Best Large Grants for Nonprofit Organizations in Minnesota

The Burroughs Wellcome Fund's Career Awards at the Scientific Interface provide $560,000 over five years to support early-career researchers transitioning from physical and computational sciences to biological sciences. Launched in 1999, these awards aim to enhance academic research careers for U.S. and Canadian citizens, permanent residents, and temporary residents, fostering a diverse and innovative scientific workforce essential for advancing human health.

The National Cancer Institute (NCI) invites applications for transformative research in cancer biology and oncology through nanotechnology. This funding opportunity aims to address significant challenges by exploring the interactions of nanomaterials with biological systems. Projects should focus on utilizing nanoparticles and devices for targeted cancer therapies and enhancing diagnostic capabilities. Successful proposals will contribute to the foundational knowledge necessary for future nanotechnology-based interventions in cancer treatment.

The Maximizing Investigators' Research Award (MIRA) program, established by NIGMS, aims to enhance research funding efficiency by providing stable financial support to investigators. This allows for greater scientific flexibility and encourages innovative studies. MIRA is pivotal for distributing funding among promising researchers, fostering groundbreaking research. The program invites applications from eligible NIGMS-funded and NIH-defined New Investigators, as well as current MIRA grantees seeking renewal, ensuring a broad and inclusive approach to advancing science.

The Paul Purcell "Kids Win!" Annual Baird Education Grant honors the legacy of former Baird CEO Paul E. Purcell, who dedicated his life to educational causes. Established in 2020, this grant supports 501(c)(3) organizations that ensure all children, regardless of circumstances, have access to quality education. Funded by Baird and its associates, it prioritizes programs serving diverse and underserved populations, embodying Purcell's belief that every child deserves the opportunity to succeed.

The Louisville Institute offers the Grant for Researchers to support academic research in North American Christianity and related fields. Grants of up to $55,000 are available for sabbatical leaves, research projects, and necessary resources. This flexible program combines previous grants to meet contemporary academic needs. Applicants can apply individually or as teams of up to three, provided they are based in the U.S. or Canada. Projects bridging scholarship and church life are of particular interest.

Excellence in Medicine Awards

The AMA Foundation’s Excellence in Medicine Awards honor physicians and medical advocates who exemplify the highest values of the profession—volunteerism, community engagement, leadership, and service to underserved populations. Each recipient is recognized at a ceremony during the AMA Annual Meeting in Chicago and receives a $2,500 grant honorarium directed to a nonprofit health organization of their choice. Since 2005, more than 100 honorees have been celebrated through this program, with over $250,000 awarded to strengthen community health and advance equitable care nationwide. 

Excellence in Medicine Awards- Dr. Edmond and Rima Cabbabe Dedication to the Profession Award

Honors physicians who are committed to expanding knowledge through teaching, conducting research and publishing. Other qualifying virtues include leadership, volunteerism and philanthropic activities in medical and other civic organizations.

Made possible by Edmond Cabbabe, MD, and Rima Cabbabe

Excellence in Medicine Awards

The AMA Foundation’s Excellence in Medicine Awards honor physicians and medical advocates who exemplify the highest values of the profession—volunteerism, community engagement, leadership, and service to underserved populations. Each recipient is recognized at a ceremony during the AMA Annual Meeting in Chicago and receives a $2,500 grant honorarium directed to a nonprofit health organization of their choice. Since 2005, more than 100 honorees have been celebrated through this program, with over $250,000 awarded to strengthen community health and advance equitable care nationwide. 

Excellence in Medicine Awards- Dr. Debasish Mridha Spirit of Medicine Award

Recognizes the work of U.S. physicians who demonstrate altruism, compassion, integrity, leadership and personal sacrifice while providing quality health care to destitute, distressed or marginalized populations in impoverished communities.

Made possible by Debasish Mridha, MD

The Outstanding Earth Science Teacher (OEST) Award recognizes exceptional K-12 educators for their contributions to Earth Science education. Established in 1971 by the National Association of Geoscience Teachers, the award aims to stimulate interest in Earth Sciences among students. Eight national finalists are chosen annually, ensuring broad recognition and encouraging teaching excellence. Nominees can apply themselves or be nominated by colleagues, allowing for two awards in an educator's career to honor both early and late career achievements.

Our Mission

KidsGardening creates opportunities for kids to play, learn, and grow through gardening, engaging their natural curiosity and wonder.

We want every child to experience the unique transformation that occurs when they spend time caring for a garden, be it outside, in a classroom, or in a cup on the kitchen windowsill. Since 1982, KidsGardening has served as a premier support provider for youth garden programs nationwide.

We support educators and families with grant funding, original educational resources, inspiration, and community to get more kids learning through the garden.

Growing the Future Intergenerational Garden Grant

In celebration of Miracle-Gro’s 75th anniversary, Miracle-Gro and KidsGardening are partnering to fund 75 intergenerational youth garden grants in 2026.

Intergenerational gardens provide opportunities for older gardeners to pass along traditions, knowledge, and skills to the next generation or share the experience of developing skills if new to gardening. In turn, young people bring their curiosity, wonder, and contagious enthusiasm for learning and life, exciting everyone involved in the growing process.

The 2026 Growing the Future Intergenerational Garden Grant is designed to support gardens that intentionally bring children and older adults together through shared gardening experiences.

Funding Priorities

The selection of winners is prioritized based on demonstrated need and program impact. KidsGardening considers a variety of factors when determining needs, including:

• Socioeconomic & Sociodemographic Factors: How does the program exist within or engage a community that has been systematically denied resources, whether physical assets and money or representative leadership and community services? Organizations affected by multiple socioeconomic and sociodemographic factors are given priority.

• Program Funding and Support: Does an organization have access to consistent, substantial monetary support or prior grant funding? Or are pre-existing resources (financial or otherwise) limited? Organizations experiencing the latter are given priority.

• Impact: Will grant funding dramatically expand learning opportunities for program participants? Does the intended impact reflect the needs of the community? Organizations working with more than 50 youth will be given priority.

Award Packages

Grantees will receive:

• A $500 cash award check
• A $250 coupon to purchase essential gardening supplies from ScottsMiracleGro.com

About Us

The Wenner-Gren Foundation is a private operating foundation dedicated to providing leadership in support of anthropology and anthropologists worldwide.

Our Mission

The Wenner-Gren Foundation is committed to playing a leadership role in anthropology. We help anthropologists advance anthropological knowledge, build sustainable careers, and amplify the impact of anthropology within the wider world. We dedicate ourselves to broadening the conversation in anthropology to reflect the full diversity of the field.

Engaged Research Grant

General

This program supports longstanding research partnerships that empower those who have historically been the subjects of anthropological research, rather than researchers themselves. Designed in alliance with individuals who have borne the impact of marginalization, these partnerships bring together scholars and their interlocutors in an effort to expand anthropological knowledge, combat inequality, and help communities flourish. The program supports projects that will make a significant contribution to anthropological conversations through collaboration and engagement.

Anthropological research involves forging ethical relationships. Researchers must acknowledge the contributions of interlocutors and compensate them appropriately for their labor and time. Projects funded by Engaged Research Grants go even further. Not only are interlocutors participants in the research, but they have an active role in determining the problems explored. This grant program targets projects, growing out of a scholar’s established relationship with a community, that show greater potential when undertaken as a partnership, beginning with the formulation of research questions and extending to data gathering, skill sharing, scholarly communication, and public mobilization. Engaged research occurs in a broad range of settings, including communities, courtrooms, government offices, and laboratories. It results in findings that are meaningful and potentially transformative for research participants and others with a stake in the collaboration. Through this program, the Foundation seeks to demonstrate how engagement can foster innovation and further anthropological knowledge.

Award Money

The maximum Engaged Research Grant is $25,000. There is no limit to the duration of the grant, and applicants may request funding to cover distinct research phases (for example, two summers) if this is part of the research design.

About Us

Our Mission

The Marfan Foundation drives research, education and support – and builds community – to improve outcomes, save lives and empower all people to thrive who are living with Marfan, Loeys-Dietz, Vascular Ehlers-Danlos syndromes, and related genetic aortic and vascular conditions.

Our Vision

Quality of life, longevity, and cures for all people with genetic aortic and vascular conditions.

Career Development Award

The Career Development Award will support two-year $100,000 grants ($50,000 per year) in basic, translational, or clinical research studying any discipline involved in Marfan syndrome, Loeys-Dietz syndrome, Vascular Ehlers-Danlos syndrome, and other related conditions. This grant program is designed to support investigators early in their career to derive preliminary data in a key concept area that has high potential to lead to extended funding from NIH, EU, and other large research funding sources.

Unless noted otherwise in the scholarship description and criteria statement, applicants can attend accredited schools of their choice within the United States.

CFNJ scholarships awards vary. On average, awards range from $500 to $2,500. However, the award could be larger based on the number of qualified applicants and the parameters set by donors who have established the funds. 

James L. and Ruby L. Murray Memorial Scholarship

This scholarship will be awarded to a college-bound, graduating senior from one of the following high schools: Trenton High School, Ewing High School, Cherry Hill High School West, or East Orange High School. Applicants must be pursuing a bachelor’s degree in history, social science, or political science at any college/university of their choice within the United States. Students also must have achieved a cumulative 3.0 GPA or better.

The Hackensack Lakes Area Community Foundation, under the Initiative Foundation, provides grants to empower Central Minnesota communities. It focuses on projects that promote community development, environmental sustainability, and health. Eligible applicants include 501(c)(3) nonprofits and government units serving the Hackensack area. The foundation encourages collaboration with local organizations for innovative ideas, ensuring a lasting culture of generosity. Applications are accepted continuously, with quarterly awards based on a competitive review.

The Delano Area Community Foundation Grant aims to strengthen communities through local philanthropy. Established in 2014, it focuses on creating a sustainable funding source for community needs. The foundation invites 501(c)(3) nonprofits, government units, and public schools in the Delano area to apply for grants that enhance education, promote development, and enrich cultural activities. With over $10,000 awarded since its inception, it fosters community engagement and supports impactful projects.

The Lenora Jane Perdue Scholarship, offered by the North East Community Foundation, supports graduating seniors from Westfield Academy, Ripley Central School, and North East High School pursuing a degree in education. Applicants must maintain a GPA of 3.0 or higher. This scholarship aims to encourage and assist students dedicated to a career in teaching, fostering the next generation of educators in their community.

The Albany Area Education Foundation (AAEF) provides grants to faculty, staff, and administrators in the Albany Area Schools to enhance educational experiences. The foundation focuses on creating unforgettable learning opportunities, integrating advanced technology, and collaborating with community members to offer hands-on vocational training. By securing private funding, AAEF aims to innovate and expand academic, artistic, and athletic programs for students, ensuring a well-rounded educational environment.

The Radiation Exposure Screening and Education Program aims to support organizations in their efforts to screen and educate individuals who have been exposed to radiation from uranium mining and U.S. nuclear weapons testing. This initiative emphasizes the importance of awareness and education in mitigating health risks associated with radiation exposure, ensuring affected communities receive the necessary resources and support for health management.

The Jim and Shirley Cook Scholarship offers a $750 award for graduating high school seniors pursuing higher education at accredited institutions. Applicants must demonstrate financial need through FAFSA-SAI and provide evidence of community service and extracurricular involvement. Preference will be given to candidates with leadership experience in FFA or the GO CAPS program, specifically those studying Mechanical Engineering, CNC programming, Welding, or Machine Tool Technology. This scholarship aims to support students who embody commitment and community engagement.

Investing in research and healthcare to prevent, treat, and heal firearm-related harms

Kaiser Permanente Center for Gun Violence Research and Education

Kaiser Permanente established this Center in 2022 to scale its longstanding commitment to help communities prevent, treat, and heal from firearm-related injuries or death. The Center’s focus on violence prevention is rooted in healthcare, care delivery, and clinical interventions.

The Center is coordinated in collaboration with the Health Alliance for Violence Intervention (HAVI).

Research to support more effective health interventions

The Center funds research to test and expand health interventions that treat and prevent firearm injuries and deaths. This approach uses the same rigor and expertise that has helped treat and prevent other leading health concerns and causes of death, such as stroke, cancer, and heart disease. Funding supports projects to:

• Identify and evaluate health system strategies to address firearm injury and death, especially in communities that are most impacted.
• Test clinical interventions to prevent, treat, and heal trauma caused by firearm injuries and death.
• Assess pathways to implement and scale clinical interventions for firearm injury prevention in various healthcare settings.
• Improve healthcare identification and engagement of individuals at high risk of firearm injury or death.

Since its inception, the Center has awarded more than $8.5 million through 49 grants across 25 states and Washington, D.C., to advance research, capacity building, narrative change, and education.

Funding Opportunity

The call is open to applicants at varying stages of the research continuum. It is expected that central to all proposed initiatives are efforts to meaningfully engage communities that have been the most impacted by firearm violence.

What Work Will Be Considered for Funding?

Funding is currently available in two categories: Category 1 - Research Capacity Building; Category 2 - Pilot or Formative Healthcare Research

Category 2 - Pilot or Formative Healthcare Research

Up to two (2) projects will be selected, each receiving up to $250,000 over two (2) years.

Expand or pilot new research on evidence-informed healthcare practice or clinical care models that address firearm violence or firearm suicide.

Investing in research and healthcare to prevent, treat, and heal firearm-related harms

Kaiser Permanente Center for Gun Violence Research and Education

Kaiser Permanente established this Center in 2022 to scale its longstanding commitment to help communities prevent, treat, and heal from firearm-related injuries or death. The Center’s focus on violence prevention is rooted in healthcare, care delivery, and clinical interventions.

The Center is coordinated in collaboration with the Health Alliance for Violence Intervention (HAVI).

Research to support more effective health interventions

The Center funds research to test and expand health interventions that treat and prevent firearm injuries and deaths. This approach uses the same rigor and expertise that has helped treat and prevent other leading health concerns and causes of death, such as stroke, cancer, and heart disease. Funding supports projects to:

• Identify and evaluate health system strategies to address firearm injury and death, especially in communities that are most impacted.
• Test clinical interventions to prevent, treat, and heal trauma caused by firearm injuries and death.
• Assess pathways to implement and scale clinical interventions for firearm injury prevention in various healthcare settings.
• Improve healthcare identification and engagement of individuals at high risk of firearm injury or death.

Since its inception, the Center has awarded more than $8.5 million through 49 grants across 25 states and Washington, D.C., to advance research, capacity building, narrative change, and education.

Funding Opportunity

The call is open to applicants at varying stages of the research continuum. It is expected that central to all proposed initiatives are efforts to meaningfully engage communities that have been the most impacted by firearm violence.

What Work Will Be Considered for Funding?

Funding is currently available in two categories: Category 1 - Research Capacity Building; Category 2 - Pilot or Formative Healthcare Research

Category 1: Research Capacity Building

Up to two (2) projects will be selected, each receiving up to $100,000 over two (2) years.

Build capacity within the organization, institution, and/or clinical care setting to conduct research on healthcare approaches to addressing firearm violence or firearm suicide.

The Pillager Education Foundation Grant supports student excellence in academics, arts, athletics, and community activities through innovative funding. As a Partner Fund of the Initiative Foundation, it manages contributions to enhance educational opportunities and community engagement. Interested applicants should contact the fund's advisory team for guidance on the application process. This grant aims to empower students and enrich their learning experiences, ensuring sustainable support for future generations.

The Survivor Fellowship Program for Students, initiated by Everytown for Gun Safety in 2015, empowers individuals directly affected by gun violence. This year-long volunteer advocacy training helps survivors share their narratives, fostering awareness and mobilizing communities to combat gun violence. Participants must be at least 18 years old and enrolled in an educational institution, with a personal connection to gun violence, ensuring diverse experiences are represented in this impactful initiative.

Better World Scholarship Fund

The scholarship encourages women to acquire a degree in a science, technology, engineering, or math (STEM) field. The donor’s bachelor’s degree is in mathematics, followed 15 years later with a master’s degree in business administration. Her degree in mathematics provided opportunities for jobs in software development and application, medical research, technical documentation, organizational education and training, scientific research, and business. Her career was challenging, dynamic, encouraged creativity, never boring, offered schedule flexibility that allowed her to parent her four children, provided career choice independence, and was lucrative. Go STEM Girls!

Award Amount:

• Minimum $1,000

The MPS Physics Research Programs, funded by the National Science Foundation (NSF), support transformative research in various fields of physics. This includes experimental and theoretical work in atomic and molecular physics, particle physics, gravitational physics, and more. The NSF aims to promote ambitious projects without the need for immediate commercialization, focusing instead on foundational advancements that push the boundaries of our understanding of the universe.

The B. Charles Tiney Memorial ASCE Student Chapter Scholarship, established in 1980 by Mrs. Hazel M. Tiney, provides financial support to deserving undergraduate civil engineering students. This scholarship aims to assist with tuition expenses for those enrolled in ABET-accredited programs. Recipients are chosen based on their commitment to the civil engineering field and must be members in good standing of the American Society of Civil Engineers and their respective student chapters.

Ann Query Scholarship

Graduating senior who attends public, private, or home school and resides in the Zeeland Public School District area (student does not have to attend Zeeland Public Schools to be eligible)

The Schmeeckle Private Foundation Grants aim to enrich lives in Martin County, Minnesota, by supporting initiatives in early childhood education, resources for the elderly and disabled, and enhancing arts opportunities. The foundation honors Juanita Ellen Schmeeckle's legacy by providing matching grants to 501(c)(3) organizations, ensuring that local communities thrive through innovation and collaboration. This commitment to social betterment fosters a brighter future for all residents.