Best Small Grants for Nonprofits in Mississippi

The Alcon Foundation Grant aims to enhance eye care services and improve patient access, with a focus on educational and training programs. The foundation also supports cultural and community development initiatives that uplift the quality of life in areas where Alcon operates, including cities like Fort Worth, Houston, and Irvine. However, it does not fund non-501(c)(3) organizations, athletic leagues, or fundraising events, among other exclusions.

The DoW Peer Reviewed Cancer Clinical Trial Award supports the rapid initiation of clinical trials aimed at significantly improving cancer treatment. Projects may range from small pilot studies to large-scale phase III trials, focusing on innovative products, drugs, or devices. This award mandates the inclusion of patient advocates and prohibits animal studies, ensuring that all preclinical work is completed prior to the award start date. Regulatory applications must be submitted if required for the proposed trials.

The FY26 Peer Reviewed Cancer Research Program Impact Award promotes significant research aimed at enhancing clinical cancer care. It requires preliminary data to ensure feasibility and emphasizes projects with a strong potential for immediate impact. This funding supports clinical trials and allows for either a single Principal Investigator or a duo of partnering PIs, ensuring that both can contribute distinct aspects of the research. Applications must be carefully coordinated to avoid withdrawal risks.

The FY26 Traumatic Brain Injury and Psychological Health Research Program's Clinical Trial Award aims to fund impactful clinical trials that address psychological health issues and traumatic brain injury (TBI). This award supports a variety of interventions, requires preliminary data, and mandates community-based participatory research approaches. It offers two research levels: one for pilot studies and early trials, and another for larger, advanced trials assessing effectiveness in relevant populations.

The Craig H. Neilsen Foundation's Creating Opportunity & Independence Grant supports programs and research that enhance the quality of life for individuals with spinal cord injuries (SCI). It welcomes applications from nonprofit organizations and rehabilitation facilities in the U.S. and Canada, focusing on projects that foster independence, community participation, and capacity-building. Priority is given to initiatives that demonstrate broad impact and involve individuals with SCI, ensuring their needs and perspectives shape the proposed activities.

The Reeves Foundation supports research aimed at understanding and treating macular degeneration, a condition that has personally affected the founder's family. Established in 1997, the foundation allocates 50% of its grants to research and the other half to local charities in Columbus, Indiana. Nonprofit organizations exempt under IRS code 501(c)(3) are eligible to apply, but funds cannot be used for administrative costs. The foundation prioritizes equipment purchases and partnerships with other funding sources.

The Visionary Prize for Women’s Economic Empowerment, established in 2022 by Visionary Women and the Hostetler/Wrigley Foundation, honors a visionary woman leader of a nonprofit focused on advancing women's economic empowerment in the U.S. This prestigious award provides $100,000 in unrestricted funds to support the recipient's agency and its initiatives. Eligible candidates must have a minimum of four years of operation and an annual budget exceeding $500,000, actively working towards women's economic advancement.

Community Foundation of Central Wisconsin

The Community Foundation of Central Wisconsin gives everyone the opportunity to make significant and lasting gifts to their community. We manage over 320 funds that enhance Portage and Waushara counties. Together with our generous donors, we create a strong culture of philanthropy in Central Wisconsin.

We are a tax-exempt, 501(c)(3) public charity founded in 1982 to provide scholarships and grants to organizations and projects that improve the quality of life in Portage and Waushara counties.

Scholarships

The Community Foundation proudly supports students in Portage and Waushara counties with over $325,000 in scholarships annually, thanks to the generosity of local individuals and families. Award amounts range from $500 to $40,000, opening doors to educational opportunities.

Whether you're a student seeking financial support or a donor looking to grow a scholarship fund, we invite you to explore available opportunities and learn how you can be involved.

Don & Mary Hamerski Memorial Scholarship Fund

Qualifications: Graduating High School seniors from a Central Wisconsin high school.

The FY26 Traumatic Brain Injury and Psychological Health Research Program (TBIPHRP) aims to support impactful health services research that connects research, practice, and policy. It emphasizes building real-world evidence for interventions and clinical guidelines tailored to specific populations. Key features include requirements for clinical trials, preliminary data, and community-based participatory research approaches. The program also offers an Early-Career Investigator Partnering Option to foster collaboration between seasoned and emerging researchers.

The NCI Research Specialist Award (R50) supports clinician scientists involved in NCI-funded clinical trials. This funding opportunity encourages the development of stable research careers by providing salary support and autonomy, allowing clinician scientists to contribute to national clinical trial development and implementation. They play a critical role in sustaining the NCI clinical trials network without serving as principal investigators. This award aims to ensure continuity in cancer research careers.

The NCI Research Specialist Award (R50) supports non-tenure track scientists in cancer research who provide essential contributions within laboratories and core facilities. This award aims to enhance research careers for skilled scientists who do not seek independent investigator funding. Eligible candidates must possess an advanced degree, have at least two years of contribution to NCI-funded research, and dedicate a significant portion of their time to this work. The R50 offers salary support and travel funds to recognize and stabilize these vital roles in cancer research.

The DoW Traumatic Brain Injury and Psychological Health Translational Research Award aims to transform scientific discoveries into clinical applications. This program encourages innovative research approaches and requires preliminary data. It prohibits basic research and clinical trials, emphasizing the need for relevant animal models or community-based participatory research for human subjects. Funding supports two research levels, refining ideas into tangible products or evaluating them for clinical trials, with options for early-career investigator partnerships.

Extreme Terrain’s Clean Trail Initiative Program aims to enhance trail integrity by supporting groups in the U.S. with grants for projects like trail clean-up, restoration, and expansion. Eligible applicants include Wrangler and 4x4 clubs, environmental organizations, and those managing public or private trails. The initiative emphasizes responsible off-roading while encouraging volunteers to engage in improving our natural landscapes. This program fosters community involvement and promotes sustainable practices in outdoor activities.

The Jordan Fund, established by John & Kelly Olerud in 2003, is dedicated to supporting children with special needs and their families. This grant-making organization assists children with substantial disabilities up to age twenty-one, covering costs for respite, therapy, and essential equipment not provided by insurance. By funding 501(c)(3) organizations, the Jordan Fund aims to enhance the quality of life for these children and their families.

The Family-to-Family Health Information Centers (F2F HIC) program, funded by the US HHS: Health Resources & Services Administration (HRSA), aims to empower families of children and youth with special health care needs (CYSHCN). By providing crucial information, education, and peer support, the program helps families navigate complex health systems to access necessary services, ultimately enhancing the health and well-being of CYSHCN and their families.

Marion Community Foundation

Since 1998, area residents have been turning to Marion Community Foundation to make their philanthropic giving as effective as possible. We are a public charity serving thousands of people who share a common concern … improving the quality of life in Marion County. We use distributions from the more than 500 charitable funds — created by generous, local donors — to award more than $2.5 million in grants and scholarships each year to many of the humanitarian, educational and cultural organizations in this remarkable community we call home.

Marion Community Foundation is the area’s leading philanthropic organization, providing charitable donors the opportunity to easily create endowment funds to benefit and support our community through grants and scholarships. We serve communities throughout Marion County through philanthropy, leadership, and civic engagement.

Clare Cooke Performing Arts Scholarship

Clare Cooke, the namesake of this fund, has worked as a performer, choreographer, and director for the Marion Palace Theatre since 1977, directing Christmas at the Palace and numerous community theater productions and junior musicals for many years, including The Wizard of Oz, The Will Rogers Follies, Annie, Oliver!, The Music Man, Guys and Dolls, Hairspray, and Oklahoma!

The Clare Cooke Performing Arts Scholarship Fund, created in 2012 through gifts from nearly 100 friends and family members, recognizes her outstanding contributions to the performing arts community and quality of life in Marion.

The Cooke Fund awards scholarships to Marion County high school seniors and graduates pursuing an education in the performing arts. Recipients are high school seniors who rank in the top 50th percentile of their graduating class or graduates with a college GPA of at least 2.5.

The NIH Blueprint Initiative aims to enhance neuroscience research by funding the development and application of germline and somatic gene-editing techniques. This initiative builds on existing marmoset gene-editing frameworks and integrates New Approach Methodologies (NAMs) to improve understanding of human brain function and disease. High-priority areas include complex conditions like autism and schizophrenia. The initiative emphasizes the use of appropriate models to address critical questions in neuroanatomy, cognition, and behavior related to human brain health.

The CATCH Grant, offered by USA Football, provides essential support to organizations facing critical challenges such as natural disasters or theft. This program aims to enhance the athlete experience by assisting with unexpected hardships affecting operations. Eligible organizations enrolled with USA Football can apply for varying award amounts based on their specific circumstances. For more information, refer to the FAQs available on the USA Football website.

The FY26 Spinal Cord Injury Research Program (SCIRP) Investigator-Initiated Research Award (IIRA) supports innovative research aimed at enhancing patient care and quality of life for individuals with spinal cord injuries. This award encourages collaboration, allowing an Early-Career Partnership Option for two Principal Investigators, where one must be an early-career investigator. Focused on impactful research from basic to translational science, this opportunity is crucial for advancing SCI knowledge and interventions.

The FY26 Spinal Cord Injury Research Program Clinical Trial Award supports innovative clinical trials aimed at significantly improving spinal cord injury treatment. This funding opportunity encourages collaboration by allowing two Principal Investigators, including an early-career investigator, to drive the research forward. Applicants must partner with at least two SCI community members, ensuring that the project is informed by lived experiences and community needs throughout its development and implementation.

The FY26 Spinal Cord Injury Research Program Clinical Translation Research Award funds innovative clinical research aimed at bridging the gap to larger clinical trials. It focuses on accelerating the application of new techniques and improving patient outcomes through effective diagnosis and rehabilitation strategies. Key features include an Early-Career Partnership Option for principal investigators and a requirement for community partner involvement, ensuring collaborative research that meets real-world needs.

The Philanthropic Impact Fund (PIF) by Vanguard Charitable aims to strengthen nonprofit organizations and philanthropic infrastructure. It focuses on integrating AI, educating donors, and enhancing the narrative around the nonprofit sector. Grants typically range from $50,000 to $100,000, with larger requests considered. Organizations must be 501(c)(3) registered nonprofits to apply. This funding is a strategic investment in resilience and sustainability, addressing critical needs in the sector.

The Fordney Foundation Grant supports talented individuals in dance, aiming to foster professional careers and enhance community engagement in dance sports. Established in 2002, the foundation offers financial assistance to young dancers (ages 6-25) and promotes ballroom dancing across diverse ethnic backgrounds. Its DanceStart Program aids families in supporting their children's dance education at competitive levels, emphasizing the importance of physical conditioning and personal expression through this art form.

The Regenerative Agriculture Foundation Grant supports organizations that promote regenerative practices, emphasizing the value of people, plants, animals, and the planet. With a focus on BIPOC-led initiatives, the foundation encourages systemic change in agricultural systems through collaborative funding. Grants are available to U.S.-based organizations that align with RAF's vision and engage in transformative efforts. The competitive grantmaking process is by invitation only, ensuring targeted support for impactful projects.

The Coors Light Líderes Grant Program honors exceptional Latino leaders across the U.S. and Puerto Rico, awarding five individuals with a $10,000 grant each for their nonprofit organizations. This initiative, active for 17 years, aims to empower emerging leaders who demonstrate significant community impact through innovative programs. Eligible nominees must be between 21-39 years old, associated with a 501(c)(3) nonprofit, and committed to fostering positive change in their communities.

The purpose of America’s Healthy Food Financing Initiative (HFFI) is to improve access to healthy food in underserved areas, to support food supply chain resiliency, to create and preserve quality jobs, and torevitalize low-income communities by providing financial and technical assistance, either directly orthrough other partners and intermediaries, to eligible fresh, healthy food retailers and enterprises toovercome the higher costs and initial barriers to entry in underserved areas. HFFI offers fundingopportunities and technical assistance to eligible applicants.

The Make a SPLASH! Grant Contest invites municipal entities and non-profits in the U.S. to apply for the Inclusive Design Award. This award recognizes splash pads that prioritize inclusivity and accessibility. Winners will receive a customized Life Floor safety surface, valued at $50-65k, promoting community engagement and safety. With two opportunities to win, this initiative aims to enhance splash pad designs, ensuring they cater to all individuals. Join us in making splash pads safer and more accessible for everyone!