Best Grants for New Nonprofits in Mississippi

The National Institute of Allergy and Infectious Diseases (NIAID) is calling for applications for four Leadership and Operations Centers (LOCs) as part of its HIV/AIDS Clinical Trials Network initiative. These LOCs will guide research on HIV therapeutics, prevention, and treatment strategies across diverse populations. The initiative aims to enhance evidence-based practices and improve health outcomes for individuals affected by HIV, ultimately contributing to the goal of ending the HIV epidemic.

The National Institute of Allergy and Infectious Diseases (NIAID) is launching a funding opportunity for up to four Clinical Trials Network Laboratory Centers (LCs). These LCs will support HIV prevention and treatment strategies by providing necessary laboratory infrastructure and technologies for clinical trials. They will ensure rigorous laboratory testing and oversight, enhance sample integrity, and utilize advanced data management systems to meet evolving demands in HIV research and testing.

Community Foundation of East Mississippi

With over 40 years of dedicated service, the Community Foundation of East Mississippi (CFEM) is committed to fostering charitable giving that connects generous individuals, families, and businesses to meaningful causes.

Mission: A catalyst for charitable giving where civic-minded individuals, families, and businesses achieve philanthropic goals. We bridge resources and needs to enhance the dynamic communities we serve.

Grant Opportunities

Community Foundation of East Mississippi awards grants through several competitive application processes each year.

Our service area includes the following 5 counties in East Mississippi: Clarke, Kemper, Lauderdale, Neshoba and Newton. 

To receive a grant from the Community Foundation of East Mississippi, all organizations must have the following information readily available. The Foundation may request these documents at any time during the application process and/or after receiving funds.

• Internal Revenue Service 501(c)(3) tax exemption letter OR fiscal sponsorship agreement
• Charitable registration letter from the Mississippi’s Secretary of State’s Public Charities Section, or a current letter stating that your organization is exempt from registration
• Vision, Values, and Mission Statement
• Audited Financial Statements (Form 990)
• Staff Listing
• Board of Directors Roster

Lean on Me Suicide Awareness and Support Grant

The 2025 Lean on Me Jubilee event team are proud of the success of the Second Annual Lean on Me Jubilee, held September 27th, 2025. The event was a great time to connect with the community and each other to move the mission of Suicide Awareness, Prevention, and Support forward.

We are pleased to announce that the funds raised at the event will be returned to community partners through mini grants to support other non-profit organizations whose mission aligns with the mission of the Lean on Me Jubilee event team. All community non-profit organizations with programs for Suicide Awareness, Suicide Prevention, or Support for families affected by suicide are welcome to apply, but preference will be given to those who participated in making the Lean on Me Jubilee event a success.

The National Institute of Allergy and Infectious Diseases (NIAID) is launching a funding opportunity for Clinical Trials Units (CTUs) as part of its effort to combat HIV/AIDS. This initiative aims to support innovative clinical trials and implementation research to improve prevention and treatment strategies. With a focus on both domestic and international research sites, CTUs will play a crucial role in addressing the HIV epidemic and enhancing participant recruitment and retention. This funding opportunity is authorized under the Public Health Service Act.

Jack Kent Cooke Foundation

The Jack Kent Cooke Foundation is dedicated to advancing the education of exceptionally promising students who have financial need. Since 2000, the Foundation has awarded $304 million in scholarships to more than 3,400 students from 8th grade through graduate school, along with comprehensive academic advising, career pathway counseling and other support services. The Foundation has also provided $136 million in grants to organizations that serve such students.

The Jack Kent Cooke Foundation’s scholarship programs are designed to encourage and support outstanding students who work hard and have financial need. Our scholarships provide financial assistance and academic support to high school, undergraduate, and graduate students. In addition to the monetary award, students join a thriving network of more than 3,400 Cooke Scholars.

Young Scholars Program

The Cooke Young Scholars Program is a selective five-year, pre-college scholarship for exceptionally promising 7th grade students with financial need. It provides comprehensive academic and college advising, as well as financial support for school, Cooke-sponsored summer programs, internships, and other learning enrichment opportunities.

Program Experience

Educational Advisers support Young Scholars to maximize high school experiences and to go on to thrive at the nation’s top-performing colleges. Our programming and support may include:

• Identifying an appropriately rigorous high school.
• Engaging in four-year planning and goal-setting.
• Funding for academic and extracurricular opportunities, such as music and art lessons, supplemental academic classes and technology.
• Annual summer programs, including two required Young Scholar programs.
• Year-round Young Scholars community programming.
• Networking opportunities with a high-achieving peer community.

The Alice M. Ditson Fund offers organizational support for summer festivals and conferences focused on contemporary American classical music. This funding opportunity encourages the appreciation of works by younger, relatively unknown American composers. Eligible applicants include performing organizations and institutions that promote artistic excellence. The Fund emphasizes supporting living composers at various career stages, ensuring a broader recognition of their contributions to classical concert music. It is crucial for applicants to align their projects with the Fund's mission of enhancing public knowledge and appreciation.

About

With deep roots in California’s Central Valley, The Save Mart Companies and its family of stores prides itself in being a part of neighborhoods and putting people first. Our dedication to customers is reflected in the connections we’ve made in the communities we’ve served for more than 70 years.

The Save Mart Companies CARES Foundation

In 2000, we established The Save Mart Companies CARES Foundation, our philanthropic, non-profit organization, supporting programs and organizations that provide vital resources for children and families in the communities we serve. The CARES Foundation focuses on building stronger communities through fresh foods, accessibility, and programs that support youth and helping them to thrive. Annually, The CARES Foundation contributes approximately $500,000 in small grants to support community-based, non-profit organizations.

The Save Mart Companies CARES Foundation Grant

The CARES Foundation’s focus is building stronger communities through fresh foods, access to food, and programs that support youth and helping them thrive.

The CARES Foundation will review, on a quarterly basis, among other things, the breadth of the audience served; the likely impact in the community; the importance of the need to be addressed in the community; and the community reputation, service history, and financial stability of the group or program seeking funds. No one of these or other factors will necessarily be weighted more heavily than another. Instead, each group or program will be measured against all groups and 2 programs seeking funding at the time. For example, a program serving a small segment of the community but that addresses an especially important community need, and thus has the potential for a strong and meaningful impact, would be favored over a group serving a wider clientele but that fills a less important community need. Requests for Grants should be a minimum of $500.00 up to $10,000.00. Programs and organizations requesting smaller grants should contact the Store Manager of the nearest Save Mart Companies’ store location for request consideration.

Recipients that receive grants for more than one year must demonstrate meaningful outcomes for the previous investment made by The CARES Foundation.

The Ochylski Family Foundation supports registered 501(c)(3) nonprofit organizations through grants aimed at enhancing their operational capacity. With an application deadline of October 1, organizations must submit a detailed request outlining their initiatives. The foundation's mission aligns with its commitment to foster community development and nonprofit effectiveness in Iowa, ensuring that resources are allocated to impactful projects that serve the public good.

The Store-Based Giving Program by Ross Stores Foundation supports socioeconomically disadvantaged youth by providing gift cards for school or professional clothing. Organizations must be federal tax-exempt and serve at least 60% low-income youth. Eligible programs include academic achievement and life skills initiatives. Award amounts typically range from $300 to $500, depending on budget and mission alignment. Applications are not accepted from organizations that have received donations within the past 12 months.

The Delaney L. Wykle Nursing Scholarship, managed by the Beckley Area Foundation, aims to support nursing students from Raleigh and Summers counties in West Virginia. Applicants must demonstrate financial need, possess a minimum 3.0 GPA, and be enrolled in an accredited four-year nursing program. This scholarship helps empower students to achieve their educational goals while enhancing community health services in Southern West Virginia.

The MRFBC Young Investigator Team Award supports innovative research in immuno-oncology for melanoma, offering up to $150,000 annually for two years. This funding targets U.S.-based researchers aiming to enhance clinical outcomes for melanoma patients or deepen the scientific understanding of immuno-oncology. The MRF collaborates with key institutions to address challenges in melanoma research, fostering partnerships that maximize research potential and impact.

The Melanoma Established Investigator Award offers up to $125,000 annually for two years, aimed at established melanoma researchers or senior researchers transitioning into melanoma research. Eligible applicants include Associate Professors or higher, with both tenured and non-tenured faculty encouraged to apply. U.S. citizenship is not a requirement for this funding opportunity provided by the Melanoma Research Foundation.

The Melanoma Career Development Award (CDA) is offered by the Melanoma Research Foundation to support researchers dedicated to melanoma and its prevention. This award is designed for postdoctoral fellows with under five years of experience, research associates, scientists, staff scientists, assistant professors, and those focusing on melanoma prevention. The initiative promotes innovative research to advance understanding and treatment of melanoma, ultimately aiming to reduce its impact.

The 1954 Project - Luminary Award seeks visionary nonprofit leaders dedicated to advancing educational equity for Black students. Awardees receive $1 million in funding, leadership development, and networking opportunities. The selection prioritizes leaders demonstrating strategic vision, community commitment, adaptability, and collaborative spirit. Applicants must align with one of three impact areas: Innovation in Teaching and Learning, Diversity in Education, or Pathways to Economic Mobility, ensuring their initiatives foster systemic change and uplift marginalized communities.

A funding opportunity designed to support food security, refugee services, licensed free healthcare clinics and community development organizations in the United States.

Turkey Distribution 2026

IRUSA facilitates annual Turkey Distributions in cities across the United States during Thanksgiving. IRUSA will procure and deliver turkeys to partners that will deliver them onto people in need. Along with turkeys, partner organizations may distribute other Thanksgiving goods to assist individuals and families who may not have access to these food items. The distribution may occur with regular food pantry distribution dates or as its own event. The goal of this event is to not only address food insecurity in local communities but to also embody the season of giving by bringing the holiday festivities to those who would otherwise not be able to enjoy a Thanksgiving meal in their homes.

The Anne and Tony Hillerman Scholarship, part of the New Mexico Press Women Scholarship Fund, supports New Mexico students pursuing undergraduate or graduate degrees in journalism or communications. Established in 2023, the fund promotes ethical journalism and offers networking opportunities through the NMPW Annual Conference. Eligible applicants must be enrolled in a relevant program, provide a portfolio of work, and submit a personal essay detailing their interests and career goals. This scholarship fosters the next generation of communicators and advocates for First Amendment rights.

A funding opportunity designed to support food security, refugee services, licensed free healthcare clinics and community development organizations in the United States.

Summer Food Service Program (SUN) program 2026

The Summer Food Service Program (SUN), created and funded by the United States Department of Agriculture (USDA), currently provides organizations with limited funding opportunities to purchase and provide meals to their local communities in the form of reimbursements. Starting in 2011, IRUSA began to supplement and support the USDA in this effort. SUN recipient, organizations are able to start a USDA-approved site, increase the capacity of their current USDA-approved site(s) or develop their role as the meal-providing sponsor to subgrantees. Grants are provided to further enable and encourage wider participation in this program as well as increase food access and support to food-insecure children throughout the summer months. 

The Encompass Health Therapy Grant offers up to $50,000 for research on the effectiveness of therapies in inpatient rehabilitation facilities. This funding aims to enhance understanding of neurological impairments and improve patient outcomes through evidence-based practices. Eligible projects must be conducted in the U.S. or Puerto Rico, require a defined research protocol, and adhere to ethical standards. The grant prioritizes studies on therapy impact, implementation science, and caregiver education, contributing to the advancement of rehabilitation care.

The Kiwanis Club of Albuquerque Scholarship Fund, established in 1948, supports graduating seniors from Albuquerque metro area high schools who demonstrate strong academic performance and community service. Annually, one to four scholarships of up to $1,000 are awarded to students pursuing careers in child development and teaching. The fund emphasizes the importance of community involvement and academic excellence, encouraging students to share their career goals and financial needs through an essay as part of their application.

The New Mexico Veterans Memorial Scholarship, established in 2024, supports graduating high school seniors in New Mexico who embody the Medal of Honor Core Values: Courage, Sacrifice, Integrity, Commitment, Patriotism, and Citizenship. This scholarship encourages students to explore and reflect on these values through a personal essay and community service. Preference is given to students from Albuquerque High Schools, fostering a commitment to excellence and civic duty among the youth.

The Little Giraffe Foundation is dedicated to supporting neonatal health through research grants ranging from $5,000 to $10,000. Since 2011, they have provided substantial resources to hospitals and institutions, focusing on both immediate and long-term health challenges faced by premature infants. Eligible applicants include scientists and healthcare professionals from U.S.-based institutions. The foundation aims to advance research in biological processes, genetics, clinical studies, and more, improving outcomes for vulnerable populations.

The Little Giraffe Foundation, a national non-profit based in Chicago, provides NICU Support Grants ranging from $100 to $1,000. Since 2011, they have positively impacted countless families by delivering over 32,000 gift bags and funding essential research. These grants aim to enhance the experience for parents and patients in neonatal intensive care units, supporting initiatives like holiday gift bags and resources for bonding with babies. Applications are welcomed from eligible U.S.-based institutions.

The NIHCM Foundation's Local Media Award honors outstanding local journalism that enhances understanding of health care issues in the U.S. It aims to recognize reports that improve health care affordability, accessibility, and quality. A $15,000 prize is awarded to the winner. Eligible entries must be published in 2025 and focus on local markets, offering insights relevant to health plans and policymakers. This award encourages innovative reporting that addresses the complexities of the health care system.

The ASTRO-LUNGevity Residents/Fellows in Radiation Oncology Seed Grant aims to enhance the research careers of residents and fellows focused on radiation oncology, specifically benefiting lung cancer patients. This initiative supports basic, translational, and clinical research endeavors. With a maximum award amount of $50,000 for one year, it provides essential funding to foster innovative projects that can lead to significant advancements in lung cancer treatment.

The Elizabeth M. Keithley, Ph.D. Early Stage Investigator Awards (EMKESIA) offers funding of up to $50,000 per year for early-stage researchers focused on hearing and balance research. Managed by the Hearing Health Foundation, the program encourages innovative projects and supports the next generation of scientists. Eligible applicants must hold relevant degrees and demonstrate a pathway to independence in their research careers, contributing to advancements in hearing health solutions.

This funding opportunity invites renewal applications for existing NINDS-supported clinical trial cooperative agreements (U01) that require additional time and resources. The National Institute of Neurological Disorders and Stroke (NINDS) expects applicants to request only what is necessary for trial completion, without introducing new aims. Discussions with NINDS prior to submission are encouraged. Eligible applications must be renewals of previously approved cooperative agreements under specified NIH funding announcements.

Innovations in Low-Cost and Simplified Pathogen Sequencing Workflows

Catalyzing Innovation through Partnerships

At its core, Grand Challenges catalyzes bold innovation through partnership - bringing together funders, researchers, implementers, and public health leaders to solve complex global challenges. This multi-partner initiative reflects the Grand Challenges ethos, leveraging complementary expertise and investments to accelerate accessible genomic sequencing solutions for low- and middle-income Countries.

About this Challenge

This Grand Challenge is co-funded by the Gates Foundation, and the Temasek Foundation, and will be managed by the United Nations Foundation. This Grand Challenge is implemented in collaboration with a network of global and regional partners, including International Pathogen Surveillance Network (IPSN), hosted by the WHO Hub for Pandemic and Epidemic Intelligence, the Africa Pathogen Genomics Initiative (Africa PGI), and the Asia Pathogen Genomics Initiative (Asia PGI) as regional technical and public-health partners. This RFP aims to accelerate the development of affordable, scalable, and operationally simple sequencing solutions, enabling routine use of genomics for public health in low- and middle-income countries (LMICs).

Award Structure and Funding Level

To accommodate different stages of innovation maturity, this RFP supports a tiered award structure, with funding levels and expectations aligned to the readiness and scope of the proposed work. Indicative award categories are:

For concepts with preliminary feasibility evidence that are ready to advance from prototype toward an integrated workflow—optimizing performance, broadening assay or pathogen coverage, and generating more robust cost-reduction and performance data.