Best Large Grants for Nonprofit Organizations in Minnesota

The Building Better Lives Grant, offered by the Northwest Minnesota Foundation, aims to empower local leaders and communities through innovative, community-led solutions. By prioritizing engagement, collaboration, equity, and sustainability, the grant supports projects that strengthen families, promote health and wellness, cultivate welcoming communities, enhance economic mobility, and build nonprofit capacity. Together, these efforts contribute to a more resilient and thriving region.

The Elliott Coues Award, presented by the American Ornithological Society, honors exceptional contributions to ornithological research without geographic or disciplinary restrictions. This prestigious award includes a medal and an honorarium and is named after Elliott Coues, a pioneering ornithologist. The award emphasizes the importance of diverse nominations and aims to recognize individuals who have made significant impacts in the field of ornithology, thus fostering a vibrant ornithological community.

The William Brewster Memorial Award, awarded by the American Ornithological Society, recognizes exemplary contributions to ornithological science through a significant body of work on Western Hemisphere birds published in the last decade. This prestigious award honors the legacy of William Brewster, a founding member of the American Ornithologists' Union, and includes a medal and honorarium funded by the William Brewster Memorial Fund. Nominations are open to all, fostering diversity in ornithology.

The Ralph W. Schreiber Conservation Award, presented by the American Ornithological Society (AOS), honors individuals or small teams for exceptional contributions to bird conservation. Recognizing efforts in applied research, habitat preservation, and educational initiatives, this award aims to encourage the scientific study of birds and promote ethical practices in ornithology. Nominees must be AOS members, ensuring a commitment to the society's mission of fostering a diverse and engaged ornithological community.

The Peter R. Stettenheim Service Award, established by the American Ornithological Society in 2018, honors individuals who have made significant contributions to ornithology and the society. This award recognizes those who have served in various capacities, highlighting volunteer work, mentorship, and committee involvement. It is named after Peter Stettenheim, a notable leader in ornithology, who was dedicated to advancing the field and supporting fellow ornithologists throughout his career.

The Marion Jenkinson Service Award, presented by the American Ornithological Society, honors early- and mid-career ornithologists for their extensive volunteer contributions and service to the society. This award includes a framed certificate and recognizes individuals who exemplify high ethical standards aligned with the AOS Code of Conduct. The award aims to foster a diverse and supportive ornithological community while promoting bird conservation and scientific study.

The Ned K. Johnson Early Investigator Award, presented by the American Ornithological Society, recognizes exceptional early-career researchers in ornithology. Awardees receive a certificate, a $1,500 honorarium, and complimentary registration for the annual meeting, where they can present a plenary. Candidates must have received their doctorate between 2019 and 2022, and demonstrate ethical standards aligned with the AOS Code of Conduct. This award fosters leadership and innovation in bird conservation and research.

The James G. Cooper Early Professional Award, presented by the American Ornithological Society, celebrates the achievements of early-career ornithologists. Awardees receive a certificate, a $1,500 honorarium, and free registration to the annual meeting, where they can present their research. Candidates are evaluated based on their CV and a mini-paper. This award aims to promote ethical research practices and leadership in ornithology, fostering a diverse and dynamic community of scientists dedicated to bird conservation.

The Loye and Alden Miller Research Award, presented by the American Ornithological Society, recognizes lifetime achievements in ornithological research. It honors the legacy of Loye Holmes Miller and his son Alden Holmes Miller, who significantly contributed to the field and mentored numerous students. This prestigious award aims to uphold high ethical standards in ornithology and is open to current AOS members, promoting a diverse and supportive community in bird conservation.

About Pfizer External Research & Grants

Pfizer External Research & Grants (ER&G) supports independent research, education, and QI initiatives to improve patient outcomes in areas of unmet need. Competitive grants are awarded through transparent RFPs reviewed by independent expert panels.

About ASCP

American Society for Clinical Pathology (ASCP) is the world’s largest professional membership organization for pathologists and laboratory professionals, with more than 100,000 members. ASCP provides excellence in education, certification, and advocacy on behalf of patients and the laboratory workforce. With a portfolio of more than 900 educational activities, ASCP is the worldwide leader in providing CME/CMLE credit for the entire laboratory team.

Quality Improvement in Molecular Testing Pathways for Metastatic Colorectal Cancer (mCRC)

The American Society for Clinical Pathology (ASCP), in collaboration with Pfizer Inc. and with participation from the American Society of Clinical Oncology (ASCO, invites proposals for pathology-centric Quality Improvement (QI) initiatives aimed at optimizing molecular testing pathways in the management of metastatic colorectal cancer (mCRC). This grant opportunity seeks to fund sustainable projects that improve biomarker testing practices, strengthen targeted therapy selection, and support care teams in implementing patient-centered protocols. 

The overarching goal of this program is to advance diagnostic excellence and improve treatment decision-making for patients with mCRC.

The Lazarus Family Scholarship in Bioethics and Humanities, offered by the AMA Foundation, supports students engaged in bioethics or the humanities, including art, music, and literature. This scholarship aims to foster the next generation of physician leaders by providing financial assistance to those who are committed to advancing health equity and community service. By recognizing diverse fields of study, it emphasizes the importance of interdisciplinary approaches in medicine and the humanities.

The KTGF Fellowship Programs, funded by the Klingenstein Third Generation Foundation, offer $100,000 over two years to support post-doctoral and junior faculty research on ADHD and depression in children, particularly from low-income and under-resourced backgrounds. This initiative aims to foster promising early-career scientists while producing impactful research that benefits affected children and families. Applications are accepted from September 1 to December 15, with specific eligibility criteria outlined for candidates.

Greater Toledo Community Foundation

Greater Toledo Community Foundation transforms generosity into lasting impact. With over $510 million in assets across 1,000+ funds, we've granted more than $370 million to strengthen education, health, arts, and social services throughout our region.

We connect donors with causes they care about while bringing together leaders, organizations, and resources to tackle our community's biggest challenges. What began with Walter E. Terhune's vision in the 1920s continues today as we help individuals, families, and businesses create positive change that will benefit our region for generations.

Ottawa County Community Foundation Grants

The Ottawa County Community Foundation, Inc. (OCCF) is a public charitable organization created by the citizens of Ottawa County to enrich the quality of life for individuals and families in Ottawa County. Grants from unrestricted funds support a variety of programs in the fields of education, health and social services, economic development, natural resources and the arts.

Sodexo Stop Hunger Foundation

The Sodexo Stop Hunger Foundation goes beyond food aid to create lasting change. Through innovative programs, strategic partnerships and volunteer action, Stop Hunger tackles the root causes of food insecurity.

In 2025, Sodexo Stop Hunger Foundation and the Hunger Center awarded grants to 131 programs representing 118 communities in 37 states plus the District of Columbia. Collectively, these programs provided an estimated 22,000 backpacks full of shelf-stable food items for students to take home for the weekend or holidays when school meals are not served.

Since 2006, the Sodexo Stop Hunger Foundation has been a driving force behind weekend and holiday hunger relief for students across the U.S. Through support of food backpack programs, the Foundation partners with local food banks and schools to discreetly provide K-12 students with backpacks filled with nutritious, shelf-stable meals. These backpacks are distributed in safe, familiar settings – typically on the last school day before a weekend or school break – ensuring that all children who rely on free or reduced-price school meals don’t go hungry when school is out.

K-12 Backpack Grant

The K-12 Backpack Grant is an initiative launched by the Sodexo Stop Hunger Foundation and administered in partnership with the Congressional Hunger Center to support community backpack programs. Grants of $1,000 will be issued to community organizations with established backpack feeding programs that provide students with shelf-stable, nutritious meals when school is out of session.

The Lifetime Contribution to the AAAAI and Allergy/Immunology Specialty Award honors individuals who have made significant and enduring contributions to the AAAAI and the allergy/immunology field. Awardees are recognized for exemplary service, leadership in professional organizations, impactful research, and mentorship of trainees. This prestigious accolade underscores the recipient's dedication to advancing the specialty and improving patient care, emphasizing the importance of community engagement and leadership in the field.

The Healthy American Forests Initiative, led by the National Fish and Wildlife Foundation (NFWF), aims to enhance forest health and resilience through targeted funding. This initiative anticipates awarding 10-15 grants ranging from $250,000 to $2 million, supporting projects up to 2 years in duration. A 20% non-federal match is required, and interested applicants are encouraged to collaborate with NFWF and Native Americans in Philanthropy for potential match funding.

About Us

advancing the science of water ®

Who We Are

The Water Research Foundation (WRF) is the leading research organization advancing the science of all water to meet the evolving needs of its subscribers and the water sector. WRF is a 501(c)(3) nonprofit, educational organization that funds, manages, and publishes research on the technology, operation, and management of drinking water, wastewater, reuse, and stormwater systems—all in pursuit of ensuring water quality and improving water services to the public.

5411 - Practical Playbook for Adaptive Utility Capital Improvement Planning Under Deep Uncertainty

Grant Information

• Assess current utility practices for incorporating adaptive or flexible decision making into capital improvement planning (CIP) at the portfolio or programmatic level.
• Identify where deep uncertainty most affects CIP decision points, including investment areas prone to lock-in or points of no return.
• Document the institutional processes, frameworks, and governance structures that have enabled utilities to embed adaptive and flexible investment strategies.
• Quantify how adaptive capital strategies compare to traditional CIP approaches in terms of lifecycle costs, rate stability, financial risk exposure, and avoided or deferred capital investments across a range of plausible future conditions.
• Establish practical criteria to help utilities determine which types of capital investments are well suited for adaptive approaches.
• Develop a practitioner-focused playbook that equips utilities to apply adaptive CIP in practice, including case studies, decision trees, trigger points, vulnerability assessment tools, financial and risk insights, and governance guidance.
• Produce tiered recommendations that allow utilities to adopt adaptive CIP practices incrementally.

About Us

advancing the science of water ®

Who We Are

The Water Research Foundation (WRF) is the leading research organization advancing the science of all water to meet the evolving needs of its subscribers and the water sector. WRF is a 501(c)(3) nonprofit, educational organization that funds, manages, and publishes research on the technology, operation, and management of drinking water, wastewater, reuse, and stormwater systems—all in pursuit of ensuring water quality and improving water services to the public.

5426 - Investigation of Non-Point Sources of PFAS in Sewersheds and Potential Mitigation Strategies

Grant Information

Evaluate the impact of non-point or dispersed sources of per- and polyfluoroalkyl substances (PFAS) in the sewershed (including PFAS-contaminated groundwater infiltration) on PFAS mass loading to wastewater treatment plants.

Assess how PFAS loading from non-point or dispersed sources of PFAS in the sewershed may affect treatment efficiency and reuse water quality.

Improve understanding of PFAS precursor contributions.

Identify potential strategies to mitigate PFAS loading from non-point or disbursed sources of PFAS in the sewershed.

The Enterprise Mobility™ Philanthropic Giving program focuses on enhancing community engagement through grants aimed at supporting health, education, arts, and disaster relief initiatives. Only Enterprise Mobility team members and their spouses or domestic partners who volunteer with a nonprofit can apply for funding. The program prioritizes sustainable projects that uplift local communities and address pressing social issues, fostering a culture of responsibility and giving back to society.

The American Heart Association is seeking proposals to study the prevalence and treatment of cardiovascular, kidney, and metabolic diseases among cancer patients and survivors. Given the over 16.7 million cancer survivors in the U.S., this research aims to highlight critical health disparities, identify treatment modalities, and explore shared risk factors. Applications focusing on underrepresented populations and utilizing real-world data sources are especially encouraged, aiming to improve health outcomes in this vulnerable group.

The Catalyze Challenge Grant, managed by Catalyze, is an opportunity for organizations to receive funding for innovative solutions that enhance career-connected learning for youth aged 11-22. With over $4 million available in Round 5, finalists can secure up to $300,000 to implement their ideas. The grant seeks proposals that empower underserved learners through hands-on experiences and meaningful employer partnerships, ultimately impacting over 65,000 young people across the U.S.

The National Child Traumatic Stress Initiative aims to enhance trauma-focused treatment and services for children and adolescents affected by traumatic events. By increasing access to these vital services, the initiative seeks to support families in overcoming the challenges posed by trauma. Eligible applicants include public and private nonprofit entities, ensuring a broad reach for effective intervention and support within communities.

The Eastern Bank Foundation (EBF) is dedicated to empowering communities through its Neighborhood Donations initiative. By investing over $16 million in local organizations, EBF aims to support vital services and promote equity in Eastern Massachusetts, Southern New Hampshire, and Rhode Island. This program allows contributions to non-501(c)(3) organizations, reinforcing EBF's commitment to partnership and community-driven solutions, with donations typically ranging from $100 to $1,000.

The Goldberg, Joseph and Ruth Scholarship, offered by the Beatrice Educational Foundation, aims to support students pursuing medical professions, such as nursing, dental, and physical therapy. Established in 1987, the Foundation provides over $55,000 annually in scholarships to Beatrice High School seniors. Eligible applicants must be in the top quarter of their class and complete the application independently. This scholarship is part of the Foundation's commitment to enhancing educational opportunities in the Beatrice School District.

The Dale Jr. Foundation is dedicated to empowering underprivileged youth through targeted support in five key areas: Empowerment, Education, Wellness, Hunger, and Hope. By providing safe homes, educational resources, and healthy food, the foundation helps children overcome adversity and achieve their dreams. Their commitment extends to various charities, ensuring that every child has the opportunity to thrive. The foundation emphasizes community support and holistic care, making a significant impact in the lives of many young people.

The SAF National Awards Program includes the Sir William Schlich Memorial Award, which honors exceptional contributions to forestry, particularly in policy and international activities. Presented biennially at the SAF National Convention, it features a $500 honorarium, complimentary registration, and up to $500 for travel expenses. This award commemorates Sir William Schlich's significant role in advancing forestry education and practices in the 19th century, promoting sustainable management of forest resources.

The BTCF: Simple Gifts Fund Grant supports young artists aged 13-19 in the Berkshire Taconic region, providing financial assistance for summer enrichment programs in the arts. Established in 1998 in memory of folk singer Bill Crofut, the fund aims to empower youth through small grants that can cover costs for tuition, art supplies, or living expenses. The grant fosters creativity and personal growth, ensuring that young individuals have opportunities to pursue their passions.