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Best Foundation Grants for Nonprofits in Missouri

Find the perfect Foundation grants for nonprofits in Missouri on Instrumentl. 10,000+ Foundation grants for nonprofits in Missouri in the United States.

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$2.59B

Total funding

$5K

Median grant

10,000+ grants
$2.59B total
$5K median

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Ryan White HIV/AIDS Program Part B AIDS Drug Assistance Program Training and Technical Assistance

US HHS: Health Resources & Services Administration (HRSA)
Federal Government
American Samoa, Guam +4 more
Up to US $750,000
The Ryan White HIV/AIDS Program Part B AIDS Drug Assistance Program Training and Technical Assistance aims to enhance the capacity of ADAPs. By providing essential tools and expert guidance, the program seeks to improve health outcomes for individuals living with HIV in an evolving healthcare landscape. This initiative is funded by the US HHS through the Health Resources & Services Administration, ensuring support and resources are effectively allocated to meet the needs of vulnerable populations.
HIV / AIDS

Syringe Service Program Grant

The Comer Family Foundation Inc
Private
District of Columbia, Puerto Rico +1 more
US $2,500 - US $20,000
The Syringe Service Program Grant, offered by The Comer Family Foundation, aims to enhance harm reduction initiatives by funding syringe access programs across the U.S. These programs provide sterile syringes, education, and support services to mitigate the risks associated with drug use, including HIV and hepatitis transmission. Priority is given to organizations in underserved areas and those led by marginalized communities. Grants are available for operational costs, program development, and staff training, with a focus on sustainability and local partnerships.
Drug Use Disorder

Miller Indigenous Economic Development Fellowship

Native Forward Scholars Fund
Association/Society
United States
Unspecified amount
The Miller Indigenous Economic Development Fellowship, established by the Native Forward Scholars Fund, provides financial assistance to American Indian and Alaska Native doctoral candidates engaged in economic research impacting Native communities. This fellowship supports costs associated with data collection, analysis, and travel. It aims to enhance the representation of Native scholars in economics, addressing the current underrepresentation in the field. Eligible candidates are encouraged to apply to further their research and contribute to their communities.
Education - Higher Education Academic Success & Enrichment Native American Services +3 more

Senator Harold “Potch” Wheeler Memorial Scholarship

Community Foundation of Whitley County
Association/Society
United States
Unspecified amount
The Senator Harold "Potch" Wheeler Memorial Scholarship, managed by the Community Foundation of Whitley County, honors the legacy of a dedicated public servant. This competitive scholarship is available annually to high school seniors from Whitley County who plan to pursue college education in public service or within the Indiana Department of Natural Resources. Recipients are chosen based on their embodiment of the ideals and character traits exemplified by Senator Wheeler.
Education - Higher Education Education - High School Academic Scholarship Programs +1 more

Ryan White HIV/AIDS Program Part D - Women, Infants, Children and Youth Grant Supplemental Funding (363415)

US HHS: Health Resources & Services Administration (HRSA)
Federal Government
American Samoa, Guam +4 more
Up to US $200,000
The Ryan White HIV/AIDS Program Part D provides supplemental funding aimed at enhancing the infrastructure and capacity of organizations to deliver high-quality, family-centered HIV care services. This initiative focuses on two key areas: HIV Care Innovation and Infrastructure Development, ensuring improved access to essential services for women, infants, children, and youth affected by HIV.
HIV / AIDS

Alliance for Innovation on Maternal Health (AIM) Capacity Program

Health Resources and Services Administration
Federal Government
American Samoa, Guam +4 more
Up to US $230,000
The Alliance for Innovation on Maternal Health (AIM) Capacity Program aims to enhance the capacity of state, territorial, and Tribal entities in the U.S. to implement and sustain AIM Patient Safety Bundles. By promoting evidence-based maternal safety practices, the program strives to improve the quality of maternity care, enhance maternal health outcomes, and significantly reduce preventable maternal mortality and severe morbidity.
Maternal And Perinatal Health Patient Safety

MIND Prize

The Pershing Square Foundation
Private
United States
US $750,000
The MIND Prize, funded by The Pershing Square Foundation, supports innovative research to combat neurodegenerative diseases like Alzheimer's. It empowers early-to-mid-career investigators to explore unconventional approaches and fosters collaboration across disciplines. Each winner receives $250,000 annually for three years, promoting advancements in neuroscience and creating a unique network for researchers. The initiative aims to enhance our understanding of brain health and tackle pressing societal challenges.
Neurological Diseases & Disorders Neuroscience Dementia & Alzheimer’s Disease

Scaling Pathways to Homeownership

Capital One Foundation
Corporate
American Samoa, Guam +4 more
US $200,000
  • Innovative: An approach that brings fresh thinking, tools, or models to homeownership in ways that challenge the status quo and demonstrate a disruptive, future-oriented vision with potential to inspire or shift broader field practice.
  • Impactful: A solution with meaningful potential to expand homeownership through knowledge and action, featuring clear and measurable progress indicators that demonstrate capacity to shift trajectories for low- and moderate-income households.
  • Bridge-Building: An initiative that effectively connects and unifies a wide range of stakeholders, fostering meaningful collaboration across sectors or perspectives. The strongest submissions will reflect strong community partnerships across the housing ecosystem.
  • Durable: A sustainable pathway that addresses root causes of homeownership barriers rather than just symptoms, with compelling evidence of potential to elicit robust support from broad private, philanthropic, and public funding sources over time.
Homeownership Equitable & Affordable Housing

Ryan White HIV/AIDS Program (RWHAP) Integrated HIV/AIDS Planning Resource Allocation Cooperative Agreement

US HHS: Health Resources & Services Administration (HRSA)
Federal Government
American Samoa, Guam +4 more
Up to US $700,000
The Ryan White HIV/AIDS Program (RWHAP) Integrated HIV/AIDS Planning Resource Allocation Cooperative Agreement aims to enhance the effectiveness of HIV prevention and care planning for RWHAP Parts A and B recipients. Through the provision of training, tools, and technical assistance, this initiative seeks to optimize resource allocation and strengthen the overall system of HIV care and treatment, ultimately improving health outcomes for those affected by HIV.
HIV / AIDS

AIDS Drug Assistance Program (ADAP) Emergency Relief Funds (ERF) (363159)

US HHS: Health Resources & Services Administration (HRSA)
Federal Government
American Samoa, Guam +4 more
Up to US $10,000,000
The AIDS Drug Assistance Program (ADAP) Emergency Relief Funds aim to provide essential funding to states and territories. This initiative focuses on preventing, reducing, or eliminating waiting lists for ADAP services, ensuring timely access to necessary medications and support for individuals living with HIV/AIDS. This program addresses critical funding shortfalls, enhancing the healthcare infrastructure and improving health outcomes in affected communities.
HIV / AIDS

Ryan White HIV/AIDS Program Part C Capacity Development Program (363166)

US HHS: Health Resources & Services Administration (HRSA)
Federal Government
American Samoa, Guam +4 more
Up to US $150,000
The Ryan White HIV/AIDS Program Part C Capacity Development Program aims to enhance the capabilities of community-based organizations, focusing on improving health outcomes and decreasing HIV transmission. This initiative supports individuals who have not yet accessed regular HIV care, emphasizing innovative care solutions and infrastructure development to address these critical needs.
HIV / AIDS

HIV Care Grant Program - Part B States/Territories Formula and AIDS Drug Assistance Program Formula and AIDS Drug Assistance Program Supplemental Awards

US HHS: Health Resources & Services Administration (HRSA)
Federal Government
American Samoa, Guam +7 more
Unspecified amount
The HIV Care Grant Program, funded by the US HHS: Health Resources & Services Administration (HRSA), aims to enhance access to high-quality HIV care and treatment for low-income individuals. This initiative supports states and territories in developing comprehensive systems to address the needs of those living with HIV. By providing essential resources, the program seeks to improve health outcomes and ensure that vulnerable populations receive the necessary support and services.
HIV / AIDS

Ryan White HIV/AIDS Program Part B States/Territories Supplemental Grant Program (363163)

US HHS: Health Resources & Services Administration (HRSA)
Federal Government
American Samoa, Guam +4 more
Up to US $9,000,000
The Ryan White HIV/AIDS Program Part B Supplemental Grant aims to provide essential funding to support HIV care and treatment services across states and territories. This program supplements existing formula-based funding from the RWHAP Part B and ADAP, improving access to necessary resources for those affected by HIV/AIDS. By enhancing support structures, it addresses critical healthcare needs, ensuring better health outcomes for vulnerable populations.
HIV / AIDS

Identifying the Effects of GLP-1 Medications Among Individuals with Cardiovascular, Kidney and Metabolic Disease

American Heart Association
Association/Society
United States
Up to US $300,000
The American Heart Association is inviting proposals for research on the effects of GLP-1 and GIP agonists in individuals with cardiovascular, kidney, and metabolic diseases. This initiative aims to explore how these medications can alleviate the CKM burden. Researchers with expertise in causal inference, machine learning, and cardiovascular research are encouraged to apply, particularly those working in multidisciplinary teams and leveraging various data sources.
Cardiovascular Diseases & Systems Endocrine & Metabolic Diseases Kidney Diseases

Fruit of the Vine Scholarship

Napa Valley Community Foundation
Private
United States
US $2,000 - US $4,000

Napa Valley Community Foundation

There are more than 800 Community Foundations in the US, each devoted to a specific region. We operate independently, with a common goal in mind: to be a platform for local people who want to pay it forward. To deliver resources to effective charitable programs. And to make our communities stronger and more successful by doing these two things.

Among our peers, Napa Valley Community Foundation ranks first on several key measures of donor satisfaction and impact, according to a recent donor survey conducted by the Center for Effective Philanthropy. Our donors say that we deeply understand their interests, and deeply understand the needs of Napa Valley. That, in a nutshell, is our job.

Fruit of the Vine Scholarship

The Fruit of the Vine Scholarship Fund benefits graduating Napa County high school seniors and Napa Valley College transfer students who will find the cost of higher education a financial hardship. Consideration is given to applicants who are the first in their family to attend college or are employed (or have a parent or guardian who is employed) in the Napa County wine or grape industry. Recipients of the scholarship will receive funding for up to four years of undergraduate study.

Education - Higher Education Viticulture Academic Scholarship Programs +1 more

Little Giraffe Foundation: NICU Support Grants

Little Giraffe Foundation
Private
United States
Up to US $2,000
The Little Giraffe Foundation, a national non-profit based in Chicago, provides NICU Support Grants ranging from $100 to $1,000. Since 2011, they have positively impacted countless families by delivering over 32,000 gift bags and funding essential research. These grants aim to enhance the experience for parents and patients in neonatal intensive care units, supporting initiatives like holiday gift bags and resources for bonding with babies. Applications are welcomed from eligible U.S.-based institutions.
Obstetrics & Neonatal Care

Neonatal Research Initiative- RFP

Little Giraffe Foundation
Private
United States
US $5,000 - US $10,000
The Little Giraffe Foundation is dedicated to supporting neonatal health through research grants ranging from $5,000 to $10,000. Since 2011, they have provided substantial resources to hospitals and institutions, focusing on both immediate and long-term health challenges faced by premature infants. Eligible applicants include scientists and healthcare professionals from U.S.-based institutions. The foundation aims to advance research in biological processes, genetics, clinical studies, and more, improving outcomes for vulnerable populations.
Obstetrics & Neonatal Care

Encompass Health Therapy Grant

Encompass Health Corporation
Corporate
Puerto Rico, United States
Up to US $75,000
The Encompass Health Therapy Grant offers up to $50,000 for research on the effectiveness of therapies in inpatient rehabilitation facilities. This funding aims to enhance understanding of neurological impairments and improve patient outcomes through evidence-based practices. Eligible projects must be conducted in the U.S. or Puerto Rico, require a defined research protocol, and adhere to ethical standards. The grant prioritizes studies on therapy impact, implementation science, and caregiver education, contributing to the advancement of rehabilitation care.
Medical Rehabilitation Home Health Care Health Care Access & Delivery +3 more

Turkey Distribution 2026

Islamic Relief Usa
Private
United States
Unspecified amount

A funding opportunity designed to support food security, refugee services, licensed free healthcare clinics and community development organizations in the United States.

Turkey Distribution 2026

IRUSA facilitates annual Turkey Distributions in cities across the United States during Thanksgiving. IRUSA will procure and deliver turkeys to partners that will deliver them onto people in need. Along with turkeys, partner organizations may distribute other Thanksgiving goods to assist individuals and families who may not have access to these food items. The distribution may occur with regular food pantry distribution dates or as its own event. The goal of this event is to not only address food insecurity in local communities but to also embody the season of giving by bringing the holiday festivities to those who would otherwise not be able to enjoy a Thanksgiving meal in their homes.

Food Security Food Delivery & Distribution Services

Summer Food Service Program (SUN) program 2026

Islamic Relief Usa
Private
United States
Unspecified amount

A funding opportunity designed to support food security, refugee services, licensed free healthcare clinics and community development organizations in the United States.

Summer Food Service Program (SUN) program 2026

The Summer Food Service Program (SUN), created and funded by the United States Department of Agriculture (USDA), currently provides organizations with limited funding opportunities to purchase and provide meals to their local communities in the form of reimbursements. Starting in 2011, IRUSA began to supplement and support the USDA in this effort. SUN recipient, organizations are able to start a USDA-approved site, increase the capacity of their current USDA-approved site(s) or develop their role as the meal-providing sponsor to subgrantees. Grants are provided to further enable and encourage wider participation in this program as well as increase food access and support to food-insecure children throughout the summer months. 

Food Security Food Delivery & Distribution Services

Corporate Giving - Charitable Contributions

McCormick & Company, Inc
Corporate
United States
Unspecified amount
McCormick & Company, Inc. actively supports charitable contributions through its Charitable Donations Committee (CDC), which prioritizes donations to non-profit organizations that enhance education, health, environment, and culture. The CDC focuses on organizations that benefit communities where McCormick employees live and work, ensuring a positive impact. Eligible groups must be tax-exempt and demonstrate a commitment to non-discrimination. However, donations are not made to individuals, political organizations, or entities that conflict with corporate values.
Environment Art & Culture Health & Medicine +4 more

Enhancing Pastoral and Social Ministry Grants

Catholic Extension
Association/Society
Acadia Parish, Louisiana, Accomack County, Virginia +994 more
Unspecified amount
Catholic Extension's Enhancing Pastoral and Social Ministry Grants aim to empower the church to broaden its outreach and foster societal transformation through targeted pastoral and social initiatives. This program supports specific elements of the church's ministerial efforts, including funding for catechetical resources, marriage and family ministries, and social outreach for vulnerable populations. By investing in these areas, Catholic Extension seeks to enhance the church's role in communities, especially following disasters.
Catholicism Family Services Homelessness Services +3 more

Irene & Marie Oberweis Nursing Scholarship Endowment Fund

Community Foundation of the Fox River Valley
Private
United States
Unspecified amount

Community Foundation of the Fox River Valley

The Community Foundation of the Fox River Valley is a collection of individual funds and resources given by local citizens to enhance and support the quality of life in the Fox River Valley of Illinois.

We are a tax-exempt public charity that allows individuals, businesses, and non-profit organizations to establish permanent endowments and temporary funds within the confines of one large foundation.

Foundation funds are used to provide grants to non-profit organizations and scholarships to area students. The Foundation also hosts a Youth Engagement in Philanthropy (YEP) program, which helps high school students learn more about philanthropy and empowers them to make a difference in the community.

The Community Foundation of the Fox River Valley serves the City of Aurora, Kane County, and Kendall County within the State of Illinois.

Irene & Marie Oberweis Nursing Scholarship Endowment Fund

This scholarship was created by Marie Oberweis as a loving tribute to her sister Irene.

Marie Oberweis (1921-2007) graduated from Madonna High School in 1939.

That year, she started her career with Oberweis Dairy where she later became a partner with her father Peter Oberweis and her brother Joseph Oberweis.

Irene Oberweis (1924-1996) attended Annunciation School in Aurora. She spent many years of her life in hospitals due to fragile health.

In gratitude for the exemplary care her sister received throughout her lifetime from those in the nursing profession, Marie Oberweis created a permanent scholarship fund to support area students entering the nursing field.

Education - Higher Education Career / College Preparation Education - High School +2 more

Patrice Faye Cohen Memorial Scholarship Award

Jewish Community Foundation
Private
United States
Unspecified amount
The Patrice Faye Cohen Memorial Scholarship Award supports high school women from Southern New Jersey who are pursuing college education with a focus on entrepreneurship. Established in memory of Patrice Faye Cohen, a successful business owner, this scholarship aims to empower women to achieve their entrepreneurial dreams. Eligible candidates must demonstrate a commitment to their studies and entrepreneurial aspirations, with financial support available for tuition and related expenses.
Education - Higher Education Education - High School Academic Scholarship Programs +2 more

Spearfish Volunteer Firefighters' Association Scholarship

South Dakota Community Foundation
Private
United States
Unspecified amount

South Dakota Community Foundation

As a statewide community foundation, we work with donors, nonprofits and community leaders to strengthen philanthropy in South Dakota every day.

Scholarships

At South Dakota Community Foundation (SDCF), we proudly manage more than 350 scholarship funds in partnership with generous donors who are committed to supporting students. These scholarships offer countless opportunities to help ease the financial burden of continuing their education.

Spearfish Volunteer Firefighters' Association Scholarship

To provide financial support to individuals pursuing an education and training in the public safety industry.

The Spearfish Fire Department, established in the late 1880s as a volunteer organization, serves the northern Black Hills in western South Dakota. Its mission is to protect lives and property within the fire protection district and mutual aid area. Additionally, the department advocates for fire safety and provides fire safety education in local schools and the wider community.

Education - Higher Education Vocational & Trade Education Fire Ecology +1 more

Emma E. Hill Memorial Scholarship Fund

Chester County Community Foundation
Private
United States
Unspecified amount

Emma E. Hill Memorial Scholarship Fund

Mission Statement

The Emma E. Hill Memorial Scholarship Fund was established to memorialize Emma by helping female swimmers pursue their dreams of a college education. The scholarship awards will be granted on an annual basis to female graduating high school senior athletes in Southern Chester County.

About Emma

Emma was an excellent student as a sophomore at Unionville High School (UHS). She loved to swim and was a dedicated member of both the Kennett YMCA Sea Dragons and UHS swim teams. In her spare time, Emma was a lifeguard and also taught young children how to swim at the Y. As a younger child and teenager, Emma excelled on the ballfield in URA softball.

At the young age of 16, Emma passed away following complications caused by a rare type of gastric cancer, a form of the disease that was unheard of in a child and unfortunately found too late. Throughout Emma’s brief illness, she was strong and determined to get better, and did not let her health issues define her in any way.

Emma was beautiful in every sense of the word, and was loved throughout her community and beyond. She worked hard at whatever she was trying to accomplish, but always with a cheery, exuberant attitude and lovely smile. More than anything, her absolute kindness and warm heart are what made Emma our sweet girl.

Education - Higher Education Women & Girl Services Swimming +2 more

The Save Mart Companies CARES Foundation Grant

Save Mart Cares
Private
California, Oregon +2 more
US $500 - US $10,000

About

With deep roots in California’s Central Valley, The Save Mart Companies and its family of stores prides itself in being a part of neighborhoods and putting people first. Our dedication to customers is reflected in the connections we’ve made in the communities we’ve served for more than 70 years.

The Save Mart Companies CARES Foundation

In 2000, we established The Save Mart Companies CARES Foundation, our philanthropic, non-profit organization, supporting programs and organizations that provide vital resources for children and families in the communities we serve. The CARES Foundation focuses on building stronger communities through fresh foods, accessibility, and programs that support youth and helping them to thrive. Annually, The CARES Foundation contributes approximately $500,000 in small grants to support community-based, non-profit organizations.

The Save Mart Companies CARES Foundation Grant

The CARES Foundation’s focus is building stronger communities through fresh foods, access to food, and programs that support youth and helping them thrive.

The CARES Foundation will review, on a quarterly basis, among other things, the breadth of the audience served; the likely impact in the community; the importance of the need to be addressed in the community; and the community reputation, service history, and financial stability of the group or program seeking funds. No one of these or other factors will necessarily be weighted more heavily than another. Instead, each group or program will be measured against all groups and 2 programs seeking funding at the time. For example, a program serving a small segment of the community but that addresses an especially important community need, and thus has the potential for a strong and meaningful impact, would be favored over a group serving a wider clientele but that fills a less important community need. Requests for Grants should be a minimum of $500.00 up to $10,000.00. Programs and organizations requesting smaller grants should contact the Store Manager of the nearest Save Mart Companies’ store location for request consideration.

Recipients that receive grants for more than one year must demonstrate meaningful outcomes for the previous investment made by The CARES Foundation.

Food Access & Hunger Youth Services Family Services +1 more

Foundation Grants for Nonprofits in Missouri Highlights

Looking for foundation grants for nonprofits in Missouri?


Read more about each grant below or start your 14-day free trial to see all foundation grants for nonprofits in Missouri recommended for your specific programs.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Foundation Grants for Nonprofits in Missouri

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

100+ Foundation grants for nonprofits in Missouri grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

37 Foundation grants for nonprofits in Missouri over $25K in average grant size

29 Foundation grants for nonprofits in Missouri over $50K in average grant size

25 Foundation grants for nonprofits in Missouri supporting general operating expenses

100+ Foundation grants for nonprofits in Missouri supporting programs / projects

2,000+ Grants on Instrumentl focused on Health & Medicine

3,000+ Grants on Instrumentl focused on Education

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Foundation grants for Nonprofits in Missouri?

Most grants are due in the first quarter.

Q1
33.7%
Q2
26.8%
Q3
18.7%
Q4
20.8%

Typical Funding Amounts

What's the typical grant amount funded for Foundation Grants for Nonprofits in Missouri?

Grants are most commonly $13,750.

$375 $375 Min.
$13,750 $13.8 K Median
$587,301 $587.3 K Average
$40,331,313 $40.3 M Max.

Average Grant Size

What's the typical amount funded for Missouri?

Grants are most commonly $101,542.

$101,542

Total Number of Grants

What's the total number of grants in Foundation Grants for Nonprofits in Missouri year over year?

In 2024, funders in Missouri awarded a total of 44,064 grants.

2022 39,922

2023 39,688

2024 44,064

Top Grant Focus Areas

Among all the Foundation Grants for Nonprofits in Missouri given out in Missouri, the most popular focus areas that receive funding are Philanthropy, Voluntarism & Grantmaking Foundations, Education, and Human Services.

1. Philanthropy, Voluntarism & Grantmaking Foundations

2. Education

3. Human Services

Funding Over Time

How is funding for Foundation Grants for Nonprofits in Missouri changing over time?

Funding has increased by -15.61%.

2022 $4,698,402,122

2023 $5,287,874,816
12.55%

2024 $4,462,369,205
-15.61%

Missouri Counties That Receive the Most Funding

How does grant funding vary by county?

St Louis County, Jackson County, and St Louis City receive the most funding.

County Total Grant Funding in 2024
St Louis County $2,185,711,864
Jackson County $1,234,679,326
St Louis City $1,054,441,922
Greene County $223,079,775
Clay County $178,423,081