Best Large Grants for Nonprofit Organizations in Minnesota

The Whitehall Foundation offers research grants to support innovative and scientifically meritorious projects in neurobiology, focusing on sensory and motor functions in both invertebrates and vertebrates. Grants are aimed at independent investigators at accredited institutions in the U.S., with a maximum duration of three years, and a competitive renewal option available. Emphasis is placed on aiding early-career scientists and those transitioning into new research areas, fostering a diverse scientific community.

Marion Community Foundation

Since 1998, area residents have been turning to Marion Community Foundation to make their philanthropic giving as effective as possible. We are a public charity serving thousands of people who share a common concern … improving the quality of life in Marion County. We use distributions from the more than 500 charitable funds — created by generous, local donors — to award more than $2.5 million in grants and scholarships each year to many of the humanitarian, educational and cultural organizations in this remarkable community we call home.

Marion Community Foundation is the area’s leading philanthropic organization, providing charitable donors the opportunity to easily create endowment funds to benefit and support our community through grants and scholarships. We serve communities throughout Marion County through philanthropy, leadership, and civic engagement.

Clare Cooke Performing Arts Scholarship

Clare Cooke, the namesake of this fund, has worked as a performer, choreographer, and director for the Marion Palace Theatre since 1977, directing Christmas at the Palace and numerous community theater productions and junior musicals for many years, including The Wizard of Oz, The Will Rogers Follies, Annie, Oliver!, The Music Man, Guys and Dolls, Hairspray, and Oklahoma!

The Clare Cooke Performing Arts Scholarship Fund, created in 2012 through gifts from nearly 100 friends and family members, recognizes her outstanding contributions to the performing arts community and quality of life in Marion.

The Cooke Fund awards scholarships to Marion County high school seniors and graduates pursuing an education in the performing arts. Recipients are high school seniors who rank in the top 50th percentile of their graduating class or graduates with a college GPA of at least 2.5.

The Reading is Fundamental Matching Grant for Read for Success empowers local organizations to enhance literacy by providing matching funds for books and resources. Since 1966, RIF has partnered with communities to foster a culture of reading among children in need, offering diverse books that reflect their lives. This grant matches local investments dollar-for-dollar, maximizing the impact of funding for educational programs. Eligible applicants include schools and youth-serving organizations across the U.S., supporting children from birth through grade 12.

Vitamin Angels offers grants to US-based organizations dedicated to improving nutrition for pregnant women, infants, and young children. By providing prenatal multivitamins and technical support, the initiative aims to reach underserved communities facing nutritional barriers. Eligible organizations must serve at least 500 children or 100 pregnant women annually and distribute the vitamins without financial support from Vitamin Angels. This collaborative effort enhances health outcomes for vulnerable populations across the nation.

South Dakota Community Foundation

As a statewide community foundation, we work with donors, nonprofits and community leaders to strengthen philanthropy in South Dakota every day.

Scholarships

At South Dakota Community Foundation (SDCF), we proudly manage more than 350 scholarship funds in partnership with generous donors who are committed to supporting students. These scholarships offer countless opportunities to help ease the financial burden of continuing their education.

Wilmer & Esther Werner Family Scholarship

To provide financial support to graduates who plan to attend a college or technical school.

Grants Program for Penn Investigators - Faculty Awards

Research grant applications in basic science, prevention, disease interception, and early detection that are relevant to the study of BRCA1/2 will be considered. The Basser Cancer Interception Institute focuses on funding new endeavors in emerging, orthogonal fields beyond DNA damage (e.g. mechanisms of haploinsufficiency, cancer evolution and tissue tropism). 

Grants focused on the following are of particular interest:

• Cancer interception and the pre-cancer disease state
• Issues relevant to men (including but not limited to prostate cancer, pancreatic cancer, male breast cancer)
• Potential for translation into clinical practice
• Early detection

Grants that demonstrate a potential for translation into clinical practice will be prioritized for funding.

Faculty Awards

Faculty awards are for two years with a funding level up to $200,000 per year.

Community Foundation of the Holland/Zeeland Area

Our Mission

The Community Foundation of the Holland/Zeeland Area seeks to ensure that our community thrives today, tomorrow, and forever by building our Community’s Endowment to support high impact charitable projects, helping donors achieve their charitable goals, and leading and partnering in community-level initiatives.

Scholarships

CFHZ awards over $1 million in scholarships each year for students to attend schools of higher education throughout the nation. Our scholarships are possible thanks to the generosity of donors who invest in our community’s future by furthering the education of others.

All Holland/Zeeland area individuals interested in post-secondary education are encouraged to apply for CFHZ scholarships.

The Foundation proudly administers over 100 scholarships, each with unique eligibility criteria that must be met before a candidate can be considered.

DeLong and Brower, P.C. Scholarship

• Graduating senior, graduating early college student, or college freshman or sophomore who attends/attended public, private, or home school in the primary service area of the Community Foundation
• Enrolling/enrolled in a 2 or 4-year degree program at an accredited post-secondary school (including vocational/technical school) within the United States
• Financial need (must submit the page of the FAFSA Submission Summary showing the Student Aid Index amount)
• GPA of 3.0 or greater
• Planning to study accounting, finance, or economics
• Potentially renewable for one additional year

About American College of Radiology

Founded in 1923, the American College of Radiology® (ACR®) is at the forefront of radiology evolution, representing more than 40,000 diagnostic and interventional radiologists, radiation oncologists, nuclear medicine physicians and medical physicists.

Richard L. Morin, PhD, Fellowship in Medical Physics

The American College of Radiology® (ACR®) is proud to support the development of young medical physicists through the Richard L. Morin, PhD, Fellowship. This fellowship provides one or two medical physics residents the opportunity to gain hands-on experience with the ACR.

Morin fellows interact with College staff, gain governance experience and receive fully funded attendance to the ACR Annual Meeting at the end of their Fellowship year.

In addition, the ACR will fully fund a one-week trip to ACR headquarters in Washington, DC, during the fall of their fellowship year, for the fellow(s) to meet College staff across departments and projects.

Fellows who publish an article or complete a project will earn a stipend of $500.

The Sagol Network GerOmic Award for Junior Faculty supports early career investigators in aging research, focusing on -omics studies related to biological aging and age-related diseases. Research areas include genomics, proteomics, and interventions targeting aging. Eligible applicants are independent researchers at U.S. not-for-profit institutions, with 10 years or fewer since their postdoctoral training. The award may cover overhead costs, promoting innovative research in the vital field of gerontology.

The Republic Services Community Grant Program supports local nonprofit organizations focused on neighborhood revitalization, safety, disaster relief, and social services. Eligible 501(c)(3) organizations can apply once annually through an online application process. The program emphasizes a non-discrimination policy, ensuring services are provided without bias. However, funding is not available for individuals, government entities, schools, or religious organizations. This initiative reflects Republic Services' commitment to community engagement and support.

The AMVETS Spouse Scholarship offers financial support to the spouses of honorably discharged veterans and active military personnel, including National Guard and Reserves. This scholarship aims to bridge financial gaps after other federal and state resources have been exhausted. Eligible applicants must be U.S. citizens enrolled in accredited undergraduate programs, demonstrate financial need, and not be in default on federal student loans. AMVETS stands committed to empowering military families through education.

The NFL Foundation Grassroots Program, in partnership with the Local Initiatives Support Corporation (LISC), aims to enhance the quality, safety, and accessibility of community football fields. With grants up to $250,000, this initiative addresses the critical lack of safe recreation spaces in low-income neighborhoods, ensuring children and adults have access to well-maintained facilities for gathering and exercise, ultimately fostering community health and well-being.

Northern Chautauqua Community Foundation

Vision: We envision a vibrant, prosperous northern Chautauqua community, rich in opportunity today and tomorrow.

Our Mission

To realize our vision we focus on:

• strategic and responsive grant making
• encouraging local philanthropy and building permanent endowments for the future
• actively serving as a community leader and partner for the benefit and enrichment in our community.

Scholarships

Northern Chautauqua Community Foundation proudly manages over 200 individual scholarship funds,

Roger Testrake Memorial Scholarship

The Roger Testrake Memorial Scholarship benefits students residing in Ripley, NY who plan on continuing their education after high school and have a relative who has served in the military.

Roger Testrake was instrumental in building a monument in Ripley to honor all veterans. This scholarship was renamed to honor him for all his perseverance, dedication and hard work on behalf of the Ripley Veterans Roll of Honor Organization. 

Scholarships support aspiring college students who hold the promise of tomorrow’s progress.

Together, our competitive grants and scholarships help our region rise thanks to the vision and generosity of our donors.

Theodore Satter Memorial Scholarship Fund

• Must major in business, banking, or finance.
• Not based on financial need.

The McCarthey Dressman Education Foundation offers Teacher Development Grants to support K-12 educators in enhancing their classroom instruction. With grants up to $10,000 per year, individuals or small teams can implement innovative teaching strategies that foster critical inquiry and improve student engagement. This initiative aims to boost educational experiences for diverse learners, encouraging teachers to document and share their methods, ultimately promoting a culture of continuous professional growth.

Northern Chautauqua Community Foundation

Vision: We envision a vibrant, prosperous northern Chautauqua community, rich in opportunity today and tomorrow.

Our Mission

To realize our vision we focus on:

• strategic and responsive grant making
• encouraging local philanthropy and building permanent endowments for the future
• actively serving as a community leader and partner for the benefit and enrichment in our community.

Scholarships

Northern Chautauqua Community Foundation proudly manages over 200 individual scholarship funds,

Timothy Ryan Memorial Scholarship

The Timothy Ryan Memorial Scholarship Fund provides scholarships to students who exemplify characteristics exhibited by Timothy during his brief life: loving, caring, generous, family-oriented, genuine, sincere, and humorous.

Northern Chautauqua Community Foundation

Vision: We envision a vibrant, prosperous northern Chautauqua community, rich in opportunity today and tomorrow.

Our Mission

To realize our vision we focus on:

• strategic and responsive grant making
• encouraging local philanthropy and building permanent endowments for the future
• actively serving as a community leader and partner for the benefit and enrichment in our community.

Scholarships

Northern Chautauqua Community Foundation proudly manages over 200 individual scholarship funds,

St. Joseph School Scholarship

The St. Joseph School Scholarship is awarded to a graduating senior who resides in northern Chautauqua County, and intends to pursue a career teaching children with special needs.

Scholarships support aspiring college students who hold the promise of tomorrow’s progress.

Together, our competitive grants and scholarships help our region rise thanks to the vision and generosity of our donors.

Frances F. Bourque Scholarship Fund Endowment established by Old School Square Center for the Arts

This scholarship honors Frances Bourque’s extraordinary legacy by nurturing the next generation of arts visionaries. It exists to ignite in young people the same passion for creative expression and cultural preservation that has defined Frances’s remarkable life of service.

The Fiscal Year 2027 Regional Nutrition Hubs initiative by the US HHS aims to enhance nutrition services across regional health centers. By providing targeted technical assistance, the program seeks to improve health outcomes through effective nutritional interventions. This initiative supports HRSA's mission to expand access to high-quality healthcare services, ultimately benefiting communities by addressing dietary needs and managing health conditions. With a focus on collaboration, the program is set to strengthen the health infrastructure at the local level.

Northern Chautauqua Community Foundation

Vision: We envision a vibrant, prosperous northern Chautauqua community, rich in opportunity today and tomorrow.

Our Mission

To realize our vision we focus on:

• strategic and responsive grant making
• encouraging local philanthropy and building permanent endowments for the future
• actively serving as a community leader and partner for the benefit and enrichment in our community.

Scholarships

Northern Chautauqua Community Foundation proudly manages over 200 individual scholarship funds,

Rev. Clifford K. Cliver & Lucy Cliver Sumsky Scholarship

The Rev. Clifford K. Cliver & Lucy Cliver Sumsky Scholarship Fund acknowledges and supports Chautauqua County foster children by providing scholarships for continuing education.

Northern Chautauqua Community Foundation

Vision: We envision a vibrant, prosperous northern Chautauqua community, rich in opportunity today and tomorrow.

Our Mission

To realize our vision we focus on:

• strategic and responsive grant making
• encouraging local philanthropy and building permanent endowments for the future
• actively serving as a community leader and partner for the benefit and enrichment in our community.

Scholarships

Northern Chautauqua Community Foundation proudly manages over 200 individual scholarship funds,

Dunkirk Area Labor Council Scholarship

The Dunkirk Area Labor Council Scholarship supports graduating students who are furthering their education in the trades or manufacturing technology.

Northern Chautauqua Community Foundation

Vision: We envision a vibrant, prosperous northern Chautauqua community, rich in opportunity today and tomorrow.

Our Mission

To realize our vision we focus on:

• strategic and responsive grant making
• encouraging local philanthropy and building permanent endowments for the future
• actively serving as a community leader and partner for the benefit and enrichment in our community.

Scholarships

Northern Chautauqua Community Foundation proudly manages over 200 individual scholarship funds,

David J Lewandowski Memorial Award

The David J Lewandowski Memorial Award is presented to a graduating senior from Dunkirk, Forestville, or Fredonia who is entering a career in the trades, agriculture, conservation, forestry, or emergency services.

The Dallas Geological Society Scholarship, managed by the Communities Foundation of Texas, provides one-year awards of up to $5,000 to undergraduate and graduate students majoring in Geological Sciences. Applicants must be U.S. citizens or documented residents, residing in the Dallas area, with a minimum GPA of 3.0. Preference is given to those who have completed core geology courses. This scholarship supports the development of future leaders in the geosciences.

The AMVETS Veteran, Active Duty & Guard/Reserve Scholarship provides financial assistance up to $12,000 for qualified U.S. Veterans and active military members pursuing undergraduate degrees. This scholarship is designed to bridge the financial gap after all other federal and state aid has been utilized. Eligibility includes being an honorably discharged veteran or active service member, enrolled in an accredited institution, and demonstrating financial need. AMVETS is dedicated to serving those who have served our country.

Learning from Abroad to Reimagine Health Knowledge Systems for Equity and Wellbeing Grant

The Robert Wood Johnson Foundation (RWJF) is committed to dismantling structural racism and eliminating barriers to health equity by working alongside communities, practitioners, and institutions. One way we support this mission is by investing in the knowledge of historically marginalized communities and deepening the relationships that build community power, evidence, and systems of change. Another way we do this is by looking beyond the U.S. borders. The Global Ideas for U.S. Solutions team looks abroad for ideas to improve health equity, justice, and wellbeing in the U.S.  

This funding opportunity invites organizations to learn and produce solutions to build a more inclusive and equitable health knowledge system, inspired by other countries that have faced or are currently facing similar health equity challenges. It allows organizations to learn from efforts outside of the U.S. to reimagine and rebuild the health knowledge system in ways that can withstand systemic threats while advancing health equity and wellbeing for the future. Among many other characteristics yet to be identified, our learnings to date suggest that the following contribute to this reimagined version of the health knowledge system:  

• The experience of people most affected by health inequities is centered in the generation of data and evidence and in policymaking;
• Health is more than the absence of disease. It is about individual and collective healing and wellbeing;
• Mis- and disinformation are eliminated and public trust in science and evidence is restored;
• History, culture, and language are preserved and protected, and ecological and biomedical sciences are braided with Indigenous, traditional, holistic, and community frameworks; and
• Cross-sector approaches and global learning networks break down siloes and allow for more effective and equitable solutions. They leverage lessons from resistance movements and connect artists, researchers, public health, and civil society.

The purpose of this CFP is to support organizations in pursuing action-oriented projects that leverage learning from outside the U.S. to create a more durable and equitable health knowledge system in the U.S. These efforts will advance health equity, justice, and wellbeing through community-driven knowledge generation, preservation, and narrative. Together, these actions lay the foundation for a more inclusive, equitable, and resilient health knowledge system in times of crisis and beyond. 

Total Awards

Type of Award: Awards will be structured as grants and will be made to organizations, not to individuals.

• Number of Awards: Up to 15 awards will be funded.  
• Amount of Award: Awards will be up to $500,000 each. Please request only what is necessary to allow us to fund as many recipients as possible. We expect larger awards to correspond with more distributed funding (e.g., multiple people’s salaries or multiple activities). See more information on RWJF budget categories and allowable costs here.  
• Award Duration: Awards will be up to 36 months.  

Real World Evidence on clinical outcomes with Aztreonam-Avibactam (ATM-AVI)

This RFP invites research proposals aimed at assessing clinical outcomes associated with the use of Aztreonam-Avibactam (ATM-AVI) in real world clinical settings.

In scope are adult patients with suspected or documented infections due to aerobic gram negative organisms. Eg. CRE-MBL, Stenotrophomonas maltophilia, treated with ATM-AVI.

Geographic Scope

Countries where ATM-AVI is available (ex-US) and used in clinical practice at the time of RFP release, including but not limited to parts of EU, the United Kingdom, the Middle East, and selected Asia-Pacific markets. Proposals from institutions already participating in Pfizer-sponsored or funded, overlapping ATM-AVI RWE study may be considered out of scope. Proposals involving studies on patients that have received ATM-AVI via pre-approval or pre-launch expanded access routes may be considered out of scope

Project Types and Area of Interest

Potential applicants are requested to submit research proposals to study the below outcomes following treatment with ATM-AVI for adult patients with suspected or documented infections with aerobic gram negative organisms e.g. CRE-MBL, S. maltophilia.

• Clinical effectiveness with ATM-AVI
• Safety outcomes with ATM-AVI
• Microbiological outcomes with ATM-AVI
• Health Economic outcomes with ATM-AVI (in addition to any of the above)

Proposals may include data from special populations such as – immunocompromised (solid organ transplant or haemato-oncological patients)

Funding Range and Project Length

• Individual projects requesting up to $50,000 USD will be considered. The total budget for this RFP is $ 250,000 USD
• Maximum project length is 12 months

The Community Foundation of NCW is a tax-exempt philanthropic organization that helps individuals, families, businesses, and agencies support charitable causes throughout Chelan, Douglas, and Okanogan counties.

Jerry Van Winkle Memorial Scholarship

Jerry Van Winkle always considered himself a lifelong learner. One of his finest qualities was the ability to find a way to achieve his goals. He pursued his desire to become a counselor, beginning his Masters’ Degree studies at age 55. Jerry’s greatest joy was in helping students see the possibilities that education could provide. He would be honored to know that his wish – to assist students in pursuing their education – will be carried out through this scholarship fund. Each year this scholarship honors a student that demonstrates financial need, strong moral character, and personal growth throughout high school.