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Best Macon County Grants for Nonprofits in Illinois

Looking for grants for 501(c)(3) nonprofit organizations working in Macon County, Illinois? Find the perfect grant for your nonprofit on Instrumentl.

9,000+

Available grants

$2.86B

Total funding

$5K

Median grant

9,000+ grants
$2.86B total
$5K median

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9,401 Results based on applied filters

Vilcek Foundation Grants

The Vilcek Foundation Inc
Private
American Samoa, Guam +4 more
US $5,000 - US $20,000
The 2025 Vilcek Foundation Grants aim to support nonprofit organizations that celebrate immigrant contributions to the arts and sciences. The foundation invites applications from organizations operating under U.S. IRS Section 501(c)(3) that promote diversity and inclusivity. Grants will be prioritized for new partners and those in states without prior funding. This initiative underscores the foundation's commitment to fostering appreciation for immigrant communities and their impact on society.
Immigrant Services Art & Culture Education - Higher Education +1 more

Birth Equity Innovation Seed Grants (IL)

Illinois Department of Public Health
State/Local Government
Illinois
Up to US $200,000
The Birth Equity Innovation Seed Grants in Illinois aim to support community organizations working to reduce disparities in maternal and infant health. Funding will be available for programs tied to communities most affected by these inequities, facilitating access to essential maternal care services. The Illinois Department of Public Health encourages innovative approaches that establish or maintain programs focused on improving birth equity, particularly for marginalized populations. Grants range from $0 to $1,000,000.
Maternal And Perinatal Health Obstetrics & Neonatal Care Health Disparities & Social Determinants of Health

Reboot Representation Grant

Reboot Representation Tech Coalition
Association/Society
United States
Unspecified amount
The Reboot Representation Tech Coalition aims to significantly increase the number of Black, Latina, and Native American women earning computing bachelor’s degrees. They invite qualified organizations to submit grant inquiries focused on recruiting and retaining these women in tech. Programs that leverage existing resources and operate across multiple regions will be prioritized, and the Coalition seeks initiatives backed by substantial research and community trust.
Computer Science & Engineering Diversity, Equity & Inclusion Women's Rights & Equality +4 more

Biomedical Research Environment and Sponsored Programs Administration Development (BRE-SPAD) Program (UC2- Clinical Trial Not Allowed)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $2,500,000
The Biomedical Research Environment and Sponsored Programs Administration Development (BRE-SPAD) Program, funded by the NIH, aims to enhance the biomedical research landscape by supporting resource-limited organizations. It targets domestic institutions with limited research resources and few doctoral students in biomedical fields, promoting broader participation in research and boosting administrative capacities for sponsored programs. Applications are due by 5:00 PM local time of the applicant organization, ensuring timely submissions.
Biology Health & Medicine

Enhancing Mechanistic Research on Precision Probiotic Therapies (R61/R33 Clinical Trial Optional) (356925)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $1,750,000
This grant opportunity from the NIH aims to enhance mechanistic research on precision probiotic therapies through a biphasic R61/R33 award mechanism. It encourages innovative studies to identify specific biological factors influencing probiotic responses, thereby improving clinical outcomes. The program supports up to five years of research, with the initial phase focused on discovering unique host characteristics and the second phase assessing improvements in probiotic efficacy through rigorous studies.
Integrative & Alternative Health Microbiomes

Enhancing Mechanistic Research on Precision Probiotic Therapies (R33 Clinical Trial Optional) (356927)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $1,400,000
This funding opportunity aims to advance mechanistic research for precision probiotic therapies. It invites R33 applications focused on characterizing individual differences in probiotic responses, identifying responder subgroups, and enhancing clinical outcomes. The goal is to develop strategies addressing barriers to effective probiotic use, accounting for human variability. Proposals should include innovative studies using animal models or human subjects, supported by preliminary data to test biological patterns and their effects on health outcomes.
Biology Microbiology Microbiomes

Extramural Discovery Science Accelerator Award

American Cancer Society
Association/Society
United States
Up to US $75,000
The Extramural Discovery Science Accelerator Award supports the commercialization of ongoing cancer research projects, focusing on experiments that facilitate technology validation and de-risking. Applications are accepted on a rolling basis, with a budget of up to $75,000 for one year. This award encourages independent investigators at any career stage to advance their technologies, with a strong emphasis on commercial viability and collaboration within a learning community.
Cancer / Oncology Medical Technology, Devices, and Equipment

Leukemia Exploration and Prevention Grant Program (LEAP) - Team Award

American Cancer Society
Association/Society
United States
Up to US $1,720,000
The Leukemia Exploration and Prevention Grant Program (LEAP) aims to advance cancer interception and prevention for patients with RUNX1 familial platelet disorder (RUNX1-FPD). This program supports interdisciplinary research teams investigating the mechanisms of leukemogenesis and innovative treatment strategies. With funding of up to $430,000 per year, LEAP encourages projects focused on both understanding clonal evolution and developing novel therapeutic approaches. The initiative seeks to bridge critical knowledge gaps and provide urgent interventions for high-risk populations.
Leukemia

Leukemia Exploration and Prevention Grant Program (LEAP) - Research Scholar Grant

American Cancer Society
Association/Society
United States
Up to US $860,000
The Leukemia Exploration and Prevention Grant Program (LEAP) aims to advance cancer interception and prevention strategies for patients with RUNX1 familial platelet disorder. This initiative, supported by the American Cancer Society, focuses on understanding the mechanisms behind leukemia development and fostering innovative research leading to effective treatment options. Grants of up to $215,000 per year for four years are available, emphasizing the urgent need for targeted therapies in high-risk populations.
Leukemia

Green Chemistry Student Chapter Award

American Chemical Society
Association/Society
United States
Unspecified amount
The Green Chemistry Student Chapter Award recognizes ACS student chapters for their commitment to green chemistry initiatives. This award highlights the importance of green chemistry in education, encouraging students to engage in activities that promote sustainability. Eligible chapters must submit detailed summaries of at least three green chemistry projects, demonstrating their understanding of the principles and practices that contribute to a more sustainable future.
Chemistry

CCRP Initiative: NIH Countermeasures Against Chemical Threats (CounterACT) Basic Research on Chemical Threats that Affect the Nervous System (R01 Clinical Trial Not Allowed) (356935)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $300,000
The CCRP Initiative invites applications for basic research on chemical threats affecting the nervous system, including chemical warfare agents and toxic industrial chemicals. This funding aims to elucidate toxicity mechanisms, explore new toxic exposure manifestations, and identify targets for therapeutic development. Proposals should generate data relevant to understanding these toxic threats, with applications due by 5 PM local time. Optional Letters of Intent are encouraged 30 days prior to the proposal deadline.
Neuroscience Environmental Chemistry & Toxicology Neurological Diseases & Disorders

USF: Community Impact Grant

Usa Swimming Foundation
Private
United States
Up to US $5,000
The USF Community Impact Grant, established by USA Swimming and the USA Swimming Foundation, aims to enhance competitive opportunities in swimming clubs. Grants of up to $5,000 are available for registered USA Swimming clubs committed to fostering community engagement and collaboration. Eligible clubs can renew their grant for up to three years, promoting diverse access to swimming programs. This initiative particularly supports clubs that partner with educational or public entities and those led by women or minorities.
Swimming

USF: HBCU Grant

Usa Swimming Foundation
Private
United States
US $5,000 - US $10,000
The USA Swimming Foundation's HBCU Grant program is a $1 million initiative aimed at enhancing swimming opportunities in communities served by Historically Black Colleges and Universities (HBCUs). Launched in 2021, the program provides annual grants of $100,000 over ten years, supporting youth water safety lessons and university swim clubs. This initiative is designed to empower HBCUs to expand their aquatic programming, fostering inclusivity and safety in swimming across diverse communities nationwide.
Black American Services Swimming Diversity, Equity & Inclusion

USF: Youth Learn-to-Swim Grant

Usa Swimming Foundation
Private
United States
Unspecified amount
The USA Swimming Foundation's Youth Learn-to-Swim Grant aims to increase access to swim lessons for children across the nation. By providing funding to swim lesson programs, the foundation ensures that financial barriers do not prevent children from learning this vital life skill. Grants can be used for free or reduced-cost lessons, addressing the needs of underserved communities and promoting safety through swimming education.
Swimming Diversity, Equity & Inclusion

USF: Adult Learn-to-Swim Grants

Usa Swimming Foundation
Private
United States
US $1,000 - US $5,000
The Adult Learn-to-Swim Grants, offered by the USA Swimming Foundation in collaboration with U.S. Masters Swimming, aim to enhance swimming safety for adults aged 18 and over. This initiative provides funding to programs that promote swim education, targeting underserved communities. Grants can be used for expenses like pool rentals and scholarships, with a maximum award of $5,000. The goal is to reduce drowning risks and encourage ongoing participation in swimming activities.
Swimming

Steve's Foundation Grant

Achelis Foundation
Private
United States
US $500 - US $5,000
Steve's Foundation Grant is a small private funding opportunity providing grants between $500 and $5,000, averaging $2,600. It supports organizations that empower disadvantaged individuals, focusing on cost-effective programs that yield significant impacts. The foundation prioritizes proposals from non-profits that directly assist those in need, especially children and marginalized communities. Applications are evaluated annually in May or June, but due to high demand, the foundation cannot respond to every inquiry.
Youth Services Women & Girl Services Poverty Alleviation & Services +2 more

Puffin Foundation: Annual Artist Grant Program - Odd Year Focus

Puffin Foundation Ltd
Private
United States
Up to US $3,500
The Puffin Foundation's Annual Artist Grant Program, focused on odd years, supports individual artists and non-profit organizations in the genres of video/film and theater. Grants, typically around $1,750, aim to uplift marginalized voices in the arts. Applicants must be U.S. citizens or permanent residents with an SSN. The program excludes proposals in other disciplines and projects involving AI. This initiative prioritizes diverse artistic expression and aims to maximize funding impact for those with limited financial resources.
Theater Media Arts

Annual Artist Grant Program - Even Year Focus

Puffin Foundation Ltd
Private
United States
Up to US $3,500
The Puffin Foundation's Annual Artist Grant Program focuses on supporting artists and organizations that are often marginalized. In even years, proposals are accepted in fine arts, music, and photography. With a maximum grant size of $3,500, it aims to empower individuals and groups with limited resources to flourish creatively. This initiative reflects the Foundation's commitment to ensuring diverse artistic expressions thrive in society. Applicants must be U.S. citizens or residents, and only one proposal is permitted per year.
Music Fine Art Photography

NARMS Cooperative Agreement Program to Strengthen Antibiotic Resistance Surveillance in Retail Food Specimens

US Department of Health & Human Services: Food and Drug Administration (FDA)
Federal Government
United States
Unspecified amount
The NARMS Cooperative Agreement Program aims to enhance antibiotic resistance surveillance in retail food specimens, building on the National Antimicrobial Resistance Monitoring System initiated by the FDA in 1996. This program seeks to improve detection of antibiotic-resistant bacteria in food commodities and expand sampling sites. By strengthening monitoring efforts, it aims to protect public health and achieve measurable outcomes aligned with NARMS objectives, contributing to national efforts against antibiotic resistance.
Veterinary Science & Services Animal Food & Drug Safety

Business Attraction Prime Sites

Illinois Department of Commerce and Economic Opportunity (DCEO)
State/Local Government
Illinois
US $250,000 - US $25,000,000
The Business Attraction Prime Sites program, administered by the Illinois Department of Commerce and Economic Opportunity, aims to foster economic growth by supporting large-scale capital investments. This initiative targets companies relocating or expanding in Illinois, promoting job creation through diverse projects, including infrastructure development. Eligible applicants must commit to significant investments and job creation, contributing to a robust economic landscape in the state. The program aligns with strategic industry focuses outlined in the Illinois Economic Plan.
Economic Services & Development Job Creation Manufacturing Engineering +3 more

Aging Research Dissertation Awards to Promote Diversity (R36 Clinical Trial Not Allowed) (357209)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $142,312
The Aging Research Dissertation Awards aim to enhance diversity in the scientific research workforce focused on aging and related health conditions. This funding opportunity encourages applicants to submit Letters of Intent prior to full application deadlines. Key submission dates for standard and renewal applications span from February 2025 to October 2026, ensuring a wide array of research topics can be addressed.
Aging / Gerontology Diversity, Equity & Inclusion

Live Más Scholarship

Taco Bell Foundation Inc
Private
United States
Unspecified amount
The Live Más Scholarship, offered by the Taco Bell Foundation, supports students aged 16-26 pursuing higher education and workforce readiness. Emphasizing passion and impact, applicants showcase how their interests drive positive change in their communities. The foundation is dedicated to breaking down educational barriers, fostering creativity across various fields including arts, technology, and entrepreneurship. This initiative empowers young dreamers to turn their aspirations into actionable goals, creating meaningful contributions to society.
Education - Higher Education Vocational & Trade Education Career / College Preparation +2 more

Simons Dissertation Fellowship in Mathematics

Simons Foundation Inc.
Private
United States
Up to US $38,400
The Simons Dissertation Fellowship in Mathematics, offered by the Simons Foundation, supports exceptional Ph.D. students in their final years of study. This fellowship, honoring co-founder Jim Simons, provides $19,200 annually for research support and departmental funds, commencing September 1, 2025. Eligible candidates must be full-time Ph.D. students in a U.S. mathematics department, entering their third year. The program emphasizes research quality, significance, and potential impact.
Mathematics

Healing Illinois

Illinois Department of Human Services
State/Local Government
Illinois
Up to US $40,000
Healing Illinois, led by the Illinois Department of Human Services, is granting over $4.3 million to nonprofits for the 2025-2026 cycle, focusing on fostering racial and community healing. Since 2020, the program has supported healing initiatives across Illinois, engaging thousands in transformative projects that emphasize storytelling, dialogue, and the reclamation of community spaces. With an aim to reach over 20,000 residents in 30 counties, this initiative promotes resilience and connection among diverse communities.
Diversity, Equity & Inclusion Racial / Ethnic Justice & Rights

Betsy & Ryan Colwell Mentorship Scholarships for Women in Thoracic Surgery

The Thoracic Surgery Foundation
Private
Canada, Mexico +1 more
Up to US $2,500
The Betsy & Ryan Colwell Mentorship Scholarships for Women in Thoracic Surgery support early-career female cardiothoracic surgeons by facilitating mentor relationships and networking opportunities at the WTS Annual Conference. Each scholarship, valued at $2,500, covers conference registration, lodging, and travel expenses. Two scholarships will be awarded annually starting in 2025, aiming to empower women in a specialty where they are underrepresented and help them navigate their challenging career path.
Cardiovascular Diseases & Systems Surgery

CLG - Certified Local Government Grants Program

Illinois Department of Natural Resources
State/Local Government
Illinois
Up to US $30,000
The Certified Local Government Grants Program in Illinois supports city and county governments in developing local preservation projects. Funded by federal resources from the National Park Service, this program ensures at least 10% of Illinois’ federal allocation is dedicated to participating Certified Local Governments (CLGs). With 81 CLGs currently involved, the Illinois Department of Natural Resources anticipates $110,000 to $150,000 in competitive grants for this round, fostering the preservation of historic resources.
Historic Preservation

State Planning Funds

Illinois Department of Transportation
State/Local Government
Illinois
Unspecified amount
The State Planning Funds, provided by the Illinois Department of Transportation, aim to enhance statewide transportation planning activities. These funds establish a cooperative framework for making informed transportation investment decisions. Eligible entities must register and pre-qualify through the GATA Grantee Portal, ensuring compliance with federal regulations. This initiative supports comprehensive planning efforts across the state, fostering efficient transportation systems and infrastructure improvements.
Public Transportation & Mass Transit Systems

Macon County Grants for Nonprofits Highlights

Looking for Macon County grants for nonprofits?


Read more about each grant below or start your 14-day free trial to see all Macon County grants recommended for your specific programs in Illinois.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Grant Funding Trends in Illinois

Average Grant Size

What's the typical amount funded for Illinois?

Grants are most commonly $104,222.

$104,222

Total Number of Grants

What's the total number of grants in Macon County Grants for Nonprofits year over year?

In 2024, funders in Illinois awarded a total of 104,158 grants.

2022 97,582

2023 97,805

2024 104,158

Top Grant Focus Areas

Among all the Macon County Grants for Nonprofits given out in Illinois, the most popular focus areas that receive funding are Education, Philanthropy, Voluntarism & Grantmaking Foundations, and Human Services.

1. Education

2. Philanthropy, Voluntarism & Grantmaking Foundations

3. Human Services

Funding Over Time

How is funding for Macon County Grants for Nonprofits changing over time?

Funding has increased by 16.08%.

2022 $8,503,243,276

2023 $9,316,300,812
9.56%

2024 $10,813,952,832
16.08%

Illinois Counties That Receive the Most Funding

How does grant funding vary by county?

Cook County, Lake County, and Macon County receive the most funding.

County Total Grant Funding in 2024
Cook County $6,893,460,213
Lake County $720,580,526
Macon County $544,478,272
Champaign County $541,704,331
Dupage County $496,099,366

Related Grants in Illinois

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