Best Large Grants for Nonprofit Organizations in Minnesota

The Joan L. Conroy Scholarship, established in 2024, supports Ph.D. nursing students dedicated to educating future nurses. It honors Joan L. Conroy's legacy, emphasizing her love for education and nursing. Applicants must have two semesters left in their program and demonstrate a commitment to geriatric nursing and home health care. This scholarship is funded by the Nurses Educational Funds Inc., a nonprofit organization that promotes nursing leadership through educational scholarships.

The Great Lakes Foundation Grant supports projects aimed at preserving wilderness areas and promoting marine safety in the Great Lakes region. As a 501(c)(3) charitable organization, the foundation has awarded over $318,212 since its inception in 1993. Grants have funded various initiatives, including breakwater construction and academic research, to enhance appreciation and safety of the marine environment for both members and the general public.

The Jane Eleanor Knox Scholarship, established by a $50,000 bequest from Dr. Knox, supports doctoral nursing students committed to leadership in the field. Applicants must possess a current RN license and maintain a minimum GPA of 3.6 while enrolled in accredited nursing programs. Preference is given to those focusing on nursing research or organizational studies. This scholarship fosters the advancement of nursing education and leadership through financial support from Nurses Educational Funds, Inc.

Interface Health Foundation

Interface Health Foundation is a non-profit, 501c3 tax-exempt organization driven by a collective vision of positive change. In healthcare industry policy, understanding the intricate dynamics of funding and its impact on public access, quality, and cost remains paramount. IHF is dedicated to advancing analysis and research into the crossroads of healthcare industry policy, structural frameworks and affordability.

At IHF, our mission is clear: to empower and support student-led research endeavors that shed light on critical healthcare policy and structural issues affecting the public. Through our initiatives, we seek to foster a deeper understanding of the complex dynamics shaping the healthcare landscape.

Interface Health Foundation: Research Grant

Healthcare administrative grant award opportunities are highly competitive and allow candidates to stand out as they enter the job market. Through this IHF grant award, you will get the opportunity to pull together research and content on topics that aren't fully studied or publicized. Depending on the grant topic, some grantees will also have access to a preceptor who is an executive leader in the healthcare field. The preceptor will serve as a valuable resource to the grantee during the development of the research paper and beyond.

An example of a research topic is the impact of legislated acute care nurse staffing levels on the following: nursing professional job satisfaction, the patient experience, and the standard nursing quality indicators as part of nursing Magnet status accreditation.

The FY 2026 funding opportunity aims to support Indian Tribes and intertribal consortia in implementing approved Nonpoint Source management programs under the Clean Water Act Section 319. This initiative, funded by the EPA, focuses on addressing NPS pollution through best management practices as outlined in Tribal NPS Management Program Plans, ensuring the protection of water resources and promoting sustainability in Tribal lands.

The John E. Mayfield ABLE Scholarship Fund supports graduating seniors who are participants in the ABLE program, enabling children with disabilities to excel in post-secondary education. Established by John Mayfield, this scholarship encourages individuals to pursue their educational dreams, fostering independence and productivity within the community. The Community Foundation of Middle Tennessee, with over 30 years of philanthropic experience, administers the fund to ensure resources are directed where they can make the greatest impact.

The AAAAI Foundation Faculty Development Award provides $300,000 in funding over three years to support the growth of junior faculty in the fields of allergy and immunology. This initiative, spearheaded by the American Academy of Allergy, Asthma & Immunology, aims to foster the development of future leaders and independent researchers dedicated to combating asthma and allergic diseases through impactful research.

The Chrysalis Project Program, hosted by the American Academy of Allergy, Asthma & Immunology (AAAAI), offers an exciting opportunity for U.S. and Canadian medical students and residents to explore the field of allergy and immunology. Participants can attend the AAAAI Annual Meeting free of charge, enhancing their understanding and interest in this vital subspecialty. This initiative aims to cultivate the next generation of allergists, fostering professional growth and engagement in allergy and immunology.

The TTF Advertising for the Environment Grant, established by the Temper of The Times Foundation in 1997, aims to enhance awareness of wildland conservation through marketing initiatives. This grant is exclusively available to 501(c)(3) nonprofit organizations and funds various advertising campaigns to protect native ecosystems. Priority is given to projects that demonstrate measurable impacts on conservation, rather than those focused solely on education.

American Headache Society

The American Headache Society (AHS) is a professional society of healthcare providers dedicated to the study and treatment of headache and face pain. The Mission of the AHS is to improve the lives of people impacted by migraine and other headache disorders. AHS advocates for those impacted by headache and the headache field, to meet our core objectives. AHS provides educational courses, scientific meetings, a journal, research support, career development opportunities, Special Interest Groups, advocacy training, and a professional community. The AHS strives to meet its objectives while fostering an inclusive sense of belonging and community.

Headache & Migraine Competitive Grant Program

The Headache & Migraine Competitive Grant Program stands at the forefront of advancing headache medicine by funding groundbreaking quality improvement initiatives. This highly competitive grant program, offered through the collaboration between the American Headache Society and Pfizer, supports projects that have the potential to reshape the field by creating widely applicable tools and driving measurable improvements in patient care. 

Migraine & Women's Health

Migraine is a prevalent and debilitating neurological disease that disproportionately affects women, impacting quality of life, productivity, and overall health. Recognizing the need for innovative solutions and enhanced care, Pfizer and the American Headache Society (AHS) are collaborating to offer a new grant opportunity inviting proposals for collaborative quality improvement and research projects focused on migraine and women's health.

The George Family Foundation's Youth Development Grant aims to empower youth from under-resourced communities by supporting initiatives that foster personal growth, educational enrichment, and workplace learning. By encouraging diverse interactions and community service, the foundation seeks to provide young people with the tools to thrive and positively impact their communities. Although unsolicited proposals are not accepted, Letters of Inquiry are welcomed during specific review periods.

The Lois Lenski Covey Foundation offers the Bookmobile Grant to promote literacy among underserved children. Grants range from $500 to $3,000 specifically for purchasing books for youth from preschool to grade 8. Eligible organizations include 501(c)(3) nonprofits and public libraries that operate lending bookmobiles. The Foundation aims to ensure access to quality literature, fostering a love of reading in disadvantaged communities while addressing their limited book budgets.

The Westminster Presbyterian Church Scholarship aims to address contemporary community needs by providing financial support for education and job training. This initiative, led by the Community Foundation of Elmira-Corning and the Finger Lakes, emphasizes a holistic approach to community welfare, including arts, infrastructure, and wellness. It is designed for individuals who are currently employed full-time and seeking further education or job training opportunities.

The AJN/Thelma Schorr Scholarship, offered by Nurses Educational Funds Inc., supports professional nurses pursuing master's or doctoral degrees. Applicants must have at least two semesters remaining after the award notification and hold a current RN license. The scholarship aims to foster nursing leadership, particularly for those advocating for the profession through various platforms. Established in memory of Thelma Schorr, it recognizes candidates demonstrating leadership qualities in nursing.

Tree and Soil Research Fund for Landscape Architecture Grant Program

The TREE Fund Board of Trustees is launching the new Tree and Soil Research Grant, made possible by a permanently restricted endowment fund supporting areas of research of interest to the landscape architecture community with special focus in the area of trees and the soils that support them. Projects are expected to be completed within one to three years, with a maximum award value of $10,000. No project may receive more than one award from this program. 

Award amount:

• up to $10,000 (minimum $5,000) 

The Maternal, Infant, and Early Childhood Home Visiting Program (MIECHV) aims to enhance maternal and child health, promote early childhood development, and support family well-being. By providing voluntary, evidence-based home visiting services to pregnant women and families with young children, the program addresses critical needs in communities. Funded by the US HHS: Health Resources & Services Administration (HRSA), MIECHV empowers families through tailored support and resources, fostering healthier outcomes for mothers and their children.

The Lawrence F. and Barbara J. Dickman Scholarship supports Zeeland High School graduates pursuing higher education in the U.S. on a medical track. Applicants must demonstrate financial need and can reapply if they have received the award previously. Recommendations from teachers or counselors are required. Scholarships are usable starting in the fall of the announcement year and unaccepted scholarships will be forfeited after December 31. This scholarship aims to foster future healthcare professionals.

The CAFE Group 

We resource leaders, invest in their genius, and bring people together to reimagine what philanthropy can do.

Founded by Liz and Don Thompson, The CAFE Group is a national nonprofit transforming how change is resourced. 

With a focus on education equity, social capital, and philanthropic transformation, we pair catalytic funding, community-rooted leadership development, and cross-sector collaboration to strengthen the people and institutions shaping a more just future. Everything we do is grounded in relationship, because we believe the way resources move matters just as much as where they land.

The 1954 Project Luminary Award

The 1954 Project Luminary Award celebrates transformational education nonprofit leaders dedicated to serving Black students and communities through powerful investments in their organizations' ability to create lasting change.

The Luminary Experience

Each Luminary organization gets more than funding. Through The 1954 Project, leaders gain a community, a platform, and space to grow with tailored support over the course of the three year journey.​

• $1 Million, Unrestricted: Catalytic funding to expand what’s working.
• Leadership Coaching + Capacity Support: Guidance from peers and experts who are committed to helping you build a lasting, impactful organization.
• National Network: Luminaries join a powerful community of innovators, change-makers, and visionaries driving systemic progress to support students and communities across the U.S.

The 1954 Project’s Impact Areas

We focus on three interconnected areas critical to advancing equity:

• Innovation in Teaching and Learning: Create education models that center Black students through culturally affirming approaches that challenge traditional structures and transform how learning happens, ultimately serving all students. 
• Diversity in Education: Build pathways that increase and sustain Black educators and education leaders who transform where and how students learn.
• Pathways to Economic Mobility: Build pathways to wealth, ownership, and economic power for Black students, families, and communities through innovative educational programming.

Our Selection Criteria

We seek out extraordinary applicants who embody our values and vision across three categories:

Leader: We look for leaders whose influence and vision contribute to the collective well-being and advancement of the Black community. These leaders:

• Are Visionary: They demonstrate a strategic and pragmatic mindset, articulating a transformative vision for significant, positive change.
• Show Demonstrated Commitment: They embody steadfast dedication to your cause, inspiring and influencing others, and galvanizing community involvement.
• Are Adaptive: They assertively tackle challenges, turning setbacks into opportunities for innovation, while maintaining humility and thoughtfulness in problem-solving.

Organization: We look for organizations that drive significant change, anchored by a deep love for people and driven by the genius within communities of color. These organizations: 

• Have a Defined Problem: They clearly identify the issue they are addressing and explain in detail how your organization tackles root causes. 
• Take a Strategic Approach: They have clear, measurable, and achievable organizational goals with a well-defined strategy informed by thorough analysis. 
• Show Demonstrated Impact: They have a tested model that has produced positive results, incorporating continuous learning and iteration. 
• Have a Transformation Plan: They present a clear plan for using the $1M award to advance your organization's mission, vision, and long-term goals. 
• Embrace Collaboration: They use collaborate to build partnerships based on trust, love, and common goals. 

Radical Imagination: We seek leaders who challenge and redesign societal norms to build a just and equitable future. They demonstrate:

• Community-Rooted Leadership: They maintain and cultivate genuine community ties, integrating professional expertise and personal commitment to drive visionary, impactful strategies. 
• Long-Term Commitment: They are in it for the long haul, committing to sustained impact across generations and prioritizing long-lasting solutions over short-term gains. 
• Collectivism: They embody the philosophy of "I am because we are," actively engaging in collaborative networks and fostering community-reflective solutions. 

The Sex Worker Giving Circle Grant, launched by the Third Wave Fund, prioritizes funding for grassroots movements led by individuals directly impacted by gender oppression, especially within the sex work community. With a commitment to gender justice, the grant supports organizations that operate with a participatory approach to grantmaking, enabling them to address systemic inequalities. In recent years, the fund has distributed significant resources to empower and sustain these vital movements across the United States.

Spencer Educational Foundation Inc

The Spencer Educational Foundation was founded by the Rims Atlanta Chapter in 1979. To this day, Spencer remains the premier organization funding the education of tomorrow's risk management and insurance leaders.

The Spencer Educational Foundation: awards merit-based scholarships and grants to university students pursuing careers in risk management, insurance, and/or actuarial science; provides grants that create experiential learning opportunities both on and off campus; funds the development of risk management and insurance curricula in colleges and universities; supports Risk Managers by creating internship opportunities within the risk management function of their companies; and operates across the United States and Canada. 

Spencer Educational Foundation: General Grants

Spencer’s goal to help build a talent pipeline of Risk Management and Insurance professionals is achieved in part by our collaboration with Risk Management and Insurance educators across the United States and Canada. Since 2010, Spencer has awarded over $4.5 million in General Grants to support over 225 student-centered experiential learning initiatives at universities and RMI non-profit orgs.

Spencer's General Grants Program supports student-centered initiatives that (1) provide experiential learning opportunities for Risk Management & Insurance students and (2) attract new talent to risk and insurance careers. 

The Guy P. Gannett Journalism Scholarship supports aspiring journalists through financial assistance based on need and academic merit. Students are selected for their commitment to journalism, demonstrated through coursework and activities. This scholarship, which ranges from $1,000 to $60,000, is renewable for students pursuing journalism or related fields, provided they are graduates from Maine high schools or homeschooled in Maine. Recipients are encouraged to show continued dedication to their journalism careers.

The Bill and Cay Harris Scholarship, established in 2010, supports graduating seniors from Ashland County high schools who demonstrate Christian service and leadership qualities. Funded by the Ashland County Community Foundation, this scholarship aims to assist students with a minimum GPA of 2.5 who are accepted to accredited colleges or universities. Preference is given to those majoring in History or Social Studies. Bill and Cay Harris, notable community figures, inspire future generations through this scholarship.

The Twin Valley-Gary Area Community Fund and Joseph Urdahl Memorial Fund, managed by the Northwest Minnesota Foundation, aims to enhance the quality of life for residents and visitors in the Twin Valley-Gary area. This year, there is a specific preference for projects supporting Health & Wellness initiatives. Eligible projects should focus on charitable, educational, and public-purpose efforts, benefiting the local community, which includes several townships under the Norman County East School District.

The Multiple Sclerosis Clinical Care Physician Fellowship: Pediatric Care, offered by the National Multiple Sclerosis Society, aims to enhance the training of physicians in providing specialized care for pediatric patients with MS. This one-year post-residency program emphasizes direct patient care and multidisciplinary collaboration. Participants will learn under the supervision of MS specialists, gaining essential skills to improve clinical practices and contribute to the MS community, ultimately leading to better outcomes for those affected by this condition.

The Ashland County 4-H Committee Scholarship supports graduating seniors involved in the Ashland County 4-H Program. Funded by Dean and Marge McBurney, this scholarship recognizes students based on their 4-H participation, extracurricular activities, and financial need. It aims to assist students in pursuing higher education, ensuring that they have the resources and encouragement needed to achieve their academic goals.

The Altrusa Club of Ashland Scholarship, established in the late 1950s, supports Ashland County students, particularly non-traditional women returning to education. Awarded annually, it targets graduating seniors with a GPA of 2.5 to 3.0 accepted into accredited colleges. Funded by the Ashland County Community Foundation, this scholarship aims to enhance educational opportunities and empower individuals to contribute positively to the workforce and community.

The Sidney R. Baer, Jr. Foundation offers Clinical Research Grants to support advancements in the treatment and understanding of schizophrenia and bipolar disorder. Focused on organizations with IRS tax-exempt status, these grants aim to enhance mental health services and research. By funding initiatives in cognitive and behavioral sciences, the foundation seeks to improve the lives of those affected by serious mental illness, ensuring they receive the support and resources necessary for a better quality of life.