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Best Minneapolis Grants for Nonprofits in Minnesota

Discover active funding opportunities in Minneapolis Grants for Nonprofits. 36,000+ grants are available for a wide range of missions and programs with additional grants in Saint Paul, Rochester, and Duluth.

10,000+

Available grants

$2.71B

Total funding

$5K

Median grant

10,000+ grants
$2.71B total
$5K median

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DOW Combat Readiness – Medical Research Program Translational Research Award

US DOD: U.S. Army Medical Command
Federal Government
American Samoa, Guam +4 more
Up to US $1,450,000
The DOW Combat Readiness – Medical Research Program's FY26 Translational Research Award supports innovative research aimed at improving trauma care outcomes. This program emphasizes hypothesis-driven studies that can transition promising technologies into practical solutions for enhancing casualty survivability. Applicants must provide preliminary data and utilize validated animal models, with a focus on projects that meet a minimum technology readiness level of 4, ensuring a mature translational research effort.
Crisis Intervention Post-Traumatic Stress Disorder

Improved Drug Susceptibility Testing (DST) for Mycobacteria

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Institute of Allergy and Infectious Diseases (NIAID) is funding research to enhance drug susceptibility testing (DST) for mycobacteria. This initiative aims to improve testing for tuberculosis (TB) and non-tuberculous mycobacterial (NTM) infections, which are on the rise. Current methods are slow and ineffective against drug-resistant strains, making rapid DSTs essential for effective treatment and reducing transmission rates. Innovative approaches, including rapid genotypic and phenotypic methods, will be supported to address these challenges.
Infectious & Parasitic Diseases Tuberculosis Drug-Resistant Bacteria

Powered & Prepared Initiative Grant

Hillman Family Foundations
Private
U.S. Territories, United States
US $300,000

About Henry L. Hillman Foundation

Henry L. Hillman Foundation inspires, invests in, and leverages great ideas to improve the quality of life in Pittsburgh and southwestern Pennsylvania.

Backup Power When Your Community Needs It

The Powered & Prepared Initiative seeks proposals from nonprofit and municipal organizations in southwestern Pennsylvania for backup power solutions that allow those organizations to offer essential services during emergencies without disruption.

Southwestern Pennsylvania is increasingly impacted by severe weather events that cause widespread power outages and disruptions. The Powered & Prepared Initiative, supported by Henry L. Hillman Foundation, seeks proposals from nonprofit and municipal organizations for backup power solutions that allow those organizations to offer essential services during emergencies without disruption.

Basic Human Needs Emergency Medical Care & Services Disaster Relief / Humanitarian Aid +2 more

Carol D. Garling Scholarship

Community Foundation of Washington County Maryland
Private
United States
Unspecified amount
The Carol D. Garling Scholarship, established by Carol D. Garling, provides financial assistance to students pursuing a post-secondary education who have completed at least 30 credit hours at an accredited institution. Offered by the Community Foundation of Washington County, MD, this scholarship is part of a larger initiative to support local students and promote educational advancement within the community. Applications are accepted annually from January to April 1st, encouraging both high school graduates and non-traditional students.
Education - Higher Education Vocational & Trade Education Academic Scholarship Programs

Bill Dorsey Memorial Scholarship Fund for Barbara Ingram School for the Arts

Community Foundation of Washington County Maryland
Private
United States
Unspecified amount
The Bill Dorsey Memorial Scholarship Fund, established by the Community Foundation of Washington County, MD, offers scholarships to students at the Barbara Ingram School for the Arts (BISFA). Designed for rising sophomores, juniors, and seniors, this fund helps cover costs related to their arts discipline. Applications are available in the Fall, supporting the foundation's mission to enhance educational opportunities for local students and nurture their artistic talents.
Education - Higher Education Vocational & Trade Education Academic Scholarship Programs

Hagerstown Garden Club Scholarship

Community Foundation of Washington County Maryland
Private
United States
Unspecified amount
The Hagerstown Garden Club Scholarship, administered by the Community Foundation of Washington County, supports Washington County residents pursuing education in horticulture. Eligible applicants include graduating high school seniors and current college students with a minimum GPA of 3.0. This scholarship honors the legacy of the Hagerstown Garden Club and is part of a broader initiative to enhance community life through educational opportunities, fostering both personal and professional growth in the horticultural field.
Education - Higher Education Vocational & Trade Education Academic Scholarship Programs +2 more

WaterSMART Cooperative Watershed Management Program

US Department of the Interior: Bureau of Reclamation (USBR)
Federal Government
American Samoa, Guam +4 more
US $50,000 - US $300,000
The WaterSMART Cooperative Watershed Management Program offers funding to eligible entities for developing local solutions to water management issues. This initiative supports watershed group development, restoration planning, and project design, promoting stakeholder cooperation and improving water reliability. It aligns with key priorities from the Trump administration, addressing complex water challenges and enhancing federal grant oversight. By facilitating these efforts, the program aims to stretch limited water resources and foster collaborative solutions among diverse stakeholders.
Habitat & Ecosystem Restoration Water Resource Management

NIAMS Clinical Trial Implementation Cooperative Agreement

National Institutes of Health
Federal Government
American Samoa, Guam +4 more
More than US $250,000
The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) is inviting applications for the Clinical Trial Cooperative Agreement Program. This funding opportunity supports investigator-initiated, interventional clinical trials at various phases. Initial funding will facilitate the preparation needed to start trials, with successful milestones leading to further support. NIAMS emphasizes hypothesis-driven trials that promise significant clinical impact within its research mission.
Musculoskeletal Diseases Arthritis Skin Diseases & Dermatology

Exploratory Clinical Trial Grants in Arthritis and Musculoskeletal and Skin Diseases

National Institutes of Health
Federal Government
American Samoa, Guam +4 more
US $300,000 - US $600,000
The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) is launching a funding opportunity for Exploratory Clinical Trials Grants. This program aims to support innovative clinical trials that enhance the understanding and treatment of arthritis and other musculoskeletal and skin conditions. Research proposals should focus on early-stage trials, including first-in-human studies, dose-finding, and biomarker evaluation. The initiative encourages the translation of promising laboratory findings into effective clinical practices, ultimately improving patient outcomes.
Musculoskeletal Diseases Skin Diseases & Dermatology Arthritis

Global Health, K-12 STEM Education and Economic Mobility Grant

Eli Lilly And Company Foundation
Private
United States
Unspecified amount

Lilly Foundation

To extend Lilly’s charitable reach and impact, the Eli Lilly and Company Foundation (Lilly Foundation) was established in 1968 and is supported by donations from Eli Lilly and Company.

The Foundation is a tax-exempt, private foundation supporting programs that align with its philanthropic priorities.

Grantmaking Approach

The Lilly Foundation’s work is guided by a charitable vision of a world where every person has an opportunity to live their healthiest life. Through grantmaking focused on Lilly Foundation’s charitable vision, grants can serve as a catalyst for closing gaps and empowering individuals and communities to thrive.

All proposals should demonstrate clear alignment with at least one focus area and include charitable outcomes that are measurable and consistent with the Foundation’s long-term charitable goals.

Global Health, K-12 STEM Education and Economic Mobility Grant

Focus Areas

Global Health

Lilly Foundation, through its charitable grants, aims to support permissible charitable efforts to improve access to quality healthcare for resource-limited communities in low- and lower-middleincome countries (L/LMICs) and in the United States. Strengthening access to care is essential for enhancing community well-being and supporting economic stability in resource-limited settings.

The Global Health focus area aims to close gaps in quality healthcare by supporting charitable solutions that improve access, bring care closer to where people live, and address the high burden of non-communicable diseases (NCDs) in resource-limited settings. To the extent permissible, the Foundation prioritizes charitable efforts related to cardiometabolic health in resource-limited settings.

K-12 STEM Education

The K-12 STEM Education focus area aims to close the gaps for students from low-income communities by supporting programs that foster new pathways and pipelines to STEM education through focused K-12 efforts, concentrating on the critical middle school years. The Foundation’s K-12 STEM Education grants are focused on initiatives that benefit Marion County, Indiana.

Economic Mobility

The Economic Mobility focus area supports charitable and educational programs that strengthen workforce readiness, postsecondary and skills-based educational pathways, and housing stability to promote long-term prosperity. This support is focused on Marion County, Indiana, with the goal of improving economic opportunity for low-income communities and advancing community well-being.

Health Disparities & Social Determinants of Health Community Health Education Nutrition & Healthy Eating +9 more

RFP- Address The Opioid Overdose Crisis In Communities And Populations

Minnesota Department of Human Services Behavioral Health Administration
State/Local Government
Minnesota
US $350,000
The Minnesota Department of Human Services, through its Behavioral Health Administration (STATE), is seeking Proposals from qualified Responders to address the opioid overdose crisis in communities and populations that have been historically underserved and disproportionately impacted by opioid-related overdose deaths. 
Addiction & Substance Use Disorders Drug Use Disorder

Zero Electrocution Challenge Grant

McElhattan Foundation
Private
U.S. Territories, United States
Up to US $1,000,000

About McElhattan Foundation

Founded in 2017 following the sale of Industrial Scientific Corporation, McElhattan Foundation invites bold ideas that advance the goals of its four program areas, including Ending Death on the Job.

Zero Electrocution Challenge

Despite decades of regulations, training, and personal protective equipment, workers continue to die from electrical contact every year.

McElhattan Foundation’s Zero Electrocution Challenge seeks breakthrough solutions that present pathways to eliminate life-threatening tasks that lead to fatal electrocution on the job by the year 2050, while increasing enterprise profitability and productivity. This is the inaugural ZERO 2050 challenge, awarding two Winners up to $1 million each.

Occupational Health & Safety Electrical Engineering

Special Program Announcement for Office of Naval Research Research Opportunity: FY27 Communications and Networking Applied Research

US DOD: Dept. of the Navy, Office of the Chief of Naval Research
Federal Government
United States
US $250,000 - US $500,000
The FY27 Communications and Networking Applied Research program aims to advance technologies essential for Naval operations. This initiative aligns with the Design for Maritime Superiority, focusing on the Naval Tactical Grid (NTG) to ensure seamless connectivity among distributed units. The technologies developed will operate under challenging conditions across multiple domains, enhancing command and control capabilities for effective decision-making in maritime and other operational theaters.
Military Operations Emerging Technology Development Cyberinfrastructure

Fair Housing Initiatives Program Private Enforcement Initiative (362827)

US HUD: Office of Fair Housing and Equal Opportunity (FHEO)
Federal Government
United States
US $250,000 - US $500,000
The Fair Housing Initiatives Program (FHIP) aims to combat discriminatory housing practices through funding provided to various organizations. Established by Congress in 1988 and made permanent in 1992, FHIP supports entities that educate the public and enforce fair housing rights. The program offers competitive grants across four initiatives, including the Private Enforcement Initiative, which enables national non-profit organizations to investigate violations and uphold fair housing laws effectively.
Civil Rights Real Estate & Housing Equitable & Affordable Housing +1 more

John A. Knauss Marine (and Great Lakes) Policy Fellowship

Wisconsin Sea Grant
State/Local Government
United States, United States Minor Outlying Islands
Unspecified amount

About Us

Wisconsin Sea Grant is a statewide program of basic and applied research, education, outreach and technology transfer dedicated to the stewardship and sustainable use of the nation’s Great Lakes and ocean resources.

Headquartered at the University of Wisconsin-Madison, the institute is housed in the Office of the Vice Chancellor for Research’s Aquatic Sciences Center. (See our Water and Land Acknowledgement.) Wisconsin Sea Grant is part of a national network of 34 university-based programs funded through the National Sea Grant College Program, National Oceanic and Atmospheric Administration, U.S. Department of Commerce and through matching contributions from participating states and the private sector. 

John A. Knauss Marine (and Great Lakes) Policy Fellowship

The University of Wisconsin Sea Grant College Program is accepting applications from graduate students statewide for the National Sea Grant College Program’s John A. Knauss Marine (and Great Lakes) Policy Fellowship Program. The program, established in 1979, provides a unique educational experience to applicants who have an interest in ocean, coastal and Great Lakes resources and in the national policy decisions affecting those resources. The program matches highly qualified graduate students with “hosts” in the legislative and executive branch of government located in the Washington, D.C. area, for a one year paid internship. Placement opportunities are numerous and very diverse and have typically included offices within Congress, the Executive Office of the President, the National Oceanic and Atmospheric Administration, the National Aeronautics and Space Administration, the U.S. Fish and Wildlife Service, the Environmental Protection Agency, the Federal Emergency Management Agency, the U.S. Navy, and the U.S. Departments of State, Treasury, Transportation, and Energy, in addition to others. Applicants from a variety of backgrounds including natural and social sciences, law, engineering, and communications can be competitive for this fellowship. Fellowships begin June 1, 2027.

Marine Biology Marine / Ocean Conservation

DoW Rare Cancers Concept Award

US DOD: U.S. Army Medical Command
Federal Government
American Samoa, Guam +4 more
Up to US $140,000
The DoW Rare Cancers Concept Award for FY26 promotes groundbreaking ideas in rare cancer research. This award encourages innovative applications that explore novel courses of investigation without requiring preliminary data. Unique to this program is the prohibition against mentioning the Principal Investigator or collaborators in the proposal materials, ensuring an unbiased review process. This funding opportunity aims to advance scientific discovery in the rare cancer domain.
Cancer / Oncology

Tribal Broadband Connectivity Program (362843)

DOC NIST ERA
Federal Government
United States
US $500,000 - US $25,000,000
The Tribal Broadband Connectivity Program (TBCP) aims to enhance broadband access and adoption on Tribal lands, supporting initiatives for remote learning, telework, and telehealth. Administered by NTIA, this program provides vital funding to eligible entities under the Consolidated Appropriations Act of 2021 and the Infrastructure Investment and Jobs Act of 2021. This funding is crucial for fostering digital inclusion and improving connectivity in underserved Tribal communities.
Native American Services Technology Access & Digital Literacy Cyberinfrastructure +1 more

Native Entities Grant Program

DOC NIST ERA
Federal Government
United States
US $500,000 - US $2,500,000
The Native Entities Grant Program, initiated by NTIA under the Digital Equity Act of 2021, aims to support Indian Tribes, Alaska Native entities, and Native Hawaiian organizations. This program streamlines funding through a unified application for two significant initiatives: the State Digital Equity Capacity Grant and the Digital Equity Competitive Grant. By focusing on reducing administrative burdens, it enhances access to digital resources and equity in underserved communities.
Native American Services Technology Access & Digital Literacy Indigenous Services

DoW Bone Marrow Failure, Idea Development Award

US DOD: U.S. Army Medical Command
Federal Government
American Samoa, Guam +4 more
Up to US $800,000
The DoW Bone Marrow Failure Idea Development Award supports innovative, high-impact research aimed at understanding and curing bone marrow failure diseases. This grant is available to both Established Investigators and Early-Career Investigators, with no preliminary data required for applications. Reviewers assess proposals based on specific criteria tailored to the investigator's career stage. The focus is on achieving interpretable results that contribute significantly to the field.
Skeletal Diseases Myeloma

DoW Bone Marrow Failure, Investigator-Initiated Research Award

US DOD: U.S. Army Medical Command
Federal Government
American Samoa, Guam +4 more
Up to US $1,250,000
The DoW Bone Marrow Failure Investigator-Initiated Research Award supports innovative research aimed at advancing the understanding and treatment of bone marrow failure. This funding opportunity encourages applications for translational and clinical studies, requiring preliminary data to strengthen proposals. Unique features include the ability for a partnering Principal Investigator to contribute to the research, thereby fostering collaboration while maintaining a focus on significant advancements in patient care.
Skeletal Diseases Myeloma

DoW Rare Cancers Idea Development Award

US DOD: U.S. Army Medical Command
Federal Government
American Samoa, Guam +4 more
Up to US $490,000
The DoW Rare Cancers Idea Development Award promotes innovative research ideas for rare cancers, encouraging applicants to provide preliminary data and exploratory aims. This funding opportunity, offered by the US DOD: U.S. Army Medical Command, seeks projects with the potential for high-impact findings that can significantly benefit the patient community. It aims to foster new avenues of investigation and support discovery-driven research in the field of rare cancers.
Cancer / Oncology

Building the Future Workforce Challenge Grant

Caterpillar
Corporate
Brazil, India +2 more
US $1,000,000

Building the Future Workforce Challenge

Awarding $5 million and the opportunity to test bold, tech‑forward solutions that strengthen the advanced manufacturing and industry technician workforce—today and for the future.

About the Challenge

Caterpillar knows preparing the workforce for the future is urgent. Communities, employers, and industry need new ways to close advancing skill gaps. The Building the Future Workforce Challenge invites fresh perspectives from all sectors to rethink training. Up to five teams will be awarded $1 million each for sustainable, tech‑forward solutions that strengthen today’s—and tomorrow’s—advanced manufacturing and industry technician talent pipelines.

What types of solutions are you looking for?

The Building the Future Workforce Challenge aims to identify, test, and scale innovative, sustainable solutions that will address today’s and tomorrow’s advanced manufacturing and industry technician skill gaps. A core requirement of any solution is that it remains relevant amid evolving technology—ensuring that breakthrough innovation and human potential rise together.

Strong proposals for Building the Future Workforce Challenge will meet four criteria outlined in the scoring rubric, and proposed solutions must focus on one or more of the following solution categories for Building the Future Workforce Challenge:

Workforce Preparation & Job Readiness Vocational & Trade Education Manufacturing Engineering +2 more

Pre-clinical Investigation of anti-TFPI-mediated Rebalancing Mechanisms in Non-Hemophilic Bleeding Disorders (2026-06-26)

Pfizer, Inc.
Corporate
Brazil, China +7 more
Up to US $50,000

Pre-clinical Investigation of anti-TFPI-mediated Rebalancing Mechanisms in Non-Hemophilic Bleeding Disorders 

There remains a scientific gap in understanding of the role of anti-TFP Imediated hemostatic rebalancing in the context of inherited or non-hemophilic bleeding disorders. This competitive grant program encourages competitive submissions focsed on generating preclinical/foundational data exploring the therapeutic potential and mechanisms of TFPI modulation in bleeding disorders other than hemophilia.

Geographic Scope

Brazil, China, Europe, Israel, Japan, Saudi Arabia, South Korea, Turkey, USA

Funding Range and Project Length

Individual projects requesting up to $50,000 USD will be considered.

Request for study drug or compound is allowed (max $50,000 USD), additionally to the study project costs.

Maximum project length is 1 year.

Hematological Systems

Pediatric Hidradenitis Suppurativa Challenge Grant

Pediatric Dermatology Research Alliance Inc
Private
United States
Up to US $50,000

Pediatric Hidradenitis Suppurativa Challenge Grant

Hidradenitis suppurativa (HS) is a devastating chronic inflammatory disease that manifests as recurrent painful nodules under the skin in the intertriginous areas of the body. It is associated with significant impacts on quality of life, psychosocial well-being, and long-term health outcomes of patients as well as consequences for families and caregivers. HS is prevalent, affecting between 1 and 4% of the population beginning in adolescence and persisting into adulthood. Despite the impact of HS, it remains underdiagnosed, undertreated, and understudied particularly in the pediatric and adolescent populations. Contributing to this dynamic are unknowns related to a complex disease etiology, stigma associated with HS symptoms (e.g., sweating, itching, and scarring commonly in the genital region), and limited treatment options to date with even fewer available for children under the age of 12.

To address the needs of children and adolescents living with HS, the Pediatric Dermatology Research Alliance (PeDRA), HS Connect, and the HS Foundation are offering the 2026 Pediatric HS Challenge Grant to support an early-to-mid career investigator for a one-year project focused on a high-priority, patient-centric research topic.

Focus

Proposals should address one or more of the following high-priority research topics:

  • Predicting treatment effectiveness and risk utilizing real world evidence and/or experience
  • Early disease and factors involved in severe disease development
  • Optimizing surgical and procedural approaches to minimize pain, shorten healing time, and reduce recurrence
  • Improving recruitment of diverse and representative populations for clinical studies, trials and advanced therapeutics

Funding:

  • Up to $50,000 to support one year of research
  • One award anticipated for this funding cycle
Children’s Health & Pediatrics

The Alpha Omega Alpha/Pharos Poetry Award

Alpha Omega Alpha Honor Medical Society
Private
United States
US $1,500

The Alpha Omega Alpha/Pharos Poetry Award

To encourage students to write effective poetry. Winning poems are published in The Pharos.

The Award

Up to 5 poems will receive a $1,500 award. The winning entries will be published in The Pharos.

Poetry Education - Higher Education

Summer Medical Internship Program (SMIP)

The Society of Interventional Radiology Foundation
Association/Society
United States
Up to US $6,000

Summer Medical Internship Program (SMIP)

Fosters an interest in research by funding a summer research project conducted by a medical student.

The SIR Foundation Summer Medical Internship Program introduces medical students to interventional radiology research and medical device development. The goal of this program is to foster an interest in research by funding a summer research project conducted by a medical student.

Students applying for the program must show strong potential for a career in IR with proven academic success. Selected students will have an opportunity to intern with an interventional radiologist research mentor or corporate research and development mentor for 8 weeks during the summer.

SIR Foundation will provide a $6,000 stipend to help ease the financial burdens throughout their internship experience.

  • Budget: Up to $6,000
  • Grant Length: Eight weeks
Apprenticeship & Internship Programs Medical Education & Professional Training

Minneapolis Grants for Nonprofits Highlights

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Grant Insights : Minneapolis Grants for Nonprofits

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

200+ Minneapolis grants for nonprofits grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

39 Minneapolis grants for nonprofits over $25K in average grant size

11 Minneapolis grants for nonprofits over $50K in average grant size

35 Minneapolis grants for nonprofits supporting general operating expenses

100+ Minneapolis grants for nonprofits supporting programs / projects

600+ Grants on Instrumentl focused on Food Access & Hunger

8,000+ Grants on Instrumentl focused on Education - Higher Education

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Minneapolis grants for Nonprofits?

Most grants are due in the first quarter.

Q1
31.1%
Q2
20.8%
Q3
26.2%
Q4
21.9%

Typical Funding Amounts

What's the typical grant amount funded for Minneapolis Grants for Nonprofits?

Grants are most commonly $12,499.

$200 $200 Min.
$12,499 $12.5 K Median
$351,654 $351.7 K Average
$37,000,000 $37 M Max.

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