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Best Large Grants for Nonprofit Organizations in Minnesota

Find the perfect Large Grants for Nonprofit Organizations in Minnesota on Instrumentl. 10,000+ Large Grants for Nonprofit Organizations in Minnesota in the United States.

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$2.71B

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$5K

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10,000+ grants
$2.71B total
$5K median

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NIH Stroke Clinical Trials Network (StrokeNet) Infrastructure – National Coordinating Center (NCC) and National Data Management Center (NDMC)

National Institutes of Health
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NIH Stroke Clinical Trials Network (StrokeNet) aims to enhance stroke treatment and recovery through a robust national infrastructure. Funded by the National Institutes of Health, this initiative focuses on clinical trials that evaluate innovative therapies for stroke patients and those at risk. The program is currently not soliciting applications but encourages the development of collaborations to support the national coordinating center and data management efforts, ultimately improving outcomes for individuals affected by stroke.
Neurological Diseases & Disorders Medical Rehabilitation Preventative Healthcare

Charles and Eleanor Rycenga Education Fund Scholarship

Grand Haven Area Community Foundation
Private
United States
Unspecified amount

Scholarships

Grand Haven Area Community Foundation scholarships are awarded competitively based on criteria set by donors. These criteria could include financial need, the school the applicant is attending, academic achievement, as well as personal or career goals. The Community Foundation has a rigorous internal selection process for each scholarship decision, and each applicant is reviewed in depth, and considered thoroughly.

Our scholarship program is simple. You are able to apply once for all foundation scholarships you may be eligible for. Once your application is submitted, you will be eligible for all those for which you meet the requirement.

Charles and Eleanor Rycenga Education Fund

Charles Rycenga and his wife Eleanor were well known in the Tri-Cities area for their philanthropy and community involvement.

In 1991, Mr. and Mrs. Rycenga established this scholarship fund to assist graduates of Grand Haven, Spring Lake, and Western Michigan Christian High Schools to continue their education.

Education - Higher Education Educational Access & Equity Vocational & Trade Education +1 more

NIDCD Mentored Career Development Award for Postdoctorate Au.D./Ph.D. Audiologists (K01 Clinical Trial Required)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $105,000
The NIDCD Mentored Career Development Award supports postdoctoral Au.D./Ph.D. audiologists in their research and career development. This grant aims to foster independence in scientific health-related research relevant to the NIDCD's mission. Key deadlines for applications span from June 2024 to May 2027, providing numerous opportunities for eligible candidates to secure funding and advance their careers in the biomedical and clinical sciences.
Hearing Disorders & Audiology Medical Education & Professional Training

Amyloidosis Fund

Healthwell Foundation
Private
United States
Up to US $8,000
The Amyloidosis Fund, managed by the HealthWell Foundation, provides essential financial assistance to underinsured patients facing treatment costs for Amyloidosis. The program covers prescription copays, insurance premiums, and related expenses, ensuring that patients can access necessary medications without financial strain. With a maximum award of $8,000, the fund aims to alleviate the burden of healthcare costs for those diagnosed with this complex disease, promoting better health outcomes and quality of life for patients across the United States.
Health Care Access & Delivery Cancer / Oncology Endocrine & Metabolic Diseases

Virginia Randolph Scholarship

The Community Foundation for a Greater Richmond
Private
United States
US $5,000
The Virginia Randolph Scholarship, established in 1963, honors the legacy of a pioneering educator in Henrico County. Managed by The Community Foundation for a Greater Richmond, this scholarship supports graduating high school seniors who demonstrate academic promise, community service, and financial need. It ensures a lasting tribute to Virginia Randolph’s commitment to education and helps empower the next generation of leaders in the region. Eligible students can receive tuition assistance for higher education pursuits.
Education - Higher Education Education - High School Academic Scholarship Programs +1 more

The Yass Prize

Yass Foundation for Education
Corporate
United States
US $1,000,000
The Yass Prize & STOP Awards Initiative aims to revolutionize education by recognizing and supporting exceptional education providers focused on Sustainable, Transformational, Outstanding, and Permissionless (STOP) education. Established in 2021, the initiative awards funds to organizations serving Pre-K to 12th grade students across the United States, fostering impactful partnerships and innovative practices. With a commitment to transforming educational experiences, the initiative celebrates the vital work of educators in response to contemporary challenges.
Educational Access & Equity Education System Policy & Reform Education - K through 12 +1 more

NewSchools: Learning Differences Grant Program

NewSchools Venture Fund
Private
United States
US $150,000 - US $250,000
The NewSchools Learning Differences Grant Program aims to enhance educational opportunities for students who learn differently, particularly those affected by poverty and racism. The program invests in innovative solutions and models that support personalized education for these students, ensuring they have access to quality instruction and belonging within school communities. With a focus on equity, it seeks ideas that align with its core investment areas and addresses the needs of marginalized learners.
Education - K through 12 Teacher Development & Training Career / College Preparation +1 more

Early Career Research Programs: POST Program Grant

Alex’s Lemonade Stand Foundation for Childhood Cancer
Private
Canada, United States
Up to US $5,000
The Early Career Research Programs: POST Program Grant aims to attract and retain promising early career scientists in pediatric oncology research. This summer internship offers students from underrepresented communities a chance to gain hands-on experience through mentorship and real-time research projects. With funding up to $5,000, it prioritizes student stipends and encourages diverse participation. Students must commit to an 8-10 week program, fostering professional growth and networking opportunities within the field.
Pediatric Cancers Diversity, Equity & Inclusion

Aryln J. Walt Memorial Scholarship

Grand Haven Area Community Foundation
Private
United States
Unspecified amount

Scholarships

Grand Haven Area Community Foundation scholarships are awarded competitively based on criteria set by donors. These criteria could include financial need, the school the applicant is attending, academic achievement, as well as personal or career goals. The Community Foundation has a rigorous internal selection process for each scholarship decision, and each applicant is reviewed in depth, and considered thoroughly.

Our scholarship program is simple. You are able to apply once for all foundation scholarships you may be eligible for. Once your application is submitted, you will be eligible for all those for which you meet the requirement.

Arlyn J. Walt Memorical Scholarship Fund

Arlyn J. Walt was a farmer who worked hard to provide, a husband who loved his wife, Kathy, and a good neighbor - always willing to help a friend. He was a third-generation dairy farmer and was known for his kindness and generosity, his love for God, and his passion for the farm. He was a member of the Farm Bureau and active in the Michigan Milk Producers Association. Kathy hopes to continue to inspire future farmers to enable their work to nourish generations with this scholarship. This scholarship is awarded to students from the Coopersville area interested in studying agriculture.

Education - Higher Education Farms & Farming Agricultural Education

Virginia Scott Memorial Scholarship

Community Foundation for Mason County, MI
Association/Society
United States
Unspecified amount

Community Foundation for Mason County, MI

At the Community Foundation for Mason County, we work with donors, grantees, and advisors to address key community issues. As a leader in community philanthropy, building a vibrant community with great opportunities for all, we are focused on advancing education, increasing recreation opportunities, and community and economic development.

The mission of the Community Foundation is to engage donors and connect them with opportunities to make a lasting impact, build community endowment, provide leadership on key issues, and make grants that reflect the communities we serve.

Virginia Scott Memorial Scholarship

This scholarship has been made possible by the generosity of the Ludington Area School District, which established the Virginia Scott Memorial Scholarship of the Community Foundation for Mason County.

This scholarship is presented to a graduating senior of Ludington High School with a cumulative grade point average of 2.8 or higher on a 4-point scale. The recipient must pursue a degree or certification at any two or four-year accredited college, university, or vocational/technical school.

Education - Higher Education Academic Scholarship Programs College Success / Persistence +1 more

Spencer Educational Foundation: Course Development Grants

Spencer Educational Foundation Inc
Private
Canada, United States
US $10,000 - US $25,000

Spencer Educational Foundation Inc

The Spencer Educational Foundation was founded by the Rims Atlanta Chapter in 1979. To this day, Spencer remains the premier organization funding the education of tomorrow's risk management and insurance leaders.

The Spencer Educational Foundation: awards merit-based scholarships and grants to university students pursuing careers in risk management, insurance, and/or actuarial science; provides grants that create experiential learning opportunities both on and off campus; funds the development of risk management and insurance curricula in colleges and universities; supports Risk Managers by creating internship opportunities within the risk management function of their companies; and operates across the United States and Canada. 

Spencer Educational Foundation: Course Development Grants

Since 2014, Spencer has invested over $1.6 million in developing risk management and insurance (RMI) courses at close to 70 colleges and universities, exposing approximately 19,000 students to the RMI industry.

Our Course Development Grant program supports Introductory Risk Management and Insurance Course Development - for universities that have not previously offered any such instruction - as well as proposals for additional Course Curriculum Development and Program Development - for universities looking to develop a RMI program and/or expand existing RMI course offerings, with an emphasis on new and emerging areas in the industry.

Workforce Preparation & Job Readiness Academic Success & Enrichment Curriculum Development

Health and Extreme Weather Solutions-Focused Research Hubs (U54 - Clinical Trial Optional)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $2,000,000
The National Institute of Environmental Health Sciences (NIEHS) is launching a funding opportunity for research hubs focused on the health impacts of extreme weather. This initiative encourages multidisciplinary teams to engage with community partners on issues such as wildfire smoke and extreme heat. Emphasizing collaboration, the program aims to develop scalable solutions and measurable public health outcomes, leveraging resources and expertise across institutions to address climate-related health challenges effectively.
Health & Medicine Atmospheric Sciences Climatology +2 more

Hertz Foundation Travel Fund

Fannie and John Hertz Foundation
Private
Countries
US $2,000 - US $5,000

About the Hertz Foundation

Empowering the Nation’s Most EXCEPTIONAL Innovators

The Hertz Foundation identifies and empowers the nation’s most exceptional innovators in science and technology, fueling a lifelong community dedicated to solving our most pressing problems.

Hertz Community

Awards & Recognition

We’ve established several awards to recognize and support Hertz community members who are accelerating solutions to significant real-world challenges, either through their individual careers or volunteering to strengthen the Hertz Foundation’s work. In addition to providing financial and professional support at a critical time, we also hope to generate more awareness within the Hertz community and inspire collaborations that build on the momentum.

Hertz Foundation Travel Fund

The Hertz Foundation Travel Fund provides financial support to Hertz Fellows to advance their professional growth through conference travel and interdisciplinary engagement. Awardees receive a lump sum of $2,000 for domestic or $5,000 for international travel.

Supporting professional development

Established in 2025, this funding provides Fellows with critical support to enhance their career and professional development. Funding is designated to support travel to attend technical conferences, interdisciplinary or entrepreneurial convenings and workshops or seminars that catalyze new career paths, research directions or cross-sector collaborations.

Engineering Mathematics Science +1 more

Transport Phenomena (TP)

National Science Foundation (NSF)
Federal Government
United States
Unspecified amount
The Transport Phenomena (TP) program, supported by the National Science Foundation, aims to advance fundamental research in the transport of mass, momentum, energy, and species across various scales. This initiative focuses on innovative methodologies that enhance our understanding of single- and multiphase systems, thermodynamic processes, and combustion dynamics. By integrating theoretical, experimental, and computational approaches, TP seeks to connect microscale phenomena with broader engineering applications, ultimately contributing to national priorities in energy, biotechnology, and environmental sustainability.
Engineering Bioengineering Chemical Engineering +5 more

Clarence W. Seavers Citizenship Scholarship

Erie County Community Foundation
Private
United States
Unspecified amount
The Clarence W. Seavers Citizenship Scholarship supports graduates from Erie County, Ohio high schools pursuing degrees in Political Science or Computer Science/Technology. With a minimum GPA requirement of 3.0, this scholarship can be renewed for up to three additional years at the discretion of the Scholarship Advisory Committee, without considering financial need. It emphasizes leadership, spirituality, and community service, aiming to empower students to contribute positively to their communities.
Education - Higher Education Education - High School Academic Scholarship Programs +2 more

UCAR Next Generation Fellowship

University Corporation for Atmospheric Research
Private
Canada, Mexico +1 more
US $40,000
The UCAR Next Generation Fellowship offers graduate students a unique opportunity to engage in Earth System Science research while addressing societal impacts. With a $40,000 fellowship over two years, participants can expect mentorship from UCAR leaders and professional development training. This program encourages interdisciplinary exploration, allowing fellows to collaborate closely with experts, attend conferences, and build lasting networks. It aims to empower diverse students as future change-makers in the field, fostering a commitment to equity and innovation.
Earth Science Public Policy Atmospheric Sciences +6 more

Small Business Transition Grant for New Entrepreneurs (R41/R42 Clinical Trial Required)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
United States
Up to US $2,352,688
The Small Business Transition Grant for New Entrepreneurs, offered by the NIH, supports the career development of new investigators transitioning into entrepreneurship. It focuses on training and mentoring Program Directors/Principal Investigators in small business environments, enhancing their research and entrepreneurial skills. This grant is aimed at scientists with strong backgrounds in research and technology but limited experience in leading independent projects. The initiative ultimately seeks to foster innovative technologies that align with NIH's health improvement mission.
Entrepreneurship Medical Education & Professional Training Emerging Technology Development +2 more

W. J. Blanchet Scholarship

The Community Foundation for a Greater Richmond
Private
United States
US $2,000
The W. J. Blanchet Scholarship, offered by The Community Foundation for a Greater Richmond, supports graduating high school seniors from Northumberland County who demonstrate financial need and a commitment to academic excellence and community service. Preference is given to members of local churches. This scholarship aims to empower students to pursue higher education at accredited institutions, fostering educational growth and community engagement in the region.
Education - Higher Education Education - High School Academic Scholarship Programs +2 more

Virginia Urology Center Scholarship

The Community Foundation for a Greater Richmond
Private
United States
US $2,000

The Community Foundation for a Greater Richmond

The Community Foundation of Richmond is a philanthropic organization dedicated to improving quality of life across the Richmond region by connecting people, ideas, and resources for lasting community impact. The Foundation manages charitable funds, supports local nonprofits, and leads strategic initiatives that address community priorities such as education, health, economic opportunity, and equity. Through grantmaking, donor services, and community leadership, the Foundation works to strengthen nonprofits, respond to emerging needs, and build a more resilient, inclusive, and thriving Richmond-area community.

Virginia Urology Center Scholarship

The Virginia Urology Center Scholarship Program was established in 1999 to benefit graduating seniors from public and private high schools in communities where Virginia Urology offices are located, including Metropolitan Richmond, the Tri-Cities, Northern Neck, Middle Peninsula and South Hill. The scholarship supports post-secondary study in the fields of science and medicine. Funds awarded will help to cover the costs of tuition, room, board, books and laboratory fees.

Education - Higher Education Education - High School Academic Scholarship Programs +2 more

Fiscal Year (FY) 2027 Department of War (DoW) Multidisciplinary Research Program of the University Research Initiative (MURI) (363905)

US DOD: U.S. Army Materiel Command
Federal Government
American Samoa, Guam +4 more
Up to US $7,500,000
The FY 2027 Department of War Multidisciplinary Research Program (MURI) funds U.S. academic teams engaged in innovative basic research addressing future defense challenges. Established in 1985, MURI emphasizes collaboration across multiple scientific disciplines to tackle complex, DoW-relevant issues. By fostering partnerships among faculty, postdoctoral researchers, and students, the program aims to advance the U.S. defense industrial base and nurture a skilled scientific workforce, contributing to significant breakthroughs in military technology and economic growth.
Engineering Science Workforce Preparation & Job Readiness +1 more

Rural Communities Opioid Response Program - Community Systems Development

Health Resources and Services Administration
Federal Government
American Samoa, Guam +7 more
Up to US $500,000
The Rural Communities Opioid Response Program (RCORP) - Community Systems Development aims to enhance behavioral health systems in rural areas by providing funding for the development and expansion of services. This initiative supports the establishment of formalized networks to boost operational and clinical capacity, ensuring effective implementation of evidence-based substance use disorder prevention, treatment, and recovery services tailored to community needs.
Rural Development Rural Health Care Community Services +1 more

Richard J. & Irma E. Larson Scholarship Endowment Fund

Community Foundation of the Fox River Valley
Private
United States
US $1,000

Community Foundation of the Fox River Valley

The Community Foundation of the Fox River Valley is a collection of individual funds and resources given by local citizens to enhance and support the quality of life in the Fox River Valley of Illinois.

We are a tax-exempt public charity that allows individuals, businesses, and non-profit organizations to establish permanent endowments and temporary funds within the confines of one large foundation.

Foundation funds are used to provide grants to non-profit organizations and scholarships to area students. The Foundation also hosts a Youth Engagement in Philanthropy (YEP) program, which helps high school students learn more about philanthropy and empowers them to make a difference in the community.

The Community Foundation of the Fox River Valley serves the City of Aurora, Kane County, and Kendall County within the State of Illinois.

Richard J. & Irma E. Larson Scholarship Endowment Fund

The Richard J. and Irma E. Larson Scholarship Endowment Fund was established to help Aurora area high school graduates attend colleges and universities to further their education in the fields of law, teaching, Christian ministry and agriculture.

Richard, better known as Dick, and Irma are both graduates of Wartburg College in Waverly, Iowa. Dick received his Juris Doctor Degree from the University of Illinois College of Law. Irma earned her Master’s Degree from Northern Illinois University.

Irma has served on several community boards, including Child Welfare, the Aurora YWCA, P.E.O. Chapter DD, and The Mid-West Early American Pressed Glass Club. After retirement, she volunteered as a Court Appointed Special Advocate (CASA) for nine years.

The monetary value of each scholarship award varies depending upon the amount available in each individual scholarship fund. The most common scholarship award amount is $1,000 for a single year. Scholarships are designated as non-renewable one-year awards or renewable multi-year awards depending upon the scholarship fund criteria, as established by the donor of the scholarship fund.

Law Education Education - Higher Education +2 more

Palumbo Charitable Trust Grants

A.J. and Sigismunda Palumbo Charitable Trust
Private
United States
Unspecified amount
The A.J. and Sigismunda Palumbo Charitable Trust supports organizations committed to enhancing the lives of children and young adults. They focus on educational institutions, health-related initiatives, and community services in the St. Marys, Pennsylvania area. Grants are awarded to 501(c)(3) organizations demonstrating accountability and measurable outcomes, with a preference for projects that benefit the community at large. The Trust encourages collaborative funding efforts and endeavors that inspire hope and vision.
Youth Services Community Services Catholicism +2 more

Sony: Corporate Giving

Sony Corporation of America
Corporate
United States
Unspecified amount
Sony Corporation of America focuses its charitable giving on arts, culture, technology, and the environment, with a strong emphasis on education in these fields. It supports registered 501(c)(3) non-profit organizations while ensuring that their contributions encourage the development of the creative and technical skills essential for future workforce needs. Notably, multi-year requests and various exclusions, including those based on discrimination, are not considered.
Environmental Education Computer Science & Engineering Emerging Technology Development +2 more

Native American Library Services Basic Grant (2027)

Institute of Museum and Library Services (IMLS)
Federal Government
United States
US $6,000 - US $10,000
The Native American Library Services Basic Grant (NAB) aims to enhance library services for Native Communities. By supporting the acquisition of materials, programming, and staff training, the program empowers Tribal libraries to adapt to evolving information needs. This initiative fosters knowledge centers that contribute to community wellness and cultural preservation. Through targeted project activities, the NAB program ensures that libraries effectively meet their users' diverse needs, promoting accessibility and engagement across the nation.
Community Services Library & Information Science Native American Services +1 more

Staab Construction Scholarship

Marshfield Area Community Foundation Inc.
Private
United States
Unspecified amount

About Us

Marshfield Area Community Foundation, Inc. is a public, 501-C-3 charity. There are 30 community foundations in Wisconsin and more than 750 in the nation. The purpose of all community foundations is to accumulate charitable dollars that impact a specific geographic region in areas such as education, the arts, economic development, recreation, environmental protection, health care, and social services. They may be relatively small, as we are (assets of $14 million), or very large, as is the Greater Milwaukee Foundation (assets over $400 million).

Most people are familiar with private foundations, established by individuals, families, or corporations. Typically, in order to establish a private foundation, one has to have considerable wealth. You could say Community Foundations are much more democratic. We are, in a sense, an umbrella foundation containing many small foundations. We call those small foundations “funds.”

Marshfield Area Community Foundation Scholarships

The mission of the Marshfield Area Community Foundation is “Connecting people who care with causes that matter to enrich the quality of life in the Marshfield area”. Education is a valuable tool and a cause that matters to all of us. Through assisting students with financial support to receive an education, not only do students and the families of those students benefit, but also our community benefits, which further allows us to achieve our mission of enriching the quality of life in the Marshfield area.

Staab Construction Scholarship (2025)

Education - Higher Education Educational Access & Equity Engineering +2 more

John Jamison Iron Mountain Education Fund Grant

Iron Mountain Foundation
Private
Asia, Australia +10 more
US $2,000
The John Jamison Iron Mountain Education Fund provides scholarships to encourage educational pursuits among the children of Iron Mountain employees. Established in 2004, it awards $2,000 to selected applicants and $4,000 to those majoring in STEM fields. Eligibility includes dependent children of full-time employees at the Director level and below, along with deceased employees' children. The number of scholarships varies annually based on available funds, supporting students in their quest for higher education.
Academic Scholarship Programs Mathematics STEM / STEAM Education +4 more

Large Grants for Nonprofit Organizations in Minnesota Highlights

Looking for large grants for nonprofit organizations in Minnesota?


Read more about each grant below or start your 14-day free trial to see all large grants for nonprofit organizations in Minnesota recommended for your specific programs.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Large Grants for Nonprofit Organizations in Minnesota

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

300+ Large Grants for Nonprofit Organizations in Minnesota grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

100+ Large Grants for Nonprofit Organizations in Minnesota over $25K in average grant size

100+ Large Grants for Nonprofit Organizations in Minnesota over $50K in average grant size

49 Large Grants for Nonprofit Organizations in Minnesota supporting general operating expenses

200+ Large Grants for Nonprofit Organizations in Minnesota supporting programs / projects

1,000+ Grants on Instrumentl focused on Workforce Preparation & Job Readiness

600+ Grants on Instrumentl focused on Food Access & Hunger

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Large grants for Nonprofit Organizations in Minnesota?

Most grants are due in the fourth quarter.

Q1
27.8%
Q2
24.1%
Q3
19.9%
Q4
28.3%

Typical Funding Amounts

What's the typical grant amount funded for Large Grants for Nonprofit Organizations in Minnesota?

Grants are most commonly $49,999.

$300 $300 Min.
$49,999 $50 K Median
$524,264 $524.3 K Average
$40,331,313 $40.3 M Max.

Average Grant Size

What's the typical amount funded for Minnesota?

Grants are most commonly $118,274.

$118,274

Total Number of Grants

What's the total number of grants in Large Grants for Nonprofit Organizations in Minnesota year over year?

In 2024, funders in Minnesota awarded a total of 56,278 grants.

2022 54,862

2023 52,544

2024 56,278

Top Grant Focus Areas

Among all the Large Grants for Nonprofit Organizations in Minnesota given out in Minnesota, the most popular focus areas that receive funding are Education, Human Services, and Philanthropy, Voluntarism & Grantmaking Foundations.

1. Education

2. Human Services

3. Philanthropy, Voluntarism & Grantmaking Foundations

Funding Over Time

How is funding for Large Grants for Nonprofit Organizations in Minnesota changing over time?

Funding has increased by -10.55%.

2022 $6,166,461,795

2023 $7,425,303,965
20.41%

2024 $6,642,167,971
-10.55%

Minnesota Counties That Receive the Most Funding

How does grant funding vary by county?

Hennepin County, Olmsted County, and Ramsey County receive the most funding.

County Total Grant Funding in 2024
Hennepin County $2,523,121,165
Olmsted County $1,922,001,946
Ramsey County $1,159,108,356
Washington County $321,318,471
Blue Earth County $287,516,198