Best Large Grants for Nonprofit Organizations in Minnesota

The NIH Pathway to Independence Award (K99/R00) aims to enhance the career development of promising postdoctoral researchers by transitioning them into independent faculty positions. This program supports innovative research during the critical transition phase, enabling awardees to establish successful, independent research careers. Key application deadlines span from June 2024 to February 2027, with specific dates for standard, renewal, and AIDS-related applications. This initiative is vital for fostering a new generation of NIH-supported investigators.

Basin Electric Power Cooperative's Charitable Giving Program focuses on supporting communities across its nine-state service territory. The program reviews funding requests periodically and allocates donations to various categories, including education, health services, civic betterment, and cultural initiatives. Additionally, it offers matching funds for member donations and contributes surplus office equipment to organizations in need. This commitment to community growth and sustainability reflects Basin Electric's mission to enhance the well-being of its members.

The NIH Pathway to Independence Award (K99/R00) supports the transition of postdoctoral researchers to independent faculty positions. It aims to enhance the number of talented NIH-supported investigators by providing funding during their transition to independent research careers. Key deadlines for applications are set for various dates through 2027. This program is crucial for developing a strong cohort of new independent researchers, fostering innovation in health-related fields.

The ISF Public Interest Legal Fellowship empowers American Muslims by providing opportunities in public interest law. This fellowship offers a salary of $70,000, professional development workshops, and mentorship to help fellows advance their careers. Applicants must be active members of the Muslim community, have graduated from law school within the last three years, and have secured a host organization for their project proposal. This initiative aims to increase representation and influence in policy-making.

Self-Defense Grants for MMIR Day

Facilitators, educators, organizers — May 5th is the Day of Awareness for Missing & Murdered Indigenous Women, Girls and Relatives. In honor of that day, we are offering mini grants to host a self-defense workshop for Indigenous girls and gender-expansive youth.

Why self-defense?

• Native women are murdered at 10x the national rate
• 84% experience violence in their lifetime
• Over 5,700 Native girls go missing each year

We also name the invisible crisis:

• Indigenous people from Mexico & Central America (Maya, Nahua, Zapotec, Mixtec, Lenca, and others) living in the U.S. face detention, deportation, and disappearances that are rarely counted in MMIR data.
• When a Tzotzil 18 year old like Royer Perez Jimenez dies in ICE custody, the silence is deafening.

Self-defense must include all Indigenous relatives.

XCNC has:

• $500 mini grants for stipends, space, supplies, and translation.

What we ask:

• Plan a workshop between May 5–31, 2026, rooted in community care.

Innovation in Religion and Spirituality Seed Grants Call for Proposals

The Religion and the Public Sphere program at the Social Science Research Council aims to foster research on the wider implications of new forms of religious and spiritual life. This program is offered with the support of the Luce Foundation, the John Templeton Foundation, and the Templeton World Charity Foundation.

Overview

In recent years, scholars have noted that religious and spiritual life is being substantively reshaped. “Innovation” is one way of framing these changes, but it remains a partial and contested analytic lens, and is popularly associated with the sudden emergence of a “new” element introduced into an otherwise static tradition. Scholarship on religion and spirituality, however, points to a more complex set of processes. The essays in an ongoing forum for The Immanent Frame have set out some initial parameters of these dynamics: rather than invention ex nihilio, what we often see is the strategic recombination of existing elements within a broader context of social, political, and cultural change.

Research Themes

This request invites proposals that examine the dynamics of religious and spiritual change that fall within the frame of “innovation.” Possible topics include, but are not limited to: 

• Explorations of innovations within transnational or diasporic religious and/or spiritual communities within the United States, particularly related to the circulation of ideas and culture from or to the Global South.   
• Gendered knowledge of innovation. 
• Studies of the process by which an innovation attains—or does not attain—legitimacy, relevance, or authority within a given community or institution. 
• The relationship between contemporary economic conditions—poverty, economic insecurity, and competitive pressures for time and money—and innovations in religion and spirituality. 
• Historical studies of innovations in religion and spirituality; the creation, reception, transformation, and longevity of an innovation over time.  
• Civic participation and the social mobilization of new or innovative religious identities, as well as the reinterpretation of religious or spiritual traditions or ideas in the service of particular political or ideological projects.

Program Terms 

The program offers research support over a period of up to 6 months. The grant funds will be up to $10,000 per award.

National Main Street Center Inc.

Main Street America (MSA) leads an inclusive, impact-driven movement dedicated to reenergizing and strengthening older and historic downtowns and neighborhood commercial districts through place-based economic development and community preservation. We work in collaboration with thousands of local partners and grassroots leaders across the nation who share our commitment to advancing shared prosperity, creating resilient economies, and improving quality of life.

Main Street America was founded in 1980 as the National Main Street Center®, a program of the National Trust for Historic Preservation. Over the past 40 years the MSA network has helped to generate over $115.27 billion in local reinvestment, rehab 345,801 buildings, create 815,894 new jobs, and start 181,647 new businesses in over 2,000 communities. 

Great American Main Street Awards

Main Street America celebrates communities whose successes serve as a model for comprehensive, preservation-based revitalization efforts in their historic downtowns and commercial corridor districts with the Great American Main Street Awards (GAMSA).

Winners represent the diversity of communities in the Main Street America network — small towns, mid-sized communities, and urban commercial districts from every region in the country — and demonstrate the power of the Main Street Approach™. Since the inception of the Great American Main Street Awards in 1995, 118 Main Street programs have been honored.

Selection Criteria: Semifinalists and winners are selected from a nationwide pool of applicants by a jury of Main Street professionals and leaders in the fields of community and economic development and historic preservation. Criteria for winning GAMSA include: strength of the Main Street program in spurring community transformation, commitment to historic preservation, innovative programming, implementation of cross-sector partnerships, community outreach and stakeholder engagement, and ensuring their downtown districts are for everyone. 

Accolades & Ceremony: Semifinalists are promoted through Main Street America’s digital channels and receive media relations support. Winners also receive a short documentary film, a plaque, communications and media relations support, prominent placement on the Main Street America website for two years, and recognition at the 2027 Main Street Now Conference in Detroit, Michigan.

The I9 Sports Association provides scholarship grants to support youth sports participation for children under 18 in the U.S. Grants of up to $150 help offset registration fees for various recreational activities. With a focus on inclusivity and access, the association aims to foster athletic development and participation among young athletes. Applications are accepted year-round, with grants awarded in February, May, August, and November, ensuring ongoing support for youth sports engagement.

The J.M. Heberlig/B.J. Helterbran Scholarship Fund, established by dedicated educators, supports Pennsylvania residents pursuing degrees in Art Education or Recreation & Parks. This scholarship aims to alleviate the financial burden on students entering their second, third, or fourth year at a 4-year institution. With a focus on academic achievement, a minimum GPA of 2.8 overall and 3.0 in the major is required, alongside a demonstrated commitment to education and community service.

The Paul Purcell "Kids Win!" Annual Baird Education Grant honors the legacy of former Baird CEO Paul E. Purcell, who dedicated his life to educational causes. Established in 2020, this grant supports 501(c)(3) organizations that ensure all children, regardless of circumstances, have access to quality education. Funded by Baird and its associates, it prioritizes programs serving diverse and underserved populations, embodying Purcell's belief that every child deserves the opportunity to succeed.

Communities Foundation of Oklahoma

The Communities Foundation of Oklahoma stems from the vision of Tom McCasland Jr., and Gene Rainbolt. Two decades ago, these gentlemen formed a shared vision to create a single philanthropic organization to serve the charitable needs to rural communities across the great state of Oklahoma. Today, CFO has grown to assist hundreds of efforts in more than 45 counties.

Scholarship Opportunities

CFO offers over 100 diverse scholarship opportunities, empowering students across the state to pursue their educational goals. Each scholarship is tailored to meet unique needs, making higher education more accessible for all.

Ashley Parks Creative Scholarship

Supports continued education in the arts or creative fields for non-traditional students.

The Tommy Wilson Memorial Grant, established by Dr. George T. Wilson and his wife Irene, honors their son Tommy, who had cerebral palsy. This grant supports recreational programs for individuals with disabilities and aims to positively impact their lives. Applicants must be nonprofit organizations with a successful history of programming for individuals with disabilities. The grant prioritizes programs serving economically disadvantaged individuals and may only fund applicants once every five years.

The Delano Area Community Foundation Grant aims to strengthen communities through local philanthropy. Established in 2014, it focuses on creating a sustainable funding source for community needs. The foundation invites 501(c)(3) nonprofits, government units, and public schools in the Delano area to apply for grants that enhance education, promote development, and enrich cultural activities. With over $10,000 awarded since its inception, it fosters community engagement and supports impactful projects.

The Pillager Education Foundation Grant supports student excellence in academics, arts, athletics, and community activities through innovative funding. As a Partner Fund of the Initiative Foundation, it manages contributions to enhance educational opportunities and community engagement. Interested applicants should contact the fund's advisory team for guidance on the application process. This grant aims to empower students and enrich their learning experiences, ensuring sustainable support for future generations.

Linda Norton Good Neighbor Scholarship

This scholarship is designed to support exceptional students within the Poudre School District who aspire to pursue degrees in finance, economics, business, or real estate. It embodies Linda Norton’s legacy of community service, advocacy, and significant contributions to the field while providing opportunities for the next generation of students in these related disciplines.

Scholarship amount:

• $1,500

Number of awards:

• 1

Scholarship awards are one-time awards. The amount awarded to a selected recipient may be used for the cost of attendance. All scholarships will be paid directly to the recipient’s school and must be used for the upcoming academic year. Award disbursement is contingent upon the outside scholarship policies of a recipient’s college or university.

Community Foundation of the Holland/Zeeland Area

Our Mission

The Community Foundation of the Holland/Zeeland Area seeks to ensure that our community thrives today, tomorrow, and forever by building our Community’s Endowment to support high impact charitable projects, helping donors achieve their charitable goals, and leading and partnering in community-level initiatives.

Scholarships

CFHZ awards over $1 million in scholarships each year for students to attend schools of higher education throughout the nation. Our scholarships are possible thanks to the generosity of donors who invest in our community’s future by furthering the education of others.

All Holland/Zeeland area individuals interested in post-secondary education are encouraged to apply for CFHZ scholarships.

The Foundation proudly administers over 100 scholarships, each with unique eligibility criteria that must be met before a candidate can be considered.

Peter and Huberdina Weller Scholarship

• Graduating senior, graduating early college student, or current college student from a high school within the greater Community Foundation service area
• Enrolling/enrolled at an accredited post-secondary school within the United States
• Financial need (must submit the page of the FAFSA Submission Summary showing the Student Aid Index amount)
• GPA of 3.0 or greater
• Intention to pursue educational opportunities and a career in horticulture or the biological sciences with an emphasis on botany
• All other qualifications being equal, tie-breaking consideration will be given to students of color
• Previous recipients of the award are encouraged to reapply.

The Hackensack Lakes Area Community Foundation, under the Initiative Foundation, provides grants to empower Central Minnesota communities. It focuses on projects that promote community development, environmental sustainability, and health. Eligible applicants include 501(c)(3) nonprofits and government units serving the Hackensack area. The foundation encourages collaboration with local organizations for innovative ideas, ensuring a lasting culture of generosity. Applications are accepted continuously, with quarterly awards based on a competitive review.

The Wolcott Family Foundation focuses on funding grassroots organizations that drive social change and environmental stewardship. They prioritize support for projects that empower communities, strengthen civil liberties, and address ecological challenges. Eligible applicants are nonprofit organizations in Colorado classified under section 501(c)(3), with grants awarded for one year. The foundation values projects emphasizing environmental preservation and community involvement aimed at tackling societal issues.

The Safety, Security, and Privacy for Open-Source Ecosystems (Safe-OSE) program, launched by the National Science Foundation (NSF), addresses vulnerabilities in open-source products and their development infrastructure. It invites proposals to enhance safety, security, and privacy across various types of open-source ecosystems. The program aims to support initiatives that improve resilience against risks, attacks, and breaches, ensuring that OSEs can effectively manage current and future challenges.

The DEVCOM Analysis Center Broad Agency Announcement invites research proposals to support the U.S. Army's mission of informed modernization through data-driven analysis and technology development. Open until January 4, 2028, it seeks innovative whitepapers and proposals from various organizations to enhance Army capabilities and technologies. This initiative aims to foster significant advancements that align with national security needs and drive scientific exploration in applied research and advanced technology.

The John K. Fairbank Prize in East Asian History, awarded by the American Historical Association, recognizes exceptional scholarly work in the history of East Asia, particularly focusing on books published after 1800. Eligible works must demonstrate high literary merit and can be nominated by authors or publishers. The prize aims to highlight significant contributions to the historical disciplines, with recipients announced in October 2025 and honored at the January 2026 AHA annual meeting in Chicago.

The Burroughs Wellcome Fund's Career Awards at the Scientific Interface provide $560,000 over five years to support early-career researchers transitioning from physical and computational sciences to biological sciences. Launched in 1999, these awards aim to enhance academic research careers for U.S. and Canadian citizens, permanent residents, and temporary residents, fostering a diverse and innovative scientific workforce essential for advancing human health.

The Delta Project Learning Garden Grant Program, supported by the Captain Planet Foundation, enhances STEAM education through outdoor learning experiences in school gardens. It offers resources such as raised garden beds, a mobile cooking cart, and online lessons to foster student engagement with nature and healthy eating. This initiative not only enriches the educational landscape but also promotes community involvement, as Delta employees volunteer for garden installation and maintenance, ensuring a sustainable and impactful learning environment.

The Brice and Teresa Moczygemba Engineering Scholarship Fund, established by the San Antonio Area Foundation, supports students pursuing a Bachelor's degree in Civil Engineering from accredited programs in the U.S. Eligible applicants include current high school seniors and college students residing in Bexar, Karnes, or Wilson counties, with a minimum GPA of 3.6. This renewable scholarship covers tuition, fees, books, and educational expenses, reinforcing the Foundation's commitment to enhancing community well-being.

The Collins Medical Trust Grant, established in 1956, supports health-related research and professional education for tax-exempt organizations. Eligible applicants include institutions with approved tax status and a commitment to equal opportunity. Early career investigators are encouraged to apply, but funds cannot be used for individual benefits or political activities. The Trust prioritizes projects in Oregon and does not support product development for industry. Applications are accepted thrice yearly, with specific deadlines for timely consideration.

Mission: A non-profit, charitable, Private Foundation established in 1959 by the Long family to support local charities, schools, education events and general community needs.

Grants

Our approach to grant requests focuses on fostering local neighborhood vitality and excellence. The John F. Long Foundation supports local non-profit organizations that promote this objective. The Foundation looks for groups who are working to help themselves, help their own communities, and help others like themselves through self-empowering, community organizing efforts. To be eligible for consideration, the grant request must meet the following criteria:

• Funds’ use must have measurable benefits
• Your organization must have good management, a solid financial background, well-established administration policies and Board of Directors
• The grant request must be precise and complete, providing necessary detail
• The Foundation Questionnaire is to be completed in its entirety
• The grant request amount and time frame must be clearly communicated, i.e. one-time grant, ongoing support, or special project
• If your request is for a particular event or program, providing a budget is always helpful
• Requests for grants of $1,000.00 or more, as well as groups we have not funded within the past two years, must: (i) Provide financial reports/statements for past and current fiscal year; (ii) Provide a list of past donors going back no more than two years.

The Medica Foundation Grant focuses on enhancing rural health in Minnesota by funding community-led initiatives that address health equity. With grants ranging from $5,000 to $10,000, it supports projects that improve healthcare access and quality, particularly in underserved areas. Eligible applicants include 501(c)(3) organizations, government agencies, and Tribal Nations, while emphasizing measurable outcomes and culturally-focused care.