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Best Large Grants for Nonprofit Organizations in Massachusetts

Find the perfect Large Grants for Nonprofit Organizations in Massachusetts on Instrumentl. 10,000+ Large Grants for Nonprofit Organizations in Massachusetts in the United States.

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$2.65B

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$5K

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$2.65B total
$5K median

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CART Fund Grant

CART Fund
Private
United States
Up to US $500,000
The CART Fund Grant supports innovative Alzheimer’s Disease research projects in the U.S. with funding up to $500,000 for a two-year period. It invites full-time faculty from public and private institutions to submit Letters of Intent, emphasizing novel concepts that advance biomedical knowledge. Selected finalists will be invited to apply for standard grants. The initiative aims to foster groundbreaking research initiatives lacking extensive preliminary data, ensuring a focus on projects with transformative potential.
Dementia & Alzheimer’s Disease

Artemas Stearns Trust Grant

Artemas W Stearns Trust c/o Marsha E Rich ESQ
Private
Essex County, Massachusetts
Unspecified amount
The Artemas Stearns Trust Grant supports projects aimed at assisting the indigent elderly and deserving poor in Lawrence, Massachusetts. Organizations applying must demonstrate a direct benefit to these populations. However, the trust does not fund individuals, endowments, capital campaigns, or construction projects. This targeted approach ensures that the funds contribute effectively to the welfare of vulnerable community members.
Aging / Gerontology Poverty Alleviation & Services Indigenous Services

Walker Family Scholarship

Beckley Area Foundation
Private
United States
Unspecified amount

Mission Statement

Beckley Area Foundation exists to inspire and facilitate generous charitable giving that advances our community.

The Beckley Area Foundation is committed to enriching lives and strengthening communities across Southern West Virginia.

Scholarship

Supporting Student Success

The Beckley Area Foundation proudly manages scholarship funds established by individuals, businesses, and organizations dedicated to helping students pursue higher education. Many of these scholarships are tailored for specific schools, fields of study, or graduates from local high schools, while others offer broader opportunities. No matter the path, our scholarships aim to support students from our region as they work toward achieving their educational goals.

Walker Family Scholarship

Eligibility

Graduating Senior from a Raleigh County High School; Pursuing a degree in the arts; 3.0 GPA; Demonstrate both academic merit, and financial need.

Education - Higher Education Art Education Educational Access & Equity

Terence J. Centner Agricultural and Environmental 4-H Scholarship

Northern Chautauqua Community Foundation
Private
United States
Unspecified amount

Northern Chautauqua Community Foundation

Vision: We envision a vibrant, prosperous northern Chautauqua community, rich in opportunity today and tomorrow.

Our Mission

To realize our vision we focus on:

  • strategic and responsive grant making
  • encouraging local philanthropy and building permanent endowments for the future
  • actively serving as a community leader and partner for the benefit and enrichment in our community.

Scholarships

Northern Chautauqua Community Foundation proudly manages over 200 individual scholarship funds,

Terence J. Centner Agricultural and Environmental 4-H Scholarship

The Terence J. Centner Agricultural and Environmental 4-H Scholarship benefits student that participated in 4-H for a minimum of 3 years and completed an outstanding agricultural or environmental project.

This fund is established in memory of Harry E. and Mary Ellen Centner to honor their dedication and hard work on their family farm in the Town of Dunkirk and their leadership activities in the Chautauqua County 4-H Program.

Education - Higher Education Environmental Education Agricultural Education

Shirley Mudy Scholarship Fund

Crown Point Community Foundation
Private
United States
Unspecified amount
The Shirley Mudy Scholarship Fund, managed by the Crown Point Community Foundation, offers financial assistance for graduating high school seniors from Lake, Porter, Jasper, or Newton County. Eligible students must have a minimum 3.0 GPA, have participated in the Cedar Lake Girls Softball League or Riptide Travel Ball for at least four years, and plan to attend an accredited college, university, or trade school. An additional essay is required for application.
Education - Higher Education Vocational & Trade Education Baseball & Softball

Conservation Service Corps Grants

Great Outdoors Colorado
Private
Colorado, Countries
Unspecified amount
The Conservation Service Corps Grants, funded by Great Outdoors Colorado, support outdoor recreation and natural resource projects by hiring youth and veterans through conservation service corps. Annually, $1.5 million is allocated for these initiatives, enabling crews to tackle various projects like trail maintenance, invasive species mitigation, and wildlife habitat improvement. This program not only enhances natural resources but also provides job training and leadership skills to over 1,700 young participants each year.
Habitat & Ecosystem Restoration

Civic Engagement Microgrant Grant Program

Research!America
Private
United States
Up to US $4,000
The Civic Engagement Microgrant Grant Program, funded by Research!America, aims to enhance public engagement skills among early-career scientists. By providing financial support for innovative projects, this initiative encourages collaborations across various STEM disciplines. Grantees will develop essential skills in communication and policy-making to strengthen community ties and promote science as a national priority. This program addresses the critical need for scientists to connect with local communities and policymakers to ensure the relevance and impact of scientific research.
Science Communications STEM / STEAM Education Public Policy

NetVUE Grants for Fostering Leadership for Communities of Faith

The Council of Independent Colleges
Association/Society
United States
Up to US $60,000

Council of Independent Colleges (CIC)Founded in 1956, the Council of Independent Colleges (CIC) is an association of nonprofit independent colleges and universities, state-based councils, and higher education affiliates that works to support college and university leadership, advance institutional excellence, and enhance public understanding of independent higher education’s contributions to society.

CIC is the major national organization that focuses on providing services to leaders of independent colleges and universities and state-based councils. CIC offers conferences, seminars, publications, and other programs and services that help institutions improve educational quality, administrative and financial performance, student outcomes, and institutional visibility.NetVUE Grants for Fostering Leadership for Communities of FaithThis grant program provides funding for institutions that are working to augment their support for students who are considering possible callings to leadership roles in communities of faith.

Grant funds should be used to develop or extend programming for students, and/or professional development for faculty members and staff, with the goal of connecting students to local faith communities and supporting them as they explore and discern their callings. Initiatives may be developed within or across a variety of academic departments and campus offices, and should involve leaders of one or more faith communities near campus. NetVUE Grants for Fostering Leadership for Communities of Faith may be requested in amounts ranging up to $60,000 for use over two years to develop new programs, or to strengthen existing programs, that support students as they consider vocations of leadership for communities of faith.

Youth Development & Leadership Teacher Development & Training Religious / Theological Education

Child Well-Being National Program

Doris Duke Foundation Inc.
Private
United States
Unspecified amount
The Child Well-Being Grant Program, established by the Doris Duke Foundation, focuses on promoting the healthy development of children and preventing abuse. With a commitment to addressing systemic inequities, the program supports initiatives that strengthen social service systems and foster partnerships to enhance access to services. It prioritizes funding for projects that encourage community-based interventions and the development of future leaders dedicated to improving child welfare, ensuring all children have the opportunity to thrive in safe and supportive environments.
Child Welfare Services Early Childhood Development Child Abuse & Neglect

DDTSS Student Abstract Competition—Annual Meeting

Society of Toxicology
Association/Society
United States
US $150 - US $1,000
The DDTSS Student Abstract Competition, hosted by the Society of Toxicology, invites graduate students to submit abstracts for the Annual Meeting. Participants can win prizes of $1,000, $400, and $150 for the top three submissions. While SOT membership is encouraged, it is not mandatory. This competition fosters the importance of drug discovery toxicology and supports students in showcasing their research to a broader audience.
Environmental Chemistry & Toxicology

Dupont Alumni Scholarship

Community Foundation of Madison and Jefferson County
Private
United States
US $3,900

In 2025, the Community Foundation of Madison & Jefferson County awarded over $233,000 in scholarships to graduating seniors of the county’s public and private high schools. Nearly 50 different students earned money toward their college costs. Scholarships are available for a variety of applicants. Some are specific to schools, majors, need, or interests.

CFMJC scholarships may be used for tuition and related expenses like fees and required equipment at accredited colleges and universities. Room and board are not covered.

Dupont Alumni Scholarship

Criteria evaluated:

  • Academic record, interview, and financial need

Required materials: 

  • 2 letters of recommendation from teachers and/or counselors of the applicant’s high school; and 
  • FAFSA SAI PDF upload

Scholarship amount:

  • $3,900 | Multiple scholarships may be awarded
Education - Higher Education Vocational & Trade Education Career / College Preparation

Prader-Willi Syndrome Mini-Fellowship Grant ( up to $25,000)

Prader Willi Syndrome Association (Usa)
Private
United States
Up to US $25,000
The Prader-Willi Syndrome Mini-Fellowship Grant aims to enhance understanding of Prader-Willi Syndrome (PWS) through clinical proctorships. Offering up to $25,000 USD, this grant supports providers in shadowing experts in PWS while engaging in an academic project. PWSA | USA, dedicated to advancing research since 1983, focuses on high-impact projects that translate biomedical knowledge into effective treatments, ultimately improving the lives of those affected by PWS.
Endocrine & Metabolic Diseases Neurological Diseases & Disorders

Research & Development Grant

Chicken & Egg Pictures Inc
Private
United States
Up to US $20,000

About

Chicken & Egg Films shapes a more equitable and just world with the catalytic power of documentary films by providing funding, mentorship and industry access to a global community of women and gender-expansive filmmakers. Founded in 2005 by Julie Parker Benello, Wendy Ettinger, and Judith Helfand, and helmed today by CEO Jenni Wolfson, our goal is to disrupt and dismantle barriers to filmmaking caused by gender bias.

Research & Development Grant

Now in its fourth year, the Research & Development Grant supports filmmakers from around the world who have directed at least one feature-length documentary and are in the research & development stage of their next feature-length film.

With continued grant-making support by Netflix, the Research & Development Grant supports directors to ideate and plan for their next feature-length film. Many filmmakers invest their personal resources into their films and face funding challenges when entering into the research & development stages of new projects. It is hard to secure funding for a new project without significant sample material, yet producing material without external funding can be almost impossible. To address this challenge, the Research & Development Grant provides financial support to directors during a filmmaking stage that is too often unpaid and unsupported. 

A total of $450,000 USD will be awarded in the following grant amounts:

  • $10,000 USD grants for Research
  • $20,000 USD grants for Development

The final number of Research Grants vs. Development Grants disbursed will be determined during the selection process, based on the characteristics and strength of the applicant pool for each category.

The purpose of the Research & Development Grant is to support projects at the early stages of their lifecycle. If you have already raised a significant amount of capital (over 35% of your film’s total budget) and have shot and/or edited a substantial amount of footage, you may not be competitive for this grant, unless you can demonstrate very specific needs for the project (such as previously overlooked research activity). 

We have separated the Research Grant from the Development Grant to allow early-stage projects to receive support without the need to submit all the deliverables required for projects in the development phase. 

We recognize that each documentary is unique and that processes for research and development, fundraising, and production can vary widely. The information provided here is not intended as strict eligibility criteria, but rather as general guidelines to help applicants understand the stage at which we aim to provide support for projects. 

The 2026 Chicken & Egg Films Research & Development Grant is generously supported by Netflix.

Film Media Arts Visual Arts

Jacobs Engineering Group/AEESP Outstanding Doctoral Dissertation Award

Association of Environmental Engineering and Science Professors Foundation (AEESP Foundation)
Association/Society
United States
US $2,250
The Jacobs Engineering Group/AEESP Outstanding Doctoral Dissertation Award recognizes exceptional doctoral research that advances environmental science and engineering. Sponsored by the AEESP Foundation, this prestigious award includes a $1,500 prize for the student and $500 for their faculty advisor. Additionally, travel stipends are available for both recipients to attend the awards ceremony. Faculty advisors are encouraged to nominate deserving dissertations, with strict limits on submissions to ensure fairness and focus on high-quality research contributions.
Environmental Engineering Environmental Stewardship Academic Success & Enrichment

Grants for Independent Projects for Undergraduates

Weatherhead Center for International Affairs at Harvard University
Association/Society
Middlesex County, Massachusetts
US $250 - US $1,000
The Weatherhead Center for International Affairs at Harvard University provides grants of up to $1,000 for Harvard undergraduates to initiate programs focused on international affairs. These grants support activities like speaker series, special seminars, or conferences that enhance the undergraduate community's engagement with global issues. Eligible applicants include undergraduate organizations and student groups aiming to foster new initiatives. The Center prioritizes projects that do not receive other funding and encourages innovative ideas.
International / Foreign Affairs Cross-Cultural Understanding & Exchanges Public Policy +1 more

DDTSS Postdoctoral Abstract Competition—Annual Meeting

Society of Toxicology
Association/Society
United States
US $150 - US $1,000
The DDTSS Postdoctoral Abstract Competition, organized by the Society of Toxicology, invites postdoctoral researchers to present their accepted abstracts at the Annual Meeting. Open to applicants who have completed a PhD, the competition encourages submissions that highlight significant contributions to drug discovery toxicology. Awards of $1,000, $400, and $150 will be granted to the top three submissions. Membership in the Society is encouraged but not mandatory, fostering an inclusive environment for all participants.
Environmental Chemistry & Toxicology

AHS Investigator-Initiated Research Awards

American Headache Society (AHS)
Association/Society
United States
Up to US $50,000

American Headache Society

The American Headache Society (AHS) is a professional society of healthcare providers dedicated to the study and treatment of headache and face pain. The Mission of the AHS is to improve the lives of people impacted by migraine and other headache disorders. AHS advocates for those impacted by headache and the headache field, to meet our core objectives. AHS provides educational courses, scientific meetings, a journal, research support, career development opportunities, Special Interest Groups, advocacy training, and a professional community. The AHS strives to meet its objectives while fostering an inclusive sense of belonging and community.

AHS Investigator-Initiated Research Awards

Empowering Innovation in Headache Research

The American Headache Society (AHS) Investigator-Initiated Research Awards support AHS members conducting pre-clinical and clinical research in headache and migraine. With a focus on early-career investigators, the program funds investigator-driven projects that advance scientific understanding and improve patient care.

Projects should contribute to the core goal of the AHS – improving the lives of people impacted by migraine and other headache disorders. 

Funding may be used for:

  • Investigator effort (limited to 25% of the budget for PI salary support).
  • Experimental costs, data collection, supplies, and statistical analysis.
  • Other research-related expenses as appropriately justifie
Neurological Diseases & Disorders Chronic / Acute Pain

SETAC North America: Meeting Attendance Grants for Students

Society of Environmental Toxicology and Chemistry (SETAC)
Association/Society
North America
Unspecified amount
The SETAC North America Student Meeting Attendance Grant supports student participation in annual meetings, emphasizing inclusivity and excellence. This program provides waived registration and stipends for costs such as travel and dependent care. Eligible students can apply during abstract submission from March to May, with grants available for each degree program. The initiative encourages applicants from diverse backgrounds, particularly those from indigenous communities and minority-serving institutions, enhancing representation within the environmental sciences.
Environmental Chemistry & Toxicology

Mid-Dissertation Grants

Weatherhead Center for International Affairs at Harvard University
Association/Society
Middlesex County, Massachusetts
US $3,000 - US $4,000
The Weatherhead Center for International Affairs at Harvard University offers Mid-Dissertation Grants to support doctoral students conducting research aligned with its core interests. Designed for those who are post-prospectus and in the middle of their dissertation process, these grants provide $3,000–$4,000 for specific research needs, travel, or special projects. The Center emphasizes collaboration among scholars and supports diverse research topics related to international and comparative issues.
Public Policy International / Foreign Affairs Cross-Cultural Understanding & Exchanges +1 more

Pre-Dissertation Grants

Weatherhead Center for International Affairs at Harvard University
Association/Society
Middlesex County, Massachusetts
US $3,000 - US $4,000
The Pre-Dissertation Grants, offered by the Weatherhead Center for International Affairs at Harvard University, support doctoral students who are in the early stages of their research. These grants, ranging from $3,000 to $4,000, are specifically designed for Harvard graduate students who have passed preliminary exams and are beginning their dissertation work on topics related to international and comparative research.
International / Foreign Affairs Cross-Cultural Understanding & Exchanges Public Policy +1 more

Grants for Graduate Student Workshops and Conferences

Weatherhead Center for International Affairs at Harvard University
Association/Society
Middlesex County, Massachusetts
US $500 - US $1,500
The Weatherhead Center for International Affairs at Harvard University offers grants ranging from $500 to $2,500 to support graduate student-led workshops and conferences. These grants are specifically aimed at students presenting research related to international, transnational, and global issues. Applicants must be enrolled in a doctoral program and preference is given to those affiliated with the Center. This initiative encourages collaboration and the dissemination of impactful research.
International / Foreign Affairs Cross-Cultural Understanding & Exchanges Public Policy +1 more

Dissertation Writing Grants

Weatherhead Center for International Affairs at Harvard University
Association/Society
Middlesex County, Massachusetts
Approximately US $17,850
The Weatherhead Center for International Affairs at Harvard University provides Dissertation Writing Grants to aid advanced graduate students in their doctoral studies. These grants, up to eight at approximately $17,850 each, aim to relieve students of teaching duties for a semester, allowing them to concentrate solely on writing their dissertations. Eligibility is limited to students in the writing stage of their dissertation, particularly G4, G5, and G6 candidates, focusing on research aligned with the Center's interests.
International / Foreign Affairs Cross-Cultural Understanding & Exchanges Public Policy +1 more

NIH Research Software Engineer (RSE) Award (R50 Clinical Trials Not Allowed)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $300,000
The NIH Research Software Engineer (RSE) Award aims to provide salary support for outstanding Research Software Engineers who play a vital role in creating and sharing biomedical, behavioral, or health-related software and tools. This opportunity encourages RSEs to enhance the development of algorithms and support training for prospective users. Applications are due by 5:00 PM local time, with optional Letters of Intent recommended 30 days prior to the proposal deadline.
Health Information Technology Computer Science & Engineering Health & Medicine +1 more

High-End Instrumentation (HEI) Grant Program (S10 Clinical Trial Not Allowed) (356883)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
US $300,000 - US $5,000,000
The High-End Instrumentation (HEI) Grant Program, offered by the NIH, invites applications for purchasing or upgrading high-end, specialized instruments, with a minimum award of $750,001 and a maximum of $2,000,000. This program supports NIH investigators aiming to enhance their research capabilities through advanced technologies such as mass spectrometers and electron microscopes. Applications must be submitted by 5:00 pm local time of the applicant organization.
Medical Technology, Devices, and Equipment Health & Medicine Biotechnology +1 more

Robert C. Weaver Memorial Scholarship Fund

Idaho Community Foundation (ICF)
Private
United States
Unspecified amount

Idaho Community Foundation

The Idaho Community Foundation distributes millions annually in grants and scholarships across the state. These awards are made possible by individuals, families, businesses, affiliates, giving circles, and everyday Idahoans who care for their community.Robert C. Weaver Memorial Scholarship FundEstablished by Neola Weaver in memory of her late husband, residents or former residents of Buhl are eligible for scholarship support as either traditional or nontraditional students. For part-time or full-time traditional or nontraditional students pursuing post high school vocational or academic training. 

Education - Higher Education College Success / Persistence Vocational & Trade Education

National Fish Passage Program

US Department of the Interior: Fish and Wildlife Service (FWS)
Federal Government
United States
US $500 - US $2,000,000
The National Fish Passage Program (NFPP) offers technical and financial support to restore aquatic connectivity for fish and other organisms. By improving infrastructure like culverts and bridges, the program enhances fish populations and ecosystem resilience, providing quality fishing experiences. Managed by the US Fish and Wildlife Service, NFPP collaborates with partners to implement strategic projects that align with conservation goals, ensuring biological diversity and effective use of scientific principles in project planning.
Fisheries Fish Conservation

Pilot Projects Investigating Understudied Proteins Associated with Rare Diseases (R03 Clinical Trial Not Allowed) (356879)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $100,000
This funding opportunity invites applications for pilot projects focused on understudied proteins linked to rare diseases. The goal is to generate preliminary data and tools related to these proteins, which belong to druggable families with known rare disease associations. By supporting innovative research, this initiative aims to facilitate the characterization of these proteins, ultimately contributing to advancements in understanding and treating rare diseases.
Human Genome & Genetics Rare Diseases

Large Grants for Nonprofit Organizations in Massachusetts Highlights

Looking for large grants for nonprofit organizations in Massachusetts?


Read more about each grant below or start your 14-day free trial to see all large grants for nonprofit organizations in Massachusetts recommended for your specific programs.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Large Grants for Nonprofit Organizations in Massachusetts

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

200+ Large Grants for Nonprofit Organizations in Massachusetts grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

95 Large Grants for Nonprofit Organizations in Massachusetts over $25K in average grant size

75 Large Grants for Nonprofit Organizations in Massachusetts over $50K in average grant size

60 Large Grants for Nonprofit Organizations in Massachusetts supporting general operating expenses

200+ Large Grants for Nonprofit Organizations in Massachusetts supporting programs / projects

3,000+ Grants on Instrumentl focused on Education

600+ Grants on Instrumentl focused on Food Access & Hunger

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Large grants for Nonprofit Organizations in Massachusetts?

Most grants are due in the first quarter.

Q1
32.0%
Q2
24.4%
Q3
18.8%
Q4
24.8%

Typical Funding Amounts

What's the typical grant amount funded for Large Grants for Nonprofit Organizations in Massachusetts?

Grants are most commonly $26,875.

$250 $250 Min.
$26,875 $26.9 K Median
$413,560 $413.6 K Average
$40,331,313 $40.3 M Max.

Average Grant Size

What's the typical amount funded for Massachusetts?

Grants are most commonly $124,010.

$124,010

Total Number of Grants

What's the total number of grants in Large Grants for Nonprofit Organizations in Massachusetts year over year?

In 2024, funders in Massachusetts awarded a total of 105,825 grants.

2022 103,608

2023 102,118

2024 105,825

Top Grant Focus Areas

Among all the Large Grants for Nonprofit Organizations in Massachusetts given out in Massachusetts, the most popular focus areas that receive funding are Education, Philanthropy, Voluntarism & Grantmaking Foundations, and Human Services.

1. Education

2. Philanthropy, Voluntarism & Grantmaking Foundations

3. Human Services

Funding Over Time

How is funding for Large Grants for Nonprofit Organizations in Massachusetts changing over time?

Funding has increased by 9.89%.

2022 $14,522,602,699

2023 $11,906,472,240
-18.01%

2024 $13,083,681,605
9.89%

Massachusetts Counties That Receive the Most Funding

How does grant funding vary by county?

Suffolk County, Middlesex County, and Norfolk County receive the most funding.

County Total Grant Funding in 2024
Suffolk County $7,016,988,269
Middlesex County $2,770,808,615
Norfolk County $554,651,103
Essex County $369,041,706
Worcester County $299,030,165