Best Large Grants for Nonprofit Organizations in Minnesota

The MRAC: Next Step Fund Grant, supported by the McKnight Foundation, offers project grants of up to $6,000 for artists across all disciplines. This initiative aims to assist artists in overcoming barriers to success, sustaining their artistic careers, and seizing future opportunities. Open to applicants at any career stage, projects should reflect individual goals and career stages, fostering both advancement and maintenance of creative practice.

Nestlé Purina offers pet food donations and disaster relief primarily to 501(c)(3) tax-exempt pet welfare organizations in the U.S. Their commitment includes supplying food and litter to over 900 organizations, reflecting their dedication to the well-being of pets and communities. Purina also assists during natural disasters, providing essential support to pets in distress. Organizations interested must ensure eligibility and can expect a decision within 10 business days after application submission.

The Wag Wine Operation supports no-kill adoption groups by providing grants ranging from $250 to $1000. These funds assist organizations in purchasing essential supplies, food, and medical care for adoptable pets. Offered by the Petfinder Foundation, this initiative aims to keep homeless animals healthy and facilitate their transition to loving homes. Grants are awarded monthly until funds are depleted, with the program benefiting over 10,000 adoption groups across North America.

The Zeller Summer Scholarship in Medicinal Botany, initiated by the Garden Club of America, supports US undergraduate students pursuing summer studies in medicinal botany. Established in 2003 in honor of Caroline Brown's family, the scholarship encourages students to engage in various educational projects and internships. Eligibility includes enrollment in an accredited US college, with restrictions on international applicants. This initiative fosters knowledge in the field, promoting environmental awareness and academic excellence.

The NIDCR Small Grant Program for New Investigators (R03) supports early-stage scientists in dental and craniofacial research. It funds pilot studies and developmental projects aimed at generating preliminary data for future Research Project Grant (R01) applications. Key deadlines for applications include February 16, June 16, and October 16 from 2025 to 2027, addressing the need for timely submissions in this competitive funding landscape.

The PEN/Jacqueline Bograd Weld Award for Biography, presented by PEN America, recognizes outstanding literary works in biography published in the U.S. during the previous year. With a prize of $5,000, this award celebrates authors who demonstrate exceptional narrative and artistic merit through scrupulous research. Since its inception, PEN America has awarded over $370,000 annually, supporting diverse voices in literature and promoting the freedom of expression.

The Marlène F. Johnson Fund for Scholarly Research on Christian Science offers grants up to $20,000 for scholarly projects focusing on Christian Science history, teaching, and practice. Open to all individuals, the fund seeks to promote serious research, encouraging engagement from both scholars and the public. The initiative reflects a commitment to insightful scholarship rather than mere religious apologetics, ensuring a respectful approach to the study of this faith tradition.

The PEN/E.O. Wilson Literary Science Writing Award honors outstanding writing that effectively communicates complex scientific ideas in an accessible manner. Established by Dr. Edward O. Wilson and supported by notable figures, this award recognizes a single, living author for their work published within the calendar year. The winner receives a $10,000 cash prize, celebrating excellence in the literature of the physical and biological sciences.

The ADEAGies Foundation Grant supports oral health innovations and the development of future leaders in academic dentistry. Funded by the ADEAGies Foundation, the program offers annual grants ranging from $10,000 to $50,000 for various dental programs and initiatives. The Board of Trustees evaluates proposals each March, aiming to fully fund as many projects as possible while reserving the right to offer partial funding. Grants are awarded annually to qualifying organizations.

The Onyx & Breezy Foundation Grant provides financial support to animal welfare organizations in need. By leveraging funds from generous donors, the foundation aims to help various initiatives, including medical treatment, spay and neuter services, and providing pet food. Eligible applicants must demonstrate non-profit status, while capital improvements and previously covered medical care are excluded from funding. For more details, please refer to the FAQs on their website.

The Armstrong Foundation, established in 1949, focuses on funding educational initiatives that promote the significance of the U.S. Constitution. To be eligible, organizations must provide an IRS determination letter confirming their 501(c)(3) status. This foundation aims to enhance public understanding and appreciation of constitutional values through various educational mediums.

The Aging Services Leadership Fellowship, offered by the United Negro College Fund, is a one-year non-clinical program for recent master's graduates or mid-career professionals with at least five years of experience. The program emphasizes cohort learning, community building, and skill development in aging services. Participants engage in specialized training, networking events, and mentorship opportunities designed to foster leadership and cultural humility, ultimately preparing them to lead in the aging services sector.

The PEN/Diamonstein-Spielvogel Award for the Art of the Essay, established by PEN America, honors a distinguished writer whose collection of essays expands their body of work. This prestigious award, with a cash prize of $15,000, recognizes books of individual essays that can explore a specific theme or a variety of subjects. Eligible candidates must be U.S. residents and cannot be debut authors, ensuring the award celebrates established voices in the literary community.

The PEN/Voelcker Award for Poetry Collection, established by a bequest from Hunce Voelcker, is presented annually by PEN America to recognize a distinguished collection of poetry published in the calendar year. This award honors the importance of poetry collections as an art form and is open to all U.S. residents or citizens, regardless of age or poetic style, with a cash prize of $5,000. It aims to celebrate and expand the scope of American poetry.

The Infant-Toddler Court Program's National Resource Center (NRC) focuses on enhancing child welfare practices across the United States. By collaborating with courts, social services, and families, the NRC aims to improve the safety and healthy development of young children involved with the child welfare system. This initiative not only supports families but also fosters nurturing relationships essential for child growth and well-being, making it a crucial resource for communities.

The Infant-Toddler Court Program State Awards empower states and communities to enhance child welfare practices by integrating courts, social services, and families. This initiative promotes safety, healthy development, and nurturing relationships for young children involved in child welfare. Awardees implement the evidence-based ITC approach, sharing lessons learned with local teams, tracking outcomes, and training to ensure effective program expansion across targeted communities.

The Site-Based Clinical Training Grant Program, administered by the Minnesota Department of Health, aims to enhance clinical healthcare training throughout Minnesota. With a funding estimate of $4,657,000 for FY 2026, this grant prioritizes rural primary care and oral health training. Eligible applicants include clinical training sites actively enrolled in the Minnesota Health Care Program, which must demonstrate their commitment to addressing healthcare shortages in underserved areas. This initiative supports the development of a skilled healthcare workforce.

The DTA Foundation: Dental Hygiene Scholarship, in partnership with the Benco Family Foundation, provides up to $10,000 to dental hygiene students from underrepresented backgrounds. This initiative honors Lawrence and Sally Cohen's contributions to the field. With a generous $1M endowment, the scholarship aims to support aspiring dental hygienists, ensuring increased accessibility to the profession and recognizing those who demonstrate passion and commitment to dental care.

The Coupling, Energetics, and Dynamics of Atmospheric Regions (CEDAR) program, funded by the National Science Foundation, aims to enhance our understanding of atmospheric behaviors from the middle atmosphere to the exosphere. It supports research into coupling, energetics, and dynamics, particularly how lower atmospheric perturbations and solar inputs affect the upper atmosphere. The program encourages innovative approaches, including AI and machine learning, to advance observational and theoretical studies in this critical area of atmospheric science.

The JSF Scholarships aim to empower economically disadvantaged students by providing financial assistance for their education. This initiative addresses barriers to education and employment, enabling students to achieve academic success and meaningful careers. The Foundation supports various scholarship programs, partnering with schools and universities, and focusing on areas such as financial need and mentorship. By fostering educational opportunities, the JSF Scholarships contribute significantly to community development and individual empowerment.

The Berkshire Woodworkers Guild Scholarship offers financial support to aspiring professional woodworkers and designers. Established in 1998, this scholarship is funded through generous donations and proceeds from an annual silent auction. Recipients are encouraged to engage with the Guild and showcase their work at events. Preference is given to applicants pursuing comprehensive woodworking programs that lead to certification or degrees, but other professional development opportunities may also be considered.

The Live Your Dream Awards, sponsored by Soroptimist International of the Americas, empower women by providing vital monetary assistance for their education and training. Each year, over $3 million is awarded to more than 2,300 women who are the primary financial support for their families. This initiative supports those overcoming significant challenges like poverty and domestic violence, ensuring they have the resources to achieve their dreams and live fulfilling lives.

The Bring Back the Trades Scholarship is dedicated to addressing the skilled trades shortage by providing $1,500 monthly scholarships to students enrolled in post-secondary skilled trades programs across the United States. Founded by a seasoned business owner, the initiative aims to raise awareness and reshape perceptions of trade careers, ensuring that students have the resources to succeed in vital roles that contribute to the nation's future.

The Marine Trades Scholarship, offered by the National Marine Representatives Association (NMRA), supports students pursuing education in marine trades. Since 2008, NMRA has facilitated annual scholarships funded by members and affiliates. This initiative not only encourages academic growth but also fosters professional development through networking events, industry insights, and advocacy support. Applications are accepted each spring, with recipients chosen in the summer, promoting a brighter future for the marine industry.

The AAPD Foundation provides Access to Care Grants aimed at ensuring dental care is accessible for all children. As the largest dentist-led charity, it supports community programs that deliver essential dental services. With a focus on innovative ideas and effective grant utilization, the foundation works tirelessly to promote healthy smiles for every child. By partnering with pediatric dentists, it strives to make a meaningful impact in communities nationwide.

The College Now Greater Cleveland Manufacturing Scholarship offers financial assistance to high school graduates pursuing training in manufacturing. Awarded funds, up to $2000, are sent directly to educational institutions for related expenses. Applicants must reside in specific Ohio counties and be enrolled in eligible programs. This scholarship aims to support individuals seeking vocational training, certifications, or degrees within a two-year timeframe, fostering career development in the manufacturing sector.

The Transition to Aging Research Award for Predoctoral Students, funded by the National Institute on Aging (NIA), invites exceptional graduate students to pursue aging-related postdoctoral training. This two-phase award supports late-stage doctoral candidates in completing dissertation projects across diverse research areas. It aims to facilitate smooth transitions into competitive aging-focused postdoctoral roles, fostering the development of future investigators in aging research. This initiative is designed to enhance collaboration and impactful research in the field of aging.