine if cost-effective energy efficiency improvements can be completed in your home. Weatherization services could help decrease your annual energy costs by up to 30 percent. 

Potential energy upgrades include: 

• Exterior wall and attic insulation
• Air leakage reduction
• Furnace, boiler, and water heater repair or replacement
• Ideas to help you reduce your home’s energy use, such as using a programmable thermostat

The Weatherization Assistance Program uses the previous calendar month of household income to determine eligibility. Households that have received Temporary Assistance for Needy Families (TANF) or Supplemental Security Income (SSI) within the last 12 months are also eligible. Priority is given to households with elderly or disabled members, households with children, and households determined to be high energy consumers, and those with a high energy burden. 

Weatherization Assistance is a nationwide, federally funded program of the U.S. Departments of Energy and Health and Human Services. Each state administers its Weatherization program to meet the unique needs of its low-income residents. 

Protecting Minnesota’s water resources takes more than good intentions — it requires practical tools and support. The Minnesota Agricultural Water Quality Certification Program (MAWQCP) provides farmers and landowners with the resources they need to put conservation into action.

MAWQCP Climate Smart Farms Endorsement

The Climate Smart Farm Endorsement recognizes producers who incorporate approved climate-based practices into their systems.

• Endorsed producers receive the Farmers’ Guide to Carbon Market Contracts in Minnesota, published by the Minnesota Farmers Union in partnership with Farmers’ Legal Action Group and MAWQCP.
• A $1,000 payment supports producers as they explore evolving climate marketplaces and public programs. Applications are accepted online.
• To apply, contact your area certification specialist.

Who We Are

Broad Street Children's Foundation is committed to providing financial support to privately funded children's homes caring for the orphaned, abandoned and broken children right here in the United States.

Grant Seekers

Broad Street Children's Foundation supports self-sustaining children's homes across the United States that actively foster the development of strong, well-rounded children in their care.

Since the start of the Foundation, over $1,000,000.00 in grants have been donated to children's homes across the country. Additionally, through the Bill and Jackie Hazelgrove Scholarship Program, we have been able to assist a number of young people to continue their education and work towards a college or vocational degree.

Today, the Broad Street Children's Foundation is continuing the dream of it's original founders through the second generation. Equally as dedicated to changing the lives of children in need across America and striving to break the cycle of abuse and neglect for other children and their families.

Local Road Improvement Program

The Local Road Improvement Program (LRIP) was established by the Minnesota legislature in 2002 and is defined in Minnesota Statute 174.52. The legislature appropriated $50,000,000 in general obligation (GO) bonds (of which $3,000,000 is designated for grants to townships) in Laws of Minnesota 2026 Session, Chapter 130, Article 1, Section 16, Subdivision 2. Depending on the number and quality of applications received, projects will be selected from this program for counties, state aid cities, non-state aid cities, and townships for the 2026 LRIP solicitation.

The LRIP provides funding for capital construction costs only – LRIP funds cannot be used for engineering, right-of-way, construction administration or other non-construction related costs. The statute describes three types of accounts with a specific intent for the types of local road projects that can be considered for the program. 

The program’s goal is to provide funding assistance for roadway construction, reconstruction, or reconditioning projects.

Funding Availability

The competitive 2026 LRIP appropriation provides $50,000,000 in general obligation (GO) bond funding. Grant requests must range from a minimum of $50,000 to a maximum of $1,500,000 per project. Tribes are eligible to receive general funds only and are encouraged to partner with local entities on project

The Easement Restoration and Stewardship program, funded by the USDA NRCS, focuses on restoring and managing Wetland and Floodplain Easements. It includes developing restoration plans, conducting assessments, and implementing stewardship activities to enhance ecological health. Awardees will collaborate with NRCS personnel to ensure effective restoration design and maintenance strategies, fostering sustainable landscapes. This initiative addresses critical habitat conditions and promotes long-term environmental benefits for protected lands.

The Deployed Warfighter Protection FY27 program aims to safeguard military personnel from disease-carrying arthropods, including ticks and mosquitoes. It seeks innovative research to develop new insecticides, improve existing formulations, and enhance personal protection technologies. The initiative also focuses on effective pesticide application equipment, addressing both current and emerging arthropod threats. This program is crucial for maintaining the health and safety of deployed military forces.

The National Institute of Allergy and Infectious Diseases (NIAID) is advancing Type 1 diabetes research by exploring the innate immune system's role in disease onset. This initiative aims to identify genetic and environmental factors contributing to Type 1 diabetes through multidisciplinary teams. By employing innovative methodologies, the program seeks to determine how immune responses affect pancreatic tissues, potentially leading to early detection and prevention strategies for at-risk individuals.

The Collaborative Centers in Children’s Environmental Health Research and Translation program aims to establish a national network of research centers focused on improving children's health through innovative research and public health strategies. By fostering collaboration within the children’s environmental health community, these centers will lead the way in translating scientific findings into actionable practices, ensuring a healthier future for children while addressing emerging environmental threats.

The Immune Drivers of Autoimmune Disease (IDAD) network, supported by NIAID, aims to uncover early triggers and mechanisms of autoimmunity to prevent disease. Key initiatives include developing predictive tools and biomarkers, fostering preclinical cohorts, and utilizing AI and big data. The network will leverage shared infrastructure for collaborative research, managed by the IDAD Network Coordinating Center, which ensures coordination and resource sharing among awardees. This initiative is crucial for advancing understanding and prevention of autoimmune diseases.

About Us

advancing the science of water ®

Who We Are

The Water Research Foundation (WRF) is the leading research organization advancing the science of all water to meet the evolving needs of its subscribers and the water sector. WRF is a 501(c)(3) nonprofit, educational organization that funds, manages, and publishes research on the technology, operation, and management of drinking water, wastewater, reuse, and stormwater systems—all in pursuit of ensuring water quality and improving water services to the public.

5427 - Advancing Actionable Climate Resilience Metrics for Water Supply Planning

Grant Information

• Catalog existing performance metrics that consistently drive water utility operational and capital decisions, assess their applicability to support future resilience-based decision making under nonstationary climate conditions, and identify adjustments or alternative metrics needed to support forward-looking, resilience-based decision making for water utilities.
• Determine the appropriate level of climate resilience analysis needed to evaluate and apply climate resilience metrics, with requirements scaled based on metric sensitivity to climate change, decision context, and utility characteristics.
• Develop guidance to integrate climate resilience metrics into planning and decision processes.

The BJA FY 2026 Prosecuting Cold Cases Using DNA program aims to enhance public safety and justice by supporting prosecutors in the investigation and prosecution of violent cold case crimes with developed DNA profiles. This funding opportunity, provided by the US DOJ's OJP Bureau of Justice Assistance, facilitates crucial investigative and forensic activities to increase successful prosecutions and provide resolution for victims and their families. Full applications are due by November 5, 2026.

The BJA FY 2026 Veterans Treatment Court Program aims to enhance operations for veterans in the criminal justice system, focusing on reducing substance use, including opioids and alcohol. It integrates treatment for substance use and mental health disorders within a judicial framework, targeting high-risk veterans. This initiative not only addresses public safety concerns but also aims to provide necessary support and resources for veterans dealing with issues like PTSD and traumatic brain injury, fostering rehabilitation and recovery.