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Best Large Grants for Nonprofit Organizations in Massachusetts

Find the perfect Large Grants for Nonprofit Organizations in Massachusetts on Instrumentl. 10,000+ Large Grants for Nonprofit Organizations in Massachusetts in the United States.

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$2.65B

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$5K

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$2.65B total
$5K median

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Basic Field Grant

Legal Services Corporation
Private
American Samoa, District of Columbia +6 more
Approximately US $20,000
LSC’s Basic Field Grants aim to enhance access to civil legal services for low-income individuals across the U.S. and territories. These grants support eligible organizations for up to three years through a competitive application process. The funding is allocated to specific service areas, which change annually, and focuses on providing comprehensive legal assistance. The program includes three types of service areas, ensuring diverse populations, including agricultural and Native American communities, receive necessary legal support.
Minority Services Legal Services Native American Services

T.E.A.L. Research Grant

Tell Every Amazing Lady About Ovarian Cancer Foundation
Private
United States
Up to US $20,000
The T.E.A.L. Research Grant supports innovative ovarian cancer research initiatives aligned with the mission of the Tell Every Amazing Lady About Ovarian Cancer Foundation. Designed for researchers affiliated with 501(c)3 not-for-profit institutions in the U.S., the grant aims to enhance women's health awareness and education regarding ovarian cancer. While the application period for 2025 is currently closed, interested parties should anticipate further updates in spring 2026.
Gynecological Cancers

Technologies for Improving Minority Health and Eliminating Health Disparities (R41/R42- Clinical Trial Optional) (352883)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
United States
Up to US $2,352,688
The Technologies for Improving Minority Health and Eliminating Health Disparities (R41/R42) program invites small business concerns to develop innovative technologies aimed at enhancing minority health and addressing health disparities. This initiative emphasizes the creation of effective, affordable, and culturally acceptable solutions for NIH-defined populations. Key deadlines for applications span from June 2024 to December 2026, with optional Letters of Intent encouraged 30 days prior to submission.
Minority Services Health Disparities & Social Determinants of Health Medical Technology, Devices, and Equipment

George F. and Asha W. McMillan Scholarship

Community Foundation of Henderson County
Private
United States
US $1,250

Community Foundation of Henderson County

Community Foundation of Henderson County was incorporated in 1982 by a group of fourteen dedicated and compassionate local leaders with the immediate need to manage two funds - the William C. Armstrong Scholarship Fund and the Charlie Renfrow Scholarship Fund, in addition to providing a permanent vehicle for citizens to give back to their community.

Our Mission is to help people who care make lasting contributions to causes that matter. The Community Foundation of Henderson County is a highly visible, philanthropic leader directed by an engaged and committed board, staffed by qualified employees, empowering donors at all levels to invest in professionally managed charitable funds that address community needs.

George F. and Asha W. McMillan Scholarship

This scholarship is to provide financial support to an individual in order for him or her to receive a degree in Christian education or related studies or to advance his or her Christian vocation.

Academic Scholarship Programs Christian Science Career / College Preparation

Innovations for Healthy Living - Improving Minority Health and Eliminating Health Disparities (R43/R44 - Clinical Trial Optional) (352882)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
United States
Up to US $2,352,688
The Innovations for Healthy Living program invites eligible U.S. small businesses to apply for SBIR grants aimed at improving minority health and eliminating health disparities. The initiative encourages innovative proposals for effective, affordable, and culturally acceptable solutions. Key deadlines for applications span from June 2024 to December 2026, with optional Letters of Intent recommended 30 days prior to submission. This funding opportunity supports projects that address health challenges faced by underserved populations.
Minority Services Health Disparities & Social Determinants of Health Medical Technology, Devices, and Equipment

Anderson Foundation for Autism Grant

Anderson Foundation for Autism Inc
Private
United States
Up to US $50,000
The Anderson Foundation for Autism Grant supports organizations aiming to enhance the quality of life for individuals with autism. Grants of up to $50,000 are available for qualified 501(c)(3) organizations, enabling them to implement impactful programs. The foundation not only funds its own initiatives but also extends support to other entities dedicated to similar goals. This initiative emphasizes a collaborative approach to improving autism care and support.
Autism

Mary V. Insall Scholarship

Nurses Educational Funds Inc.
Private
United States
Unspecified amount

Nurses Educational Funds

Nurses Educational Funds, Inc. depends solely on donations to advance our only mission, to promote nursing leadership through annual scholarship support for professional nurses seeking masters and doctoral degrees in nursing education, practice, research, and administration.

NEF’s only purpose is to provide nursing scholarship assistance to make graduate level nursing education possible. NEF is one of the largest, national, private, professionally endorsed source of funds for advanced nursing study with over one hundred years of service to and for professional nursing. NEF is a non-profit organization with 501(c) status.

Mary V. Insall Scholarship

The Mary Insall Scholarship was established in 2021, the result of a generous donation of $50,000 from Mary V. Insall, to recognize nurses interested in advanced practice, research and education in adult health, orthopedic specialization, and rehabilitation nursing at the Master’s and/or Doctoral level. This focus represents a keen interest by Ms. Insall in the field of orthopedics through her longtime affiliation with the Hospital for Special Surgery in New York City and therefore preference will be given to this area of specialty practice, research, and education.

Education - Higher Education Nursing Orthopedics

Domestic Violence Prevention: Forensic Healthcare Services

US Dept. of Health & Human Services: Indian Health Service
Federal Government
United States
Unspecified amount
The Domestic Violence Prevention grant aims to enhance access to forensic healthcare services for American Indian and Alaska Native victims of domestic violence and related issues. By fostering multidisciplinary partnerships, this initiative promotes trauma-informed care and improves victim support across IHS Areas. The focus is on developing comprehensive, culturally sensitive services that ensure timely interventions and coordinated responses to vulnerable populations, thereby enhancing overall victim well-being and safety.
Domestic Violence Crime Victim Services Violence Prevention +1 more

ACS Award for Encouraging Women Into Careers in the Chemical Sciences

American Chemical Society
Association/Society
United States
Up to US $16,500
The ACS Award for Encouraging Women Into Careers in the Chemical Sciences recognizes individuals who promote women's interests in chemistry, fostering their professional development. The award includes a $5,000 cash prize, a certificate, and a $10,000 grant to an academic institution designated by the recipient. Additionally, up to $1,500 for travel expenses to the award presentation will be reimbursed. This initiative highlights the importance of diversity in the chemical sciences and supports women's career advancement.
Chemistry Women's Rights & Equality Diversity, Equity & Inclusion +1 more

Our Village Grants

Jack And Jill Of America Foundation Inc
Private
United States
Up to US $10,000
The Our Village Grants by the Jack and Jill of America Foundation aim to support 501(c)(3) non-profit organizations dedicated to uplifting African American families. These grants focus on programs that address educational and economic disparities, particularly those exacerbated by the pandemic. Initiatives may include digital learning resources, tutoring, and support for health and food security. The foundation prioritizes organizations that align with their mission to create lasting positive impacts in under-resourced communities.
Racial / Ethnic Justice & Rights Black American Services

Marlene Schoenberger Scholarship

Community Foundation for Mason County, MI
Association/Society
United States
Unspecified amount

Community Foundation for Mason County, MI

The mission of the Community Foundation is to engage donors and connect them with opportunities to make a lasting impact, build community endowment, provide leadership on key issues, and make grants that reflect the communities we serve.

Scholarships

If you’re a high school or homeschooled senior, current college student, early college senior, or a student pursuing a master’s or doctoral degree, the Community Foundation for Mason County may have a scholarship for you.

Marlene Schoenberger Scholarship

This scholarship has been made possible by the generosity of Tamar Schoenberg, who established the Marlene Schoenberger Scholarship Fund of the Community Foundation for Mason County in memory of her mother, Marlene. This scholarship is presented to Mason County students pursuing Fine Arts and Performing Arts.

Education - Higher Education Performing Arts Fine Art

AGA: Caroline Craig Augustyn & Damian Augustyn Award in Digestive Cancer

American Gastroenterological Association
Association/Society
Canada, Mexico +1 more
US $40,000
The AGA: Caroline Craig Augustyn & Damian Augustyn Award in Digestive Cancer offers $40,000 for one year to early career investigators holding a career development award focused on digestive cancer research. This grant aims to support innovative studies in pathogenesis, prevention, diagnosis, and treatment. Applicants must provide evidence of their current awards, a recommendation letter, and demonstrate how the AGA funding will facilitate their transition to independence in research.
Gastrointestinal Cancers

Owen C. Meadows and Brenda J. Meadows Scholarship

Beckley Area Foundation
Private
United States
Unspecified amount

Beckley Area Foundation

Beckley Area Foundation was established in January 1985 by ten community-minded citizens. It began with a gift of $1.1 million from the Dr. Thomas Walker Memorial Health Foundation as “seed” money for this Raleigh County project. BAF assets have grown to over $70 million with over 500 different funds managed by our three trustee banks. Today, Beckley Area Foundation is one of West Virginia’s largest community foundations.

Since its inception, BAF has distributed over $23 million to charities and other worthy projects in the fields of education, public recreation, health & human services, the arts, animal services and beautification.

Scholarships

The Beckley Area Foundation proudly manages scholarship funds established by individuals, businesses, and organizations dedicated to helping students pursue higher education. Many of these scholarships are tailored for specific schools, fields of study, or graduates from local high schools, while others offer broader opportunities. No matter the path, our scholarships aim to support students from our region as they work toward achieving their educational goals.

Most of these scholarships must be awarded to students from our geographic area or at least preference given to such students. While the majority of scholarships benefit Raleigh County applicants there are others designated for Fayette, Summers, Webster, and Wyoming students. 

Owen C. Meadows and Brenda J. Meadows Scholarship

Must be resident of Raleigh County; Pursuing an accredited nursing program (including technical, baccalaureate or advanced nursing education programs); Merit and need based.​

This scholarship is not renewable.

Education - Higher Education Nursing Vocational & Trade Education

Joseph G. Markoly Foundation Grant Support for Children’s Organizations

Joseph G Markoly Foundation Inc
Private
United States
Unspecified amount

Joseph G Markoly Foundation Inc

When Joseph Markoly originally established the foundation more than thirty years ago, its focus was on Alzheimer’s and heart disease support, funded through a number of the larger national disease-related organizations. Over time the focus has shifted to helping small to mid-size organizations in our local communities which support children and seniors in a variety of effective ways. 

Markoly Foundation was established in honor of Joseph G. Markoly, an entrepreneur and philanthropist who wanted to make a positive impact in people’s lives. Joseph’s family was affected directly by both Alzheimer’s and heart disease having lost a family member to each condition. For that reason, the foundation dedicates a majority of their resources to providing grants to organizations that focus on the treatment of each of these diseases. In addition, Markoly Foundation supports a variety of programs dedicated to helping children and seniors by providing services, supplies, programs and research in areas impacting these demographics.

Joseph G. Markoly Foundation Grant Support for Children’s Organizations

Children are the future of this world and the Markoly Foundation is proud to fund local programs dedicated to improving the lives of children and their families. From providing vision services for school kids to classes on parenting, we are proud to do our part to help fund critical community programs for families.

We are dedicated to providing funding for local nonprofit programs that improve the quality of life for all, but particularly for the children and elders in our community.

Family Services Child Welfare Services Child Care Services

CAO Legislative Crisis Grant

National Education Association Staff Organization
Private
United States
Unspecified amount
The CAO Legislative Crisis Grant, funded by the National Education Association Staff Organization, is designed to support affiliates in creating and refining student-centered initiatives. Grants can be utilized for contract campaigns, new program development, or enhancing existing practices to improve sustainable learning conditions. This opportunity is exclusive to affiliates, ensuring a focused approach to advocacy and collective bargaining efforts that benefit students.
Education - K through 12 Education System Policy & Reform Educational Access & Equity

Joseph James Scholarship

10000 DEGREES
Private
United States
Up to US $1,500
The Joseph James Scholarship, managed by 10,000 Degrees, offers support to students from Bayside Martin Luther King Jr. Academy who graduated between 2013 and 2019. Eligible candidates can receive funding for up to two years, depending on their attendance duration. This scholarship aims to combat educational segregation and provides recipients with access to vital internship opportunities, enhancing their career readiness and skill development in various fields.
Career / College Preparation College Success / Persistence

Community Collaboration Challenge

National Partnership for Student Success
Association/Society
United States
US $5,000 - US $10,000

Community Collaboration Challenge

Applications for the 2026 Community Collaboration Challenge are now open! With support from the Leon Lowenstein Foundation, the Challenge provides $5,000 – $10,000 awards to communities and is designed to support collaboration that expands and pilots evidence-based K-12 student supports in the form of high-impact tutoring, mentoring, student success coaching, postsecondary transition coaching, and/or wraparound/integrated student supports.

Tutoring & Mentoring College Success / Persistence

Igor Gorin Memorial Award

Community Foundation for Southern Arizona
Private
United States
Up to US $12,000
The Igor Gorin Memorial Award, established in 1993 by the Community Foundation for Southern Arizona, honors the legacy of Igor Gorin by supporting aspiring vocalists. With $382,000 awarded to 49 young talents, this fund provides unrestricted financial assistance for coaching, travel, and auditions. The 2026 award offers up to $12,000, aimed at those overcoming financial barriers to pursue operatic careers, ensuring that exceptional vocalists can thrive in their artistic journeys.
Opera

Ida Halpern Fellowship and Award

Society for Ethnomusicology
Private
Canada, United States
US $5,000
The Ida Halpern Fellowship and Award, offered by the Society for Ethnomusicology, supports research on Native American music in the U.S. and Canada. Established scholars, recent Ph.D.s, and Ph.D. candidates are eligible, while previous awardees must wait three years to reapply. The fellowship includes a $4,000 grant and a $1,000 award for published research, with preference given to studies based on Dr. Halpern's Northwest Coast music collection.
Music Native American Culture & Heritage

Edward A. and Shirley B. Livi Scholarship Fund

Community Foundation of Western Massachusetts
Private
United States
Up to US $3,000

The Community Foundation of Western Massachusetts administers over 160 scholarships. Some of the funds help students from a particular school or area; others provide financial assistance to those pursuing a specific field of study; still others assist students that are most in need. Students who apply to the Scholarship program may be eligible for many of these funds. 

Scholarships are provided for one academic year and are not automatically renewed each year. You can reapply to our program every year you are going to attend college, and the application you submit that year will be considered for all scholarships for which you are eligible.

Edward A. and Shirley B. Livi Scholarship Fund

To support residents of Franklin, Hampden and Hampshire Counties who are pursuing fine or performing arts beyond their college freshman year.

Additional Guidelines

  • Students can receive up to $3,000 in scholarships from the Community Foundation.
  • Scholarship awards could impact the financial aid offered by a college, and students are advised to check with their college financial aid offices about this.
  • Scholarships may be used to offset tuition, fees, room and board, and other items included as part of the cost for attending the institution. Some part and/or all the award could be considered taxable income. It is advisable students check with the college or tax accountant regarding this matter.
Education - Higher Education Performing Arts Fine Art

Bonnie & Printis Shelton Scholarship

Community Foundation of Madison and Jefferson County
Private
United States
Up to US $7,000

In 2025, the Community Foundation of Madison & Jefferson County awarded over $233,000 in scholarships to graduating seniors of the county’s public and private high schools. Nearly 50 different students earned money toward their college costs. Scholarships are available for a variety of applicants. Some are specific to schools, majors, need, or interests.

CFMJC scholarships may be used for tuition and related expenses like fees and required equipment at accredited colleges and universities. Room and board are not covered.

Bonnie & Printis Shelton Scholarship

Criteria evaluated:

  • Academic achievement, extracurricular activities, and financial need

Required materials:

  • FAFSA SAI PDF upload

Scholarship amount:

  • $7,000 | 1 scholarship, renewable at $3,500 in each freshman & sophomore years
Education - Higher Education Vocational & Trade Education Career / College Preparation

NIDCR Drug, Biologic, Device and/or Procedure Intervention Clinical Trial Planning and Implementation Cooperative Agreement (UG3/UH3 Clinical Trial Required)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NIDCR Drug, Biologic, Device and/or Procedure Intervention Clinical Trial Planning and Implementation Cooperative Agreement (UG3/UH3) is designed to support clinical trial planning and implementation for dental, oral, and craniofacial conditions. This funding opportunity encourages applications that propose innovative research strategies within the NIDCR mission. Key deadlines span from February 2025 to January 2028, with emphasis on milestone-driven planning phases leading into possible clinical trial phases.
Dental Health Pharmacology Drug Safety +1 more

WAEF Scholarships - Danna Gebbers Guzman Memorial

Washington Apple Education Foundation
Private
United States
Unspecified amount
The WAEF Scholarships, supported by the Washington Apple Education Foundation, offer over $1 million in educational awards to more than 300 students this year. These scholarships are primarily for individuals with ties to the tree fruit industry in Washington, with a special focus on the Danna Gebbers Guzman Memorial Scholarship, aimed at nursing students. Eligible recipients can use the funds at accredited institutions with nursing programs.
Agricultural Crops Nursing

Breanna Lemler Scholarship

Marshall County Community Foundation Inc
Private
United States
Unspecified amount

Connecting Passion to Purpose

Marshall County Community Foundation is a public charity where local roots help great ideas take flight. We are community-minded partners and trusted investors. We help shape the vision for Marshall County. Our passion is to connect caring people with opportunities to make an impact.

Our mission is to serve all of Marshall county — its people and its future — by growing and managing endowment funding and fostering philanthropy.

Investing in the Scholars of 
Marshall County

Marshall County Community Foundation administers a number of scholarships, from traditional awards for graduating seniors to those geared towards current students, professionals, and other special circumstances.

Each scholarship has its own application guidelines, deadlines, and application process, so please be sure to read the instructions of the scholarship you’re applying for carefully.

All Marshall County Scholarships

We administer a number of scholarships, which range from the traditional academic and athletic awards to corporate and special circumstances offerings. These scholarships are open to all residents of Marshall County, as long as other requirements are met.

Applying for a scholarship is free, so we invite you to spend some time finding opportunities for which you are a good fit. You can learn more about each scholarship by clicking on each of the below scholarship titles.

Provides one or more annual scholarships to Marshall County high school seniors — specifically students graduating from Argos Community Schools, Bremen Public Schools, Culver Community Schools, John Glenn School Corporation, Plymouth Community Schools, Triton Community Schools or Union-North United School Corporation. 

Include a 250 word maximum essay including background, educational goals and any other information that might be helpful to the scholarship committee.

Education - Higher Education Sports & Athletics Agricultural Education

Glenn D. and Bennie Lou Hammons Family Scholarship

Central Kentucky Community Foundation
Private
United States
Unspecified amount
The Glenn D. and Bennie Lou Hammons Family Scholarship, established by the Central Kentucky Community Foundation in 1960, supports residents of Hardin County with a GPA between 2.5 to 3.5. This scholarship aims to empower local students by providing financial assistance for their educational pursuits, fostering community growth and development. As part of the Lincoln Trail Region's extensive network of community foundations, it reflects a commitment to enhancing educational opportunities for deserving applicants.
Education - Higher Education Education - High School Academic Scholarship Programs

MOORE Equity in Mental Health Community Grants Program

American Psychiatric Association Foundation
Private
United States
US $10,000
The MOORE Equity in Mental Health Community Grants Program, initiated by the American Psychiatric Association Foundation, aims to enhance mental health services for young people of color. With grants up to $10,000 over two years, it supports community organizations addressing mental health and substance use inequities. Eligible applicants include non-profits with a focus on culturally relevant care and sustainable solutions. The program fosters collaboration and awareness through innovative initiatives aimed at improving access to essential mental health services.
Mental Health & Psychiatric Diseases Addiction & Substance Use Disorders Health Care Access & Delivery

Stanley Fahn Junior Faculty Award

Parkinson's Foundation Inc.
Private
Canada, United States
US $300,000
The Stanley Fahn Junior Faculty Award, offered by the Parkinson's Foundation, supports early-career scientists in Parkinson's research. With $300,000 in funding over three years, it aims to bridge the gap for junior faculty transitioning to independent research. Eligible applicants must hold a PhD or MD and be U.S. or Canadian faculty members. This award promotes innovative research proposals that advance understanding and treatment of Parkinson's disease, fostering the next generation of scientists in this critical field.
Parkinson’s Disease

Large Grants for Nonprofit Organizations in Massachusetts Highlights

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Grant Insights : Large Grants for Nonprofit Organizations in Massachusetts

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

200+ Large Grants for Nonprofit Organizations in Massachusetts grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

95 Large Grants for Nonprofit Organizations in Massachusetts over $25K in average grant size

75 Large Grants for Nonprofit Organizations in Massachusetts over $50K in average grant size

60 Large Grants for Nonprofit Organizations in Massachusetts supporting general operating expenses

200+ Large Grants for Nonprofit Organizations in Massachusetts supporting programs / projects

3,000+ Grants on Instrumentl focused on Education

600+ Grants on Instrumentl focused on Food Access & Hunger

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Large grants for Nonprofit Organizations in Massachusetts?

Most grants are due in the first quarter.

Q1
32.0%
Q2
24.4%
Q3
18.8%
Q4
24.8%

Typical Funding Amounts

What's the typical grant amount funded for Large Grants for Nonprofit Organizations in Massachusetts?

Grants are most commonly $26,875.

$250 $250 Min.
$26,875 $26.9 K Median
$413,560 $413.6 K Average
$40,331,313 $40.3 M Max.

Average Grant Size

What's the typical amount funded for Massachusetts?

Grants are most commonly $124,010.

$124,010

Total Number of Grants

What's the total number of grants in Large Grants for Nonprofit Organizations in Massachusetts year over year?

In 2024, funders in Massachusetts awarded a total of 105,825 grants.

2022 103,608

2023 102,118

2024 105,825

Top Grant Focus Areas

Among all the Large Grants for Nonprofit Organizations in Massachusetts given out in Massachusetts, the most popular focus areas that receive funding are Education, Philanthropy, Voluntarism & Grantmaking Foundations, and Human Services.

1. Education

2. Philanthropy, Voluntarism & Grantmaking Foundations

3. Human Services

Funding Over Time

How is funding for Large Grants for Nonprofit Organizations in Massachusetts changing over time?

Funding has increased by 9.89%.

2022 $14,522,602,699

2023 $11,906,472,240
-18.01%

2024 $13,083,681,605
9.89%

Massachusetts Counties That Receive the Most Funding

How does grant funding vary by county?

Suffolk County, Middlesex County, and Norfolk County receive the most funding.

County Total Grant Funding in 2024
Suffolk County $7,016,988,269
Middlesex County $2,770,808,615
Norfolk County $554,651,103
Essex County $369,041,706
Worcester County $299,030,165