Best Addiction and Substance Abuse Grants in Indiana

The Bethany Legacy Foundation Grant supports organizations in Jefferson County, focusing on innovative solutions for mental and physical health challenges. This grant is open to 501(c)(3) non-profits, churches, and government entities, promoting projects that serve the community and create lasting, positive change. Priority is given to initiatives that align with the Foundation's core focus areas and demonstrate collaboration, sustainability, and a commitment to accessibility for all residents.

The Richard M. Fairbanks Foundation Grant Program focuses on enhancing the vitality of Indianapolis through targeted grantmaking in education, health, and economic development. The program prioritizes support for tax-exempt organizations that align with its goals, addressing critical issues such as public health, academic outcomes, and workforce development. By fostering collaboration and sharing data-driven insights, the Foundation aims to create a more vibrant, equitable city where all residents can thrive.

The National Institute on Drug Abuse (NIDA) invites applications for longitudinal cohort studies focusing on HIV and substance use. This initiative aims to foster multidisciplinary research addressing HIV-associated co-morbidities and substance use disorders. The program encourages collaboration with a NIDA-funded Coordinating Center to enhance research agendas that align with NIH-HIV priorities, ensuring impactful policy and practice outcomes in the field of HIV/AIDS and substance use.

The Academic Research Enhancement Award (AREA) supports small-scale research grants for institutions with limited NIH funding, emphasizing biomedical research experiences for undergraduates. Eligible institutions must award baccalaureate science degrees and have received no more than $6 million in NIH support over the past seven years. This initiative aims to enhance the research environment at these institutions, fostering student involvement in research activities.

The Wabash Valley Community Foundation is launching the Supporting Grants initiative aimed at enhancing community well-being in Clay, Sullivan, and Vigo counties. With a $1 million fund, the program focuses on mental health, substance use, and homelessness, seeking to establish impactful partnerships with nonprofit organizations and government entities. Grants of up to $10,000 will be awarded to projects that demonstrate proven efficacy and contribute to sustainable community improvement. This initiative underscores the Foundation's commitment to fostering a healthy and thriving environment.

Agility Grants, initiated by the National Council on Problem Gambling, aim to minimize gambling-related harm through funding nonprofit organizations for innovative prevention programs. These grants focus on addressing gaps in services and enhancing existing initiatives. Eligible applicants include U.S.-based 501(c)(3) organizations, with priority given to projects targeting at-risk populations. The program emphasizes community impact and requires evaluations to assess effectiveness, fostering collaboration and awareness within diverse communities affected by gambling.

The Community Foundation of Howard County offers Strategic Grants to support initiatives that enhance community well-being. Focus areas include mental health, economic growth, and cultural diversity. Eligible organizations must be 501(c)(3) tax-exempt entities benefiting Howard County residents. The Foundation emphasizes inclusivity and aims to remove barriers to access services. Notably, grants are not awarded for individual projects or prior costs. First-time applicants are encouraged to consult the Foundation before submission.

The NAILBA Charitable Foundation Grant aims to support small, well-managed U.S. charities that assist those in need, particularly children. Grants are available to organizations with backing from a NAILBA member and that meet specific criteria, such as nonsectarian operation and appropriate fiscal accountability. Since its inception in 2002, the foundation has invested in community transformation by funding initiatives that directly engage in beneficial services, thereby enhancing the welfare of underprivileged groups.

The Alvah H. and Wyline P. Chapman Foundation offers grants to support charitable, educational, and community-focused initiatives, primarily in Florida and Georgia. Eligible applicants must be IRS-recognized 501(c)(3) organizations. The foundation prioritizes projects that address children's welfare, education, multicultural understanding, substance abuse prevention, and homelessness. Grants typically do not exceed $15,000, and proposals must be endorsed by a Foundation Director. Interested parties should submit a Letter of Inquiry for consideration.

The APA Foundation's Helping Hands Grants provide up to $5,000 to medical schools for projects aimed at improving mental health education and assistance in under-served communities. Initiated in 2005, this program empowers medical students to lead initiatives that promote awareness of mental illness and encourage community service, particularly among minority populations. By partnering with community agencies, these projects foster a deeper interest in psychiatry while addressing critical mental health needs.

The NIDA Mentor-Facilitated Training Award aims to accelerate the dissemination of substance use disorder research, particularly focusing on opioid use disorder. This award supports trainees in developing expertise through mentorship and project completion, ultimately enhancing the adoption of evidence-based practices in healthcare settings. With a budget of up to $12,000, the award fosters professional growth and encourages the implementation of SUD treatment strategies, addressing critical knowledge gaps in clinical practice.

The Avant Garde Award supports innovative research on HIV and substance use disorders, encouraging creative scientists to explore high-risk, high-reward approaches. While applications are not currently being accepted, this initiative by the National Institute on Drug Abuse (NIDA) aims to stimulate collaborations and impactful research. Early-stage investigators are particularly encouraged to consider this opportunity as they develop their proposals for future funding. The program uses the DP1 activity code, fostering transformative advancements in biomedical and behavioral science.

The Jennie K. Scaife Charitable Foundation Grant focuses on enhancing family support, women's and children's health, and animal welfare. It aims to fund programs that promote beneficial human-animal interactions and early intervention in addiction prevention. Eligible organizations must have a valid 501(c)(3) designation. Grants align with at least one of the foundation's focus areas, ensuring impactful contributions to community welfare and well-being.

The AMA Foundation Award for Health Education recognizes the exemplary educational efforts of physicians, medical students, and residents dedicated to improving public health. Supported by a $3,500 stipend from the John P. McGovern Foundation, this award celebrates individuals who demonstrate outstanding commitment to service, community involvement, and leadership in health education. Eligible candidates include practicing physicians, with special consideration for those addressing issues related to alcohol, tobacco, and other drugs.

The Bernau Family Foundation Grant aims to enhance individual lives and foster positive leadership through funding initiatives that provide long-term solutions. Grants are awarded to IRS-designated public charities or nonprofits, emphasizing projects that promote civic responsibility, education, and mentor programs. The foundation prioritizes smaller organizations that encourage meaningful community engagement and constructive change, ensuring a lasting impact on society.

The Albert G. and Olive H. Schlink Foundation, established in 1966, has significantly impacted Ohio's nonprofit sector by increasing its annual grant distribution from an initial $500 to over $1.4 million in 2023. The Foundation prioritizes organizations with ties to Erie and Huron Counties and emphasizes thoughtful evaluation of all grant applications. With a focus on community needs, it continues to honor the founders' legacy while adapting to the evolving demands of local nonprofits.

The National Institute on Drug Abuse (NIDA) aims to establish a Center for the Advancement of Substance Use Disorder (SUD) Pharmacotherapeutics. This Center will educate researchers on product development for SUD therapies and provide technical and financial support for initial experiments. It encourages collaboration and outreach to enhance research efforts in drug addiction. Investigators with relevant expertise are invited to consider applying for future opportunities to develop impactful solutions in SUD pharmacotherapeutics.

The HEAL Initiative aims to address the significant overlap between chronic pain (CP) and opioid use disorder (OUD), with 40-75% of individuals affected by both. The IMPOWR project focuses on testing innovative interventions and implementation strategies to integrate care for CP and OUD across various health systems. The BEACON Center will enhance network coordination, build capacity, and develop resources to address barriers in service delivery, ultimately improving sustainability and scalability of evidence-based practices.

The Patient-Centered Outcomes Research Institute (PCORI) will announce the Phased Large Awards for Comparative Effectiveness Research on December 2, 2025. This funding aims to support high-quality, patient-centered comparative clinical effectiveness research projects. The initiative encourages applicants to engage with patients and stakeholders to address critical healthcare dilemmas and improve decision-making. Projects should compare established clinical alternatives with evidence of efficacy, targeting vital health issues across diverse populations.

The Mibor Realtor Foundation Grant, offered by the Mibor Foundation Inc, aims to combat homelessness in central Indiana by funding 501(c)(3) non-profits. Since its inception, the Foundation has allocated over $3 million to support organizations that provide permanent housing solutions. Eligible entities can request funding up to $20,000, with typical awards ranging from $5,000 to $15,000. The Foundation prioritizes proven housing-based solutions linked with comprehensive support services.

The HEAL Initiative aims to address the complex interplay between chronic pain and opioid use disorder (OUD), affecting 40-60% of OUD patients. Through the IMPOWR initiative, this funding opportunity seeks to develop integrated care strategies that enhance treatment delivery at health systems levels. By identifying effective interventions and collaborative care models, the initiative strives to improve patient outcomes in managing both chronic pain and OUD, while emphasizing the roles of various healthcare professionals in this integrated approach.

The J.W. Couch Foundation Grant focuses on supporting Wildlife Conservation nonprofit organizations that align with their mission of community betterment and environmental protection. The foundation seeks partnerships with organizations that promote animal wellbeing, early childhood education, teacher support, and outdoor activities. Eligible applicants must be registered 501(c)3 nonprofits or for-profit entities aligned with their charitable programs. This grant emphasizes collaboration and community engagement to create lasting impacts.

The Sidney Stern Memorial Trust Grant supports charitable, scientific, medical, and educational organizations that are 501(c)(3) certified. This private funder emphasizes impactful service to diverse populations without discrimination. Grants must be utilized within the United States and cannot be awarded to individuals, political candidates, or lobbying efforts. The Trust is dedicated to enhancing the general welfare through soundly-managed initiatives that contribute significantly to community needs.

The Costco Wholesale Charitable Contributions program prioritizes support for children, education, and health services within local communities. Nonprofit organizations seeking assistance must be 501(c)(3) certified and focus on monetary requests. Applications are reviewed within 4-6 weeks, factoring in community needs and collaboration. However, Costco limits grants to 10% of the program budget and typically restricts organizations to one request per fiscal year. They do not fund individuals or direct aid for various specific purposes.

The Mutual of America Foundation Community Partnership Award honors exemplary nonprofit organizations in the U.S. that foster collaborative partnerships across sectors. Annually, a national competition showcases numerous organizations demonstrating impactful community partnerships. Six organizations receive recognition, including the Thomas J. Moran Award, which offers $100,000, and the Frances R. Hesselbein Award, granting $75,000. Since 1996, the award has acknowledged 262 partnerships, emphasizing Mutual of America's commitment to societal improvement through collaboration.

The Bank of America Foundation Sponsorship Program aims to enhance economic mobility and social progress in low- and moderate-income communities through partnerships with nonprofit organizations. This initiative focuses on critical areas such as workforce education, basic needs like food and housing, and community development. The Foundation invested $350 million last year and encourages employee volunteerism and giving, supporting nonprofits in various sectors, including arts, culture, and diversity initiatives.

State Farm's Good Neighbor Citizenship Company Grants aim to enhance community safety, development, and education. Focused on long-term impact, they support initiatives in auto and home safety, disaster preparedness, affordable housing, and educational programs. Eligible recipients include nonprofits, educational institutions, and government entities. However, funding is not available for individuals, religious programs, or organizations outside the U.S. By addressing critical community needs, these grants foster safer and more resilient neighborhoods.